Restless Leg Syndrome News

September 15, 2025

Top Headlines

Hidden Gut Molecule Found to Wreck Kidneys

Sep. 12, 2025 — Scientists discovered that a gut bacteria molecule called corisin can travel to the kidneys, triggering inflammation and scarring that lead to diabetic kidney fibrosis. By attaching to albumin in the blood, corisin infiltrates kidney tissue and ...

Overworked Neurons Burn Out and Fuel Parkinson’s Disease

Sep. 3, 2025 — Overactivation of dopamine neurons may directly drive their death, explaining why movement-controlling brain cells degenerate in Parkinson’s. Mice with chronically stimulated neurons showed the same selective damage seen in patients, along with ...

Why Trump’s Leg Swelling Could Be a Warning Sign for Millions

July 18, 2025 — President Trump s diagnosis of Chronic Venous Insufficiency (CVI) has brought renewed attention to a frequently overlooked yet dangerous condition. CVI affects the ability of veins especially in the legs to return blood to the heart, often leading ...

Parkinson’s Reversal? One Drug Brings Dying Brain Cells Back to Life

July 3, 2025 — Stanford researchers discovered that dialing down an overactive enzyme, LRRK2, can regrow lost cellular “antennae” in key brain cells, restoring vital dopamine communication and neuroprotective signals in a mouse model of genetic Parkinson’s. ...

Chronic Renal Failure: Discovery of a Crucial Biomarker

May 27, 2025 — Scientists have identified microRNA able to protect small blood vessels and support kidney function after severe ...

Antidepressant Withdrawal Symptoms More Common Among Long-term Users

May 26, 2025 — People who have been taking antidepressants for more than two years are substantially more likely to experience withdrawal symptoms compared to short-term users when they come off the medication, finds a new ...

Common Antidepressants Could Help the Immune System Fight Cancer

May 22, 2025 — SSRIs boosted the ability of T cells to kill cancer cells and suppressed tumor growth in both mouse and human tumor ...

Hand2: Positional Code That Allows Axolotls to Regrow Limbs Found

May 22, 2025 — With its fascinating ability to regrow entire limbs and internal organs, the Mexican axolotl is the ideal model for studying regeneration. Scientists have now found a factor that tells cells which part of the arm to regenerate -- and used it to ...

Experimental Painkiller Could Outsmart Opioids -- Without the High

May 19, 2025 — A breakthrough drug from Duke University, SBI-810, promises strong pain relief without the pitfalls of opioids. Unlike traditional painkillers that trigger multiple brain pathways—and often addiction—SBI-810 activates just one specific pathway ...

Patients with Glioblastoma Who Received Gabapentin Lived Longer, Study Suggests

May 16, 2025 — A new study suggests that gabapentin, a relatively common anti-seizure/pain medication, is linked to improved survival in patients with glioblastoma (GBM) -- the most common and deadly form of brain ...

Scientists Discover New Way the Brain Learns

May 14, 2025 — Neuroscientists have discovered that the brain uses a dual system for learning through trial and error. This is the first time a second learning system has been identified, which could help explain how habits are formed and provide a scientific ...

Groundbreaking Device Instantly Detects Dangerous Street Drugs, Offering Hope for Harm Reduction

May 7, 2025 — Groundbreaking device instantly detects dangerous street drugs, offering hope for harm reduction A portable device that instantly detects illicit street drugs at very low concentrations, thereby ...

Latest Headlines

updated 9:47am EDT

Mechanism by Which the Brain Weighs Positive Vs. Negative Social Experience Is Revealed

May 2, 2025 — Researchers have identified the neural mechanisms in the brain that regulate both positive and negative impressions of a social encounter, as well as ...

How Disturbed Signaling Pathways Could Promote Epileptic Seizures

Apr. 16, 2025 — Focal cortical dysplasia (FCD) type 2 is a congenital malformation of the cerebral cortex that is often associated with difficult-to-treat epilepsy. In the affected areas, nerve cells and their layer ...

What Links Cannabis Use and Psychosis? Researchers Point to Brain's Dopamine System

Apr. 11, 2025 — A new study found that people with cannabis use disorder (CUD) had elevated dopamine levels in a brain region associated with ...

Researchers Identify Precision Medicine Approach for Preventing Kidney Failure

Apr. 10, 2025 — Researchers have identified type 5 collagen as a key factor in kidney fibrosis, revealing its potential as a biomarker to predict chronic kidney ...

Groundbreaking Study Reveals Changes in Brain Cell Composition and Gene Activity in Tourette Syndrome

Apr. 8, 2025 — In the first comprehensive, cell-by-cell analysis of brain tissue from individuals with Tourette syndrome, researchers have pinpointed exactly which ...

PET Imaging Confirms Direct Involvement of Dopamine in Cognitive Flexibility

Mar. 28, 2025 — Scientists have confirmed a neurobiochemical link between dopamine and cognitive flexibility. PET imaging shows that the brain increases dopamine ...

Scientists Discover Why Obesity Takes Away the Pleasure of Eating

Mar. 26, 2025 — Many obese people report losing pleasure in eating rich foods -- something also seen in obese mice. Scientists have now discovered the reason. Long-term high-fat diets lower levels of neurotensin in ...

Dopamine's Unexpected Role in Memory Devaluation

Mar. 14, 2025 — New research expands on current understanding of the brain chemical dopamine, finding that it plays a role in reducing the value of memories associated with rewards. The study opens new avenues for ...

