Restless Leg Syndrome News

December 5, 2025

Top Headlines

Alzheimer’s Blood Tests May Be Misleading for People with Kidney Problems

Dec. 5, 2025 A large study found that people with impaired kidneys tend to have higher Alzheimer’s biomarkers, yet they don’t face a higher overall risk of dementia. For those who already have elevated biomarkers, kidney problems may speed up when symptoms ...

A Drug Already in Trials May Stop Chemotherapy Nerve Damage

Nov. 21, 2025 Researchers discovered that chemotherapy can accidentally trigger a stress alarm in immune cells, causing inflammation that damages nerves. Blocking this alarm protected mice from nerve pain and kept their nerves healthier. A drug already being ...

Nearly 47 Million Americans Live Near Hidden Fossil Fuel Sites

Nov. 20, 2025 A nationwide analysis has uncovered how sprawling fossil fuel infrastructure sits surprisingly close to millions of American homes. The research shows that 46.6 million people live within about a mile of wells, refineries, pipelines, storage sites, ...

A Silent Kidney Crisis Is Spreading Faster Than Anyone Expected

Nov. 18, 2025 Chronic kidney disease has surged to nearly 800 million cases and is now among the top causes of death worldwide. The condition is heavily linked to diabetes, hypertension, and obesity, and often goes unnoticed until late stages. Many countries lack ...

A Groundbreaking Brain Map Could Revolutionize Parkinson’s Treatment

Nov. 3, 2025 Duke-NUS scientists unveiled BrainSTEM, a revolutionary single-cell map that captures the full cellular diversity of the developing human brain. The project’s focus on dopamine neurons provides crucial insight for Parkinson’s treatment. Their ...

New Pill Could Finally Control Stubborn High Blood Pressure

Oct. 8, 2025 A new pill called baxdrostat may offer hope for people whose blood pressure stays high even after taking standard medications. In a recent study, the drug lowered blood pressure and also seemed to protect the kidneys by reducing signs of damage. ...

Hidden Gut Molecule Found to Wreck Kidneys

Sep. 12, 2025 Scientists discovered that a gut bacteria molecule called corisin can travel to the kidneys, triggering inflammation and scarring that lead to diabetic kidney fibrosis. By attaching to albumin in the blood, corisin infiltrates kidney tissue and ...

Overworked Neurons Burn Out and Fuel Parkinson’s Disease

Sep. 3, 2025 Overactivation of dopamine neurons may directly drive their death, explaining why movement-controlling brain cells degenerate in Parkinson’s. Mice with chronically stimulated neurons showed the same selective damage seen in patients, along with ...

Why Trump’s Leg Swelling Could Be a Warning Sign for Millions

July 18, 2025 President Trump s diagnosis of Chronic Venous Insufficiency (CVI) has brought renewed attention to a frequently overlooked yet dangerous condition. CVI affects the ability of veins especially in the legs to return blood to the heart, often leading ...

Parkinson’s Reversal? One Drug Brings Dying Brain Cells Back to Life

July 3, 2025 Stanford researchers discovered that dialing down an overactive enzyme, LRRK2, can regrow lost cellular “antennae” in key brain cells, restoring vital dopamine communication and neuroprotective signals in a mouse model of genetic Parkinson’s. ...

Chronic Renal Failure: Discovery of a Crucial Biomarker

May 27, 2025 Scientists have identified microRNA able to protect small blood vessels and support kidney function after severe ...

Antidepressant Withdrawal Symptoms More Common Among Long-term Users

May 26, 2025 People who have been taking antidepressants for more than two years are substantially more likely to experience withdrawal symptoms compared to short-term users when they come off the medication, finds a new ...

Latest Headlines

updated 9:10am EST

Scientists Reverse Kidney Damage in Mice, Hope for Humans Next

Nov. 14, 2025 Researchers uncovered how fatty molecules called ceramides trigger acute kidney injury by damaging the mitochondria that power kidney cells. By altering ceramide metabolism or using a new drug ...

Common Antidepressants Could Help the Immune System Fight Cancer

May 22, 2025 SSRIs boosted the ability of T cells to kill cancer cells and suppressed tumor growth in both mouse and human tumor ...

Hand2: Positional Code That Allows Axolotls to Regrow Limbs Found

May 22, 2025 With its fascinating ability to regrow entire limbs and internal organs, the Mexican axolotl is the ideal model for studying regeneration. Scientists have now found a factor that tells cells which ...

Experimental Painkiller Could Outsmart Opioids -- Without the High

May 19, 2025 A breakthrough drug from Duke University, SBI-810, promises strong pain relief without the pitfalls of opioids. Unlike traditional painkillers that trigger multiple brain pathways—and often ...

Patients With Glioblastoma Who Received Gabapentin Lived Longer, Study Suggests

May 16, 2025 A new study suggests that gabapentin, a relatively common anti-seizure/pain medication, is linked to improved survival in patients with glioblastoma ...

Scientists Discover New Way the Brain Learns

May 14, 2025 Neuroscientists have discovered that the brain uses a dual system for learning through trial and error. This is the first time a second learning system has been identified, which could help explain ...

Groundbreaking Device Instantly Detects Dangerous Street Drugs, Offering Hope for Harm Reduction

May 7, 2025 Groundbreaking device instantly detects dangerous street drugs, offering hope for harm reduction A portable device that instantly detects illicit ...

Mechanism by Which the Brain Weighs Positive Vs. Negative Social Experience Is Revealed

May 2, 2025 Researchers have identified the neural mechanisms in the brain that regulate both positive and negative impressions of a social encounter, as well as ...

