Crohn's Disease News

October 25, 2025

Top Headlines

MIT Discovers Amino Acid That Helps the Gut Heal Itself

Oct. 23, 2025 — MIT scientists have found that an amino acid called cysteine can help the gut heal itself. In mouse studies, a cysteine-rich diet activated immune cells that release a molecule speeding up tissue repair in the small intestine. This process helped ...

Scientists Just Found a Molecule That Could Stop Parkinson’s in Its Tracks

Oct. 8, 2025 — Researchers have designed a peptide that prevents the deadly misfolding of alpha-synuclein, the protein behind Parkinson’s and some dementias. In lab and animal tests, it stabilized the protein and ...

Cocoa Supplements Show Surprising Anti-aging Potential

Sep. 27, 2025 — Daily cocoa extract supplements reduced key inflammation markers in older adults, pointing to a role in protecting the heart. The findings reinforce the value of flavanol-rich, plant-based foods for healthier ...

Scientists Uncover How to Block Pain Without Side Effects

Sep. 26, 2025 — Scientists have discovered a way to block pain while still allowing the body’s natural healing to take place. Current painkillers like ibuprofen and aspirin often come with harmful side effects because they shut down both pain and inflammation. ...

Dementia-like Clumps Found in Cells Before Cancer Strikes

Sep. 22, 2025 — Researchers found that pancreatic pre-cancer cells mimic dementia by forming clumps of proteins due to faulty recycling processes. These insights could shed light on why pancreatic cancer develops so aggressively and why it is difficult to treat. By ...

Your Pancreas May Be Making Its Own Version of Ozempic

Sep. 21, 2025 — Duke University scientists have discovered that pancreatic alpha cells, long believed to only produce glucagon, actually generate powerful amounts of GLP-1 — the same hormone mimicked by popular diabetes drugs like semaglutide (Ozempic and ...

Smoking’s Hidden Gut Bacteria Trick May Lead to New Colitis Treatments

Sep. 19, 2025 — For decades, scientists have puzzled over why smoking makes Crohn’s disease worse but seems to protect people from ulcerative colitis. Now, researchers at RIKEN have discovered that smoking creates metabolites like hydroquinone that allow mouth ...

Powerful New Painkiller ADRIANA Shows Promise in Ending Opioid Dependence

Sep. 2, 2025 — Japanese scientists have developed ADRIANA, a non-opioid painkiller that could provide powerful relief without the dangers of addiction. With successful trials already completed, large U.S. studies are now underway, raising hopes for a safer future ...

The Pandemic’s Secret Aftershock: Inside the Gut-brain Breakdown

July 30, 2025 — A new global study reveals a striking post-pandemic surge in gut-brain disorders like IBS and functional dyspepsia. Researchers compared data from 2017 and 2023 and discovered sharp increases IBS up 28% and dyspepsia nearly 44%. Those suffering from ...

This Gut Hormone Could Explain 40% of IBS-D Cases—and Lead to a Cure

July 29, 2025 — A mysterious gut hormone may be behind many cases of chronic diarrhea, especially in people with undiagnosed bile acid malabsorption, a condition often mistaken for irritable bowel syndrome. Researchers from the University of Cambridge identified ...

Parkinson’s May Begin Decades Earlier — And Your Immune System Might Know First

June 27, 2025 — Misbehaving T cells light up long before Parkinson’s symptoms show, zeroing in on vulnerable brain proteins. Their early surge could double as an alarm bell and a target for stop-it-early ...

How Brain Cells Meant to Help May Be Making Depression Worse

June 24, 2025 — Major depressive disorder affects hundreds of millions worldwide, but a key to understanding its origins may lie in the brain’s immune system. New findings spotlight astrocytes—previously overshadowed by microglia—as major players in ...

Latest Headlines

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Exercise Might Be the Key to a Younger, Sharper Immune System

Oct. 14, 2025 — Endurance exercise may train the immune system as much as the muscles. Older adults with decades of running or cycling had immune cells that functioned better and aged more slowly. Their inflammation ...

Scientists Finally Explain the Real Reason Pregnant Women Get Morning Sickness

Sep. 29, 2025 — Morning sickness isn’t just random misery—it’s a biological defense system shaped by evolution to protect the fetus. By linking immune ...

Preventing Chronic Inflammation from Turning Into Cancer

June 2, 2025 — Chronic inflammatory bowel disease is challenging to treat and carries a risk of complications, including the development of bowel cancer. Young people are particularly affected: when genetic ...

Combination Therapy Can Prolong Life in Severe Heart Disease

June 2, 2025 — Aortic valve narrowing (aortic stenosis) with concomitant cardiac amyloidosis is a severe heart disease of old age that is associated with a high risk of death. Until now, treatment has consisted of ...

Zika Virus Uses Cells' 'Self-Care' System to Turn Against Host

May 27, 2025 — A new study reveals the biological secret to the Zika virus's infectious success: Zika uses host cells' own 'self-care' system of clearing away useless molecules to suppress the host proteins that ...

New Factor Linked to Heart Failure

May 26, 2025 — When the workload on the heart increases, the ventricular wall may thicken too, known as cardiac hypertrophy. This is an adaptive response that reduces pressure on the heart and maintains the ...

Unlocking the Secrets of Bat Immunity

May 21, 2025 — Bats are known as natural hosts for highly pathogenic viruses such as MERS- and SARS-related coronaviruses, as well as the Marburg and Nipah viruses. In contrast to the severe and often fatal disease ...

Why Some Viral Infections Appear to Trigger Autoimmune Disease

May 20, 2025 — By studying Chikungunya virus, scientists shed light on how immune responses to viral infections may lead to persistent symptoms of autoimmune ...

