Alzheimer's Research News

December 8, 2025

Top Headlines

A Routine Shingles Shot May Offer Powerful Defense Against Dementia

Dec. 3, 2025 A unique vaccine rollout in Wales gave researchers an accidental natural experiment that revealed a striking reduction in dementia among seniors who received the shingles vaccine. The protective effect held steady across multiple analyses and was ...

Your Body May Already Have a Molecule That Helps Fight Alzheimer’s

Nov. 27, 2025 Spermine, a small but powerful molecule in the body, helps neutralize harmful protein accumulations linked to Alzheimer’s and Parkinson’s. It encourages these misfolded proteins to gather into manageable clumps that cells can more efficiently ...

A Common Nutrient Deficiency May Be Silently Harming Young Brains

Nov. 27, 2025 Scientists studying young adults with obesity discovered early indicators of brain stress that resemble patterns seen in cognitive impairment. The group showed higher inflammation, signs of liver strain and elevated neurofilament light chain, a ...

Boosting One Protein Helps the Brain Protect Itself from Alzheimer’s

Nov. 23, 2025 Researchers discovered that raising the protein Sox9 can help the brain’s astrocytes clear out toxic plaque buildup linked to Alzheimer’s. In mouse models that already showed memory problems, activating these cells improved cognitive ...

Simple Amino Acid Supplement Greatly Reduces Alzheimer’s Damage

Nov. 21, 2025 Researchers discovered that the common amino acid arginine can block harmful Aβ aggregation and reduce its toxic effects in Alzheimer’s disease models. In flies and mice, oral arginine lowered plaque levels, reduced inflammation, and improved ...

Clearing Brain Plaques Isn’t Enough to Heal Alzheimer’s

Nov. 11, 2025 Japanese researchers found that lecanemab, an amyloid-clearing drug for Alzheimer’s, does not improve the brain’s waste clearance system in the short term. This implies that nerve damage and impaired clearance occur early and are difficult to ...

Scientists Find Hidden Brain Source That Fuels Dementia

Nov. 6, 2025 Weill Cornell researchers uncovered how free radicals from astrocyte mitochondria can fuel dementia. Using new compounds that target these radicals at their source, they slowed brain inflammation and neuronal damage in mice. The findings reveal a ...

Scientists May Have Found How to Reverse Memory Loss in Aging Brains

Nov. 5, 2025 Virginia Tech researchers have shown that memory loss in aging may be reversible. Using CRISPR tools, they corrected molecular disruptions in the hippocampus and amygdala, restoring memory in older rats. Another experiment revived a silenced memory ...

Alzheimer’s Might Be Powered by a Broken Sleep-wake Cycle

Nov. 3, 2025 Disrupted sleep patterns in Alzheimer’s disease may be more than a symptom—they could be a driving force. Researchers at Washington University found that the brain’s circadian rhythms are thrown off in key cell types, changing when hundreds of ...

Scientists Reverse Alzheimer’s in Mice with Groundbreaking Nanotech

Oct. 30, 2025 Researchers used supramolecular nanoparticles to repair the brain’s vascular system and reverse Alzheimer’s in mice. Instead of carrying drugs, the nanoparticles themselves triggered natural clearance of amyloid-β proteins. This restored ...

A “Toxic Duo” May Be the Hidden Trigger Behind Alzheimer’s Disease

Oct. 22, 2025 Scientists have uncovered a toxic alliance between Aβ and fibrinogen that may explain how Alzheimer’s disease begins. The two proteins together create stubborn clots that damage blood vessels and spark inflammation in the brain. These effects ...

This New Iron Supplement Heals Anemia Without Hurting Your Gut

Oct. 20, 2025 Researchers have created a new iron supplement that merges iron, probiotics, and prebiotics. This “three-in-one” formula restores iron levels while maintaining gut health and preventing inflammation. In mice studies, it normalized hemoglobin and ...

Latest Headlines

updated 11:48am EST

Simple Molecule Shows Remarkable Alzheimer’s Reversal in Rats

Nov. 19, 2025 Scientists have developed a new molecule that breaks down beta-amyloid plaques by binding to excess copper in the brain. The treatment restored memory and reduced inflammation in rats, while also ...

