Leukemia News

April 19, 2024

Top Headlines

Promising Drug Combination for Multiple Myeloma Treatment

Mar. 25, 2024 — New research has found that venetoclax, a medication currently approved for leukemia, has benefits for patients with multiple myeloma when used in combination with another drug. This discovery offers a new avenue of treatment options for the ...

An Immunotherapy to Overcome Resistant Leukemia

Mar. 21, 2024 — Researchers have discovered that a specific mutation in the cancer cells of an aggressive type of blood cancer can prevent novel immunotherapies such as CAR T-cell therapy from working. Their study also explains why the cancer cells are resistant ...

Skeleton-Wide Study of Blood Cell Formation Yields Surprising Findings

Mar. 20, 2024 — Imagine being able to count the different types of blood cells being formed inside the tiny bones of a mouse and pinpointing the strings and clusters of cells within the bone marrow that are responsible for producing specific types of blood cells. ...

Clues to Cancer Drug's Deadly Side Effects Could Make It Safer

Feb. 8, 2024 — For some leukemia patients, their only treatment option carries a risk of heart ...

Latest Headlines

updated 10:44pm EDT

Targeting Vulnerability in B-Cell Development Leads to Novel Drug Combination for Leukemia

Apr. 8, 2024 — Scientists discovered which tumor cells resist treatment and why. By characterizing B-cells' developmental stages, they designed and tested a drug ...

Targeting RAS Proteins May Prevent Relapse in Acute Myeloid Leukemia

Apr. 9, 2024 — Relapses in a common form of leukemia may be preventable following new research that has identified how the cancer develops resistance to first line ...

How Gene Activity Modulates the Amount of Immune Cell Production in Mice

Jan. 26, 2024 — Researchers describe how specific gene activity could potentially enhance immune cell production. The researchers wanted to understand the mechanism of why some hematopoietic stem cells produce more ...

HOXA9 Tracking Reveals RBM5 Dual Function and Therapeutic Potential for Acute Myeloid Leukemia

Jan. 13, 2024 — Using CRISPR/Cas9, scientists identified RBM5 as a vital component of leukemia cell fitness, making it a promising target for drug ...

Researchers Discover Compound That Fights Leukemia, Lymphoma

Jan. 13, 2024 — Researchers have identified a novel pharmaceutical compound that successfully kills leukemia and lymphoma cancer cells, potentially paving the way for new forms of ...

Leukemia: Artificial Intelligence Provides Support in Diagnostics

Jan. 9, 2024 — Decisions on treatment for leukemia patients are based, among other things, on a series of certain genetic features of the disease. IT specialists and physicians have now shown how a method based on ...

'Exceptional' Results in Phase III Leukemia Trial

Dec. 10, 2023 — Leukaemia trial shows 'exceptional' results. Personalized treatment for the most common form of adult leukemia helps patients survive for longer and stay in remission, a phase III trial has found. ...

Leukemia Cells Activate Cellular Recycling Program

Dec. 4, 2023 — To speed up their growth, leukemia cells typically activate the recycling of cellular structures -- enabling them to dispose of defective components and better supply themselves with building ...

Promising Target for CAR T Cells Helps Cancer Trick the Immune System

Nov. 21, 2023 — GRP78 is a promising CAR T-cell immunotherapy target for brain and solid tumors. Discover why it's special, including how cancer uses it to trick immune ...

Pediatric Oncology: Scientists Discover New Achilles Heel of Leukemia Cells

Nov. 22, 2023 — Leukemia is the most common type of cancer in children. Treatment involves intensive chemotherapy, which has severe side effects due to its non-specific mode of action. A team has now discovered a ...

Molecule Can Quickly, and Briefly, Boost White Blood Cell Counts

Jan. 31, 2024 — Treatment with a molecule known as A485 can quickly and temporarily increase levels of white blood cells, a critical part of the body's immune system, an effect that is difficult to deliver with ...

The Hidden Identity of Leukemia

Jan. 9, 2024 — Researchers used various sequencing technologies to explore the molecular characteristics of myeloid/natural killer cell precursor acute leukemia (MNKPL). They observed activation of the NOTCH1 and ...

Researchers Chart the Contents of Human Bone Marrow

Nov. 14, 2023 — A team has mapped the location and spatial features of blood-forming cells within human bone marrow. Their findings confirm hypotheses about the anatomy of this tissue and provide a powerful new ...

