Immune System News

June 25, 2025

Top Headlines

How Brain Cells Meant to Help May Be Making Depression Worse

June 24, 2025 — Major depressive disorder affects hundreds of millions worldwide, but a key to understanding its origins may lie in the brain’s immune system. New findings spotlight astrocytes—previously overshadowed by microglia—as major players in ...

Tea, Berries, Dark Chocolate and Apples Could Lead to a Longer Life Span, Study Shows

June 3, 2025 — Eating a colorful variety of flavonoid-rich foods like tea, berries, dark chocolate, and apples may significantly lower your risk of chronic diseases and even help you live longer. A major study ...

Large-Scale Immunity Profiling Grants Insights Into Flu Virus Evolution

June 3, 2025 — A new study shows how person-to-person variation in antibody immunity plays a key role in shaping which influenza (flu) strains dominate in a ...

Preventing Chronic Inflammation from Turning Into Cancer

June 2, 2025 — Chronic inflammatory bowel disease is challenging to treat and carries a risk of complications, including the development of bowel cancer. Young people are particularly affected: when genetic predisposition and certain factors coincide, diseases ...

Innovative Immunotherapy Shows Promise Against Aggressive T Cell Cancers

May 30, 2025 — An international clinical trial shows an innovative CAR-T cell immunotherapy is promising against aggressive T cell cancers and has manageable side ...

Potential to Prevent and Treat a Common Type of Inflammatory Arthritis Advanced by the Identification of New Genetic Links

May 30, 2025 — Researchers have discovered two genes, RNF144B and ENPP1, that cause calcium pyrophosphate deposition (CPPD) disease in Americans of European and African descent. This crystalline arthritis is caused ...

PREVENT Equation Accurately Estimated 10-Year CVD Risk and Those With Calcium Buildup

May 23, 2025 — A new risk calculator accurately identified participants who had calcium buildup in their heart arteries and those who had a higher future heart attack risk, in an analysis of about 7,000 adults in ...

'Barcodes' Written Into Our DNA Reveal How Blood Ages

May 22, 2025 — A study explains how age reshapes the blood system. In both humans and mice, a few stem cells out-compete their neighbors and gradually take over blood production. The loss of diversity results in a blood system that has a preference for producing ...

Why Some Viral Infections Appear to Trigger Autoimmune Disease

May 20, 2025 — By studying Chikungunya virus, scientists shed light on how immune responses to viral infections may lead to persistent symptoms of autoimmune ...

Fast Food, Fast Impact: How Fatty Meals Rapidly Weaken Our Gut Defenses

May 19, 2025 — A study has become the first in the world to unravel the immediate effects of a high-fat diet on our gut ...

Maintaining Balance in the Immune System

May 19, 2025 — Researchers have published the first description of the role of the ZFP36 family of RNA binding proteins in regulatory T cells (Tregs). Tregs are key to maintaining balance in the immune system and essential to preventing autoimmune disease. By the ...

Protein Switch Turns Anti-Viral Immune Response on and Off

May 16, 2025 — An international research team has discovered a critical protein that acts as a 'switch' regulating immune responses to ...

Latest Headlines

updated 11:58am EDT

CAR-T Cell Therapy for Cancer Causes 'Brain Fog,' Study Shows

May 12, 2025 — Cancer treatment with a cell-based immunotherapy causes mild cognitive impairment, a Stanford Medicine team found. They also identified compounds that could treat ...

Colonic Inflammation Explains Missing Link Between Obesity and Beta-Cell Proliferation

May 9, 2025 — How does obesity affect insulin production? Researchers are shining light on new stages of the ERK ...

Enhanced CAR T Cell Therapy Offers New Strategy for Lymphoma

May 8, 2025 — A phase I study of a next-generation CAR T cell therapy showed a 52 percent complete remission rate for patients with relapsed/refractory ...

Vaccines of the Future: Harnessing the Immune System for Long-Lasting Protection

May 8, 2025 — Scientists have uncovered a promising new way to enhance the effectiveness of vaccines by tapping into the potential of a specific type of immune ...

Explaining the Link Between 'Good' Gut Bacteria and Rheumatoid Arthritis

May 4, 2025 — After spending years tracing the origin and migration pattern of an unusual type of immune cell in mice, researchers have shown in a new study how activity of 'good' microbes in the gut is linked to ...

Treatment Regimen for Aggressive Blood Cancer

May 4, 2025 — Study data reveal how a specific sequence of cancer therapies can improve outcomes for patients with hard-to-treat ...

A Drug Dismantles a Metabolic Barrier to Anti-Tumor Immunity

Apr. 30, 2025 — A new study has identified a specific mode of fat uptake by immune cells within tumors that serves as a metabolic checkpoint against anti-cancer immune ...

How Bacteria in Our Aging Guts Can Elevate Risk of Leukemia and Perhaps More

Apr. 25, 2025 — Scientists have discovered a surprising new connection between gut health and blood cancer risk one that could transform how we think about aging, ...

Immune Cells Drive Congenital Paralysis Disease

Apr. 25, 2025 — Patients with spastic paraplegia type 15 develop movement disorders during adolescence that may ultimately require the use of a wheelchair. In the early stages of this rare hereditary disease the ...

