Pharmacology News

December 20, 2025

Top Headlines

A New Way to Prevent Gum Disease Without Wiping Out Good Bacteria

Dec. 16, 2025 Scientists are uncovering a surprising way to influence bacteria—not by killing them, but by changing how they communicate. Researchers studying oral bacteria found that disrupting chemical signals used in bacterial “conversations” can shift ...

Ozempic May Offer a Surprising Bonus Benefit for Brain Health

Dec. 13, 2025 A new analysis suggests that people with type 2 diabetes who use GLP-1 medications like Ozempic, Trulicity or Victoza may be less likely to develop epilepsy than those taking DPP-4 inhibitors. Semaglutide showed the strongest connection to lowered ...

Scientists Reveal the Real Benefits and Hidden Risks of Medical Cannabis

Dec. 12, 2025 A sweeping review of more than 2,500 studies reveals that despite booming public enthusiasm, cannabis has strong scientific support for only a few medical uses, leaving most popular claims—like relief for chronic pain, anxiety, and insomnia—on ...

Nerve Injuries Can Trigger Hidden Immune Changes Throughout the Entire Body

Dec. 11, 2025 Researchers discovered that nerve injuries can alter the immune system throughout the body, and males and females react very differently. Male mice showed strong inflammatory responses, while females showed none, yet both transmitted pain-inducing ...

Simple Supplement Mix Shows Remarkable Results in Brain Cancer

Dec. 10, 2025 New research is challenging one of medicine’s oldest assumptions: that cancer must be attacked to be cured. By treating glioblastoma patients with a simple combination of resveratrol and copper, the researchers found dramatic reductions in tumor ...

Her Food Cravings Vanished on Mounjaro Then Roared Back

Dec. 8, 2025 Deep-brain recordings showed that Mounjaro and Zepbound briefly shut down the craving circuits linked to food noise in a patient with severe obesity. Her obsessive thoughts about food disappeared as the medication quieted the nucleus accumbens, the ...

Garlic Mouthwash Shows Shockingly Strong Germ-fighting Power

Dec. 8, 2025 Garlic extract is emerging as a surprisingly powerful contender to chlorhexidine, the long-standing “gold standard” in antimicrobial mouthwashes. A systematic review of clinical studies shows that higher-concentration garlic mouthwash can rival ...

Is Your Gut Being Poisoned? Scientists Reveal the Hidden Impact of Everyday Chemicals

Dec. 2, 2025 Researchers discovered that 168 common chemicals can disrupt the growth of beneficial gut bacteria, with some also promoting antibiotic resistance. Many of these substances—found in food, water, ...

A 70-year-old Pregnancy Drug Just Revealed a Hidden Weakness in Brain Cancer

Dec. 2, 2025 Researchers have solved the decades-old mystery behind how a common pregnancy drug lowers blood pressure. It turns out the medication blocks a fast-acting “oxygen alarm” inside cells. That same ...

Fast Depression Relief? Nitrous Oxide Shows Remarkable Potential

Dec. 2, 2025 Nitrous oxide may offer quick, short-term relief for people with major depression, especially those who haven’t responded to standard medications. The meta-analysis found rapid improvements after a single dose and more sustained benefits after ...

Your Skin Has a Built-in Cancer Defense and Sunlight Turns It Off

Nov. 30, 2025 Scientists have uncovered how too much sunlight can flip a hidden switch inside skin cells that makes inflammation spiral out of control and increases the risk of cancer. Their research reveals that UV radiation breaks down a protective protein ...

Hidden Blood Molecules Show Surprising Anti-aging Power

Nov. 29, 2025 Scientists have identified new anti-aging compounds produced by a little-studied blood bacterium. These indole metabolites were able to reduce inflammation, oxidative stress, and collagen-damaging activity in skin cell cultures. Three of the ...

Latest Headlines

updated 12:13pm EST

Cannabis Compounds Show Unexpected Power Against Ovarian Cancer

Dec. 15, 2025 Scientists have discovered that key compounds from cannabis—CBD and THC—show surprisingly strong effects against ovarian cancer cells. Used together, they slow cell growth, reduce colony ...

