Controlled Substances News

September 15, 2025

Top Headlines

Cannabis Use May Quadruple Diabetes Risk

Sep. 14, 2025 — A massive study of over 4 million adults has revealed that cannabis use may nearly quadruple the risk of developing diabetes. Despite some earlier suggestions that cannabis might have metabolic benefits, this large analysis found significantly ...

Don’t Toss Cannabis Leaves. Scientists Just Found Rare Compounds Inside

Sep. 10, 2025 — Scientists at Stellenbosch University have uncovered a rare class of plant compounds, flavoalkaloids, in Cannabis leaves for the first time. Using advanced two-dimensional chromatography and mass spectrometry, they identified 79 phenolic compounds ...

Overworked Neurons Burn Out and Fuel Parkinson’s Disease

Sep. 3, 2025 — Overactivation of dopamine neurons may directly drive their death, explaining why movement-controlling brain cells degenerate in Parkinson’s. Mice with chronically stimulated neurons showed the same selective damage seen in patients, along with ...

Study Finds Cannabis Improves Sleep Where Other Drugs Fail

Sep. 2, 2025 — A long-term study following insomnia patients treated with cannabis-based medical products revealed sustained improvements in sleep quality, mood, and pain management over 18 months. Most participants reported better rest and less anxiety or ...

Stronger Weed, Higher Risk? Potent THC Linked to Psychosis and Addiction

Sep. 2, 2025 — A sweeping review of nearly 100 studies has raised concerns about the mental health impacts of high-potency cannabis products. Researchers found strong links to psychosis, schizophrenia, and cannabis use disorder, while results for anxiety and ...

Cannabis for Coping? Why It May Trigger Paranoia

Aug. 28, 2025 — Using cannabis to self-medicate comes with hidden dangers—new research shows these users face higher paranoia and consume more THC. Childhood trauma further amplifies the risks, especially emotional abuse, which strongly predicts ...

The Hidden Mental Health Danger in Today’s High-THC Cannabis

Aug. 12, 2025 — THC levels in cannabis have soared in recent years, raising the risk of psychosis—especially in young, frequent users. Studies reveal a strong connection between cannabis-induced psychosis and schizophrenia, making early cessation and treatment ...

Unwanted Pregnancies Surge with Alcohol, but Not with Cannabis, Study Finds

Aug. 1, 2025 — Women who drank heavily, even though they strongly wished to avoid pregnancy, were 50% more likely to become pregnant than those who drank little or not at all, according to new research. Surprisingly, cannabis use didn t show the same ...

People with Eating Disorders Say Cannabis and Psychedelics Help More Than Antidepressants

July 24, 2025 — A massive global survey has revealed that people with eating disorders often turn to cannabis and psychedelics like magic mushrooms and LSD to ease their symptoms, rating them more effective than ...

Magic Mushrooms Rewind Aging in Mice—could They Do the Same for Humans?

July 22, 2025 — A surprising discovery from Emory University shows that psilocin, the active metabolite of psychedelic mushrooms, can delay cellular aging and extend lifespan. Human cells lived over 50% longer, and mice treated with psilocybin not only lived 30% ...

Parkinson’s Reversal? One Drug Brings Dying Brain Cells Back to Life

July 3, 2025 — Stanford researchers discovered that dialing down an overactive enzyme, LRRK2, can regrow lost cellular “antennae” in key brain cells, restoring vital dopamine communication and neuroprotective signals in a mouse model of genetic Parkinson’s. ...

Synthetic Storm: What’s Really in Your Teen’s Vape — And Why Scientists Are Alarmed

July 1, 2025 — Teen vaping is changing fast — and not in a good way. A large national study found that more adolescents are vaping THC, CBD, and especially synthetic cannabinoids, which are often unregulated and ...

Latest Headlines

updated 10:19am EDT

Found in the Trash: A Super Opioid 1000x Stronger Than Morphine

Aug. 1, 2025 — A powerful new synthetic opioid, up to 1000 times stronger than morphine, has emerged in Adelaide’s street drug supply, and researchers are sounding the alarm. Nitazenes, often hidden in heroin or ...

Candy Colors, THC Inside: How Cannabis Edibles Are Tricking Teen Brains

June 28, 2025 — Teens are being misled by cannabis edibles dressed up like health foods. Bright colors, fruit imagery, and words like vegan make these products look fun, natural, and safe even when they re not. A ...

Cannabis Use Among Seniors Surges 46% in Two Years--Study Reveals

June 7, 2025 — Cannabis use among older Americans has climbed dramatically, with 7% of adults 65 and older now reporting recent use. This rise isn't just in numbers but also in diversity older users today are more ...

Clinical Research on Psychedelics Gets a Boost from New Study

June 3, 2025 — As psychedelics gain traction as potential treatments for mental health disorders, an international study stands to improve the rigor and reliability of clinical ...

Record High: Study Finds Growing Cannabis Use Among Older Adults

June 3, 2025 — Marijuana use among older adults in the US has reached a new high, with 7 percent of adults aged 65 and over who report using it in the past month, according to a recent ...

Whether It's Smoking or Edibles, Marijuana Can Be Bad for Your Heart, Study Suggests

May 28, 2025 — A new study finds that chronic cannabis use -- whether it's smoked or consumed in edible form -- is associated with significant cardiovascular ...

Nearly Five Million Seized Seahorses Just 'Tip of the Iceberg' in Global Wildlife Smuggling

May 28, 2025 — Close to five million smuggled seahorses worth an estimated CAD$29 million were seized by authorities over a 10-year span, according to a new study ...

Tiny Genetic Switch Found to Control Brain Balance and Behavior

May 26, 2025 — Researchers have identified a remarkably small but critical piece of genetic code that helps determine how brain cells connect, communicate, and function. The discovery not only deepens our ...

