Pharmaceuticals News

March 2, 2025

Top Headlines

Reactive Nitrogen Species Dominance Is Key in the Fight Against Antimicrobial Resistance

Feb. 27, 2025 — The balance between two types of molecules -- reactive nitrogen species (RNS) and reactive oxygen species (ROS) -- plays a crucial role in tackling drug-resistant bacteria, according to a new ...

Why Brain Cancer Is Often Resistant to Immunotherapy

Feb. 26, 2025 — New findings could help make immunotherapies for brain cancer more effective. The team analyzed almost 200,000 individual immune cells in tumor samples taken from patients with glioma, the most common and aggressive type of primary brain cancer. The ...

New Method Searches Through 10 Sextillion Drug Molecules

Feb. 26, 2025 — A recent study shows that computer algorithms can be used to find molecules that can be developed into anti-inflammatory drugs. In the article, the researchers also describe how the same strategy can be used to search through 10 sextillion ...

A New Drug Screening Method Could Bring a Solution to Drug Delivery and Efficacy Issues

Feb. 26, 2025 — A new method seeks specific molecules that can target desired tissues through the bloodstream and penetrate tissues by passing through cells. This innovation could help solve issues related to drug ...

Latest Headlines

updated 8:12pm EST

Drug May Prevent Some Migraine Attacks in Children and Teens

Feb. 26, 2025 — For children and teens living with migraine, there may be a new preventive treatment, according to a preliminary study. Researchers found the drug zonisamide, which has been used to treat seizures, ...

Scientists Invent New Drug Candidates to Treat Antibiotic-Resistant Bacteria

Feb. 24, 2025 — There's an arms race in medicine -- scientists design drugs to treat lethal bacterial infections, but bacteria can evolve defenses to those drugs, ...

Novel Method to Synthesize Valuable Fluorinated Drug Compounds

Feb. 21, 2025 — Researchers have pioneered a new catalytic transformation that converts epoxides into fluorinated oxetanes, a coveted but difficult-to-make class of drug molecules that escaped synthetic preparation ...

Child ADHD Risk Linked to Mother's Use of Acetaminophen

Feb. 20, 2025 — Fetal acetaminophen exposure increases the likelihood that a child will develop attention-deficit/hyperactivity disorder (ADHD), according to a new ...

Researchers Develop Novel Computational Approach for Identifying Synergistic Drug Combinations

Feb. 20, 2025 — Researchers have developed a powerful computational tool, named iDOMO, to improve the prediction of drug synergy and accelerate the development of ...

PairMap: Revolutionizing Drug Discovery With Precise Energy Calculations

Feb. 4, 2025 — Precise calculations of binding free energy are pivotal in reducing the high costs and inefficiencies of drug discovery. A recent study presents PairMap, an innovative computational tool that ...

Biologists Transform Gut Bacteria Into Tiny Protein Pharmacies

Feb. 18, 2025 — Biologists converted gut bacteria into miniature protein factories that manufacture and release a sustained flow of targeted proteins inside the lower intestines. This technique solves one of the ...

New Therapy May Effectively Control HIV in Uganda

Feb. 19, 2025 — A multi-national, multi-institutional study investigators found little natural resistance to a new HIV therapy called lenacapavir in a population of patients in ...

Mpox: Better Understanding of Tecovirimat Resistance

Feb. 12, 2025 — A virus originally found in animals, mpox -- which causes the disease of the same name -- is now circulating in humans. Since 2022, it has been the cause of major epidemics spreading outside endemic ...

Drug May Counteract Muscle Loss and Osteoporosis After Rapid Weight Loss

Feb. 10, 2025 — Rapid weight loss affects muscle mass and can increase the risk of osteoporosis. But now there is good news for people taking weight loss medication who may be at risk. A new study indicates that the ...

New Study on Drug Checking: Trend Warnings and Alerts

Feb. 10, 2025 — A new study analyses how other countries' drug checking services use and share data, as a way of helping Australia's policymakers decide what to do with ours. The researchers also spoke ...

Personalized Cancer Treatment Using 3D Bioprinting Technology

Feb. 7, 2025 — Scientists have successfully developed a gastric cancer model using 3D bioprinting technology and patient-derived cancer tissue fragments. This innovative model preserves the characteristics of ...

Essential Genome of Malaria Parasite Plasmodium Knowlesi Mapped

Feb. 6, 2025 — A new, comprehensive map of all the genes essential for blood infections in Plasmodium knowlesi (P. knowlesi), a parasite that causes malaria in humans, has been generated. The map contains the most ...

