Amyotrophic Lateral Sclerosis News
March 25, 2025
Top Headlines
Feb. 26, 2025 — ALS, or amyotrophic lateral sclerosis, can sometimes be difficult to diagnose or to predict how quickly the disease is likely to progress. A new study helps determine which blood tests are best at identifying and monitoring ...
Aug. 22, 2024 — Scientists have found that the protein histone H1.2 and the enzyme PARP1 could be potential therapeutic targets to decrease neurodegeneration in amyotrophic lateral sclerosis ...
Aug. 14, 2024 — A new brain-computer interface translates brain signals into speech with up to 97 percent accuracy. Researchers implanted sensors in the brain of a man with severely impaired speech due to amyotrophic lateral sclerosis (ALS). The man was able to ...
Aug. 8, 2024 — Researchers have used a new technique to identify pathological abnormalities associated with motor neurone ...
Latest Headlines
updated 3:49pm EDT
Nov. 8, 2024 — Researchers identify a key pathway leading to neurodegeneration in early stages of ALS, hinting at the potential for short-circuiting the progression of the fatal disease if diagnosed ...
July 10, 2024 — The study provides the basis for a phase I clinical trial in additional ...
Mar. 13, 2024 — Participation in recreational activities -- including golfing, gardening or yard work, woodworking and hunting -- may be associated with an increase ...
Mar. 13, 2024 — Defects in the blood vessel network of the central nervous system have been linked to early symptoms of neurodegenerative diseases such as ...
Feb. 22, 2024 — Scientists have developed an innovative neural cell culture model, shedding light on the intricate mechanisms underlying neurodegeneration. Their ...
Feb. 8, 2024 — A new pharmacological inhibitor can intervene in a central cell death mechanism that is responsible for the death of motor neurons and hence important for the progression of the motor neuron disease ...
Jan. 10, 2024 — In people with amyotrophic lateral sclerosis (ALS), changes in neurons appear to activate immune cells. Lowering the inflammation could reduce the symptoms of the disease, according to a new ...
Jan. 4, 2024 — Scientists identify ALS-linked protein VAP as a key stabilizer of mitochondria near dendritic spines to support memory formation. This finding opens new directions for research into cognitive and ...
Dec. 4, 2023 — Neurodegenerative diseases are characterized by the deposition of clumped proteins in the brain and progressive neuronal cell death. Although the causal link between protein aggregates and ...
Nov. 16, 2023 — Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that affects neurons in the brain and spinal cord causing loss of muscle control. ...
Earlier Headlines
Sep. 22, 2023 — A research group has found a promising drug candidate for the treatment of amyotrophic lateral sclerosis (ALS). Cerebral dopamine neurotrophic factor CDNF prolongs the lifespan of and alleviates ...
Sep. 18, 2023 — Researchers have developed an evidence-based consensus guidelines for genetic testing and counseling for patients with amyotrophic lateral sclerosis (ALS), a neurodegenerative disease that affects ...
Aug. 18, 2023 — Amyotrophic lateral sclerosis (ALS) is a widespread neurodegenerative disease caused by the loss of neurons that control movement. Although abnormal accumulation of proteins called TDP-43 accompanies ...
July 21, 2023 — Researchers have shown that hundreds of proteins and mRNA molecules are found in the wrong place in nerve cells affected by Motor Neuron Disease (MND), also known as Amyotrophic Lateral Sclerosis ...
June 2, 2023 — Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a fatal motor neuron disease that causes people to gradually lose control of their muscles. There is no cure, and ...
Mar. 16, 2023 — Researchers use a DNA designer drug to restore key protein levels in motor neurons, delaying paralysis in a mouse model of ...
Mar. 10, 2023 — Researchers have identified a new therapeutic target that could lead to more effective treatment of ...
Feb. 27, 2023 — Scientists know that TDP-43, which helps regulate processing of RNA, may be responsible for the death of nerve cells in ALS and frontotemporal dementia. And a study suggests that a common ...
Feb. 2, 2023 — A new microscopic technique allows for the real-time study of RNA G-quadruplexes in living cells, with implications for the fight against amyotrophic lateral ...
Dec. 1, 2022 — Scientists have taken a key step toward better understanding neurodegenerative diseases by using a suite of biophysical techniques to learn more about a motor protein whose malfunction is associated ...
Sep. 21, 2022 — An international phase 3 clinical trial for a rare, inherited form of ALS showed that an investigational drug, known as tofersen, reduced molecular signs of disease, but at six months did not improve ...
Sep. 21, 2022 — Scientists believe a new genetically-targeted therapy to treat motor neurone disease (MND) could be a turning point for patient care, after the results of a Phase 3 clinical trial showed significant ...
Aug. 30, 2022 — Researchers have developed the first mouse model for a mitochondrial tRNALeu mutation, showing that the associated metabolic disorder results from faulty RNA ...
June 22, 2022 — The immune system may play a fundamental role along with the central nervous system in amyotrophic lateral sclerosis (ALS), also known as 'Lou Gehrig's disease,' researchers ...
June 21, 2022 — Amyotrophic lateral sclerosis (ALS) is a progressive disease of the nervous system. It affects nerve cells in the brain and spinal cord called motor neurons. Motor neurons control muscle movement and ...
May 18, 2022 — New preclinical research on the experimental drug, NU-9, to treat ALS shows it is more effective than existing FDA-approved drugs for the disease. More importantly, NU-9 has an enhanced effect when ...
Mar. 29, 2022 — Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder that affects as many as 30,000 people in the United States, with 5,000 new cases diagnosed each year. It weakens muscles over time, ...
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- Investigational Drug for Genetic Form of ALS Improves Disease's Molecular Signs
- Promising MND Drug Helps Slow Disease Progression and Benefits Patients Physically