Skin Cancer News

November 27, 2024

Top Headlines

Scientists Identify Key Mechanism in Development of Skin Cancer

Nov. 22, 2024 — Researchers have discovered how the interplay between a key protein and an endolysosomal ion channel promotes tumor development in skin ...

Study Identifies Subtypes of Fibroblasts in Skin Cancer

Nov. 19, 2024 — A study provides insights into the diversity of cancer-associated fibroblasts in white and black skin cancer and describes their different immunomodulatory roles in the tumor environment. The results are relevant for the development of novel skin ...

AI Model That Checks for Skin Cancer Shows Promise

Oct. 17, 2024 — Scientists developed a way of using artificial intelligence to check for skin cancer with the AI tool, which was trained on data from 53,601 skin lesions from 25,105 patients, outperforming existing methods in a new ...

Estrogens Play a Hidden Role in Cancers, Inhibiting a Key Immune Cell

Sep. 27, 2024 — Estrogens are known to drive tumor growth in breast cancer cells that carry its receptors, but a new study unexpectedly finds that estrogens play a role in fueling the growth of breast cancers without the receptors, as well as numerous other ...

Latest Headlines

updated 10:48pm EST

Long-Term Metastatic Melanoma Survival Dramatically Improves on Immunotherapy, Study Finds

Sep. 16, 2024 — Long-term data from a landmark international trial show about half of patients with metastatic melanoma treated with a combination of immune ...

Experimental mRNA Cancer Vaccine Shows Potential for Advanced Stage Cancer Patients in Phase 1 Trial

Sep. 13, 2024 — Interim data from the Phase I dose escalation part of the mRNA cancer immunotherapy (mRNA-4359), show promise in patients with advanced solid ...

Sex Matters in How, When, and Where Melanomas Develop, Study Finds

Sep. 12, 2024 — A study analyzing long-term melanoma data reveals important insights into melanoma incidence trends in men and ...

Breaking the Trend: Skin Cancer Incidence in Young Adults Declines

Sep. 9, 2024 — The risk of skin cancer for adults under the age of 50 is now decreasing for the first time in ...

Sep. 6, 2024 — Age-related changes in the fibroblasts, cells that create the skin's structure, contribute to the development of aggressive, treatment-resistant ...

Combo Immunotherapy Produces Distinct Waves of Cancer-Fighting T Cells With Each Dose

Aug. 29, 2024 — A new tool for monitoring immune health patterns over time reveals how a pair of checkpoint inhibitor therapies works together to recruit new ...

Tumor-Infiltrating Lymphocyte Therapy Marks a Milestone in Cancer Treatment

July 18, 2024 — Scientists provide a comprehensive overview of the evolution and potential of TIL therapy. They describe its development and highlight its transformative ...

The Mechanism Behind Melanoma Resistance to Treatment

June 27, 2024 — In many cases of malignant melanoma, the effect of targeted treatment is lost over time. A research team has now discovered that a factor secreted by tumor cells is responsible for the resistance. ...

How Targeted Nutrients Can Fight Cancer

June 18, 2024 — An international research team has discovered a new way to effectively treat cancer, by using nutrients to reactivate suppressed metabolic pathways in cancer ...

Transfer RNAs at the Heart of Therapeutic Resistance

June 7, 2024 — Scientists have discovered an interesting new therapeutic target for the treatment of melanoma resistant to targeted therapies. Inhibition of the VARS enzyme could prevent this therapeutic resistance ...

Inherited Genes Play a Larger Role in Melanoma Risk Than Previously Believed

May 23, 2024 — A new study shows that genetics play a larger role in melanoma risk than recognized. Researchers report that up to 15% (1 in 7) of patients who received melanoma diagnoses from Cleveland Clinic ...

Plant Virus Treatment Shows Promise in Fighting Metastatic Cancers in Mice

May 13, 2024 — An experimental treatment made from a plant virus is effective at protecting against a broad range of metastatic cancers in mice, shows a new study. The treatment, composed of nanoparticles fashioned ...

Melanoma in Darker Skin Tones

May 10, 2024 — Melanoma, an aggressive form of skin cancer that accounts for 75% of all skin-cancer-related deaths, is often detected later in people with darker skin complexions -- and the consequences can be ...