A New Way to Detect Inflammation

Feb. 6, 2025 — Nearly every disease has an inflammatory component, but blood tests can't pinpoint inflammation in specific organs or tissues in the human body. Now researchers have developed a method to detect ...

Scientists Discover New Weapon to Fight Treatment-Resistant Melanoma

Feb. 5, 2025 — Scientists identified a new strategy for attacking treatment-resistant melanoma: inhibiting the gene ...

Outside-in Signaling Shows a Route Into Cancer Cells

Feb. 4, 2025 — A new study shows how an anticancer drug triggers an 'outside in' signal that gets it sucked into a cancer cell. The work reveals a new signaling mechanism that could be exploited for ...

New Drug Shows Promise in Reversing Memory Loss for Early Alzheimer's Patients

Feb. 4, 2025 — A paradigm-shifting study shows an experimental drug, GL-II-73, has the potential to restore memory and cognitive function in a mouse model of Alzheimer's disease. The study demonstrates that ...

Computer Model Helps Identify Cancer-Fighting Immune Cells Key to Immunotherapy

Feb. 3, 2025 — Researchers have developed a computer model to help scientists identify tumor-fighting immune cells in patients with lung cancer treated with immune checkpoint ...

This Delicate Nanoflower Is Downright Deadly to Bacteria

Jan. 31, 2025 — A carnation-like nanostructure could someday be used in bandages to promote wound healing. Researchers report that laboratory tests of their nanoflower-coated dressings demonstrate antibiotic, ...

Study Finds Three New Safe, Effective Ways to Treat Drug-Resistant Tuberculosis

Jan. 29, 2025 — Study finds three new safe and effective drug regimens to fight multidrug-resistant TB. The treatments, which include recently discovered TB drugs, give new options for shorter, personalized ...

An Injectable Hydrogel for Local Bone Densification

Jan. 28, 2025 — Researchers have combined injections of a novel hydrogel with systemic osteoporosis drugs in rats, achieving rapid local increases in bone density. The results offer hope for future fracture ...

Genetic 'Fingerprint' to Predict Drug Resistance in Bacteria

Jan. 28, 2025 — New research has identified a unique genetic signature in bacteria that can predict their likelihood of developing antibiotic resistance, a finding that can help quickly identify precision-based ...

New Drug Shows Promise in Restoring Vision for People With Nerve Damage

Jan. 24, 2025 — Researchers have found a promising drug candidate that could help restore vision in individuals with multiple sclerosis (MS) and other neurological conditions that damage ...

Scientists Design Peptides to Enhance Drug Efficacy

Jan. 24, 2025 — Scientists have developed a groundbreaking approach using specially designed peptides to improve drug formulations. This innovative method significantly enhances anti-tumor ...

Curiosity Driven Experiment Helps Unravel Antibiotic-Resistance Mystery

Jan. 23, 2025 — An international collaboration has achieved an important breakthrough in understanding the genetic mechanisms that allow bacteria to build resistance to ...

Fewer Than 1% of U.S. Clinical Drug Trials Enroll Pregnant Participants, Study Finds

Jan. 21, 2025 — A new study found that pregnant women are regularly excluded from clinical drug trials that test for safety, raising concerns for the efficacy of these medications for maternal and child ...

Antibiotics, Vaccinations and Anti-Inflammatory Medication Linked to Reduced Risk of Dementia

Jan. 21, 2025 — Antibiotics, antivirals, vaccinations and anti-inflammatory medication are associated with reduced risk of dementia, according to new research that looked at health data from over 130 million ...

Treatment for Children With Obesity Has Lasting Effect

Jan. 21, 2025 — When children with obesity undergo weight-loss treatment, the effects have repercussions later in life and the risk of serious health problems and premature death is lower as they reach young ...

A Deep Learning Pipeline for Controlling Protein Interactions

Jan. 16, 2025 — Scientists have used deep learning to design new proteins that bind to complexes involving other small molecules like hormones or drugs, opening up a world of possibilities in the computational ...

Trastuzumab Emtansine Improves Long-Term Survival in HER2 Breast Cancer

Jan. 15, 2025 — In patients with high-risk HER2-positive breast cancer, post-surgery, or adjuvant, treatment with trastuzumab emtansine (T-DM1) reduced the long-term risk of death or invasive disease by 46% and ...