Pharmaceuticals News

January 30, 2025

Top Headlines

Study Finds Three New Safe, Effective Ways to Treat Drug-Resistant Tuberculosis

Jan. 29, 2025 — Study finds three new safe and effective drug regimens to fight multidrug-resistant TB. The treatments, which include recently discovered TB drugs, give new options for shorter, personalized ...

An Injectable Hydrogel for Local Bone Densification

Jan. 28, 2025 — Researchers have combined injections of a novel hydrogel with systemic osteoporosis drugs in rats, achieving rapid local increases in bone density. The results offer hope for future fracture prevention therapies in osteoporosis ...

Genetic 'Fingerprint' to Predict Drug Resistance in Bacteria

Jan. 28, 2025 — New research has identified a unique genetic signature in bacteria that can predict their likelihood of developing antibiotic resistance, a finding that can help quickly identify precision-based treatments that are more effective against the deadly, ...

New Drug Shows Promise in Restoring Vision for People With Nerve Damage

Jan. 24, 2025 — Researchers have found a promising drug candidate that could help restore vision in individuals with multiple sclerosis (MS) and other neurological conditions that damage ...

Latest Headlines

updated 8:42am EST

Scientists Design Peptides to Enhance Drug Efficacy

Jan. 24, 2025 — Scientists have developed a groundbreaking approach using specially designed peptides to improve drug formulations. This innovative method significantly enhances anti-tumor ...

Fewer Than 1% of U.S. Clinical Drug Trials Enroll Pregnant Participants, Study Finds

Jan. 21, 2025 — A new study found that pregnant women are regularly excluded from clinical drug trials that test for safety, raising concerns for the efficacy of ...

Curiosity Driven Experiment Helps Unravel Antibiotic-Resistance Mystery

Jan. 23, 2025 — An international collaboration has achieved an important breakthrough in understanding the genetic mechanisms that allow bacteria to build resistance to ...

Antibiotics, Vaccinations and Anti-Inflammatory Medication Linked to Reduced Risk of Dementia

Jan. 21, 2025 — Antibiotics, antivirals, vaccinations and anti-inflammatory medication are associated with reduced risk of dementia, according to new research that ...

Treatment for Children With Obesity Has Lasting Effect

Jan. 21, 2025 — When children with obesity undergo weight-loss treatment, the effects have repercussions later in life and the risk of serious health problems and premature death is lower as they reach young ...

A Deep Learning Pipeline for Controlling Protein Interactions

Jan. 16, 2025 — Scientists have used deep learning to design new proteins that bind to complexes involving other small molecules like hormones or drugs, opening up a world of possibilities in the computational ...

Antibiotic Treatment for Drug-Resistant Tuberculosis Found to Be Safe and Effective in Clinical Trial

Jan. 15, 2025 — Sydney researchers have found that Levofloxacin substantially reduces risk of drug-resistant tuberculosis. This discovery offers new hope against a ...

Chemists Unlock the Potential of Ketone and Ester Molecules, Paving the Way for Greener and More Efficient Drug Development

Jan. 9, 2025 — Scientists have long considered ketones (a fundamental chemical class) and esters (molecules formed when an acid reacts with an alcohol) to be locked ...

A Molecule Is Shown to Produce Cognitive Improvement in Rodents With Early Alzheimer's Disease

Jan. 15, 2025 — Scientists have come up with a drug that is a potential candidate for tackling memory deficits in the early stages of the disease in rodents. ...

New Innovative Local Treatment for Osteolytic Bone Disease in Multiple Myeloma

Jan. 14, 2025 — A team of researchers has developed a new biomaterial with high potential in in the treatment of bone lesions or minimal residual disease in multiple ...

Tongue Cancer Organoids Reveal Secrets of Chemotherapy Resistance

Jan. 9, 2025 — Tongue cancer (TC) cells can enter a chemo-resistant state by activating pathways related to autophagy and cholesterol synthesis, report researchers. Using a large-scale library of TC organoids they ...

Ketamine Use on the Rise in U.S. Adults; New Trends Emerge

Jan. 7, 2025 — According to a new study, ketamine use has risen significantly since 2015. The results highlight the need for closer monitoring of recreational ketamine ...

Overcoming Resistance: Researchers Find New Utility for Old Antibiotics

Jan. 6, 2025 — Researchers at discovered a critical vulnerability in drug-resistant bacteria: zinc -- or a lack ...

