Pharmaceuticals News

December 28, 2024

Top Headlines

New Drug to Prevent Migraine May Start Working Right Away

Dec. 23, 2024 — A drug recently approved to prevent migraine may start working right away, according to a new study. The study looked at the drug atogepant, which is a calcitonin gene-related peptide (CGRP) receptor antagonist taken by ...

Research Points the Way to Lifesaving Antiparasitic Drugs While Unlocking a Scientific Mystery

Dec. 20, 2024 — A breakthrough in understanding how a single-cell parasite makes ergosterol (its version of cholesterol) could lead to more effective drugs for human leishmaniasis, a parasitic disease that afflicts ...

New Molecule-Creation Method a 'Powerful Tool' to Accelerate Drug Synthesis and Discovery

Dec. 19, 2024 — A team of chemists has unveiled a novel method to simplify the synthesis of piperidines, a key structural component in many pharmaceuticals. The study combines biocatalytic carbon-hydrogen oxidation ...

First Successful Clinical Trial of VU319 Brings Alzheimer's Treatment One Step Closer

Dec. 19, 2024 — Phase I clinical trial of a drug was successfully completed, with promise to treat Alzheimer's and other neurodegenerative diseases. The compound, named VU319, is the first end-to-end drug discovery ...

Latest Headlines

updated 10:42pm EST

Researchers Develop Tool to Fast-Track Measurement of Protein Interactions for Drug Discovery

Dec. 23, 2024 — Researchers have created a platform, called SIMPL2, that revolutionizes the study of protein-protein interactions by simplifying detection while ...

What Is Metformin's Secret Sauce?

Dec. 18, 2024 — Until now, scientists have been unable to determine how metformin, a Type 2 diabetes medication that lowers blood sugar, works. A study provided direct evidence in mice that it reversibly cuts the ...

Scientists Develop Scans That Light-Up Aggressive Cancer Tumors for Better Treatment

Dec. 17, 2024 — Researchers have used a chemical compound to light up treatment-resistant cancers on imaging scans, in a breakthrough that could help medical ...

Nano Drug Delivery System Heralds Safer Era for Drug Development

Dec. 17, 2024 — A team of researchers has created an innovative drug delivery system with outstanding potential to improve drug ...

New Drug Shows Promise Against Duchenne Muscular Dystrophy

Dec. 16, 2024 — A novel drug holds promise for treating Duchenne muscular dystrophy (DMD), a rare genetic disorder that causes severe muscle degeneration. Researchers have discovered that an experimental compound ...

Combined Screening Can Detect Liver Damage in Diabetes Patients

Dec. 13, 2024 — New research highlights the possibility of screening people with type 2 diabetes for liver damage at the same time as they undergo screening for eye ...

From Yemen to Mayotte, the Spread of a Highly Drug-Resistant Cholera Strain

Dec. 13, 2024 — Scientists have revealed the spread of a highly drug-resistant cholera ...

How This Cancer Drug Could Make Radiation a Slam Dunk Therapy

Dec. 10, 2024 — Radiation is one of the most effective ways to kill a tumor. But these therapies are indiscriminate, and they can damage healthy ...

A New Approach to Predicting Malaria Drug Resistance

Nov. 28, 2024 — Researchers analyzed the genomes of hundreds of malaria parasites to determine which genetic variants are most likely to confer drug ...

Antipsychotic Medications Don't Always Work the Way They're Supposed to

Dec. 5, 2024 — A study analyzed data from nearly 500,000 Canadian patients who lived in nursing homes across Canada between 2000 and 2022. It found that residents who were given antipsychotic medications showed a ...

Network-Based Analyses Uncover How Neuroinflammation-Causing Microglia in Alzheimer's Disease Form

Dec. 6, 2024 — Researchers have unraveled how immune cells called microglia can transform and drive harmful processes like neuroinflammation in Alzheimer's disease. The study also integrates drug databases ...

Genetic Data from 'Biobanks' May Help Improve Prediction of Effectiveness, Side Effects of Common Medications

Dec. 4, 2024 — A new study has outlined a new framework that researchers say would improve predictive power of genetics to determine how well a patient would respond to commonly prescribed medications as well as ...

Gluing Treatment to Cancer

Dec. 3, 2024 — Treatment for more advanced and difficult-to-treat head and neck cancers can be improved with the addition of polyvinyl alcohol (PVA), the same ingredient used in children's glue. Researchers ...

