Sickle Cell Anemia News
April 19, 2024
Top Headlines
Jan. 29, 2024 — Researchers have revealed that hydroxyurea significantly reduces infections in children with sickle cell anemia. Their findings enhance strong evidence of hydroxyurea's effectiveness and could ...
Nov. 16, 2023 — Researchers have discovered that 'cell competition' following gene therapy results in the accumulation of stem cells with genetic mutations which make them grow faster. Some of these genetic mutations have been previously seen at higher levels in ...
Nov. 14, 2023 — A team has mapped the location and spatial features of blood-forming cells within human bone marrow. Their findings confirm hypotheses about the anatomy of this tissue and provide a powerful new means to study diseases, ranging from noncancerous ...
Aug. 30, 2023 — A clinical trial has tested a potentially curative stem cell gene therapy for sickle cell disease. The results were ...
Latest Headlines
updated 10:44pm EDT
Aug. 9, 2023 — A study shows new steps toward more patients getting gene ...
July 27, 2023 — In a step forward in the development of genetic medicines, researchers have developed a proof-of-concept model for delivering gene editing tools to ...
May 4, 2023 — A major challenge in human genetics is understanding which parts of the genome drive specific traits or contribute to disease risk. This challenge is ...
Apr. 17, 2023 — Scientists showed how prime editing can correct mutations that cause sickle cell disease in a potentially curative ...
Mar. 16, 2023 — While research has long established disparities in health outcomes among individuals living with sickle cell disease (SCD), few studies have ...
Oct. 24, 2022 — Researchers are working to reveal potential threats to the efficacy of CRISPR/Cas9 gene editing, even when it appears to be working as ...
Oct. 12, 2022 — Scientists found the cellular response to low oxygen also increases fetal hemoglobin expression in adults, which could lead to novel treatments for ...
Apr. 14, 2022 — Results from a phase 3 clinical indicate that the oral drug mitapivat is safe and effective for treating adults with pyruvate kinase deficiency, a ...
Apr. 8, 2022 — Researchers have used CRISPR gene editing -- a type of 'molecular scissors' -- to understand how deletions in one area of the genome can affect the ...
Feb. 16, 2022 — Sickle cell anemia is an inherited blood disorder where red blood cells become sickle/crescent shaped. It causes frequent infections, swelling in the hands and legs, pain, severe tiredness and ...
Earlier Headlines
Apr. 11, 2024 — A drug approved to treat pulmonary arterial hypertension may be effective at managing hypertension and end-organ damage in patients with sickle cell disease, according to a new study. An early phase ...
Jan. 30, 2023 — Researchers have designed a microfluidic device, or 'spleen-on-a-chip,' that can model how the spleen's filters become clogged by sickled red blood cells, leading to a life-threatening ...
Jan. 14, 2022 — A world-first study has revealed how space travel can cause lower red blood cell counts, known as space anemia. Analysis of 14 astronauts showed their bodies destroyed 54 percent more red blood cells ...
Dec. 13, 2021 — An experimental gene therapy for sickle cell disease restored blood cells to their normal shape and eliminated severe pain crises for years after treatment, a multicenter study has ...
Dec. 10, 2021 — Organ-on-a-chip technology has provided a push to discover new drugs for a variety of rare and ignored diseases for which current models either don't exist or lack precision. In particular, ...
Nov. 11, 2021 — Studying mice, researchers have developed a method of stem cell transplantation that does not require radiation or chemotherapy. Instead, the strategy takes an immunotherapeutic approach, combining ...
Sep. 21, 2021 — A multifaceted microfluidic in vitro assay is helping to identify the role of hypoxia on red blood cell aging via the biomechanical pathways. It holds promise for investigating hypoxic effects on the ...
Aug. 6, 2021 — Pooled results from phase 3 clinical trials demonstrate that roxadustat is efficacious and may be comparable to placebo in studies done to date for treating anemia in patients with chronic kidney ...
July 1, 2021 — New research finds that certain factors, such as a history of severe pain episodes and coexisting organ conditions, increase the risk of severe COVID-19 illness, including hospitalization, in ...
June 3, 2021 — Sickle cell disease leads to chronic pain, organ failure, and early death in patients worldwide. A team has demonstrated a gene editing approach that efficiently corrects the mutation underlying SCD ...
June 1, 2021 — Researchers have developed a proof-of-concept treatment for blood disorders like sickle cell disease and beta-thalassemia that could raise hemoglobin levels by activating production of both fetal and ...
May 6, 2021 — Scientists have developed a highly efficient method to address a major challenge in biology -- identifying the genetic 'switches' that regulate gene ...