Stem Cells News

February 20, 2025

Top Headlines

Disruption of a Single Amino Acid in a Cellular Protein Makes Breast Cancer Cells Behave Like Stem Cells

Feb. 11, 2025 — Changes to the intermediate filament (IF) protein, vimentin, were found to promote tumor growth by increasing cancer stemness in an oestrogen independent manner. Targeting vimentin and/or the long ...

Uncovering How Developmental Genes Are Held in a Poised State

Feb. 6, 2025 — New research has investigated the mechanism by which bivalency functions to poise genes for expression during cell differentiation, providing insight into a long-standing paradigm in the regulation of developmental gene expression, revealing a key ...

Breakthrough in Childhood Brain Cancer Research Could Heal Treatment-Resistant Tumors, Keep Them in Remission

Feb. 4, 2025 — Research has shown that a potential new targeted therapy for childhood brain cancer is effective in infiltrating and killing tumor cells in preclinical models tested in mice. The novel drug CT-179 ...

How Healthy Stem Cells Turn Into Oral Cancer

Feb. 4, 2025 — Researchers have identified the molecular and cellular mechanisms that transform healthy stem cells into oral cancer at the earliest stages of the ...

Latest Headlines

updated 1:53pm EST

Research Discovery Halts Childhood Brain Tumor Before It Forms

Feb. 4, 2025 — A research team has identified a critical event driving tumor growth in a type of medulloblastoma -- and a way to block ...

New Research Unlocks Key to Long-Lasting Immune Response in Cancer and Chronic Diseases

Jan. 31, 2025 — Prolonged illnesses like cancer and chronic infections often leave the immune system in a state of exhaustion, where its frontline defenders -- T ...

First Mouse With Two Male Parents to Reach Adulthood

Jan. 28, 2025 — A team of stem cell scientists have successfully used embryonic stem cell engineering to create a bi-paternal mouse -- a mouse with two male parents -- that lived until adulthood. Their results ...

DNA Damage Can Last Unrepaired for Years, Changing Our View of Mutations

Jan. 15, 2025 — While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means that ...

Building a Backbone: Scientists Recreate the Body's 'GPS System' in the Lab

Dec. 18, 2024 — Scientists have generated human stem cell models which contain notochord -- a tissue in the developing embryo that acts like a navigation system, directing cells where to build the spine and nervous ...

Brain Cells Remain Healthy After a Month on the International Space Station, but Mature Faster Than Brain Cells on Earth

Dec. 17, 2024 — Microgravity is known to alter the muscles, bones, the immune system and cogni tion, but little is known about its specific impact on the brain. To ...

Neural Stem Cell Transplantation Shows Promise for Treating Chronic Spinal Cord Injury

Dec. 17, 2024 — Using neural stem cells could help treat spinal injuries once thought to be untreatable -- a new phase 1 trial has determined this approach is ...

New Drug Shows Promise Against Duchenne Muscular Dystrophy

Dec. 16, 2024 — A novel drug holds promise for treating Duchenne muscular dystrophy (DMD), a rare genetic disorder that causes severe muscle degeneration. Researchers have discovered that an experimental compound ...

Intermittent Fasting Inhibits Hair Regeneration in Mice

Dec. 13, 2024 — Intermittent fasting has proven benefits for metabolic health, but a new study shows that it could slow hair growth -- at least in mice. Researchers report that mice subjected to intermittent fasting ...

Study Breaks the Silence on How Fish and Lizards Regenerate Hearing

Dec. 9, 2024 — A new study has identified key gene regulators that enable some deafened animals -- including fish and lizards -- to naturally regenerate their hearing. The findings could guide future efforts to ...

Immune Complex Shaves Stem Cells to Protect Against Cancer

Jan. 17, 2025 — A group of immune proteins called the inflammasome can help prevent blood stem cells from becoming malignant by removing certain receptors from their surfaces and blocking cancer gene activity, ...

The Maternal Microbiome During Pregnancy Impacts Offspring's Stem Cells in Mice

Dec. 11, 2024 — Gut microbiome composition during pregnancy has long-term effects on offspring stem cell growth and development, researchers report. Treating pregnant mice with a common gut microbe resulted in ...

Nr1h2: A Key Transcription Factor Unlocks New Potential in Stem Cell-Based Embryo Models

Dec. 6, 2024 — Researchers have identified Nr1h2, a critical transcription factor essential for early embryo development. Their findings enhance our understanding of gene regulation during blastoid formation and ...

