Pharmacology News

November 30, 2025

Top Headlines

Your Skin Has a Built-in Cancer Defense and Sunlight Turns It Off

Nov. 30, 2025 Scientists have uncovered how too much sunlight can flip a hidden switch inside skin cells that makes inflammation spiral out of control and increases the risk of cancer. Their research reveals that UV radiation breaks down a protective protein ...

Hidden Blood Molecules Show Surprising Anti-aging Power

Nov. 29, 2025 Scientists have identified new anti-aging compounds produced by a little-studied blood bacterium. These indole metabolites were able to reduce inflammation, oxidative stress, and collagen-damaging activity in skin cell cultures. Three of the ...

Scientists Find Toxic Metals Hidden in Popular Plastic Toys

Nov. 28, 2025 A large-scale Brazilian study found dangerous levels of toxic metals in popular children’s toys, with barium and lead topping the list. Researchers used sophisticated lab methods to identify 21 hazardous elements and test how easily they could be ...

Nov. 28, 2025 A major review across 73 countries finds that access to antiseizure medications is rising, but safe prescribing isn’t keeping pace. Valproate—linked to serious birth defects—remains widely used in many regions despite WHO warnings. Limited ...

Bird Flu’s Surprising Heat Tolerance Has Scientists Worried

Nov. 28, 2025 Researchers discovered why bird flu can survive temperatures that stop human flu in its tracks. A key gene, PB1, gives avian viruses the ability to replicate even at fever-level heat. Mice experiments confirmed that fever cripples human-origin flu ...

New Study Shows Rheumatoid Arthritis Begins Long Before Symptoms

Nov. 26, 2025 Rheumatoid arthritis begins years before pain ever appears, and scientists have now mapped the hidden immune battle that unfolds long before symptoms. By studying people with RA-linked antibodies over seven years, researchers discovered sweeping ...

One Protein May Hold the Key to Fixing Leukemia Treatment Failure

Nov. 24, 2025 Scientists have uncovered how leukemia cells manage to escape one of the most commonly used treatments. Over time, these cancer cells subtly change the shape of their mitochondria to avoid dying when the drug tries to kill them. By identifying the ...

Immune Cells Use a Surprising Trick to Heal Muscle Faster

Nov. 24, 2025 A research team has found that specific immune cells can connect with muscle fibers in a lightning-fast, neuron-like way to promote healing. These cells deliver quick pulses of calcium, triggering repair within seconds. The mechanism works in both ...

A Tiny Enzyme May Hold the Key to Safer Pain Relief

Nov. 23, 2025 Researchers have uncovered a surprising way the brain switches pain on, revealing that neurons can release an enzyme outside the cell that activates pain signals without disrupting normal movement or sensation. This enzyme, called VLK, modifies ...

New Nasal Nanodrops Wipe Out Brain Tumors in Mice

Nov. 22, 2025 A new nasal-delivered nanotherapy shows promise against aggressive glioblastoma tumors. By activating the STING immune pathway using gold-core spherical nucleic acids, researchers were able to reach the brain without invasive surgery. When paired ...

Scientists Reveal a Hidden Hormone Switch for Learning

Nov. 21, 2025 Researchers uncovered how estrogen subtly reshapes learning by strengthening dopamine reward signals in the brain. Rats learned faster when estrogen levels were high and struggled when the hormone’s activity was blocked. The findings help explain ...

New Evidence Shows Tirzepatide and Semaglutide Strongly Protect the Heart

Nov. 21, 2025 A massive real-world study comparing tirzepatide and semaglutide reveals both drugs deliver strong, early cardiovascular protection—reducing heart attack, stroke, and death in adults with type 2 diabetes. While companies have claimed large ...

Latest Headlines

updated 11:21am EST

Millions Are About to Choose the Wrong Medicare Plan

Nov. 29, 2025 Millions face Medicare decisions each year, but many don’t take advantage of tools that can save them money and stress. