Colitis News

June 3, 2025

Top Headlines

Preventing Chronic Inflammation from Turning Into Cancer

June 2, 2025 — Chronic inflammatory bowel disease is challenging to treat and carries a risk of complications, including the development of bowel cancer. Young people are particularly affected: when genetic predisposition and certain factors coincide, diseases ...

Mediterranean Diet Provides Symptom Relief for Patients With IBS in Pilot Study

May 30, 2025 — In a comparative pilot study, the Mediterranean diet and the low FODMAP diet both provided relief for patients with ...

IBD on the Rise: International Research Highlights Spread in Africa, Asia, and Latin America

May 28, 2025 — New research conducted by an international consortium shows that IBD and related conditions are now spreading through developing regions in Africa, Asia, and Latin ...

Oxygen Deprivation Promotes Colon Cancer Growth

May 21, 2025 — Researchers found that the Wnt5a protein, secreted by inflammatory fibroblasts within cancerous tumors, inhibits angiogenesis and consequently promotes hypoxia within tumors. Hypoxic conditions help sustain the inflammatory fibroblasts, which also ...

Latest Headlines

updated 10:43pm EDT

Fast Food, Fast Impact: How Fatty Meals Rapidly Weaken Our Gut Defenses

May 19, 2025 — A study has become the first in the world to unravel the immediate effects of a high-fat diet on our gut ...

Colonic Inflammation Explains Missing Link Between Obesity and Beta-Cell Proliferation

May 9, 2025 — How does obesity affect insulin production? Researchers are shining light on new stages of the ERK ...

A Digestive 'Treasure Chest' Shows Promise for Targeted Drug Treatment in the Gut

May 1, 2025 — A new approach to drug design can deliver medicine directly to the gut in mice at significantly lower doses than current inflammatory bowel disease ...

Lower Screening Age Calls for More Tailored Bowel Cancer Surveillance

Apr. 30, 2025 — Australia's recent move to lower the starting age for bowel (colorectal) cancer screening from 50 down to 45 years old will mean better outcomes -- but it will also increase the burden on an already ...

Cerebral Palsy Medications Given to Adults May Not Match Needs

Apr. 17, 2025 — Some medications are seen as a 'fix-all' solution, not addressing the root ...

Patient Navigators Improve Colonoscopy Rates After Abnormal Stool Tests, Study Shows

Mar. 31, 2025 — Timely follow-up colonoscopies can reduce the mortality rate from colorectal cancer, and patient navigators can play an important role in ...

'Switch' Allows Intestinal Cells to Regenerate After Injury

Mar. 25, 2025 — Researchers have solved a cellular mystery that may lead to better therapies for colorectal and other types of cancer. A professor of pediatrics-developmental biology and an assistant professor of ...

Cellular Mechanisms That May Lead to Onset of Inflammatory Bowel Disease

Mar. 21, 2025 — New study shows that dysfunction of protective immune cells in GI tract may contribute to onset of inflammation in Crohn's ...

Pregnancy Irreversibly Remodels the Mouse Intestine

Mar. 19, 2025 — Researchers have found that the small intestine grows in response to pregnancy in mice. This partially irreversible change may help mice support a pregnancy and prepare for a ...

Study Confirms Safety and Efficacy of Higher-Dose-Per-Day Radiation for Early-Stage Prostate Cancer

Mar. 18, 2025 — A large-scale study provides the strongest evidence yet that a shorter, standard-dose course radiation treatment is just as effective as conventional ...

Treating Chronic Inflammatory Diseases With JAK Inhibitors

Mar. 17, 2025 — Janus kinase inhibitors (JAKis) are an important treatment option for people with chronic inflammatory diseases such as rheumatoid arthritis, psoriasis, Crohn's disease or ulcerative colitis. ...

Focus on the Gut-Liver Axis: Semisynthetic Bile Acid Has Anti-Inflammatory Effects on the Gut

Mar. 13, 2025 — A research team has made further progress in the treatment of intestinal inflammation. A study shows that the semi-synthetic bile acid NorUDCA inhibits in the intestine the formation of ...

Gut Bacteria Heal the Colon

Mar. 10, 2025 — Scientists have uncovered how a gut bacterium, Clostridium scindens, aids in healing intestinal injuries by restoring bile acid balance. Their findings could pave the way for new treatments for ...

Possible Biomarker Identified for Crohn's Disease With Arthritis Type

Mar. 5, 2025 — People with Crohn's disease and related joint inflammation linked to immune system dysfunction have distinct gut bacteria or microbiota, with the bacterium Mediterraneibacter gnavus being a ...