Fast Food, Fast Impact: How Fatty Meals Rapidly Weaken Our Gut Defenses

May 19, 2025 — A study has become the first in the world to unravel the immediate effects of a high-fat diet on our gut ...

Maintaining Balance in the Immune System

May 19, 2025 — Researchers have published the first description of the role of the ZFP36 family of RNA binding proteins in regulatory T cells (Tregs). Tregs are key to maintaining balance in the immune system and ...

May 12, 2025 — Researchers confirm and explore the role of estrogen-related receptors in regulating energy production in muscle cells during exercise. The findings indicate that developing a drug to boost ...

Colonic Inflammation Explains Missing Link Between Obesity and Beta-Cell Proliferation

May 9, 2025 — How does obesity affect insulin production? Researchers are shining light on new stages of the ERK ...

MRI Breakthrough Could Revolutionize Diagnosis of Common Heart Problem Aortic Stenosis

May 8, 2025 — Researchers have developed cutting-edge MRI technology to diagnose a common heart problem more quickly and accurately than ever before. Aortic stenosis is a progressive and potentially fatal ...

A Digestive 'Treasure Chest' Shows Promise for Targeted Drug Treatment in the Gut

May 1, 2025 — A new approach to drug design can deliver medicine directly to the gut in mice at significantly lower doses than current inflammatory bowel disease treatments. The proof-of-concept study introduced a ...

Lower Screening Age Calls for More Tailored Bowel Cancer Surveillance

Apr. 30, 2025 — Australia's recent move to lower the starting age for bowel (colorectal) cancer screening from 50 down to 45 years old will mean better outcomes -- but it will also increase the burden on an ...

Hospitalized Patients Who Receive Alcohol Use Disorder Treatment Can Substantially Reduce Heavy Drinking

Apr. 21, 2025 — A new study found that the oral and extended-release injectable forms of naltrexone are equally effective in helping patients consume less alcohol, suggesting that clinicians should integrate this ...

Existing Drug Has Potential for Immune Paralysis

Apr. 18, 2025 — When the immune system does not function properly, individuals become more susceptible to infections caused by viruses, bacteria, or fungi. Researchers have demonstrated that an existing drug can ...

Early Mutations and Risk Factors for Stomach Cancer, and Develops a Pre-Cancer Model for Stomach Cancer Prevention

Apr. 16, 2025 — Researchers have made significant advancements in understanding the earliest stages of stomach cancer, a leading cause of cancer-related deaths worldwide, through two recent innovative studies. With ...

Brain Pathway Links Inflammation to Loss of Motivation, Energy in Advanced Cancer

Apr. 10, 2025 — Researchers identified a direct connection between cancer-related inflammation and the loss of motivation characteristic of advanced cancer. In a mouse study, they describe a brain pathway that ...

Discovery Reveals Protein Involved in Parkinson's Disease Also Drives Skin Cancer

Apr. 9, 2025 — A small protein involved in neurodegeneration leading to Parkinson's disease also drives a type of skin cancer known as melanoma, according to new ...

New Vaccine Concept Tackles Harmful Bacteria in the Intestine

Apr. 3, 2025 — In the fight against bacterial pathogens, researchers are combining vaccination with targeted colonization of the intestine by harmless microorganisms. This approach could potentially mark a turning ...

Patient Navigators Improve Colonoscopy Rates After Abnormal Stool Tests, Study Shows

Mar. 31, 2025 — Timely follow-up colonoscopies can reduce the mortality rate from colorectal cancer, and patient navigators can play an important role in facilitating ...

Mini Rolling Robot Takes Virtual Biopsies

Mar. 26, 2025 — A tiny magnetic robot which can take 3D scans from deep within the body, that could revolutionize early cancer detection, has been developed by researchers. The team say this is the first time it has ...

Enzyme Engineering Opens Door to Novel Therapies for Parkinson's, Cancers and Other Hard-to-Target Protein Diseases

Mar. 26, 2025 — Scientists have long struggled to target proteins that lack defined structure and are involved in cancer, neurodegenerative disorders like Parkinson's disease, and other serious illnesses. Now, ...

'Switch' Allows Intestinal Cells to Regenerate After Injury

Mar. 25, 2025 — Researchers have solved a cellular mystery that may lead to better therapies for colorectal and other types of cancer. A professor of pediatrics-developmental biology and an assistant professor of ...

Postpartum Female Preference for Cooler Temperatures Linked to Brain Changes

Mar. 25, 2025 — Mothers experience major metabolic adaptations during pregnancy and lactation to support the development and growth of the new life. Although many metabolic changes have been studied, body ...

Cellular Mechanisms That May Lead to Onset of Inflammatory Bowel Disease

Mar. 21, 2025 — New study shows that dysfunction of protective immune cells in GI tract may contribute to onset of inflammation in Crohn's ...

How a Y Chromosome Gene May Shape the Course of Heart Valve Disease

Mar. 20, 2025 — Researchers have shed new light on how a type of heart valve disease -- aortic valve stenosis -- progresses differently in males and ...

Treating Chronic Inflammatory Diseases With JAK Inhibitors

Mar. 17, 2025 — Janus kinase inhibitors (JAKis) are an important treatment option for people with chronic inflammatory diseases such as rheumatoid arthritis, psoriasis, Crohn's disease or ulcerative colitis. ...

Global Warming Can Lead to Inflammation in Human Airways, New Research Shows

Mar. 17, 2025 — In a recent, cross-institutional study partially funded by the National Institutes of Health, researchers report that healthy human airways are at higher risk for dehydration and inflammation when ...