Vaccines News

January 26, 2025

Top Headlines

A Therapeutic HPV Vaccine Could Eliminate Precancerous Cervical Lesions

Jan. 24, 2025 — A therapeutic vaccine targeting human papillomavirus type 16 (HPV16) induced regression in high-grade precancerous cervical lesions, according to the results from a phase II clinical ...

A Chain Reaction: HIV Vaccines Can Lead to Antibodies Against Antibodies

Jan. 17, 2025 — Many vaccines work by introducing a protein to the body that resembles part of a virus. Ideally, the immune system will produce long-lasting antibodies recognizing that specific virus, thereby providing protection. But scientists have now discovered ...

Child Undernutrition May Be Contributing to Global Measles Outbreaks, Researchers Find

Jan. 16, 2025 — Amid a global surge in measles cases, new research suggests that undernutrition may be exacerbating outbreaks in areas suffering from food insecurity. A study involving over 600 fully vaccinated ...

Bird Flu Is Mutating, but Antivirals Still Work

Jan. 15, 2025 — Researchers have identified nine mutations in a bird flu strain from a person in Texas. Bad news: this strain is more capable of causing disease and replicates better in the brain. Good news: approved antivirals are still ...

Latest Headlines

updated 10:53pm EST

Hepatitis E Vaccination Is Effective in an Epidemic

Jan. 14, 2025 — Hepatitis E, a potentially serious viral liver disease, is transmitted through contaminated water. The risk is particularly high in populations with limited access to safe water and sanitation. In ...

Self-Destructing Vaccine Offers Enhanced Protection Against Tuberculosis in Monkeys

Jan. 10, 2025 — The in-built in protection mechanisms offer a safer and more effective way to combat the deadliest disease of ...

T Cells' Capability to Fully Prevent Acute Viral Infections Opens New Avenues for Vaccine Development

Jan. 10, 2025 — Scientists have discovered that T cells -- white blood cells that can destroy harmful pathogens -- can completely prevent viral infection, to an ...

Researchers Discover Class of Anti-Malaria Antibodies

Jan. 3, 2025 — Antibodies that bind to a previously untargeted portion of the malaria parasite could lead to new monoclonal antibody treatments and vaccines for ...

Officials Assess Threat of H5N1 Avian Flu

Jan. 2, 2025 — Highly pathogenic H5N1 avian influenza A virus (HPAI H5N1) remains a low risk to the general public, and public health experts in the United States believe that available treatments and vaccines, as ...

System to Auto-Detect New Variants Will Inform Better Response to Future Infectious Disease Outbreaks

Jan. 1, 2025 — Researchers have come up with a new way to identify more infectious variants of viruses or bacteria that start spreading in humans -- including those ...

People Who Are Immunocompromised May Not Produce Enough Protective Antibodies Against RSV After Vaccination

Dec. 30, 2024 — Researchers have shown that people 60 years or older with weakened immunity do not respond as strongly to vaccines against the respiratory syncytial ...

'Unbreakable' Lassa Vaccine Shows Promising Results

Dec. 18, 2024 — A live-attenuated vaccine under development is safe and 100% effective against Lassa virus in preclinical ...

Public Shows Greater Acceptance of RSV Vaccine as Vaccine Hesitancy Appears to Have Plateaued

Dec. 23, 2024 — A year after becoming available, vaccines to protect against RSV in newborns and older adults are being more widely accepted by the American public, ...

Scientists Design Workaround That Improves Response to Flu Vaccine

Dec. 19, 2024 — Stitching together four molecules found in the standard flu vaccine ensures an immune response to all of them, scientists have ...

Study Shows Drop in Use of Antiviral Medications in Young Children With Influenza

Dec. 17, 2024 — Despite national medical guidelines supporting the use of antiviral medications in young children diagnosed with influenza, a recent study reports an underuse of the ...

Staphylococcus Aureus Thwarts Vaccines by Turning on a Protein That Halts Immune Response

Dec. 16, 2024 — After dozens of clinical trials, there are still no effective vaccines against Staphylococcus aureus. In two new studies, scientists report that the pathogen turns on the protein interleukin 10, ...

Model Advances Rational Design of More Effective Maternal Vaccines for Newborns

Dec. 12, 2024 — Research on vaccines may help save more ...

Updated Hep B Vaccine More Effective for People With HIV

Dec. 10, 2024 — A newer vaccine against hepatitis B virus was clearly superior to an older vaccine type in inducing a protective antibody response among people living with HIV who didn't respond to prior ...

