Colitis News

March 27, 2025

Top Headlines

'Switch' Allows Intestinal Cells to Regenerate After Injury

Mar. 25, 2025 — Researchers have solved a cellular mystery that may lead to better therapies for colorectal and other types of cancer. A professor of pediatrics-developmental biology and an assistant professor of molecular, cellular, and developmental biology have ...

Cellular Mechanisms That May Lead to Onset of Inflammatory Bowel Disease

Mar. 21, 2025 — New study shows that dysfunction of protective immune cells in GI tract may contribute to onset of inflammation in Crohn's ...

Pregnancy Irreversibly Remodels the Mouse Intestine

Mar. 19, 2025 — Researchers have found that the small intestine grows in response to pregnancy in mice. This partially irreversible change may help mice support a pregnancy and prepare for a ...

Study Confirms Safety and Efficacy of Higher-Dose-Per-Day Radiation for Early-Stage Prostate Cancer

Mar. 18, 2025 — A large-scale study provides the strongest evidence yet that a shorter, standard-dose course radiation treatment is just as effective as conventional radiotherapy for prostate cancer, without ...

Latest Headlines

updated 10:16pm EDT

Treating Chronic Inflammatory Diseases With JAK Inhibitors

Mar. 17, 2025 — Janus kinase inhibitors (JAKis) are an important treatment option for people with chronic inflammatory diseases such as rheumatoid arthritis, psoriasis, Crohn's disease or ulcerative colitis. Since ...

Gut Bacteria Heal the Colon

Mar. 10, 2025 — Scientists have uncovered how a gut bacterium, Clostridium scindens, aids in healing intestinal injuries by restoring bile acid balance. Their findings could pave the way for new treatments for ...

Focus on the Gut-Liver Axis: Semisynthetic Bile Acid Has Anti-Inflammatory Effects on the Gut

Mar. 13, 2025 — A research team has made further progress in the treatment of intestinal inflammation. A study shows that the semi-synthetic bile acid NorUDCA ...

Possible Biomarker Identified for Crohn's Disease With Arthritis Type

Mar. 5, 2025 — People with Crohn's disease and related joint inflammation linked to immune system dysfunction have distinct gut bacteria or microbiota, with the bacterium Mediterraneibacter gnavus being a potential ...

School Absence Patterns Could ID Children With Chronic GI Disorders, Research Suggests

Mar. 4, 2025 — Children who frequently miss school because of abdominal complaints are far more likely to be suffering from chronic disorders such as irritable ...

Synthetic Microbiome Therapy Suppresses Bacterial Infection Without Antibiotics

Mar. 3, 2025 — A synthetic microbiome therapy, tested in mice, holds promise as a new treatment for C. difficile, a notoriously difficult-to-treat bacterial ...

We Feed Gut Microbes Sugar, They Make a Compound We Need

Mar. 3, 2025 — Gut microbes that were thought to feed exclusively on dietary fiber also get fed sugar from our guts, from which they produce short-chain fatty acids that are crucial to many body functions. The ...

How a Low-Carb Diet Can Drive Colorectal Cancer Development

Mar. 3, 2025 — Researchers have shown how a low carbohydrate diet can worsen the DNA-damaging effects of some gut microbes to cause colorectal cancer. The study compared the effects of three different diets in ...

Biologists Transform Gut Bacteria Into Tiny Protein Pharmacies

Feb. 18, 2025 — Biologists converted gut bacteria into miniature protein factories that manufacture and release a sustained flow of targeted proteins inside the lower intestines. This technique solves one of the ...

Ginger Compound Has Potential to Treat Inflammatory Bowel Disease

Feb. 19, 2025 — Researchers have found a compound in ginger, called furanodienone (FDN), that selectively binds to and regulates a nuclear receptor involved in inflammatory bowel disease (IBD). While researchers ...

Research Shows Blood Test May Provide Personalized Dietary Therapy for Patients With Irritable Bowel Syndrome

Feb. 13, 2025 — Study participants who went on an IgG-based elimination diet--based on a novel blood test--experienced less abdominal pain than those on a sham ...

Microbiome as a Potential Key to Better Treatment: Clinical Study on New Therapy for Crohn's Disease

Feb. 11, 2025 — A special liquid diet, known as exclusive enteral nutrition, is an essential therapy for Crohn's disease. Patients consume only this formula for six to eight weeks, completely avoiding solid ...

Beyond the Gut: A New Frontier in IBS Treatment by Targeting the Brain

Feb. 5, 2025 — Irritable bowel syndrome (IBS) is a common digestive disorder with unclear causes, affecting about 10% of the global population. Researchers have now discovered that opioid delta-receptor agonists ...