Clinical Trial Tests Novel Stem-Cell Treatment for Parkinson's Disease

Mar. 9, 2025 — A recently launched Phase 1 clinical trial is examining the safety and feasibility of a groundbreaking treatment approach for Parkinson's disease in which a patient's stem cells are reprogrammed to ...

Antidepressants Linked to Faster Cognitive Decline in Dementia, Study Suggests

Feb. 28, 2025 — New research suggests that certain antidepressants can accelerate cognitive decline in people with dementia. At the same time, some drugs appear to ...

Co-Prescribed Stimulants, Opioids Linked to Higher Opioid Doses

Feb. 21, 2025 — The combination of prescribed central nervous system stimulants, such as drugs that relieve ADHD symptoms, with prescribed opioid medications is associated with a pattern of escalating opioid intake, ...

A New Treatment for Post-Amputation Pain?

Feb. 19, 2025 — War study in Ukraine suggests hydrodissection may reduce pain, opioid use in ...

Researchers Create Genetic Map Tied to Kidney Disease

Feb. 11, 2025 — Over 1,000 genes may serve as possible treatment targets for individuals with kidney disease, according to a new study. By creating the most complete and detailed genetic 'map' of kidney ...

Music Makes Us Move Even When We Don't Like It

Feb. 11, 2025 — The pleasurable urge to move to music -- to groove -- appears to be a physiological response independent of how much we generally enjoy music, according to a new article. That groove response is so ...

How Do You Treat Rotator-Cuff Tears?

Feb. 3, 2025 — For those over 40, it's a common injury with different treatment options to ...

Fighting Experience Plays Key Role in Brain Chemical's Control of Male Aggression

Jan. 22, 2025 — Like humans, mice will compete over territory and mates, and show increased confidence in their fighting skills the more they win. At first, a brain chemical called dopamine is essential for young ...

Non-Opioid Pain Relievers Beat Opioids After Dental Surgery

Jan. 6, 2025 — Researchers find an over-the-counter combo is more effective for wisdom tooth extraction ...

Integrating GABA and Dopamine Signals to Regulate Meal Initiation

Dec. 20, 2024 — When you are feeling hungry, the brain takes the necessary steps toward consuming a meal. Many of these steps are not well known, but a new study reveals brain circuits and chemical messengers that ...

Antidepressants May Act in Gut to Reduce Depression and Anxiety

Dec. 11, 2024 — In animal studies, boosting serotonin in the cells that line the gut reduced anxious and depressive-like behaviors without causing cognitive or gastrointestinal side ...

First Full Characterization of Kidney Microbiome Unlocks Potential to Prevent Kidney Stones

Dec. 11, 2024 — Researchers have found definitive proof of a kidney microbiome that influences renal health and kidney stone formation, demonstrating that the urinary tract is not sterile and low levels of bacteria ...

'Missing Link' Between Brain and Body Inflammatory Signals Identified in the Skull

Dec. 9, 2024 — New research provides valuable insights into the brain-body immune connection identifying key communication hubs in the dural sinuses and skull bone marrow at the back of the ...

Scientists Identify a Probable Contributor to Weakness of the Aorta in People With Genetic Disorder

Dec. 9, 2024 — Studying the cells of people and genetically engineered mice, scientists say they have uncovered a potential reason why patients with Loeys-Dietz syndrome, an inherited connective tissue disorder, ...

Reducing Risk of Opioid Addiction While Alleviating Pain

Dec. 2, 2024 — Increasing the levels of chemicals naturally produced in the body called endocannabinoids may thwart the highly addictive nature of opioids such as morphine and oxycodone while maintaining the ...

Nov. 26, 2024 — The biggest and most comprehensive analysis of glucagon-like peptide-1 (GLP-1) receptor agonists on kidney and cardiovascular outcomes shows they have significant benefits in people with and without ...

Discovery Explains Kidney Damage Caused by Blood Pressure Drugs

Nov. 21, 2024 — Scientists have discovered how long-term treatment of high blood pressure with commonly prescribed drugs can destroy the kidney's ability to filter and purify blood. The finding could open the ...

New Guideline Provides Treatment Recommendations for Restless Legs Syndrome

Nov. 13, 2024 — A new clinical practice guideline provides updated recommendations for the treatment of restless legs syndrome. The guideline reflects the latest scientific evidence and recommends significant ...

Developing Kidneys from Scratch

Oct. 28, 2024 — Researches made major strides toward the creation of artificial kidney tissue by demonstrating an undiscovered mechanism behind kidney development and a novel technique for culturing kidney cells, ...

Genomic Variants That Increase Risk of Kidney Disease Are Found in Nearly One-Third of West Africans

Oct. 28, 2024 — A study has revealed a significant genetic risk factor for kidney disease in people from Ghana and Nigeria. Their study demonstrated that having just one risk variant in a gene known as APOL1 can ...

Opioids May Negatively Impact Hormone Health

Oct. 24, 2024 — A new scientific statement released today by the Endocrine Society highlights research gaps associated with the negative effects of opioid use on the endocrine ...

Implantable Device May Prevent Death from Opioid Overdose

Oct. 23, 2024 — A team has developed a device that may rescue people from overdose without bystander help. In animal studies, the researchers found that the implantable device detects an overdose, rapidly delivers ...