Personalized Medicine News

March 2, 2025

Top Headlines

New Genetic Risk Score Identifies Individuals at Risk for Heart Disease Who May Benefit Most from Cholesterol-Lowering Therapies

Feb. 26, 2025 — Coronary artery disease (CAD), or the narrowing of the coronary arteries, is the leading cause of morbidity and mortality throughout the world. Atherosclerosis, or the buildup of plaque in the ...

Discovery of Rare Gene Variants Provides Window Into Tailored Type 2 Diabetes Treatment

Feb. 26, 2025 — A new study details the discovery of rare gene variants that increase the prevalence of Type 2 diabetes in multiple generations of Asian Indian people. The unusual finding is a step toward more ...

Hidden Genetic Causes of Congenital Heart Disease Identified

Feb. 20, 2025 — Scientists have identified novel genetic interactions that may contribute to congenital heart disease (CHD), a common birth ...

Almost 90% of People Would Agree to Genetic Testing to Tailor Medication Use, Survey Finds

Feb. 19, 2025 — New research shows almost 90% of people in England would agree to genetic testing to get the most effective medication and reduce the risk of side ...

Latest Headlines

updated 10:55pm EST

Gene Therapy for Rare Epilepsy Shows Promise in Mice

Feb. 14, 2025 — Recent research takes aim at the a variant in gene SCN1B, which causes a severe form of developmental epileptic ...

AI Unlocks Genetic Clues to Personalize Cancer Treatment

Feb. 11, 2025 — A groundbreaking study has uncovered how specific genetic mutations influence cancer treatment outcomes -- insights that could help doctors tailor treatments more effectively. The largest study of ...

New Perspectives for Personalized Therapy of Brain Tumors

Feb. 11, 2025 — Scientists have developed an innovative method for growing brain tumors of individual patients in the laboratory that mimic the original structure and the molecular property of the parental tumor as ...

Personalized Cancer Treatment Using 3D Bioprinting Technology

Feb. 7, 2025 — Scientists have successfully developed a gastric cancer model using 3D bioprinting technology and patient-derived cancer tissue fragments. This innovative model preserves the characteristics of ...

Novel PET Approach Identifies Early Signs of Pulmonary Arterial Hypertension

Jan. 22, 2025 — A new molecular imaging technique -- 18F-FAPI PET -- can detect the first signs of tissue remodeling in patients with pulmonary arterial hypertension ...

Cancer Vaccine Shows Promise for Patients With Stage III and IV Kidney Cancer

Feb. 5, 2025 — Researchers report that all nine patients in a clinical trial being treated for stage III or IV clear cell renal cell carcinoma (a form of kidney ...

Artificial Intelligence Improves Personalized Cancer Treatment

Jan. 30, 2025 — Personalized medicine aims to tailor treatments to individual patients. Until now, this has been done using a small number of parameters to predict the course of a disease. However, these few ...

Inherited Gene Elevates Prostate Cancer Risk in Affected Families

Jan. 28, 2025 — The inherited mutated gene WNT9B, which functions normally in embryonic prostate development, increases risk of adult prostate cancer, according to a new ...

Genetic 'Fingerprint' to Predict Drug Resistance in Bacteria

Jan. 28, 2025 — New research has identified a unique genetic signature in bacteria that can predict their likelihood of developing antibiotic resistance, a finding that can help quickly identify precision-based ...

Combination of Dual-Targeted Therapies and Chemotherapy Shows High Response Rates in BRAF-Mutated Metastatic Colorectal Cancer

Jan. 25, 2025 — Patients with metastatic colorectal cancer (mCRC) harboring BRAF V600E mutations benefited from first-line treatment with the targeted therapies ...

Predicting How Childhood Kidney Cancers Develop

Jan. 23, 2025 — New research looked at how cancers arise in children who are predisposed to developing the childhood kidney cancer, Wilms tumor, which could help anticipate the development of tumors before they ...

How Your Brain Learns from Rewards Might Hold the Key to Treating Depression

Jan. 22, 2025 — Using computational models, the researchers studied how the brain's reward-learning system functions in those with depression, especially among individuals experiencing anhedonia, the inability ...

Monitoring Tumor-Informed Circulating Tumor DNA After CGP

Jan. 15, 2025 — A research team proposes a method to assess cancer patients for their likelihood to either respond to treatment or ...

