Bone and Spine News

March 27, 2025

Top Headlines

Proteins and Pathways Involved in Inflammation Are Associated With Changes in Bone Mineral Density Over Time

Mar. 14, 2025 — Researchers have found that proteins and pathways involved in inflammation are associated with changes in bone mineral density (BMD) over time. The research, could potentially lead to the ...

Robotics and Spinal Stimulation Restore Movement in Paralysis

Mar. 12, 2025 — Scientists have developed an approach that combines rehabilitation robotics with spinal cord stimulation to restore movement in people with spinal cord injuries. The technology enhances rehabilitation and enables activities like cycling and walking ...

Dental Implants Still Functional After Forty Years

Mar. 3, 2025 — Dental implants used to replace single teeth continue to function well after several decades, according to a new study. After nearly forty years, all examined implants were still in place and fully ...

Innovative Animal Model for Studying Limb Spasticity

Mar. 3, 2025 — Researchers have made a significant advancement in the field of spinal cord injury research, developing a novel optogenetic mouse model that could lead to improved treatments for limb ...

Latest Headlines

updated 9:54am EDT

How Our Lungs Back Up the Bone Marrow to Make Our Blood

Feb. 27, 2025 — Red blood cells carry oxygen from the lungs to every other organ, and blood-forming stem cells must make about 200 billion new red blood cells each day to keep the oxygen flowing. For many years, ...

Scientists Solve Mystery of How the Drug Retinoic Acid Works to Treat Neuroblastoma

Feb. 28, 2025 — Why retinoic acid is effective in this setting but not against primary tumors, has been speculated about for nearly 50 years. Scientists resolved the ...

Novel Bone Marrow Transplant Can Cure Sickle Cell Disease, Study Suggests

Feb. 25, 2025 — A bone marrow transplant process is safe and curative for adults with sickle cell disease, according to results of a trial completed at about 20 cancer ...

Viking Skulls Reveal Severe Morbidity

Feb. 21, 2025 — Sweden's Viking Age population appears to have suffered from severe oral and maxillofacial disease, sinus and ear infections, osteoarthritis, and much more. This is shown in a study in which Viking ...

Epidural Steroid Injections for Chronic Back Pain

Feb. 12, 2025 — Scientists have developed a new systematic review to summarize for neurologists and other clinicians the evidence for epidural steroid injections and whether they reduce pain and disability for ...

When Blood Cancer Starts to Spread

Feb. 10, 2025 — When blood cancer cells break through the bone and multiply, tumor cells become dangerously diverse and the immune response in the region changes, researchers report. The detailed insights into ...

Researchers Discover New Mechanism for Male Sex Hormone

Feb. 11, 2025 — Researchers have discovered a new mechanism that is used by a male sex hormone essential for muscle and bone function. The findings could lead to the development of new drugs with fewer side effects, ...

Drug May Counteract Muscle Loss and Osteoporosis After Rapid Weight Loss

Feb. 10, 2025 — Rapid weight loss affects muscle mass and can increase the risk of osteoporosis. But now there is good news for people taking weight loss medication who may be at risk. A new study indicates that the ...

Novel Molecular Insights Into Bone Remodeling

Jan. 21, 2025 — The discovery of a family with sequence similarity 102 member A (Fam102a) protein as a novel bone remodeling factor that regulates both osteoclast and osteoblast differentiation can aid the ...

Spinal Cord Stimulation Restores Neural Function, Targets Key Feature of Progressive Neurodegenerative Disease

Feb. 5, 2025 — Boosting communication between the spinal nerves and the muscles using the spinal cord stimulation reverses spinal muscle atrophy (SMA) progression ...

An Injectable Hydrogel for Local Bone Densification

Jan. 28, 2025 — Researchers have combined injections of a novel hydrogel with systemic osteoporosis drugs in rats, achieving rapid local increases in bone density. The results offer hope for future fracture ...

mRNA-Activated Blood Clots Could Cushion the Blow of Osteoarthritis

Jan. 22, 2025 — Following the lead of previous work on mRNA-based vaccines, therapies for spinal cord injuries and more, the method relies upon mineral-coated microparticles to deliver mRNA that encodes for ...

New Innovative Local Treatment for Osteolytic Bone Disease in Multiple Myeloma

Jan. 14, 2025 — A team of researchers has developed a new biomaterial with high potential in in the treatment of bone lesions or minimal residual disease in multiple myeloma patients. The findings showcase a ...