A Potential 'Anti-Spice' That Could Dial Down the Heat of Fiery Food

May 22, 2025 — If you've ever regretted ordering a spicy meal, take note: A new study identifying molecules that suppress the heat of chili peppers hints at the possibility of adapting these compounds into an ...

Scientists Discover New Way the Brain Learns

May 14, 2025 — Neuroscientists have discovered that the brain uses a dual system for learning through trial and error. This is the first time a second learning system has been identified, which could help explain ...

AI-Designed DNA Controls Genes in Healthy Mammalian Cells for First Time

May 8, 2025 — A recent study marks the first reported instance of generative AI designing synthetic molecules that can successfully control gene expression in healthy mammalian cells. As a proof-of-concept, the ...

Groundbreaking Device Instantly Detects Dangerous Street Drugs, Offering Hope for Harm Reduction

May 7, 2025 — Groundbreaking device instantly detects dangerous street drugs, offering hope for harm reduction A portable device that instantly detects illicit street drugs at very low concentrations, thereby ...

Cannabis Study: Legalization Reduces Problematic Consumption, Particularly Among Certain Individuals

May 7, 2025 — Researchers are investigating how the legal supply of cannabis affects consumption and mental health among participants. In a first academic publication, the study team has now reported on the direct ...

Evidence Review Raises Concern About Cannabis Use in Pregnancy

May 5, 2025 — A systematic evidence review finds that consuming cannabis while pregnant appears to increase the odds of preterm birth, low birth weight and infant ...

A Digestive 'Treasure Chest' Shows Promise for Targeted Drug Treatment in the Gut

May 1, 2025 — A new approach to drug design can deliver medicine directly to the gut in mice at significantly lower doses than current inflammatory bowel disease treatments. The proof-of-concept study introduced a ...

Study Links Childhood Trauma to Increased Substance Use and Unexpected Effects on Heart Rate and Blood Pressure in Adolescents

Apr. 30, 2025 — Childhood trauma significantly increases the likelihood of engaging in harmful alcohol consumption, smoking and illicit drug use, by the age of ...

Mindfulness Therapy Reduces Opioid Craving and Addiction, Study Finds

Apr. 30, 2025 — Researchers found that Mindfulness-Oriented Recovery Enhancement (MORE) can help rewire the brain's response to natural healthy pleasure, leading to reduced opioid cravings. The findings suggest ...

Nearly One-Quarter of E-Scooter Injuries Involved Substance Impaired Riders

Apr. 29, 2025 — About 25% of 7350 patients hospitalized for scooter-related injuries between 2016 and 2021 were using substances such as alcohol, opioids, marijuana and cocaine when injured. The findings underscore ...

First Synthetic 'Mini Prion' Shows How Protein Misfolding Multiplies

Apr. 28, 2025 — Prions transmit their abnormally folded shape onto other proteins. Researchers designed a synthetic fragment of the tau protein that exhibits prion-like behavior. Misfolded tau proteins are the ...

Physical and Psychological Symptoms of Ketamine Abuse Revealed in Research

Apr. 28, 2025 — Ketamine addiction is linked to high levels of physical health problems and psychological consequences, with nearly half of those affected not seeking support or treatment, new research has ...

Cinnamon Could Affect Drug Metabolism in the Body

Apr. 24, 2025 — Cinnamon is one of the oldest and most commonly used spices in the world, but a new study indicates a compound in it could interfere with some prescription ...

More Americans Are Using Psilocybin -- Especially Those With Mental Health Conditions, Study Shows

Apr. 21, 2025 — Use of psilocybin, the hallucinogenic chemical found in what is known as 'magic mushrooms,' has increased significantly nationwide since 2019, according to a new ...

How Disturbed Signaling Pathways Could Promote Epileptic Seizures

Apr. 16, 2025 — Focal cortical dysplasia (FCD) type 2 is a congenital malformation of the cerebral cortex that is often associated with difficult-to-treat epilepsy. In the affected areas, nerve cells and their layer ...

LSD Analogue With Potential for Treating Schizophrenia Developed

Apr. 14, 2025 — Researchers have developed a new, neuroplasticity-promoting drug closely related to LSD that harnesses the psychedelic's therapeutic power with reduced hallucinogenic ...

Brain Study Increases Understanding of What Triggers Drug Use Relapse

Apr. 10, 2025 — Research on the biological basis of addiction has found that the critical epigenetic enzyme histone deacetylase 5 (HDAC5) limits the expression of the gene Scn4b, regulating neuronal activity and ...

Brain Pathway Links Inflammation to Loss of Motivation, Energy in Advanced Cancer

Apr. 10, 2025 — Researchers identified a direct connection between cancer-related inflammation and the loss of motivation characteristic of advanced cancer. In a mouse study, they describe a brain pathway that ...

'Eolving' Opioid Epidemic Across U.S.

Apr. 10, 2025 — The heart of the opioid epidemic that killed 665,341 people in the United States between 2005 and 2020 shifted geographically from the Northwest to the East, according to a new geographical ...

Simultaneous Alcohol, Cannabis Use May Fuel More Drinking

Apr. 10, 2025 — A recent study found that people may perceive fewer negative effects of alcohol if they are also using cannabis at the same ...

What Links Cannabis Use and Psychosis? Researchers Point to Brain's Dopamine System

Apr. 9, 2025 — A new study found that people with cannabis use disorder (CUD) had elevated dopamine levels in a brain region associated with ...

By Re-Creating Neural Pathway in Dish, Stanford Medicine Research May Speed Pain Treatment

Apr. 9, 2025 — Scientists have rebuilt, in laboratory glassware, the neural pathway that sends information from the body's periphery to the brain, promising to aid research on pain ...