SCP-Nano: A New Technology to Visualize Nanocarriers in Cells and Tissues

Jan. 14, 2025 — How can we ensure that life-saving drugs or genetic therapies reach their intended target cells without causing harmful side effects? Researchers have taken an important step to answer this question. ...

Scientists Identify Genes Driving Cancer Spread

Jan. 9, 2025 — Cancer metastasis -- the spread of cancer to other organs -- is the leading cause of death among cancer patients. Researchers have now uncovered a 'genetic signature' of 177 genes shared ...

Researchers Resolve Uncertainty in BRCA2 Testing, Improving Cancer Risk Assessment and Patient Care

Jan. 8, 2025 — Findings from a multi-institutional, international study have significantly advanced the understanding of genetic alterations in the BRCA2 gene, a key player in hereditary cancer ...

Discovery Links Cellular Structures to Kidney Cancer Treatment Outcomes

Jan. 2, 2025 — Fighting cancer can seem like a deadly game of chance. While some patients may respond well to certain treatments, others might not be as fortunate. Doctors and scientists have long struggled to ...

Genetic Testing Changes Course of Care in Children With Neurodevelopmental Conditions

Dec. 18, 2024 — Adding genetic testing to the evaluation of pediatric patients with neurodevelopmental disorders (NDD) resulted in more individualized ...

Study Finds New Blood Test Predicts Prognosis for Advanced Prostate Cancer Patients

Dec. 11, 2024 — A new study found that a DNA sequencing test for advanced prostate cancer patients can distinguish between patients with poor and favorable ...

Personalized Blood Count Could Lead to Early Intervention for Common Diseases

Dec. 11, 2024 — A complete blood count (CBC) screening is a routine exam requested by most physicians for healthy adults. Currently, the results of CBC tests are analyzed using a one-size-fits-all reference ...

Brain Tumor Organoids Accurately Model Patient Response to CAR T Cell Therapy

Dec. 9, 2024 — Researchers used lab-grown organoids created from tumors of individuals with glioblastoma (GBM) to accurately model a patient's response to CAR T cell therapy in real time. The organoid's ...

Genetic Data from 'Biobanks' May Help Improve Prediction of Effectiveness, Side Effects of Common Medications

Dec. 4, 2024 — A new study has outlined a new framework that researchers say would improve predictive power of genetics to determine how well a patient would respond to commonly prescribed medications as well as ...

Largest-Ever Exome Study Offers Blueprint for Biomedical Breakthroughs

Dec. 3, 2024 — Scientists have achieved a significant milestone generating a large collection of exome data, which include genes that code for proteins -- key to understanding health and ...

Genetic Variation Enhances Cancer Drug Sensitivity

Nov. 14, 2024 — By exploiting the genetic variation in cancer cells, an already approved cancer drug demonstrated enhanced effects against cancer cells in specific patient groups, according to a new study. The ...

Genomic Databases Need More Diversity, Experts Say

Nov. 6, 2024 — Researchers have developed a broad and deep genomic database of Latin Americans which gathers genome-wide data of Latin American populations into a single source and allows other scientists to easily ...

Precision Robotics Offers Hope for Heart Disease Treatment

Oct. 30, 2024 — The advanced drug testing system screens multiple potential therapies simultaneously in beating heart ...

New Method to Analyze Complex Genetic Data Could Be the Key to Tackling Rare Diseases

Oct. 30, 2024 — Scientists have developed a new method of genetic analysis, which extracts more precise data than previously used methods when looking at DNA, and will improve our understanding of the genetic basis ...

Using AI to Measure Prostate Cancer Lesions Could Aid Diagnosis and Treatment

Oct. 29, 2024 — Prostate cancer is the second most common cancer in men, and almost 300,000 individuals are diagnosed with it each year in the U.S. To develop a consistent method of estimating prostate cancer size, ...

New Research Could Lead to Genetically Tailored Diets to Treat Patients With IBS

Oct. 21, 2024 — An international study has found that genetic variations in human carbohydrate-active enzymes may affect how people with irritable bowel syndrome (IBS) respond to a carbohydrate-reduced ...

Large-Scale Study of Children With Genetic Disorders Finds Huge Benefit of Diagnosis

Oct. 15, 2024 — Genetic results from the Deciphering Developmental Disorders (DDD) study have enabled thousands of children with severe developmental disorders to receive better ...