Bacteria Ditch Tags to Dodge Antibiotics

Nov. 29, 2024 — Bacteria modify their ribosomes when exposed to widely used antibiotics, according to new research. The modified ribosomes have changes specifically in the regions where antibiotics latch on to and ...

Tirzepatide Shows Powerful Diabetes-Prevention Effect in Three-Year Trial

Nov. 26, 2024 — Tirzepatide, a new injectable weight-loss drug, reduced the risk of diabetes in patients with obesity and prediabetes by more than 90% over a three-year period, compared with placebo, according to ...

Scientists Find Why Tamoxifen Works Better for Some People

Nov. 25, 2024 — Tamoxifen is a common and important treatment to prevent breast cancer from recurring. A new study shows that variation in a patient's gut microbiome can impact how effective the treatment ...

From Food Crops to Cancer Clinics: Lessons in Extermination Resistance

Nov. 21, 2024 — Researchers explore how established agricultural pest management strategies could be adapted to address cancer therapy. The pioneering method opens new possibilities for controlling drug resistance ...

Parkinson's Drug Changes the Gut Microbiome for the Worse Due to Iron Deficiency

Nov. 21, 2024 — In a groundbreaking new study scientists have revealed that the widely prescribed Parkinson's disease drug entacapone significantly disrupts the human gut microbiome by inducing iron deficiency. ...

New Hope for Diabetic Heart Disease Treatment

Nov. 21, 2024 — Drug discovery researchers have found that a natural fat molecule called 'lipoxin A4' (LXA4) could significantly reduce inflammation and improve function for diabetic ...

Weight-Loss Drug Reduces Risk of Early Death for Patients With Heart Failure, Trial Finds

Nov. 20, 2024 — Weight-loss and diabetes drug tirzepatide can reduce the risk of death or worsening heart failure for patients with obesity and heart failure with preserved pump function, new research ...

Trial Shows Alcohol-Mimicking Medication Can Give Laryngeal Dystonia Patients Back Their Voice

Nov. 20, 2024 — Researchers have led a clinical trial of a drug that mimics the effects of alcohol in more than 100 patients with laryngeal dystonia, a neurological condition that causes involuntary muscle spasms in ...

A Bioinspired Capsule Can Pump Drugs Directly Into the Walls of the GI Tract

Nov. 20, 2024 — Inspired by the jets of water that squids use to propel themselves through the ocean, a team developed an ingestible capsule that releases a burst of drugs directly into the lining of the stomach or ...

Probiotic Delivers Anticancer Drug to the Gut

Nov. 20, 2024 — Researchers shrink gastrointestinal tumors in mice using a yeast probiotic to deliver immunotherapy to the gut, offering a potentially novel strategy to target hard-to-reach gut ...

First Molecule Identified That Promotes Gut Healing While Inhibiting Tumour Progression

Nov. 20, 2024 — Researchers found a molecule that can both help the intestines to heal after damage and suppress tumour growth in colorectal cancer. The discovery could lead to new treatments for inflammatory bowel ...

Cardiovascular Drugs May Reduce Dementia Risk

Nov. 19, 2024 — Common cardiovascular drugs are linked to a lower risk of dementia in older age, according to a new ...

Eradivir's EV25 Therapeutic Reduces Advanced-Stage Influenza Viral Loads Faster, More Thoroughly in Preclinical Studies Than Current Therapies

Nov. 19, 2024 — A research article shows that Eradivir's patent-pending antiviral therapeutic called EV25 reduces lung viral loads of advanced-stage influenza in preclinical studies quicker and more effectively ...

Promising Daily Tablet Increases Growth in Children With Dwarfism

Nov. 18, 2024 — A promising daily tablet is effective at increasing height and improving proportional limb growth in children with achondroplasia, the most common form of dwarfism, according to a new study. And the ...

Multiple Sclerosis Drug May Help With Poor Working Memory

Nov. 18, 2024 — Fampridine is currently used to improve walking ability in multiple sclerosis. A new study shows that it could also help individuals with reduced working memory, as seen in mental health conditions ...

Achilles Heel of Antibiotic-Resistant Bacteria

Nov. 16, 2024 — To stem the surging antibiotic resistance public health crisis, scientists seek solutions inside the mechanics of bacterial infection. A new study has found a vulnerability related to magnesium ...

Children Exposed to Antiseizure Meds During Pregnancy Face Neurodevelopmental Risks, Study Finds

Nov. 15, 2024 — Children born to mothers who take antiseizure medications to manage seizures and psychiatric conditions during pregnancy may face increased risks of neurodevelopmental conditions, according to new ...