Americans Are Uninformed About and Undervaccinated for HPV

Dec. 10, 2024 — Research shows that HPV accounts for 70% of all throat cancers, but only one-third of the public is aware that HPV causes throat ...

Rotavirus Vaccine Is Safe for Use in NICU Babies, Study Suggests

Dec. 9, 2024 — Researchers found that transmission of rotavirus vaccine strains in a neonatal intensive care unit (NICU) is rare and without clinical consequences, strongly suggesting that giving the rotavirus ...

Pregnancy Enhances Natural Immunity to Block Severe Flu

Dec. 2, 2024 — Scientists have discovered that pregnancy may trigger a natural immunity to boost protection against severe flu infection. Contrary to the common belief that pregnancy increases vulnerability to ...

Cervical Cancer Deaths in Young Women Plummet After Introduction of HPV Vaccine

Nov. 27, 2024 — Researchers found a reduction in cervical cancer mortality in women under the age of 25, which is likely due to the introduction of the HPV ...

Stopping Severe Malaria by Harnessing Natural Human Antibodies

Nov. 20, 2024 — Scientists have identified human antibodies capable of targeting the proteins responsible for severe malaria, potentially paving the way for new vaccines or treatments. Using organ-on-a-chip ...

Researchers Use Biophysics to Design New Vaccines Against RSV and Related Respiratory Viruses

Nov. 19, 2024 — In most people, the lung-infecting pathogens known as respiratory syncytial virus (RSV) and human metapneumovirus (hMPV) trigger mild cold-like symptoms. But in infants and seniors, these viruses can ...

New Nasal Vaccine Shows Promise in Curbing Whooping Cough Spread

Nov. 18, 2024 — A new nasal whooping cough vaccine showed an ability to prevent both infection and transmission of the disease in mice. Current vaccines offer treatment but fail to halt transmission of the bacteria ...

Potential Single-Dose Smallpox and Mpox Vaccine Moves Forward

Nov. 13, 2024 — An FDA-approved vaccine for smallpox and mpox is effective but causes side effects. The other requires multiple doses. An experimental single-dose vaccine uses the horsepox virus to harness the ...

Study Reveals Best Timing for Getting the RSV Vaccine During Pregnancy to Protect Newborns

Nov. 11, 2024 — Current guidelines recommend that pregnant people receive a vaccine against respiratory syncytial virus (RSV) -- which typically causes mild, cold-like symptoms in most adults but can be deadly for ...

New Study Traces Impact of COVID-19 Pandemic on Global Movement and Evolution of Seasonal Flu

Nov. 7, 2024 — Increased capabilities for genomic surveillance have offered new insights into global viral evolution. Seasonal flu showed a 'remarkable' bounce back to pre-pandemic levels once ...

RSV Vaccines Effective, but More People Need to Get Them

Oct. 28, 2024 — Doctors detail what we learned after the first season following the approval of RSV vaccines. The vaccine effectively prevented severe illness in older, but only 24 percent of eligible US adults ...

Maternal Antibodies Interfere With Malaria Vaccine Responses

Oct. 24, 2024 — Maternal antibodies passed across the placenta can interfere with the response to the malaria vaccine, which would explain its lower efficacy in infants under five months of age, according to new ...

Study Finds Tuberculosis Changes Liver Metabolism and Could Promote Diabetes

Oct. 21, 2024 — Scientists have discovered that tuberculosis disrupts glucose metabolism in the ...

Big Data, Real World, Multi-State Study Finds RSV Vaccine Highly Effective in Protecting Older Adults Against Severe Disease, Hospitalization and Death

Oct. 17, 2024 — This multi-state study is a real world data analyses of the effectiveness of the RSV -- short for respiratory syncytial virus -- vaccine. VISION Network researchers report that across the board these ...

New mRNA Vaccine Created to Prevent and Treat C. Difficile

Oct. 17, 2024 — A new vaccine provides hope for treating and even preventing the highly contagious and difficult-to-treat Clostridioides difficile infection, more commonly known as C. difficile or C. diff. In animal ...

Study May Help Boost Performance and Reduce Side Effects of mRNA Vaccines

Oct. 17, 2024 — A new study has provided a detailed analysis of how mRNA vaccines circulate and break down in the human bloodstream. The research aimed to help improve the safety and effectiveness of these vaccines, ...