Pancreatic Cancer News

April 17, 2025

Top Headlines

Key to the High Aggressiveness of Pancreatic Cancer Identified

Apr. 15, 2025 — A study demonstrates the role of the Galectin-1 protein in the nucleus of the cells surrounding the tumor -- fibroblasts -- contributing to their activation. Activated fibroblasts promote tumor growth and spread, while also conferring resistance to ...

'Sugar' Signatures Help Identify and Classify Pancreatic Cancer Cell Subtypes

Apr. 9, 2025 — Scientists have developed a new method for identifying and classifying pancreatic cancer cell subtypes based on sugars found on the outside of cancer cells. These sugars, called glycans, help cells ...

Targeted New Approach to Treat Pancreatic Cancer

Apr. 8, 2025 — Researchers have identified a new molecular target for treating pancreatic cancer. Scientists focused on transcription-replication conflicts (TRCs), which occur when the mechanisms responsible for gene expression and genome duplication collide. The ...

Pancreatic Cells 'Remember' Epigenetic Precancerous Marks Without Genetic Sequence Mutations

Apr. 4, 2025 — Scientists say they have found a pattern of so-called epigenetic 'marks' in a transition state between normal and pancreatic cancer cells in mice, and that the normal cells may keep at least a ...

Latest Headlines

updated 10:45pm EDT

In Pancreatic Cancer, a Race Against Time

Apr. 2, 2025 — Scientists have found a way to 'intercept' pancreatic cancer. By inhibiting the cancer gene FGFR2, they were able to slow tumor formation. By targeting the FGFR2 and EGFR proteins, they were able to ...

Immunotherapy May Boost KRAS-Targeted Therapy in Pancreatic Cancer

Mar. 14, 2025 — Adding immunotherapy to new KRAS inhibitors boosted responses in preclinical models, setting the stage for future trials of the combination ...

Chronic Stress and Obesity Work Together to Accelerate Pancreatic Cancer Development and Growth, Study Finds

Mar. 10, 2025 — A new study suggests that chronic stress and an unhealthy diet may work together to fuel the early development of pancreatic cancer, shedding light ...

Toward Improved Early Detection of Pancreatic Cancer

Feb. 18, 2025 — Pancreatic cancer (PC) is the worst prognosis cancer globally, with just 13% of patients who are diagnosed with PC surviving for 5 years or more after initial diagnosis. Early detection of PC is the ...

New Blood Test Identifies Hard-to-Detect Pancreatic Cancer With 85% Accuracy

Feb. 12, 2025 — A new blood test could help doctors detect pancreatic cancer earlier, potentially improving survival rates for one of the deadliest ...

Pancreatic Cancer Immune Map Provides Clues for Precision Treatment Targeting

Feb. 7, 2025 — Pancreatic cancer patients may benefit from future precision treatments as a new study shows how some tumors may potentially be more susceptible to ...

How Hungry Fat Cells Could Someday Starve Cancer to Death

Feb. 4, 2025 — Liposuction and plastic surgery aren't often mentioned in the same breath as cancer. But they are the inspiration for a new approach to treating cancer that uses engineered fat cells to deprive ...

Scientists Want to Throw a Wrench in the Gears of Cancer's Growth

Feb. 4, 2025 — For decades, scientists have tried to stop cancer by disabling the mutated proteins that are found in tumors. But many cancers manage to overcome this and continue growing. Now, scientists think they ...

Cancer Mortality Continues to Drop Despite Rising Incidence in Women

Jan. 16, 2025 — The American Cancer Society (ACS) today released Cancer Statistics, 2025, the organization's annual report on cancer facts and trends. The new findings show the cancer mortality rate declined by 34% ...

Experimental Blood Test for Pancreatic Cancer Undergoing Clinical Development and Evaluation

Jan. 13, 2025 — An experimental blood test for pancreatic cancer is being evaluated by a commercial laboratory, an important milestone toward making the test ...

Lighting Up Cancer Cells With Biolasers

Jan. 6, 2025 — Researchers have developed a way of detecting circulating tumor cells in the bloodstream of pancreatic cancer and lung cancer ...

Enzyme Promoting Tumor Growth and Spread in Pancreatic Cancer Identified

Jan. 2, 2025 — An enzyme called MICAL2 promotes tumor growth and metastasis in the most common form of pancreatic cancer, according to a new ...

