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Controlled Substances News

October 11, 2026

Top Headlines

 

Depression may not be one biological condition, but several distinct patterns of brain activity hiding under the same diagnosis. Researchers studying 263 people with depression identified five brain profiles, each showing different patterns of ...
Researchers at Yale have identified a promising new approach to osteoarthritis that could do more than simply ease pain. The epilepsy drug lacosamide appears to block a protein involved in both pain signaling and cartilage destruction, helping ...
Cannabinoids may intensify anxiety by removing a natural brake on specific neurons in the brain’s fear center, particularly during stressful situations. In mice, shutting down those neurons sharply reduced cannabinoid-related anxious ...
A review of more than 265,000 people found that cannabis use was associated with higher rates of both committing violence and becoming a victim of it. The researchers say the link is significant but does not prove cannabis itself is the ...
A massive MRI study found that Alzheimer’s disease, mild cognitive impairment, psychiatric disorders, and addiction are associated with distinct patterns of accelerated brain aging. The strongest effects appeared in Alzheimer’s and mild ...
Scientists discovered rare flavoalkaloids in Cannabis leaves for the first time, along with dozens of other phenolic compounds that had never been reported in the plant. The findings suggest that ...
Researchers have found evidence that long COVID may damage dopamine releasing neurons in the brain, potentially explaining persistent fatigue, low motivation, slowed movement, and memory difficulties. The discovery could lead to new treatments that ...
A major Ontario study found 24 common medication chains in which one drug’s side effects can be mistaken for a new medical problem, leading to another prescription. Researchers say closer medication reviews, pharmacist involvement, and automated ...
Scientists in Japan have identified a natural compound found in blueberries, grapes, and other berries that may help muscle cells burn excess fat instead of storing it. The compound, pterostilbene, reduced abnormal fat buildup in cultured mouse ...
Early-life stress may physically alter how DNA is packaged in the brain, leaving stress-related genes primed to activate more easily years later. In mice, researchers were able to block this effect, preventing the heightened anxiety and stress ...
A massive analysis involving more than 100 million people has found strong links between recreational drug use and stroke, including among younger adults. Cocaine was associated with nearly double the risk of stroke, amphetamines with more than ...
Ozempic-like drugs appear to weaken more than hunger—they may also reduce cravings for alcohol and other addictive substances. Scientists are increasingly tracing this effect to the lateral septum, a brain region that helps connect memories and ...

Latest Headlines

updated 2:39am EDT

Earlier Headlines

 

A new experimental vaccine developed by Scripps Research could offer a powerful new way to prevent fentanyl overdoses by stopping the drug before it reaches the brain. Rather than targeting only ...

Using cannabis edibles and alcohol together may make drivers far more impaired than either substance alone, according to new research from Johns Hopkins. Even more concerning, common field sobriety ...

A little-known tree from Brazil’s Atlantic Forest may hold a surprising weapon against COVID-19. Researchers discovered that compounds called galloylquinic acids, extracted from its leaves, can ...

Melanoma may not become steadily more dangerous with age as scientists once assumed. In a surprising discovery, researchers found that cancer spread was lowest in young mice, surged in middle-aged ...

The largest review of medicinal cannabis to date found it doesn’t effectively treat anxiety, depression, or PTSD—despite millions using it for those reasons. Researchers warn it could even make ...

THC doesn’t just blur memories—it can create new ones that never happened. In a controlled experiment, cannabis users were much more likely to recall words that were never shown and struggled ...

Scientists are exploring a new way to harness the medical promise of psychedelic compounds without the mind-bending side effects. Researchers created modified versions of psilocin — the active form ...

A massive study of more than 600,000 U.S. veterans suggests that popular GLP-1 drugs such as semaglutide may do far more than help with diabetes and weight loss—they could also fight addiction ...

Researchers have discovered a new way to increase a key brain protein damaged in Rett syndrome, a rare genetic disorder that affects thousands of children worldwide. Early studies in mice and ...

Cocaine addiction isn’t simply a failure of willpower — it’s the result of lasting biological changes in the brain. Researchers at Michigan State University discovered that repeated cocaine use ...

Scientists are taking a closer look at the pill forms of Wegovy and Ozempic. In an animal study, the ingredient SNAC, which helps semaglutide survive the stomach and enter the bloodstream, was ...

A sweeping new study has uncovered a troubling mix of hazardous chemicals in popular hair extensions, including products made from human hair. Researchers detected dozens of substances linked to ...

A groundbreaking clinical trial is testing whether specially engineered stem cells can help the brain restore its own dopamine production in people with Parkinson’s disease. Because the condition ...

Scientists at Keck Medicine of USC are testing an experimental stem cell therapy that aims to restore the brain’s ability to produce dopamine, the chemical whose loss drives Parkinson’s disease. ...

New research using rhesus monkeys suggests that the brain’s relationship with alcohol may begin forming long before a person ever takes a drink. Scientists found that exposure to alcohol before ...

Scientists have developed a new way to fight gum disease without wiping out the mouth’s helpful bacteria—a major shift from traditional treatments. Instead of killing everything, this targeted ...

A new University at Buffalo study suggests cannabis-infused beverages could help some people cut back on alcohol. In a survey of cannabis users, those who drank cannabis beverages reported cutting ...

Cannabis-based medicines have been widely promoted as a potential answer for people living with chronic nerve pain—but a major new review finds the evidence just isn’t there yet. After analyzing ...

UC Davis researchers created brand-new psychedelic-like compounds by shining UV light on amino acid-based molecules. These compounds activated key serotonin receptors tied to brain plasticity and ...

Scientists have developed a new gene therapy that quiets pain at its source in the brain—without the addictive risks of opioids. Using AI to map how pain is processed, they created a targeted ...

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