Dietary Supplement Modifies Gut Microbiome -- Potential Implications for Bone Marrow Transplant Patients

Oct. 20, 2023 — Researchers conducted a phase I pilot study to assess the feasibility of using potato starch as a dietary intervention to modify the gut microbiome in bone marrow transplant patients. The study is ...

Expanding the Impact of CAR T Cell Therapy: An Immunotherapy Strategy Against All Blood Cancers

Aug. 31, 2023 — A broad new strategy could hold hope for treating virtually all blood cancers with CAR T cell therapy, which is currently approved for five subtypes of blood cancer. Scientists have demonstrated the ...

Drug That Targets Scar-Like Tissue in Tumors Shows Promise for Aggressive Pancreatic Cancer

Aug. 29, 2023 — Early laboratory results in mice show the drug PXS-5505 increases survival when combined with chemotherapy in the treatment of pancreatic ductal ...

How TET2 Gene Deficiency Fuels Development of Acute Myeloid Leukemia

Aug. 17, 2023 — Scientists have identified how low levels of the TET2 gene fuel the rapid growth of acute myeloid leukemia in animal ...

Research Raises Hopes for New Treatment of Fusion-Driven Cancer

Aug. 11, 2023 — Researchers have developed a new form of gene therapy that can stop cell division in fusion-driven ...

Research Sheds New Light on Gene Therapy for Blood Disorders

Aug. 9, 2023 — A study shows new steps toward more patients getting gene ...

Demonstration of Safety of Microbiota Transplant Therapy in Stem Cell Transplant and Leukemia Patients

July 6, 2023 — A new study has demonstrated the safety of using microbiota transplant therapy (MTT) in patients with acute myeloid leukemia (AML) -- a type of blood cancer -- and recipients of hematopoietic cell ...

Study Sets New Standard for Graft-Versus-Host Disease Prevention After Stem Cell Transplant

June 22, 2023 — Clinicians have a new standard for graft-versus-host disease (GVHD) prevention after allogeneic hematopoietic stem cell transplantation, according to results from a phase III study. The new standard ...

Further Hope for Base-Edited T-Cell Therapy to Treat Resistant Leukemia

June 14, 2023 — Three young patients with relapsed T-cell leukemia have now been treated with base-edited ...

'Revolutionary' Research Discovers New Cause of Cancer Coming from Inside Us

June 8, 2023 — Cancer researchers have made an important new connection between a person's cancer risk and the activity of circular RNAs, a poorly understood family of genetic fragments present in the body. A ...

Drug Combination Restores Ability of Leading Treatment to Signal for Death of Blood Cancer Cells

Apr. 24, 2023 — Despite the promise of new medications that promote cancer cell death in people with acute myeloid leukemia, leukemic cells often adopt features that let them evade the drugs' effects within a ...

Why Does a Leukemic Mutation Not Always Lead to Leukemia?

Mar. 23, 2023 — Scientists have discovered a mechanism that linked a leukemic mutation to varying potentials for disease development -- a discovery which could eventually lead to a way to identify patients with the ...

What Makes Blood Stem Cells Transform? Regulation of RNA Splicing May Be an Answer

Mar. 21, 2023 — Researchers have determined a novel mechanism linking the metabolism of ribonucleic acids, RNA, to the development of leukemia in myelodysplastic syndrome patients, MDS. They explain what makes ...

Study Unravels a Cause of Resistance to Novel Drug in Patients With Acute Leukemia

Mar. 15, 2023 — A new targeted drug has not only sparked remissions in patients with a common form of leukemia but also induced the cancer cells to reveal one of their schemes for resisting the drug, investigators ...

Cause of Leukemia in Trisomy 21

Mar. 10, 2023 — People with a third copy of chromosome 21, known as trisomy 21, are at high risk of developing acute myeloid leukemia (AML), an aggressive form of blood cancer. Scientists have now identified the ...

Seeking Leukemia's Achilles Heel

Mar. 8, 2023 — Researchers identify potential therapeutic for acute myeloid leukemia that targets a DNA repair ...

New Promising Targeted Drug for a Rare Leukemia

Feb. 23, 2023 — Researchers have identified a possible new targeted drug for treating acute myeloid leukemia. In the future, the discovery may help patients with certain rare subtypes of the ...