Study Establishes Link Between Early Side Effects from Prostate Cancer Radiation and Long-Term Side Effects

Jan. 31, 2025 — Men undergoing radiation therapy for prostate cancer who experience side effects early in treatment may face a higher risk of developing more serious long-term urinary and bowel health issues, ...

Could Fecal Microbiota Transplantation Help Patients Heal After Stem Cell Transplantation?

Jan. 28, 2025 — A new study shows that oral fecal microbiota transplantation (FMT) is a feasible and safe addition to preventing graft-versus-host disease in patients undergoing stem cell transplantation for blood ...

Blood Test Could Guide Use of Anti-Inflammatory Drug Celecoxib to Reduce Risk of Colon Cancer Recurrence

Jan. 28, 2025 — A data analysis from a randomized clinical trial for stage 3 colon cancer patients found that patients with evidence of residual cancer in their blood after surgery to remove the cancer, may benefit ...

PET Probe Images Inflammation With High Sensitivity and Selectivity

Jan. 22, 2025 — Researchers have developed a breakthrough method to detect inflammation in the body using positron emission tomography (PET) imaging. This innovative probe targets CD45, a marker abundantly expressed ...

Inflammation May Explain Stomach Problems in Psoriasis Sufferers

Jan. 20, 2025 — People with the skin condition psoriasis often have invisible inflammation in the small intestine with an increased propensity for 'leaky gut', according to new research. These changes in ...

Wearable Devices Can Detect and Predict Inflammatory Bowel Disease Flare-Ups

Jan. 16, 2025 — Data collected by wearable technology can identify disease flare-ups up to seven weeks in ...

Fatal Neurodegenerative Disease in Kids Also Affects the Bowel

Jan. 15, 2025 — Researchers have described the neurodegeneration that occurs in the nervous system of the bowel in Batten disease, a rare and fatal genetic condition. In their latest study, a team showed that gene ...

Hidden Mechanism of Swallowing Revealed by Caenorhabditis Elegans

Dec. 20, 2024 — New researchers uncover the role of Piezo channels that sense pressure in the digestive tract and regulate swallowing behavior. The research opens new opportunities for developing treatments for ...

Potential Culprit Identified in Lingering Crohn's Disease Symptoms

Dec. 19, 2024 — A study may explain why some patients with Crohn's disease continue to experience symptoms, even in the absence of ...

How a New Gut Microbe Drives the Gut-Lung Axis

Dec. 19, 2024 — A team has discovered a new communication pathway between the gut and lung. Their findings highlight how a little-known member of the gut microbiome reshapes the lung immune environment to have both ...

Is Fake Meat Good to Eat? Processed Plant-Based Meat Alternatives Linked to Depression Risk in Vegetarians

Dec. 17, 2024 — Researchers found that vegetarians who consumed PBMAs had a 42% increased risk of depression compared to vegetarians who refrained from ...

Researchers Find Previously Unknown Links Between Microbial Bile Acids and the Risk of Colon Cancer

Dec. 16, 2024 — Microbes living in our guts help us digest food by reshaping the bile acids that our livers produce for breaking down fats. It turns out that two of these microbially-modified bile acids may affect ...

Ugh, My Stomach: Identifying Amino Acids That Prevent Sporulation in Food Poisoning

Dec. 12, 2024 — A team analyzed the amino acids that affect the formation of spores in a bacterium that causes food poisoning, Clostridium perfringens, and identified serine as an amino acid that inhibits spore ...

The Maternal Microbiome During Pregnancy Impacts Offspring's Stem Cells in Mice

Dec. 11, 2024 — Gut microbiome composition during pregnancy has long-term effects on offspring stem cell growth and development, researchers report. Treating pregnant mice with a common gut microbe resulted in ...

MRI Could Be Key to Understanding the Impact a Gluten Free Diet Has on People With Celiac Disease

Dec. 6, 2024 — Experts have used magnetic resonance imaging (MRI) to better understand the impact a gluten free diet has on people with celiac disease, which could be the first step towards finding new ways of ...

All People Are Unique -- Also in the Gut

Dec. 2, 2024 — A new study increases our knowledge about the gut and the life of gut bacteria. The study shows, among other things, that changes in the gut environment have an impact on the composition and activity ...

Critical Relationship Between Stem Cells and Mechanical Signals Unveiled

Dec. 2, 2024 — Researchers uncover how two mechano-sensing ion channels are essential to maintain healthy stem ...