School Absence Patterns Could ID Children With Chronic GI Disorders, Research Suggests

Mar. 4, 2025 — Children who frequently miss school because of abdominal complaints are far more likely to be suffering from chronic disorders such as irritable bowel syndrome than diseases that can be detected with ...

We Feed Gut Microbes Sugar, They Make a Compound We Need

Mar. 3, 2025 — Gut microbes that were thought to feed exclusively on dietary fiber also get fed sugar from our guts, from which they produce short-chain fatty acids that are crucial to many body functions. The ...

How a Low-Carb Diet Can Drive Colorectal Cancer Development

Mar. 3, 2025 — Researchers have shown how a low carbohydrate diet can worsen the DNA-damaging effects of some gut microbes to cause colorectal cancer. The study compared the effects of three different diets in ...

Synthetic Microbiome Therapy Suppresses Bacterial Infection Without Antibiotics

Mar. 3, 2025 — A synthetic microbiome therapy, tested in mice, holds promise as a new treatment for C. difficile, a notoriously difficult-to-treat bacterial infection, according to a team of researchers. The ...

Ginger Compound Has Potential to Treat Inflammatory Bowel Disease

Feb. 19, 2025 — Researchers have found a compound in ginger, called furanodienone (FDN), that selectively binds to and regulates a nuclear receptor involved in inflammatory bowel disease (IBD). While researchers ...

Biologists Transform Gut Bacteria Into Tiny Protein Pharmacies

Feb. 18, 2025 — Biologists converted gut bacteria into miniature protein factories that manufacture and release a sustained flow of targeted proteins inside the lower intestines. This technique solves one of the ...

Research Shows Blood Test May Provide Personalized Dietary Therapy for Patients With Irritable Bowel Syndrome

Feb. 13, 2025 — Study participants who went on an IgG-based elimination diet--based on a novel blood test--experienced less abdominal pain than those on a sham ...

Microbiome as a Potential Key to Better Treatment: Clinical Study on New Therapy for Crohn's Disease

Feb. 11, 2025 — A special liquid diet, known as exclusive enteral nutrition, is an essential therapy for Crohn's disease. Patients consume only this formula for six to eight weeks, completely avoiding solid ...

Beyond the Gut: A New Frontier in IBS Treatment by Targeting the Brain

Feb. 5, 2025 — Irritable bowel syndrome (IBS) is a common digestive disorder with unclear causes, affecting about 10% of the global population. Researchers have now discovered that opioid delta-receptor agonists ...

Study Establishes Link Between Early Side Effects from Prostate Cancer Radiation and Long-Term Side Effects

Jan. 31, 2025 — Men undergoing radiation therapy for prostate cancer who experience side effects early in treatment may face a higher risk of developing more serious long-term urinary and bowel health issues, ...

Could Fecal Microbiota Transplantation Help Patients Heal After Stem Cell Transplantation?

Jan. 28, 2025 — A new study shows that oral fecal microbiota transplantation (FMT) is a feasible and safe addition to preventing graft-versus-host disease in patients undergoing stem cell transplantation for blood ...

Blood Test Could Guide Use of Anti-Inflammatory Drug Celecoxib to Reduce Risk of Colon Cancer Recurrence

Jan. 28, 2025 — A data analysis from a randomized clinical trial for stage 3 colon cancer patients found that patients with evidence of residual cancer in their blood after surgery to remove the cancer, may benefit ...

PET Probe Images Inflammation With High Sensitivity and Selectivity

Jan. 22, 2025 — Researchers have developed a breakthrough method to detect inflammation in the body using positron emission tomography (PET) imaging. This innovative probe targets CD45, a marker abundantly expressed ...

Inflammation May Explain Stomach Problems in Psoriasis Sufferers

Jan. 20, 2025 — People with the skin condition psoriasis often have invisible inflammation in the small intestine with an increased propensity for 'leaky gut', according to new research. These changes in ...

Wearable Devices Can Detect and Predict Inflammatory Bowel Disease Flare-Ups

Jan. 16, 2025 — Data collected by wearable technology can identify disease flare-ups up to seven weeks in ...

Fatal Neurodegenerative Disease in Kids Also Affects the Bowel

Jan. 15, 2025 — Researchers have described the neurodegeneration that occurs in the nervous system of the bowel in Batten disease, a rare and fatal genetic condition. In their latest study, a team showed that gene ...