Tuberculosis Strains Resistant to New Drugs Are Transmitted Between Patients

Jan. 6, 2025 — Tuberculosis (TB) is the world's biggest infectious disease killer with multidrug-resistant TB (MDR-TB) posing a particular threat to global health. A study shows that resistance to the new ...

New Biomarkers Could Improve Early Detection and Monitoring of Kidney Injury

Jan. 6, 2025 — Researchers have identified six new biomarkers that could detect kidney injury faster and with more sensitivity, advancing safer drug development and improving health outcomes for patients. The new ...

Research on Clozapine Safety: Big-Data Evidence on Rare Blood Cancer Cases

Jan. 2, 2025 — An inter-departmental research team has conducted an analytic real-world cohort study on the association of clozapine, a highly efficacious antipsychotic drug, with the incidence of blood cancer. ...

Discovery Links Cellular Structures to Kidney Cancer Treatment Outcomes

Jan. 2, 2025 — Fighting cancer can seem like a deadly game of chance. While some patients may respond well to certain treatments, others might not be as fortunate. Doctors and scientists have long struggled to ...

Cancer-Preventing Topical Immunotherapy Trains the Immune System to Fight Pre-Cancers

Jan. 2, 2025 — A new study uncovers how a novel immunotherapy prevents squamous cell carcinoma, with benefits lasting five years after treatment. This therapy is the first to activate specific components of the ...

New Drug to Prevent Migraine May Start Working Right Away

Dec. 23, 2024 — A drug recently approved to prevent migraine may start working right away, according to a new study. The study looked at the drug atogepant, which is a calcitonin gene-related peptide (CGRP) receptor ...

Researchers Develop Tool to Fast-Track Measurement of Protein Interactions for Drug Discovery

Dec. 23, 2024 — Researchers have created a platform, called SIMPL2, that revolutionizes the study of protein-protein interactions by simplifying detection while improving measurement accuracy. While protein-protein ...

Research Points the Way to Lifesaving Antiparasitic Drugs While Unlocking a Scientific Mystery

Dec. 20, 2024 — A breakthrough in understanding how a single-cell parasite makes ergosterol (its version of cholesterol) could lead to more effective drugs for human leishmaniasis, a parasitic disease that afflicts ...

New Molecule-Creation Method a 'Powerful Tool' to Accelerate Drug Synthesis and Discovery

Dec. 19, 2024 — A team of chemists has unveiled a novel method to simplify the synthesis of piperidines, a key structural component in many pharmaceuticals. The study combines biocatalytic carbon-hydrogen oxidation ...

First Successful Clinical Trial of VU319 Brings Alzheimer's Treatment One Step Closer

Dec. 19, 2024 — Phase I clinical trial of a drug was successfully completed, with promise to treat Alzheimer's and other neurodegenerative diseases. The compound, named VU319, is the first end-to-end drug ...

What Is Metformin's Secret Sauce?

Dec. 18, 2024 — Until now, scientists have been unable to determine how metformin, a Type 2 diabetes medication that lowers blood sugar, works. A study provided direct evidence in mice that it reversibly cuts the ...

Nano Drug Delivery System Heralds Safer Era for Drug Development

Dec. 17, 2024 — A team of researchers has created an innovative drug delivery system with outstanding potential to improve drug ...

Scientists Develop Scans That Light-Up Aggressive Cancer Tumors for Better Treatment

Dec. 17, 2024 — Researchers have used a chemical compound to light up treatment-resistant cancers on imaging scans, in a breakthrough that could help medical professionals better target and treat ...

New Drug Shows Promise Against Duchenne Muscular Dystrophy

Dec. 16, 2024 — A novel drug holds promise for treating Duchenne muscular dystrophy (DMD), a rare genetic disorder that causes severe muscle degeneration. Researchers have discovered that an experimental compound ...

From Yemen to Mayotte, the Spread of a Highly Drug-Resistant Cholera Strain

Dec. 13, 2024 — Scientists have revealed the spread of a highly drug-resistant cholera ...

Combined Screening Can Detect Liver Damage in Diabetes Patients

Dec. 13, 2024 — New research highlights the possibility of screening people with type 2 diabetes for liver damage at the same time as they undergo screening for eye ...

How This Cancer Drug Could Make Radiation a Slam Dunk Therapy

Dec. 10, 2024 — Radiation is one of the most effective ways to kill a tumor. But these therapies are indiscriminate, and they can damage healthy ...