Bone and Spine News

June 3, 2025

Top Headlines

Scientists Design Gene Delivery Systems for Cells in the Brain and Spinal Cord

May 21, 2025 — Research teams have created a versatile set of gene delivery systems that can reach different neural cell types in the human brain and spinal cord with exceptional accuracy. These delivery systems ...

A Step Forward in Treating Serious Genetic Disorders Prenatally

May 14, 2025 — Evidence is mounting that clinicians can treat serious genetic disorders prenatally by injecting medicine into the amniotic fluid, thus preventing damage that begins in ...

Discovering the Role of microRNA-27a in Tissue Regeneration and Bone Healing

May 8, 2025 — MicroRNA-27a has been shown to stimulate both the wingless-type integration site family, or Wnt signaling, and the bone morphogenetic protein pathways to actively promote bone regeneration, according ...

Experimental Painkiller Could Outsmart Opioids -- Without the High

May 19, 2025 — A study shows a non-opioid pain reliever blocks pain at its source -- calming specific nerve signals that send pain messages to the brain. In mice, the compound SBI-810 eased pain from surgery, bone fractures, and nerve injury without causing ...

Latest Headlines

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Klotho: A Protein That Promotes Healthy Aging and Improves Longevity

May 7, 2025 — An international study has shown that increasing levels of the Klotho protein in mice extends lifespan and improves both physical and cognitive health when ...

New Machine Algorithm Could Identify Cardiovascular Risk at the Click of a Button

Apr. 29, 2025 — An automated machine learning program has been able to identify potential cardiovascular incidents or fall and fracture risks based on bone density ...

Brain Decoder Controls Spinal Cord Stimulation

Apr. 28, 2025 — A lab develops brain wave decoder that may help in spinal cord injury ...

Scientists Develop New Bone Marrow Imaging Technique

Apr. 24, 2025 — A new bone marrow imaging technique could change treatment for cancer, autoimmune disease and musculoskeletal ...

Drugs Targeting 'Zombie Cells' Show Promise for Treating Chronic Back Pain

Apr. 22, 2025 — In a preclinical study, two drugs targeting 'zombie cells' have been shown to treat the underlying cause of chronic low back pain. The condition affects millions of people worldwide. Current ...

Building 'Cellular Bridges' for Spinal Cord Repair After Injury

Apr. 21, 2025 — Capitalizing on the flexibility of tiny cells inside the body's smallest blood vessels may be a powerful spinal cord repair strategy, new research ...

Titanium Particles Are Common Around Dental Implants

Apr. 9, 2025 — Titanium micro-particles in the oral mucosa around dental implants are common. This is shown in a new study which also identified 14 genes that may be affected by these ...

Estrogen and Progesterone Stimulate the Body to Make Opioids

Apr. 3, 2025 — Female hormones can suppress pain by making immune cells near the spinal cord produce opioids, a new study has found. This stops pain signals before they get to the brain. The discovery could help ...

No Bones About It: New Details About Skeletal Cell Aging Revealed

Apr. 4, 2025 — Scientists and researchers around the globe are investigating a series of mysteries about what happens to our bones over ...

Cartilage and Bone Development: Three Paths to Skeleton Formation

Mar. 27, 2025 — In vertebrates, the skeleton of different regions of the body arises from different precursor cells. Researchers have now discovered that these skeletal cells do not just differ in their ...

Are High Support Bras Bad for the Back?

Apr. 15, 2025 — Researchers uncover how over-reducing breast motion in bras could increase back pain during ...

Proteins and Pathways Involved in Inflammation Are Associated With Changes in Bone Mineral Density Over Time

Mar. 14, 2025 — Researchers have found that proteins and pathways involved in inflammation are associated with changes in bone mineral density (BMD) over time. The research, could potentially lead to the ...

Robotics and Spinal Stimulation Restore Movement in Paralysis

Mar. 12, 2025 — Scientists have developed an approach that combines rehabilitation robotics with spinal cord stimulation to restore movement in people with spinal cord injuries. The technology enhances ...

Dental Implants Still Functional After Forty Years

Mar. 3, 2025 — Dental implants used to replace single teeth continue to function well after several decades, according to a new study. After nearly forty years, all examined implants were still in place and fully ...

