Pharmaceuticals News

November 22, 2025

Top Headlines

New Evidence Shows Tirzepatide and Semaglutide Strongly Protect the Heart

Nov. 21, 2025 A massive real-world study comparing tirzepatide and semaglutide reveals both drugs deliver strong, early cardiovascular protection—reducing heart attack, stroke, and death in adults with type 2 diabetes. While companies have claimed large ...

Blocking a Single Protein Forces Cancer Cells to Self-destruct

Nov. 20, 2025 Researchers uncovered a powerful weakness in lung cancer by shutting down a protein that helps tumors survive stress. When this protein, FSP1, was blocked, lung tumors in mice shrank dramatically, with many cancer cells essentially triggering their ...

Scientists Reawaken Exhausted T Cells to Supercharge Cancer Immunity

Nov. 20, 2025 Researchers discovered a way to keep T cells from wearing out during the fight against cancer, and the approach could make immune-based treatments far more powerful. They found that tumors use a particular molecular signal to weaken T cells, and ...

Inflammation Turns Bone Marrow Into a Breeding Ground for Disease

Nov. 19, 2025 Researchers discovered that chronic inflammation fundamentally remodels the bone marrow, allowing mutated stem cell clones to quietly gain dominance with age. Reprogrammed stromal cells and interferon-responsive T cells create a self-sustaining ...

Tiny Implant Wipes Out Bladder Cancer in 82% of Patients

Nov. 11, 2025 TAR-200, a small drug-releasing implant, wiped out tumors in most patients with high-risk bladder cancer. Its slow, consistent release of chemotherapy proved far more effective than traditional short-term treatments. The therapy may replace bladder ...

New Bacterial Therapy Destroys Cancer Without the Immune System

Nov. 9, 2025 A Japanese-led research team has developed AUN, a groundbreaking immune-independent bacterial cancer therapy that uses two harmonized bacteria to destroy tumors even in patients with weakened immune systems. By leveraging the natural synergy between ...

A Simple DNA Test Could Reveal the Right Antidepressant for You

Nov. 9, 2025 Millions struggle with depression and anxiety, often enduring long waits for effective treatment. Scientists in Sweden, Denmark, and Germany are developing a genetic test to predict which medications will actually work. Using polygenic risk scores, ...

The Hidden “Big Bang” That Decides How Bowel Cancer Grows

Nov. 7, 2025 Scientists have pinpointed a “Big Bang” moment in bowel cancer—when cells first evade the immune system. This early immune escape locks in how the cancer will behave as it grows. The discovery could help predict which patients respond to ...

Common Acne Drug May Protect Against Schizophrenia

Nov. 6, 2025 Scientists have discovered a surprising benefit of the acne drug doxycycline: it may lower the risk of schizophrenia. Teens prescribed the antibiotic were about one-third less likely to develop the condition as adults. The effect could stem from the ...

Scientists Shocked to Find E. Coli Spreads as Fast as the Swine Flu

Nov. 4, 2025 Researchers have, for the first time, estimated how quickly E. coli bacteria can spread between people — and one strain moves as fast as swine flu. Using genomic data from the UK and Norway, scientists modeled bacterial transmission rates and ...

Think Melatonin Is Safe? New Research Reveals a Hidden Heart Risk

Nov. 4, 2025 Long-term melatonin use for sleep problems may come with unexpected heart dangers. Researchers found that chronic users were almost twice as likely to die and 3.5 times more likely to be hospitalized for heart failure. Though melatonin is widely ...

Ancient Viruses Hidden Inside Bacteria Could Help Defeat Modern Infections

Nov. 3, 2025 Penn State scientists uncovered an ancient bacterial defense where dormant viral DNA helps bacteria fight new viral threats. The enzyme PinQ flips bacterial genes to create protective proteins that block infection. Understanding this mechanism could ...

