Amyotrophic Lateral Sclerosis News

November 7, 2025

Top Headlines

Scientists Just Found a Hidden Genetic Flaw That Slowly Steals Strength

Nov. 6, 2025 — A newly identified disorder, MINA syndrome, results from a mutation in the NAMPT protein that deprives motor neurons of energy, leading to severe movement problems. The discovery not only deepens understanding of nerve cell metabolism but also ...

Scientists Find Hidden Brain Source That Fuels Dementia

Nov. 6, 2025 — Weill Cornell researchers uncovered how free radicals from astrocyte mitochondria can fuel dementia. Using new compounds that target these radicals at their source, they slowed brain inflammation and neuronal damage in mice. The findings reveal a ...

Scientists Shocked to Find E. Coli Spreads as Fast as the Swine Flu

Nov. 4, 2025 — Researchers have, for the first time, estimated how quickly E. coli bacteria can spread between people — and one strain moves as fast as swine flu. Using genomic data from the UK and Norway, scientists modeled bacterial transmission rates and ...

Scientists Discover the Nutrient That Supercharges Cellular Energy

Nov. 3, 2025 — Scientists uncovered how the amino acid leucine enhances mitochondrial efficiency by preserving crucial proteins that drive energy production. By downregulating the protein SEL1L, leucine prevents unnecessary degradation and strengthens the cell’s ...

Breakthrough Blood Test Finally Confirms Chronic Fatigue Syndrome

Nov. 3, 2025 — A team of scientists has developed a highly accurate blood test for Chronic Fatigue Syndrome. The test reads tiny DNA patterns that reveal the biological signature of the illness. For millions who’ve faced doubt and misdiagnosis, it’s a ...

Alzheimer’s Might Be Powered by a Broken Sleep-wake Cycle

Nov. 3, 2025 — Disrupted sleep patterns in Alzheimer’s disease may be more than a symptom—they could be a driving force. Researchers at Washington University found that the brain’s circadian rhythms are thrown off in key cell types, changing when hundreds of ...

Scientists Find Hidden Antibiotic 100x Stronger Against Deadly Superbugs

Oct. 29, 2025 — A team of scientists discovered a hidden antibiotic 100 times stronger than existing drugs against deadly superbugs like MRSA. The molecule had been overlooked for decades in a familiar bacterium. It shows no signs of resistance so far, offering ...

From Poison to Power: How Lead Exposure Helped Shape Human Intelligence

Oct. 16, 2025 — Long before humans built cities or wrote words, our ancestors may have faced a hidden threat that shaped who we became. Scientists studying ancient teeth found that early humans, great apes, and even Neanderthals were exposed to lead millions of ...

Supercharged Vitamin K Could Help the Brain Heal Itself

Oct. 14, 2025 — Researchers have synthesized enhanced vitamin K analogues that outperform natural vitamin K in promoting neuron growth. The new compounds, which combine vitamin K with retinoic acid, activate the mGluR1 receptor to drive neurogenesis. They also ...

New Pill Could Finally Control Stubborn High Blood Pressure

Oct. 8, 2025 — A new pill called baxdrostat may offer hope for people whose blood pressure stays high even after taking standard medications. In a recent study, the drug lowered blood pressure and also seemed to protect the kidneys by reducing signs of damage. ...

Scientists Just Found Cancer Cells’ Hidden Power Source

Oct. 5, 2025 — When cancer cells are physically squeezed, they mount an instant, high-energy defense by rushing mitochondria to the cell nucleus, unleashing a surge of ATP that fuels DNA repair and survival. This newly discovered mechanism, visualized in real time ...

Hidden Cellular “Power Switch” Could Transform Parkinson’s Treatment

Oct. 4, 2025 — Researchers uncovered a key cellular regulator, PP2A-B55alpha, that controls both the cleanup of damaged mitochondria and the creation of new ones. In Parkinson’s disease models, reducing this regulator improved symptoms and mitochondrial health. ...