Walking May Be the Brain’s Best Defense Against Alzheimer’s

Nov. 4, 2025 Walking a few thousand steps daily may help hold off Alzheimer’s for years, a Mass General Brigham study found. Even moderate physical activity slowed both cognitive decline and the buildup of ...

How Strong Is Your Weed, Really? Scientists Say Labels Often Mislead

Oct. 23, 2025 Colorado researchers discovered that nearly half of tested cannabis flower products exaggerated their THC levels, while concentrates were mostly accurate. The team’s statewide audit revealed ...

These 80-Year-Olds Have the Memory of 50-Year-Olds. Scientists Finally Know Why

Oct. 19, 2025 SuperAgers defy normal aging by keeping sharp memories and healthy brains well into their 80s. Northwestern scientists discovered that these ...

Supercharged Vitamin K Could Help the Brain Heal Itself

Oct. 14, 2025 Researchers have synthesized enhanced vitamin K analogues that outperform natural vitamin K in promoting neuron growth. The new compounds, which combine vitamin K with retinoic acid, activate the ...

A Toxic Alzheimer’s Protein Could Be the Key to Fighting Cancer

Oct. 10, 2025 A surprising link between Alzheimer’s and cancer reveals that amyloid beta, a harmful protein in the brain, actually empowers the immune system. It strengthens T-cells’ energy production, helping ...

Nearly Half of Drivers Killed in Crashes Had THC in Their Blood

Oct. 5, 2025 Over 40% of fatal crash victims had THC levels far above legal limits, showing cannabis use before driving remains widespread. The rate didn’t drop after legalization, suggesting policy changes ...

Think Light Drinking Protects Your Brain? Think Again

Oct. 4, 2025 A massive new study combining observational and genetic data overturns the long-held belief that light drinking protects the brain. Researchers found that dementia risk rises in direct proportion to ...

Fat May Secretly Fuel Alzheimer’s, New Research Finds

Oct. 3, 2025 New research from Houston Methodist reveals how obesity may directly drive Alzheimer’s disease. Scientists discovered that tiny messengers released by fat tissue, called extracellular vesicles, can ...

Hidden Alzheimer’s Warning Signs Found in Parkinson’s Patients Without Dementia

Sep. 28, 2025 Researchers in Japan discovered that Parkinson’s patients diagnosed in their 80s are far more likely to show signs of amyloid buildup, a hallmark ...

Brain Fat, Not Just Plaques, May Be the Hidden Driver of Alzheimer’s

Sep. 24, 2025 For decades, scientists believed Alzheimer’s was driven mainly by sticky protein plaques and tangles in the brain. Now Purdue researchers have revealed a hidden culprit: fat. They found that brain ...

Sleepless Nights May Raise Dementia Risk by 40%, Mayo Clinic Reveals

Sep. 14, 2025 Chronic insomnia may do more than leave you groggy, it could speed up brain aging. A large Mayo Clinic study found that people with long-term sleep troubles were 40% more likely to develop dementia ...

Simple Blood Test Could Spot Alzheimer’s Years Before Symptoms

Sep. 9, 2025 Scientists discovered that certain blood proteins linked to brain injury and inflammation strongly correlate with early signs of memory and cognitive decline, especially in Hispanic and Latino ...

A 3-Minute Brainwave Test Could Spot Alzheimer’s Years Before Symptoms

Sep. 4, 2025 Scientists at the University of Bath have developed a simple three-minute brainwave test called Fastball EEG that can detect memory problems years before Alzheimer’s is typically diagnosed. Unlike ...

Common Heart Drug Taken by Millions Found Useless, Possibly Risky

Aug. 31, 2025 Beta blockers, used for decades after heart attacks, provide no benefit for patients with preserved heart function, according to the REBOOT trial. The massive study also found women faced higher ...

Cannabis for Coping? Why It May Trigger Paranoia

Aug. 28, 2025 Using cannabis to self-medicate comes with hidden dangers—new research shows these users face higher paranoia and consume more THC. Childhood trauma further amplifies the risks, especially ...