Latest Headlines

updated 5:12am EST

Wegovy in a Pill? Massive Weight Loss Results Revealed

Nov. 6, 2025 Novo Nordisk’s oral semaglutide 25 mg achieved up to 16.6% weight loss in a landmark study, rivaling injectable Wegovy. The pill also improved cardiovascular risk factors and physical activity ...

A Gene from 100-Year-Olds Could Help Kids Who Age Too Fast

Nov. 3, 2025 Scientists have discovered that a “longevity gene” found in people who live beyond 100 can reverse heart aging in models of Progeria, a devastating disease that causes children to age rapidly. By ...

Ozempic and Wegovy Protect the Heart, Even Without Weight Loss

Oct. 31, 2025 Semaglutide appears to safeguard the heart even when patients lose little weight. In a massive international trial, heart attack and stroke risk dropped by 20% regardless of BMI. The benefit seems ...

Scientists Find Hidden Antibiotic 100x Stronger Against Deadly Superbugs

Oct. 29, 2025 A team of scientists discovered a hidden antibiotic 100 times stronger than existing drugs against deadly superbugs like MRSA. The molecule had been overlooked for decades in a familiar bacterium. It ...

Scientists Discover COVID mRNA Vaccines Boost Cancer Survival

Oct. 28, 2025 Researchers found that COVID-19 mRNA vaccines significantly increased survival in lung and skin cancer patients undergoing immunotherapy. The vaccine appears to prime the immune system in a powerful, ...

How Strong Is Your Weed, Really? Scientists Say Labels Often Mislead

Oct. 23, 2025 Colorado researchers discovered that nearly half of tested cannabis flower products exaggerated their THC levels, while concentrates were mostly accurate. The team’s statewide audit revealed ...

This Powerful Drug Combo Cuts Prostate Cancer Deaths by 40%

Oct. 19, 2025 A new drug combo of enzalutamide and hormone therapy has been shown to extend survival for men with recurring prostate cancer, reducing death risk by over 40%. The study followed more than 1,000 ...

Cancer Patients Who Got a COVID Vaccine Lived Much Longer

Oct. 19, 2025 A groundbreaking study reveals that cancer patients who received a COVID-19 mRNA vaccine within 100 days of starting immunotherapy lived dramatically longer than those who didn’t. Researchers from ...

Surgery Beats Ozempic for Long-Term Health, Cleveland Clinic Finds

Oct. 18, 2025 Weight-loss surgery dramatically outperformed GLP-1 medications in improving longevity and reducing heart, kidney, and eye complications for people with obesity and diabetes. Over 10 years, patients ...

This Common Liver Supplement Could Boost Cancer Treatment Success

Oct. 17, 2025 Salk Institute scientists discovered that bile acids in the liver can weaken immune cell function, making immunotherapy less effective against liver cancer. They pinpointed specific bile acids that ...

Scientists Grow Mini Human Livers That Predict Toxic Drug Reactions

Oct. 15, 2025 A new human liver organoid microarray developed by Cincinnati Children’s and Roche recreates immune-driven liver injury in the lab. Built from patient-derived stem cells and immune cells, it ...

Exercise Might Be the Key to a Younger, Sharper Immune System

Oct. 14, 2025 Endurance exercise may train the immune system as much as the muscles. Older adults with decades of running or cycling had immune cells that functioned better and aged more slowly. Their inflammation ...

Two Common Drugs Could Reverse Fatty Liver Disease

Oct. 12, 2025 Researchers at the University of Barcelona found that combining pemafibrate and telmisartan significantly reduces liver fat and cardiovascular risks in MASLD models. The drug duo works better ...

Brain Cancer That Eats the Skull Stuns Scientists

Oct. 5, 2025 A new study shows glioblastoma isn’t confined to the brain—it erodes the skull and hijacks the immune system within skull marrow. The cancer opens channels that let inflammatory cells enter the ...

Stunning Images Reveal How Antibiotics Shatter Bacterial Defenses

Sep. 29, 2025 Researchers have revealed how polymyxins, crucial last-resort antibiotics, break down bacterial armor by forcing cells to overproduce and shed it. Astonishingly, the drugs only kill bacteria when ...