Latest Headlines

updated 11:20am EST

A Toxic Alzheimer’s Protein Could Be the Key to Fighting Cancer

Oct. 10, 2025 — A surprising link between Alzheimer’s and cancer reveals that amyloid beta, a harmful protein in the brain, actually empowers the immune system. It strengthens T-cells’ energy production, helping ...

Stunning Images Reveal How Antibiotics Shatter Bacterial Defenses

Sep. 29, 2025 — Researchers have revealed how polymyxins, crucial last-resort antibiotics, break down bacterial armor by forcing cells to overproduce and shed it. Astonishingly, the drugs only kill bacteria when ...

Brain Fat, Not Just Plaques, May Be the Hidden Driver of Alzheimer’s

Sep. 24, 2025 — For decades, scientists believed Alzheimer’s was driven mainly by sticky protein plaques and tangles in the brain. Now Purdue researchers have revealed a hidden culprit: fat. They found that brain ...

Hidden Brain Signal Reveals Alzheimer’s Years Before Symptoms

Sep. 22, 2025 — A new study has revealed that TSPO, a protein linked to brain inflammation, rises long before Alzheimer’s symptoms appear. Researchers tracked the protein in genetically engineered mice and ...

Your Nose Could Detect Alzheimer’s Years Before Memory Loss

Sep. 1, 2025 — Researchers have uncovered why smell often fades early in Alzheimer’s: the brain’s immune cells dismantle key nerve connections between the olfactory bulb and brainstem. Membrane changes in ...

Lithium Deficiency May Be the Hidden Spark Behind Alzheimer’s

Aug. 29, 2025 — Harvard scientists have uncovered that lithium, a naturally occurring element in the brain, may be the missing piece in understanding Alzheimer’s. Their decade-long research shows that lithium ...

Common Painkillers Like Advil and Tylenol Supercharge Antibiotic Resistance

Aug. 26, 2025 — Painkillers we often trust — ibuprofen and acetaminophen — may be quietly accelerating one of the world’s greatest health crises: antibiotic resistance. Researchers discovered that these drugs ...

Is Ketamine the Answer for Chronic Pain? New Findings Cast Doubt

Aug. 18, 2025 — A sweeping review of 67 trials has cast doubt on the use of ketamine and similar NMDA receptor antagonists for chronic pain relief. While ketamine is frequently prescribed off-label for conditions ...

Scientists Reversed Memory Loss by Powering the Brain’s Tiny Engines

Aug. 12, 2025 — Scientists have discovered a direct cause-and-effect link between faulty mitochondria and the memory loss seen in neurodegenerative diseases. By creating a novel tool to boost mitochondrial activity ...

Scientists Find Brain Cell Switch That Could Reverse Obesity’s Effects

Aug. 8, 2025 — High-fat diets and obesity reshape astrocytes—star-shaped brain cells in the striatum that help regulate pleasure from eating. French researchers discovered that tweaking these cells in mice not ...

New “evolution Engine” Creates Super-Proteins 100,000x Faster

Aug. 8, 2025 — Researchers at Scripps have created T7-ORACLE, a powerful new tool that speeds up evolution, allowing scientists to design and improve proteins thousands of times faster than nature. Using engineered ...

Breakthrough Lung Cancer Treatment Supercharges Immune Cells With Mitochondria

Aug. 3, 2025 — Scientists have found a way to supercharge lung cancer treatment by transplanting healthy mitochondria into tumors, which both boosts immune response and makes chemotherapy far more effective. By ...

This New Drug Could Help PTSD Patients Finally Let Go of Trauma

Aug. 3, 2025 — Researchers discovered that PTSD may be driven by excess GABA from astrocytes, not neurons. This chemical imbalance disrupts the brain’s ability to forget fear. A new drug, KDS2010, reverses this ...

Scientists Discover the Receptor That Helps Your Brain Clean Itself—and Fight Alzheimer’s

July 27, 2025 — Scientists at UCSF have uncovered how certain immune cells in the brain, called microglia, can effectively digest toxic amyloid beta plaques that cause Alzheimer’s. They identified a key receptor, ...