Mayo Clinic Neurosurgeon Reveals 8 Back Pain Myths to Stop Believing

Dec. 15, 2025 Back pain is wrapped in persistent myths, but many are far from the truth. From misconceptions about heavy lifting and bed rest to confusion over posture, exercise, and surgery, Dr. Meghan Murphy ...

Stem Cell Pain Sponge Soaks Up Osteoarthritis Joint Pain and Protects Cartilage

Dec. 15, 2025 SereNeuro Therapeutics revealed promising results for SN101, a first-in-class iPSC-derived therapy designed to treat chronic osteoarthritis pain ...

Low Dose Melanoma Treatment Delivers Dramatically Better Results

Dec. 8, 2025 Using less ipilimumab appears to make melanoma immunotherapy both safer and more effective, with dramatically better response and survival outcomes. The findings suggest that reducing side effects ...

The Rotten Egg Smell That Could Finally Beat Nail Fungus

Dec. 7, 2025 Researchers have identified hydrogen sulfide as a surprisingly effective tool for treating difficult nail infections. It penetrates nails more efficiently than current drugs and kills pathogens by ...

Millions Are About to Choose the Wrong Medicare Plan

Nov. 29, 2025 Millions face Medicare decisions each year, but many don’t take advantage of tools that can save them money and stress. Insurance marketing often overshadows unbiased options like SHIP, leaving ...

Scientists Find Toxic Metals Hidden in Popular Plastic Toys

Nov. 28, 2025 A large-scale Brazilian study found dangerous levels of toxic metals in popular children’s toys, with barium and lead topping the list. Researchers used sophisticated lab methods to identify 21 ...

Nov. 28, 2025 A major review across 73 countries finds that access to antiseizure medications is rising, but safe prescribing isn’t keeping pace. Valproate—linked to serious birth defects—remains widely used ...

Bird Flu’s Surprising Heat Tolerance Has Scientists Worried

Nov. 28, 2025 Researchers discovered why bird flu can survive temperatures that stop human flu in its tracks. A key gene, PB1, gives avian viruses the ability to replicate even at fever-level heat. Mice ...

New Study Shows Rheumatoid Arthritis Begins Long Before Symptoms

Nov. 26, 2025 Rheumatoid arthritis begins years before pain ever appears, and scientists have now mapped the hidden immune battle that unfolds long before symptoms. By studying people with RA-linked antibodies ...

Immune Cells Use a Surprising Trick to Heal Muscle Faster

Nov. 24, 2025 A research team has found that specific immune cells can connect with muscle fibers in a lightning-fast, neuron-like way to promote healing. These cells deliver quick pulses of calcium, triggering ...

New Nasal Nanodrops Wipe out Brain Tumors in Mice

Nov. 22, 2025 A new nasal-delivered nanotherapy shows promise against aggressive glioblastoma tumors. By activating the STING immune pathway using gold-core spherical nucleic acids, researchers were able to reach ...

Simple Amino Acid Supplement Greatly Reduces Alzheimer’s Damage

Nov. 21, 2025 Researchers discovered that the common amino acid arginine can block harmful Aβ aggregation and reduce its toxic effects in Alzheimer’s disease models. In flies and mice, oral arginine lowered ...

A Drug Already in Trials May Stop Chemotherapy Nerve Damage

Nov. 21, 2025 Researchers discovered that chemotherapy can accidentally trigger a stress alarm in immune cells, causing inflammation that damages nerves. Blocking this alarm protected mice from nerve pain and kept ...

A Tiny Enzyme May Hold the Key to Safer Pain Relief

Nov. 23, 2025 Researchers have uncovered a surprising way the brain switches pain on, revealing that neurons can release an enzyme outside the cell that activates pain signals without disrupting normal movement or ...