Innovative Animal Model for Studying Limb Spasticity

Mar. 3, 2025 — Researchers have made a significant advancement in the field of spinal cord injury research, developing a novel optogenetic mouse model that could lead to improved treatments for limb ...

Scientists Solve Mystery of How the Drug Retinoic Acid Works to Treat Neuroblastoma

Feb. 28, 2025 — Why retinoic acid is effective in this setting but not against primary tumors, has been speculated about for nearly 50 years. Scientists resolved the mystery, showing the drug 'hijacks' a ...

How Our Lungs Back Up the Bone Marrow to Make Our Blood

Feb. 27, 2025 — Red blood cells carry oxygen from the lungs to every other organ, and blood-forming stem cells must make about 200 billion new red blood cells each day to keep the oxygen flowing. For many years, ...

Novel Bone Marrow Transplant Can Cure Sickle Cell Disease, Study Suggests

Feb. 25, 2025 — A bone marrow transplant process is safe and curative for adults with sickle cell disease, according to results of a trial completed at about 20 cancer ...

Viking Skulls Reveal Severe Morbidity

Feb. 21, 2025 — Sweden's Viking Age population appears to have suffered from severe oral and maxillofacial disease, sinus and ear infections, osteoarthritis, and much more. This is shown in a study in which ...

Epidural Steroid Injections for Chronic Back Pain

Feb. 12, 2025 — Scientists have developed a new systematic review to summarize for neurologists and other clinicians the evidence for epidural steroid injections and whether they reduce pain and disability for ...

Researchers Discover New Mechanism for Male Sex Hormone

Feb. 11, 2025 — Researchers have discovered a new mechanism that is used by a male sex hormone essential for muscle and bone function. The findings could lead to the development of new drugs with fewer side effects, ...

When Blood Cancer Starts to Spread

Feb. 10, 2025 — When blood cancer cells break through the bone and multiply, tumor cells become dangerously diverse and the immune response in the region changes, researchers report. The detailed insights into ...

Drug May Counteract Muscle Loss and Osteoporosis After Rapid Weight Loss

Feb. 10, 2025 — Rapid weight loss affects muscle mass and can increase the risk of osteoporosis. But now there is good news for people taking weight loss medication who may be at risk. A new study indicates that the ...

Spinal Cord Stimulation Restores Neural Function, Targets Key Feature of Progressive Neurodegenerative Disease

Feb. 5, 2025 — Boosting communication between the spinal nerves and the muscles using the spinal cord stimulation reverses spinal muscle atrophy (SMA) progression and could be applied to other motoneuron diseases, ...

An Injectable Hydrogel for Local Bone Densification

Jan. 28, 2025 — Researchers have combined injections of a novel hydrogel with systemic osteoporosis drugs in rats, achieving rapid local increases in bone density. The results offer hope for future fracture ...

mRNA-Activated Blood Clots Could Cushion the Blow of Osteoarthritis

Jan. 22, 2025 — Following the lead of previous work on mRNA-based vaccines, therapies for spinal cord injuries and more, the method relies upon mineral-coated microparticles to deliver mRNA that encodes for ...

Novel Molecular Insights Into Bone Remodeling

Jan. 21, 2025 — The discovery of a family with sequence similarity 102 member A (Fam102a) protein as a novel bone remodeling factor that regulates both osteoclast and osteoblast differentiation can aid the ...

New Innovative Local Treatment for Osteolytic Bone Disease in Multiple Myeloma

Jan. 14, 2025 — A team of researchers has developed a new biomaterial with high potential in in the treatment of bone lesions or minimal residual disease in multiple myeloma patients. The findings showcase a ...

Overcoming Spasticity to Help Paraplegics Walk Again

Jan. 8, 2025 — Thanks to new high-frequency electrical stimulation that blocks spasticity, two paralyzed patients suffering from muscle stiffness after spinal cord injury benefit from rehabilitation protocols for ...

Achieving Bone Regeneration and Adhesion With Harmless Visible Light

Dec. 31, 2024 — A team develops an innovative injectable hydrogel for bone regeneration, addressing the limitations of traditional bone grafts and adhesion ...