How Disturbed Signaling Pathways Could Promote Epileptic Seizures

Apr. 16, 2025 Focal cortical dysplasia (FCD) type 2 is a congenital malformation of the cerebral cortex that is often associated with difficult-to-treat epilepsy. In the affected areas, nerve cells and their layer ...

What Links Cannabis Use and Psychosis? Researchers Point to Brain's Dopamine System

Apr. 11, 2025 A new study found that people with cannabis use disorder (CUD) had elevated dopamine levels in a brain region associated with ...

Researchers Identify Precision Medicine Approach for Preventing Kidney Failure

Apr. 9, 2025 Researchers have identified type 5 collagen as a key factor in kidney fibrosis, revealing its potential as a biomarker to predict chronic kidney disease progression. A repurposed anti-cancer drug, ...

Groundbreaking Study Reveals Changes in Brain Cell Composition and Gene Activity in Tourette Syndrome

Apr. 8, 2025 In the first comprehensive, cell-by-cell analysis of brain tissue from individuals with Tourette syndrome, researchers have pinpointed exactly which cells are perturbed and how they malfunction, ...

PET Imaging Confirms Direct Involvement of Dopamine in Cognitive Flexibility

Mar. 28, 2025 Scientists have confirmed a neurobiochemical link between dopamine and cognitive flexibility. PET imaging shows that the brain increases dopamine production when completing cognitively demanding ...

Scientists Discover Why Obesity Takes Away the Pleasure of Eating

Mar. 26, 2025 Why do some people lose the joy of eating, even when surrounded by irresistible foods? UC Berkeley researchers have uncovered a surprising brain mechanism that explains this paradox. They found that ...

Dopamine's Unexpected Role in Memory Devaluation

Mar. 12, 2025 New research expands on current understanding of the brain chemical dopamine, finding that it plays a role in reducing the value of memories associated with rewards. The study opens new avenues for ...

Clinical Trial Tests Novel Stem-Cell Treatment for Parkinson's Disease

Mar. 9, 2025 A recently launched Phase 1 clinical trial is examining the safety and feasibility of a groundbreaking treatment approach for Parkinson's disease in which a patient's stem cells are ...

Antidepressants Linked to Faster Cognitive Decline in Dementia, Study Suggests

Feb. 25, 2025 New research suggests that certain antidepressants can accelerate cognitive decline in people with dementia. At the same time, some drugs appear to be less harmful than others, which can help doctors ...

Co-Prescribed Stimulants, Opioids Linked to Higher Opioid Doses

Feb. 21, 2025 The combination of prescribed central nervous system stimulants, such as drugs that relieve ADHD symptoms, with prescribed opioid medications is associated with a pattern of escalating opioid intake, ...

A New Treatment for Post-Amputation Pain?

Feb. 19, 2025 War study in Ukraine suggests hydrodissection may reduce pain, opioid use in ...

Researchers Create Genetic Map Tied to Kidney Disease

Feb. 11, 2025 Over 1,000 genes may serve as possible treatment targets for individuals with kidney disease, according to a new study. By creating the most complete and detailed genetic 'map' of kidney ...

Music Makes Us Move Even When We Don't Like It

Feb. 11, 2025 The pleasurable urge to move to music -- to groove -- appears to be a physiological response independent of how much we generally enjoy music, according to a new article. That groove response is so ...

How Do You Treat Rotator-Cuff Tears?

Feb. 3, 2025 For those over 40, it's a common injury with different treatment options to ...

Fighting Experience Plays Key Role in Brain Chemical's Control of Male Aggression

Jan. 22, 2025 Like humans, mice will compete over territory and mates, and show increased confidence in their fighting skills the more they win. At first, a brain chemical called dopamine is essential for young ...

Non-Opioid Pain Relievers Beat Opioids After Dental Surgery

Jan. 6, 2025 Researchers find an over-the-counter combo is more effective for wisdom tooth extraction ...

Integrating GABA and Dopamine Signals to Regulate Meal Initiation

Dec. 20, 2024 When you are feeling hungry, the brain takes the necessary steps toward consuming a meal. Many of these steps are not well known, but a new study reveals brain circuits and chemical messengers that ...

Antidepressants May Act in Gut to Reduce Depression and Anxiety

Dec. 11, 2024 In animal studies, boosting serotonin in the cells that line the gut reduced anxious and depressive-like behaviors without causing cognitive or gastrointestinal side ...

First Full Characterization of Kidney Microbiome Unlocks Potential to Prevent Kidney Stones

Dec. 11, 2024 Researchers have found definitive proof of a kidney microbiome that influences renal health and kidney stone formation, demonstrating that the urinary tract is not sterile and low levels of bacteria ...

'Missing Link' Between Brain and Body Inflammatory Signals Identified in the Skull

Dec. 9, 2024 New research provides valuable insights into the brain-body immune connection identifying key communication hubs in the dural sinuses and skull bone marrow at the back of the ...

Scientists Identify a Probable Contributor to Weakness of the Aorta in People With Genetic Disorder

Dec. 9, 2024 Studying the cells of people and genetically engineered mice, scientists say they have uncovered a potential reason why patients with Loeys-Dietz syndrome, an inherited connective tissue disorder, ...

Reducing Risk of Opioid Addiction While Alleviating Pain

Dec. 2, 2024 Increasing the levels of chemicals naturally produced in the body called endocannabinoids may thwart the highly addictive nature of opioids such as morphine and oxycodone while maintaining the ...