Tiny Microneedle Patch Dramatically Improves Heart Attack Recovery

Nov. 21, 2025 Researchers created a dissolvable microneedle patch that delivers IL-4 directly to damaged heart tissue, jump-starting repair after a heart attack. The targeted approach shifts immune cells into a ...

Inflammation Turns Bone Marrow Into a Breeding Ground for Disease

Nov. 19, 2025 Researchers discovered that chronic inflammation fundamentally remodels the bone marrow, allowing mutated stem cell clones to quietly gain dominance with age. Reprogrammed stromal cells and ...

How to Keep Ozempic/Wegovy Weight Loss Without the Nausea

Nov. 18, 2025 Scientists are uncovering how GLP-1 drugs like Ozempic and Wegovy act on brain regions that control hunger, nausea, pleasure-based eating, and thirst. These discoveries may help create treatments ...

Chronic Pain May Dramatically Raise Your Blood Pressure

Nov. 17, 2025 Chronic pain might quietly push people toward developing high blood pressure—and the more widespread the pain, the greater the danger. A massive analysis of over 200,000 adults uncovered strong ...

A Tiny Ancient Virus Reveals Secrets That Could Help Fight Superbugs

Nov. 17, 2025 Scientists mapped the Bas63 bacteriophage in unprecedented detail, uncovering how its tail machinery infects bacteria. The structure reveals rare whisker-collar features and distant evolutionary ties ...

Simple Molecule Shows Remarkable Alzheimer’s Reversal in Rats

Nov. 19, 2025 Scientists have developed a new molecule that breaks down beta-amyloid plaques by binding to excess copper in the brain. The treatment restored memory and reduced inflammation in rats, while also ...

Scientists Reverse Kidney Damage in Mice, Hope for Humans Next

Nov. 14, 2025 Researchers uncovered how fatty molecules called ceramides trigger acute kidney injury by damaging the mitochondria that power kidney cells. By altering ceramide metabolism or using a new drug ...

Scientists Reveal a Hidden Hormone Switch for Learning

Nov. 21, 2025 Researchers uncovered how estrogen subtly reshapes learning by strengthening dopamine reward signals in the brain. Rats learned faster when estrogen levels were high and struggled when the ...

New Evidence Shows Tirzepatide and Semaglutide Strongly Protect the Heart

Nov. 21, 2025 A massive real-world study comparing tirzepatide and semaglutide reveals both drugs deliver strong, early cardiovascular protection—reducing heart attack, stroke, and death in adults with type 2 ...

Strange Microscopic Structures Found in Long COVID Blood

Nov. 12, 2025 Scientists have discovered strange microscopic structures in the blood of people with Long COVID—clusters of tiny microclots tangled together with sticky immune webs known as neutrophil ...

Doctors Found a Way to Stop a Deadly Metformin Reaction

Nov. 9, 2025 A hospital in Thailand created a quick-action dialysis protocol for patients with metformin-associated lactic acidosis, a dangerous reaction to a common diabetes drug. The program sharply reduced ...

A Surprising CBD Advance Calms Pain Without Side Effects

Nov. 18, 2025 Researchers developed a new nano-micelle formulation, CBD-IN, that finally gets CBD into the brain effectively. In mice, it relieved neuropathic pain quickly and didn’t cause the usual movement or ...

Scientists Discover Metformin May Block Key Exercise Benefits

Nov. 18, 2025 Rutgers scientists found that metformin can blunt many of the metabolic and cardiovascular improvements normally produced by exercise. Participants who took the drug saw reduced gains in fitness, ...

Scientists Find 15 Gut Bacteria That May Drive Heart Disease

Nov. 12, 2025 Scientists in Seoul have uncovered 15 gut bacterial species linked to coronary artery disease, showing that microbes can influence heart health far beyond digestion. Their findings reveal how shifts ...

Blocking a Single Protein Forces Cancer Cells to Self-Destruct

Nov. 20, 2025 Researchers uncovered a powerful weakness in lung cancer by shutting down a protein that helps tumors survive stress. When this protein, FSP1, was blocked, lung tumors in mice shrank dramatically, ...