Three-Person DNA IVF Stops Inherited Disease—eight Healthy Babies Born in UK First

July 18, 2025 — In a groundbreaking UK first, eight healthy babies have been born using an IVF technique that includes DNA from three people—two parents and a female donor. The process, known as pronuclear ...

Parkinson’s Reversal? One Drug Brings Dying Brain Cells Back to Life

July 3, 2025 — Stanford researchers discovered that dialing down an overactive enzyme, LRRK2, can regrow lost cellular “antennae” in key brain cells, restoring vital dopamine communication and neuroprotective ...

Scientists Reverse Parkinson’s Symptoms in Mice — Could Humans Be Next?

July 5, 2025 — Scientists at the University of Sydney have uncovered a malfunctioning version of the SOD1 protein that clumps inside brain cells and fuels Parkinson’s disease. In mouse models, restoring the ...

How Brain Cells Meant to Help May Be Making Depression Worse

June 24, 2025 — Major depressive disorder affects hundreds of millions worldwide, but a key to understanding its origins may lie in the brain’s immune system. New findings spotlight astrocytes—previously ...

Invisible ID: How a Single Breath Could Reveal Your Health—and Your Identity

June 13, 2025 — Scientists have discovered that your breathing pattern is as unique as a fingerprint and it may reveal more than just your identity. Using a 24-hour wearable device, researchers achieved nearly 97% ...

Brain-Computer Interface Restores Real-Time Speech in ALS Patient

June 12, 2025 — A team at UC Davis has made a major leap in neurotechnology, enabling a man with ALS to speak again through a brain-computer interface that converts thoughts into speech in real time. Unlike prior ...

Brain Reboot: Gene Therapy Reverses Alzheimer’s Memory Loss in Mice

June 24, 2025 — UC San Diego scientists have created a gene therapy that goes beyond masking Alzheimer’s symptoms—it may actually restore brain function. In mice, the treatment protected memory and altered ...

Immune System Discovery Reveals Potential Solution to Alzheimer's

June 2, 2025 — A new way of thinking about Alzheimer's disease has yielded a discovery that could be the key to stopping the cognitive decline seen in Alzheimer's and other neurodegenerative diseases, ...

Research Untangles Role of Stress Granules in Neurodegenerative Disease

May 28, 2025 — Scientists found that stabilizing stress granules suppresses the effects of ALS-causing mutations, correcting previous models that imply stress granules promote amyloid ...

Mitochondrial DNA Mutation Accumulation May Not Be a Determining Factor in Aging

May 27, 2025 — Mutations accumulated in mitochondrial DNA associated with aging were earlier believed to cause aging by decreasing the energy-producing function (mitochondrial respiratory function). In this study, ...

Different Versions of APOE Protein Have Varying Effect on Microglia in Alzheimer's Disease

May 27, 2025 — A new study suggests how APOE2 is protective while APOE4 increases disease risk by regulating the brain's immune ...

Experimental Drug May Benefit Some Patients With Rare Form of ALS

May 23, 2025 — Some patients with a rare form of ALS benefited from an experimental therapy, with biomarker evidence of reduced injury to neurons and even limited functional ...

Scientists Design Gene Delivery Systems for Cells in the Brain and Spinal Cord

May 21, 2025 — Research teams have created a versatile set of gene delivery systems that can reach different neural cell types in the human brain and spinal cord with exceptional accuracy. These delivery systems ...

New Research on ALS Opens Up for Early Treatment

May 20, 2025 — Using the gene scissors CRISPR and stem cells, researchers have managed to identify a common denominator for different gene mutations that all cause the neurological disease ALS. The research shows ...

Maintaining Balance in the Immune System

May 19, 2025 — Researchers have published the first description of the role of the ZFP36 family of RNA binding proteins in regulatory T cells (Tregs). Tregs are key to maintaining balance in the immune system and ...

Sugar-Coated Nanotherapy Dramatically Improves Neuron Survival in Alzheimer's Model

May 14, 2025 — In many neurodegenerative diseases, proteins misfold and clump together in brain tissue. Scientists developed a new therapy made of peptides and a sugar that naturally occurs in plants. The ...