B Cells Found to Be Crucial for Long-Term Vaccine Protection, New Study Shows

Apr. 23, 2025 — Researchers have uncovered a critical, previously underappreciated role for B cells in vaccine protection. Best known for producing antibodies, B ...

Can Hormone Therapy Improve Heart Health in Menopausal Women?

Apr. 22, 2025 — Oral hormone therapy may benefit heart health in menopausal women. A new analysis of data from the Women's Health Initiative found that estrogen-based oral hormone therapy had a long-term ...

Empowering Antibodies to Better Activate the Immune System

Apr. 22, 2025 — Antibodies are best known for their ability to latch onto and neutralize bacteria, viruses and other pathogens. But these immune proteins can do more than that: They also activate other components of ...

Existing Drug Has Potential for Immune Paralysis

Apr. 18, 2025 — When the immune system does not function properly, individuals become more susceptible to infections caused by viruses, bacteria, or fungi. Researchers have demonstrated that an existing drug can ...

Uncovering the Molecular Drivers of Liver Cancer

Apr. 15, 2025 — Researchers discover that inflammation and aging contribute to non-viral liver cancer development: Green tea's role in reversing some of the pathway dysregulation that may contribute to the ...

Recently Discovered Immune Cell Type Is Key to Understanding Food Allergies

Apr. 14, 2025 — A new study has revealed that a special group of cells in the intestines tamp down the immune responses caused by exposure to food proteins. Called 'tolerogenic dendritic cells,' these ...

New Phase of the Immune Response Uncovered

Apr. 10, 2025 — A team has identified a previously unknown phase of the immune response. The results challenge long-standing assumptions about the process called 'T-cell priming'. These new insights have ...

Study Shows How New Antibody Therapy Works Against Ovarian Cancer

Apr. 10, 2025 — Research has shed light on how a new type of antibody treatment reactivates patients' immune cells to fight ovarian ...

A Gentle Approach Offers New Hope for Inflammatory Lung Diseases

Apr. 7, 2025 — Pulmonary sarcoidosis is a lung disease characterized by granulomas -- tiny clumps of immune cells that form in response to inflammation. It's the most inflammatory of the interstitial lung ...

Molecules That Fight Infection Also Act on the Brain, Inducing Anxiety or Sociability

Apr. 7, 2025 — Scientists find the protein IL-17 that fights infection also acts on the brain, inducing anxiety or sociability. This adds to evidence that immune molecules can influence behavior during ...

NK Cells Complexed With Bispecific Antibody Yield High Response Rates in Patients With Lymphoma

Apr. 4, 2025 — A novel cell therapy approach using cord blood-derived natural killer (NK) cells pre-complexed with AFM13, or acimtamig, a CD30/CD16A bispecific antibody, was safe and generated strong response rates ...

Researchers Develop Test Using Machine Learning to Help Predict Immunotherapy Response in Lymphoma Patients

Apr. 1, 2025 — A new article outlines a new tool that measures blood inflammation as a marker for poor CAR T therapy ...

How a Critical Enzyme Keeps Potentially Dangerous Genes in Check

Mar. 28, 2025 — The new study reveals a remarkable way that cells keep us safe from transposable elements (TEs) gone wild. The researchers found that cells have taken advantage of an entire protein network to ...

mRNA-Based COVID-19 Vaccines Train the 'Long-Term Memory' of the Immune System

Mar. 26, 2025 — Researchers have discovered that mRNA-based COVID-19 vaccines have a persistent effect on the innate immune system. These mechanisms may help the human body to better protect itself against potential ...

How Zika Virus Knocks out Our Immune Defenses

Mar. 25, 2025 — This research comes as many mosquito-borne viruses are spreading ...

Peacekeeper Cells Protect the Body from Autoimmunity During Infection

Mar. 21, 2025 — New research shows how a specially trained population of immune cells keeps the peace by preventing other immune cells from attacking their own. The study provides a better understanding of immune ...

Cellular Mechanisms That May Lead to Onset of Inflammatory Bowel Disease

Mar. 21, 2025 — New study shows that dysfunction of protective immune cells in GI tract may contribute to onset of inflammation in Crohn's ...

New Study Challenges Assumptions About SEP-1 Bundle Compliance and Sepsis Outcomes

Mar. 19, 2025 — A new study raises critical questions about the effectiveness of the Centers for Medicare and Medicaid Services' (CMS) sepsis quality measure, known as the Severe Sepsis/Septic Shock Management ...

Researchers Find Missing Link in Autoimmune Disorder

Mar. 18, 2025 — Scientists have identified a protein in cells that spurs the release of infection-fighting molecules. The protein, whose role in the immune system had not previously been suspected, provides a ...

Global Warming Can Lead to Inflammation in Human Airways, New Research Shows

Mar. 17, 2025 — In a recent, cross-institutional study partially funded by the National Institutes of Health, researchers report that healthy human airways are at higher risk for dehydration and inflammation when ...

Focus on the Gut-Liver Axis: Semisynthetic Bile Acid Has Anti-Inflammatory Effects on the Gut

Mar. 13, 2025 — A research team has made further progress in the treatment of intestinal inflammation. A study shows that the semi-synthetic bile acid NorUDCA inhibits in the intestine the formation of ...