Years After His Death, Late Scientist's Work Could Yield New Cancer Treatments

May 7, 2024 — Recent reproductive research has opened the door for new treatments for solid cancer tumors, including breast cancer, lung cancer and ...

Gene Signatures from Tissue-Resident T Cells as a Predictive Tool for Melanoma Patients

May 2, 2024 — A new study has revealed an association between favorable survival outcomes for melanoma patients and the presence of higher populations of tissue-resident memory T cells (TRM). Data obtained from ...

New Insights Could Unlock Immunotherapy for Rare, Deadly Eye Cancer

Apr. 16, 2024 — New research explains why metastatic uveal melanoma is resistant to conventional immunotherapies and how adoptive therapy, which involves growing a patient's T cells outside the body before ...

AI-Based App Can Help Physicians Find Skin Melanoma

Mar. 20, 2024 — A mobile app that uses artificial intelligence, AI, to analyze images of suspected skin lesions can diagnose melanoma with very high precision, according to a new ...

Scientists Enhance Cell-Based Therapy to Destroy Solid Tumors

Dec. 13, 2023 — Researchers successfully tested a simple intervention that could unlock greater anti-tumor power in therapies that use T cells -- an approach known as 'cell-based therapy,' which uses ...

Researchers Identify Cell Signaling Pathway Controlling Melanoma Cell Metastasis to the Brain

Nov. 29, 2023 — Researchers have been working to better understand what drives melanoma brain metastasis. They now report on the identification of a cell signaling pathway that regulates the metastatic spread of ...

Study Reveals Hidden Immune Defense Against Cancer

Nov. 28, 2023 — Researchers have found certain immune cells can still fight cancer even when the cancer cells lack an important protein that the immune system relies on to help track down cancer ...

The Sunscreen Paradox: Researchers Warn of 'False Sense of Security'

Oct. 27, 2023 — Sunscreen usage is climbing, but so are melanoma and skin cancer rates: this, researchers say, is the sunscreen ...

New Insights Into Melanoma Development and Therapy

Sep. 5, 2023 — Researchers have revealed that the expression of a specific isoform of GREB1 Is4 is induced in malignant melanoma cells by the melanocyte-specific transcription factor, MITF. They revealed that GREB1 ...

Why Men, Wealthy People and Maritime Residents Are More Likely to Develop Skin Cancer

Aug. 31, 2023 — A new study examines why people living in Atlantic regions are more at-risk for developing melanoma than other Canadians, providing lessons on skin cancer prevention for the whole country. To find ...

A Medication Used for Heart Conditions Improves the Efficacy of Current Treatments for Melanoma in Mouse Models

Aug. 10, 2023 — The administration of ranolazine, a drug currently used to treat heart conditions, improves the efficacy of current therapies for melanoma, in mouse models of this ...

New RNA-Based Therapy Combats Melanoma in Mouse Models

July 27, 2023 — Investigators have designed an innovative RNA-based strategy to activate dendritic cells--which play a key role in immune response -- that eradicated tumors and prevented their recurrence in mouse ...

Immobilizing Melanoma

July 26, 2023 — Although rare, mucosal melanoma in humans has a low survival rate. It has been difficult to investigate due to a lack of similar cancers in animals for study. Researchers explored a protein common to ...

A Two-for-One Approach to Boost Melanoma Immunotherapy

July 5, 2023 — New research has helped explain how melanoma evades the immune system and may guide the discovery of future therapies for the ...

Vaccine Delivers a Boost to T Cell Therapy

July 5, 2023 — A new vaccine boosts the response of engineered CAR-T cells and helps the immune system generate T cells that target other tumor antigens. The researchers found this approach made it more likely that ...

Researchers Uncover Potential Biomarkers of Positive Response to Immunotherapy

June 26, 2023 — Scientists have identified potential new biomarkers that could indicate how someone diagnosed with metastatic melanoma will respond to immunotherapy ...

Researchers Uncover Immune Cell Marker and Regulator of Anti-Tumor Immunity

June 23, 2023 — B cells are thought to play a critical role in innate and adaptive immunity, but their exact role in anti-tumor immunity remains unknown. Researchers with expertise in immunology collaborated with ...