New Drug Tested to Reduce Side Effect of 'Half-Matched' Stem Cell Transplants

Dec. 5, 2024 — Stem cell transplantation is used to treat several types of blood cancers, but carries the risk of a life-threatening side effect called graft-versus-host disease. Results from a clinical trial ...

Changes in Blood Cell Production Over the Lifetime Could Impact Leukemia Outcomes

Dec. 5, 2024 — The first comprehensive map of the dramatic changes that take place in the blood system over the course of the human lifetime could have implications for the treatment of acute myeloid leukemia and ...

How Breast Cancer Cells Survive in Bone Marrow After Remission

Dec. 4, 2024 — A new study has shed light on a previously poorly understood aspect of breast cancer recurrence: how cancer cells survive in bone marrow despite targeted ...

Critical Relationship Between Stem Cells and Mechanical Signals Unveiled

Dec. 2, 2024 — Researchers uncover how two mechano-sensing ion channels are essential to maintain healthy stem ...

Researchers Create a New Organoid With All Key Pancreas Cells

Dec. 2, 2024 — Researchers have developed a new organoid that mimics the human fetal pancreas, offering a clearer view of its early development. The researchers were able to recreate a complete structure that ...

Mouse Study Captures Aging Process at the Cellular Level

Dec. 2, 2024 — As muscles age, their cells lose the ability to regenerate and heal after injury. Now, researchers have created the most comprehensive portrait to date of how that change, in mice, unfolds over ...

Scientists Identify Important Factor in Neural Development

Nov. 26, 2024 — Scientists have shed new light on how certain biological processes determine the development of neural cells. Their findings on a molecular 'bridge' complex demonstrate a new level of ...

Chromosomal Chaos Promotes Therapy Resistance in Leukemia Cells and Opens Up New Treatment Approaches

Nov. 25, 2024 — Chromosomal instability plays a crucial role in the progression of cancer: it shapes the properties of tumor cells and drives the development of therapy resistance. Scientists used state-of-the-art ...

Scientists Recreate Mouse from Gene Older Than Animal Life

Nov. 18, 2024 — An international team of researchers has achieved an unprecedented milestone: the creation of mouse stem cells capable of generating a fully developed mouse using genetic tools from a unicellular ...

Human Stem Cell-Derived Heart Cells Are Safe in Monkeys, Could Treat Congenital Heart Disease

Nov. 13, 2024 — A research team reported recently that heart muscle cells grown from induced pluripotent stem cells can integrate into the hearts of monkeys with a state of pressure ...

Researchers Home in on Tumor Vulnerabilities to Improve Odds of Treating Glioblastoma

Nov. 4, 2024 — Researchers have uncovered new targets that could be the key to effectively treating glioblastoma, a lethal type of brain cancer. These targets were identified through a screen for genetic ...

Space: A New Frontier for Exploring Stem Cell Therapy

Nov. 4, 2024 — Stem cells grown in microgravity aboard the International Space Station (ISS) have unique qualities that could one day help accelerate new biotherapies and heal complex disease, researchers say. The ...

Researchers Challenge Longstanding Theories in Cellular Reprogramming

Nov. 1, 2024 — A team led by researchers has discovered that a group of cells located in the skin and other areas of the body, called neural crest stem cells, are the source of reprogrammed neurons found by other ...

Researchers Identify Key Mechanism in Human Lung Development

Oct. 31, 2024 — Researchers have shown that the IGFBP3 protein plays a relevant role in human lung development. The results of the study, which used organoids derived from embryonic lungs, open up new perspectives ...

Keeping Close Watch on Stem Cells

Oct. 30, 2024 — Researchers have developed a new imagining system to monitor pluripotent stem cells during incubation. The new device -- INSPCTOR -- uses lens-free imaging technology integrated with thin-film ...

'Black Box' of Stem Cell Transplants Opened in Blood Study

Oct. 30, 2024 — New research into the long-term dynamics of transplanted stem cells in a patient's body explains how age affects stem cell survival and immune diversity, offering insights that could make ...

Immune Cell Discovery Offers New Potential for Cancer Immunotherapy

Oct. 25, 2024 — Researchers have identified a novel type of immune cell, called the stem-like CD4 T cell, that plays a pivotal role in anti-tumor immunity. The pre-clinical findings highlight the potential to ...