AI-Based Tool for Pancreatic Cancer Diagnostics

Dec. 12, 2024 — Researchers have successfully developed a deep learning model that classifies pancreatic ductal adenocarcinoma (PDAC), the most common form of pancreatic cancer, into molecular subtypes using ...

Organoids Represent the Complex Cell Landscape of Pancreatic Cancer

Dec. 11, 2024 — Researchers have grown tumor organoids -- three-dimensional miniature tumors in the laboratory -- that mimic the different structures and characteristics of pancreatic cancer. The scientists ...

Engineered Immune Cells May Be Able to Tame Inflammation

Dec. 5, 2024 — When the immune system overreacts and starts attacking the body, the only option may be to shut the entire system down and risk developing infections or ...

Researchers Create a New Organoid With All Key Pancreas Cells

Dec. 2, 2024 — Researchers have developed a new organoid that mimics the human fetal pancreas, offering a clearer view of its early development. The researchers were able to recreate a complete structure that ...

Protein Degradation Strategy Offers New Hope in Cancer Therapy

Nov. 11, 2024 — A team of scientists has used a novel approach to identify protein degraders that target Pin1, a protein involved in pancreatic cancer ...

Researchers Uncover New Role of Mutant Proteins in Some of the Deadliest Cancers

Nov. 11, 2024 — Researchers have discovered a new way in which RAS genes, which are commonly mutated in cancer, may drive tumor growth beyond their well-known role in signaling at the cell surface. Mutant RAS, they ...

Insights Into KRAS Mutations in Pancreatic Cancers

Oct. 2, 2024 — A common mutation in the KRAS gene is associated with improved overall survival in pancreatic ductal adenocarcinoma (PDAC) compared with other variants, in part because the mutation appears to lead ...

New Cancer Diagnoses Did Not Rebound as Expected Following Pandemic

Sep. 24, 2024 — Cancer incidence trends in 2021 largely returned to what they were before the COVID-19 pandemic, according to a study by researchers at the National Institutes of Health (NIH). However, there was ...

How the Immune System Fails as Cancer Arises

Sep. 12, 2024 — Scientists discovered a targetable molecule that reprograms immune cells and turns them into cancer ...

Pancreatic Cancer: Study Finds Most Early Staging Inaccurate

Sep. 5, 2024 — Staging of patients with early pancreatic cancer is inaccurate as much as 80% of the time, according to a new study. The finding underscores the urgent need for advancements in diagnostic technology ...

Insulin Cells Don't Need to Team Up

Sep. 3, 2024 — Our glycaemic balance is based on the ability of the pancreatic beta cells to detect glucose and secrete insulin to maintain our blood sugar levels. If these cells malfunction, the balance is broken, ...

New Pancreatic Cancer Treatment Proves Effective in Shrinking, Clearing Tumors

Aug. 28, 2024 — Researchers have demonstrated in mice a new method to combat pancreatic cancer. The study outlines the synergistic effects of a novel nanoparticle drug-delivery system to activate an immune pathway ...

Old Chemo Drug, New Pancreatic Cancer Therapy?

Aug. 26, 2024 — Researchers discovered that treating pancreatic cancer with a common chemotherapy drug makes immunotherapy more effective. Folinic acid elevates levels of two anti-cancer immune molecules within ...

New Anti-CKAP4 Antibodies Deliver Hope for Pancreatic Cancer Treatment

Aug. 22, 2024 — Researchers have developed an antibody that prevents the activation of the Dickkopf 1-Cytoskeleton-associated protein 4 (DKK1-CKAP4) pathway, which is important for tumor growth in several cancers, ...

A Ketogenic Diet Could Improve the Response to Pancreatic Cancer Therapy

Aug. 14, 2024 — Scientists have discovered a way to get rid of pancreatic cancer in mice by putting them on a high fat, or ketogenic, diet and giving them cancer ...

Faster Detection of Pancreatic Cancer

Aug. 9, 2024 — Pancreatic cancer is one of the most lethal forms of cancer, primarily because it is usually diagnosed very late. Current markers are too insensitive and unspecific for early detection screenings. A ...

Discovery Suggests Opportunity to Improve Effectiveness of KRAS Inhibitors Against Pancreatic Cancer

July 11, 2024 — Researchers discovered a new mechanism of resistance to KRAS inhibitors that suggests an opportunity to make the treatment more ...

AI Model to Improve Patient Response to Cancer Therapy

July 3, 2024 — A new artificial intelligence tool that can help to select the most suitable treatment for cancer patients has been ...