Oct. 13, 2025 Finasteride, a common hair-loss drug, has long been tied to depression and suicide, but regulators ignored the warnings. Prof. Mayer Brezis’s review exposes global data showing psychiatric harm and ...

New Inhaler Halves Childhood Asthma Attacks

Sep. 28, 2025 A groundbreaking international study has shown that a 2-in-1 budesonide-formoterol inhaler is far more effective than the standard salbutamol inhaler in children with mild asthma, cutting attacks by ...

Scientists Uncover How to Block Pain Without Side Effects

Sep. 26, 2025 Scientists have discovered a way to block pain while still allowing the body’s natural healing to take place. Current painkillers like ibuprofen and aspirin often come with harmful side effects ...

The Hidden Iron Switch That Makes Cancer Cells Self-Destruct

Sep. 29, 2025 Scientists discovered that inhibiting the enzyme STK17B forces multiple myeloma cells into iron-driven death and makes therapies more effective. Early mouse studies show strong potential for a new ...

Cocoa Supplements Show Surprising Anti-Aging Potential

Sep. 27, 2025 Daily cocoa extract supplements reduced key inflammation markers in older adults, pointing to a role in protecting the heart. The findings reinforce the value of flavanol-rich, plant-based foods for ...

Scientists Reveal Pill That Helps Shed 20% of Body Weight

Sep. 24, 2025 A massive international study has shown that the experimental oral obesity drug orforglipron can help patients shed over 10% of their body weight, with nearly one in five losing 20% or more. Unlike ...

Semaglutide May Silence the Food Noise in Your Head

Sep. 16, 2025 People taking semaglutide report far fewer obsessive thoughts about food, with cravings dropping sharply and mental health improving. This new research hints the drug may offer freedom from the ...

A Hormone That Silences the Immune System May Unlock New Cancer Treatments

Sep. 22, 2025 Scientists have discovered that cancer uses a hidden hormone to switch off the body’s natural defenses, allowing tumors to grow unchecked. By uncovering this secret signal, they found a way to ...

A Single Protein Could Stop Sudden Death After Heart Attacks

Oct. 13, 2025 A team at Massachusetts General Hospital uncovered that an immune defense protein, Resistin-like molecule gamma, attacks heart cells after a heart attack—literally punching holes in them. This ...

Blood Test Spots Hidden Mesothelioma That Scans Can’t See

Sep. 11, 2025 New research suggests that immunotherapy given before and after surgery could help patients with diffuse pleural mesothelioma, one of the most challenging cancers to treat. A phase II clinical trial ...

New Pill Could Finally Control Stubborn High Blood Pressure

Oct. 8, 2025 A new pill called baxdrostat may offer hope for people whose blood pressure stays high even after taking standard medications. In a recent study, the drug lowered blood pressure and also seemed to ...

A Common Supplement Could Supercharge Cancer Treatments

Oct. 1, 2025 Zeaxanthin, best known for eye health, has been found to boost the tumor-killing power of T cells. Researchers showed it strengthens T-cell receptors, enhances immune signaling, and improves the ...

Why So Many Young Kids With ADHD Are Getting the Wrong Treatment

Sep. 16, 2025 Preschoolers with ADHD are often given medication right after diagnosis, against medical guidelines that recommend starting with behavioral therapy. Limited access to therapy and physician pressures ...

Alcohol’s Hidden Shortcut Lets Gut Bacteria Wreck the Liver

Sep. 19, 2025 Alcohol-associated liver disease is becoming a massive health and economic burden, but researchers at UC San Diego may have uncovered a new way forward. They discovered that chronic alcohol use ...

Hidden Gut Molecule Found to Wreck Kidneys

Sep. 12, 2025 Scientists discovered that a gut bacteria molecule called corisin can travel to the kidneys, triggering inflammation and scarring that lead to diabetic kidney fibrosis. By attaching to albumin in the ...