Overcoming Spasticity to Help Paraplegics Walk Again

Jan. 8, 2025 — Thanks to new high-frequency electrical stimulation that blocks spasticity, two paralyzed patients suffering from muscle stiffness after spinal cord injury benefit from rehabilitation protocols for ...

Achieving Bone Regeneration and Adhesion With Harmless Visible Light

Dec. 31, 2024 — A team develops an innovative injectable hydrogel for bone regeneration, addressing the limitations of traditional bone grafts and adhesion ...

Brain Map Clarifies Neuronal Connectivity Behind Motor Function

Dec. 23, 2024 — Scientists traced connectivity between neurons to identify how the brain communicates with the spinal cord to control motor ...

Antibody That Neutralizes Inhibitory Factors Involved in Nerve Regeneration Leads to Enhanced Motor Function After Acute Spinal Cord Injury

Dec. 19, 2024 — Antibodies can improve the rehabilitation of people with acute spinal cord injury. Researchers have investigated this with promising results. For the first time, it was possible to identify patient ...

Building a Backbone: Scientists Recreate the Body's 'GPS System' in the Lab

Dec. 18, 2024 — Scientists have generated human stem cell models which contain notochord -- a tissue in the developing embryo that acts like a navigation system, directing cells where to build the spine and nervous ...

Neural Stem Cell Transplantation Shows Promise for Treating Chronic Spinal Cord Injury

Dec. 17, 2024 — Using neural stem cells could help treat spinal injuries once thought to be untreatable -- a new phase 1 trial has determined this approach is ...

How Breast Cancer Cells Survive in Bone Marrow After Remission

Dec. 4, 2024 — A new study has shed light on a previously poorly understood aspect of breast cancer recurrence: how cancer cells survive in bone marrow despite targeted ...

Scientists Develop Coral-Inspired Material to Revolutionize Bone Repair

Dec. 4, 2024 — Researchers have developed a revolutionary bone graft substitute inspired by coral which not only promotes faster healing but dissolves naturally in the body after the repair is ...

Brain Scan Predicts Effectiveness of Spinal Cord Surgery

Dec. 3, 2024 — A 10-minute brain scan can predict the effectiveness of a risky spinal surgery to alleviate intractable pain. The result gives doctors a much-needed biomarker to discuss with patients considering ...

Researchers Develop Tools to Examine Neighborhood Economic Effects on Spinal Cord Injury Outcomes

Nov. 25, 2024 — A new study emphasizes that neighborhood conditions significantly shape recovery opportunities for individuals with SCI and advocates for environmental interventions to reduce health ...

Promising Daily Tablet Increases Growth in Children With Dwarfism

Nov. 18, 2024 — A promising daily tablet is effective at increasing height and improving proportional limb growth in children with achondroplasia, the most common form of dwarfism, according to a new study. And the ...

Researchers Uncover Potential Treatment for Rare Genetic Disorders

Nov. 15, 2024 — Researchers have identified a potential treatment for Sandhoff and Tay-Sachs diseases -- two rare, often fatal lysosomal storage disorders that cause progressive damage to nerve cells in the brain ...

Scientists Discover 'Entirely Unanticipated' Role of Protein Netrin1 in Spinal Cord Development

Nov. 14, 2024 — Researchers have uncovered a surprising new role for netrin1, a crucial protein in neural development, as a regulator that limits bone morphogenetic protein signaling in the developing spinal ...

Researchers Develop Minimally Invasive Neural Interface in Revolutionary Study

Nov. 13, 2024 — A team of researchers has developed a technique for diagnosing, managing and treating neurological disorders with minimal surgical ...

Neuropathic Pain Drugs Found to Increase Risk of Hip Fracture in Older Adults

Nov. 13, 2024 — A new study by medicine safety experts found the use of gabapentinoids -- medicines widely used to treat neuropathic pain -- increased the risk of hip fractures, especially in older patients who were ...

Vitamin D During Pregnancy Boosts Children's Bone Health Even at Age Seven

Nov. 6, 2024 — Children whose mothers took extra vitamin D during pregnancy continue to have stronger bones at age seven, according to ...

Two Key Genes Identified Linking Rheumatoid Arthritis and Osteoporosis

Nov. 5, 2024 — Researchers employed analysis tools and machine learning algorithms to identify two genes linked to rheumatoid arthritis and osteoporosis that could serve as diagnostic tools and potential targets ...