Stronger Weed, Higher Risk? Potent THC Linked to Psychosis and Addiction

Sep. 2, 2025 A sweeping review of nearly 100 studies has raised concerns about the mental health impacts of high-potency cannabis products. Researchers found strong links to psychosis, schizophrenia, and cannabis ...

Tiny Protein Dismantles the Toxic Clumps Behind Alzheimer’s

Aug. 23, 2025 St. Jude researchers revealed that midkine blocks amyloid beta from forming harmful clumps linked to Alzheimer’s. Without it, the damaging assemblies accelerate, but with it, growth halts. The ...

How Cats With Dementia Could Help Crack the Alzheimer’s Puzzle

Aug. 14, 2025 Cats can naturally develop dementia with brain changes strikingly similar to Alzheimer’s disease in humans, including toxic amyloid-beta buildup and loss of synapses. A new study shows these ...

The Hidden Mental Health Danger in Today’s High-THC Cannabis

Aug. 12, 2025 THC levels in cannabis have soared in recent years, raising the risk of psychosis—especially in young, frequent users. Studies reveal a strong connection between cannabis-induced psychosis and ...

Scientists Reversed Memory Loss by Powering the Brain’s Tiny Engines

Aug. 12, 2025 Scientists have discovered a direct cause-and-effect link between faulty mitochondria and the memory loss seen in neurodegenerative diseases. By creating a novel tool to boost mitochondrial activity ...

Lithium Deficiency May Be the Hidden Spark Behind Alzheimer’s

Aug. 29, 2025 Harvard scientists have uncovered that lithium, a naturally occurring element in the brain, may be the missing piece in understanding Alzheimer’s. Their decade-long research shows that lithium ...

This Sugar Molecule Could Stop Type 1 Diabetes, by Fooling the Immune System

Aug. 2, 2025 In a fascinating twist, Mayo Clinic researchers discovered that a sugar molecule cancer cells use to hide from the immune system might also protect insulin-producing beta cells in type 1 diabetes. By ...

Think It’s Just Aging? Why Dementia Is Missed for 3.5 Years on Average

July 27, 2025 Many people with dementia endure long delays often over 3 years before receiving a diagnosis, with even longer waits for younger patients. A global review of over 30,000 cases reveals that age, ...

Scientists Discover the Receptor That Helps Your Brain Clean Itself—and Fight Alzheimer’s

July 27, 2025 Scientists at UCSF have uncovered how certain immune cells in the brain, called microglia, can effectively digest toxic amyloid beta plaques that cause Alzheimer’s. They identified a key receptor, ...

Is the Air You Breathe Silently Fueling Dementia? A 29-Million-Person Study Says Yes

July 27, 2025 Air pollution isn't just bad for your lungs—it may be eroding your brain. In a sweeping review covering nearly 30 million people, researchers found that common pollutants like PM2.5, nitrogen ...

Synthetic Storm: What’s Really in Your Teen’s Vape — and Why Scientists Are Alarmed

July 1, 2025 Teen vaping is changing fast — and not in a good way. A large national study found that more adolescents are vaping THC, CBD, and especially synthetic cannabinoids, which are often unregulated and ...

Iron Overload: The Hidden Culprit Behind Early Alzheimer’s in Down Syndrome

June 20, 2025 USC researchers have uncovered a hidden driver behind the early and severe onset of Alzheimer's in people with Down syndrome: iron overload in the brain. Their study revealed that individuals ...

Microscopic Heist: How Lung Bacteria Forge Weapons to Steal Iron and Survive

June 19, 2025 Researchers investigating the enigmatic and antibiotic-resistant Pandoraea bacteria have uncovered a surprising twist: these pathogens don't just pose risks they also produce powerful natural ...

Hidden in Your Dna: The Mutation Combo That Raises Clot Risk by 180%

June 8, 2025 Genetic research in Sweden has unveiled three new gene variants that dramatically increase the risk of venous blood clots, sometimes by up to 180%. These discoveries build on existing knowledge of ...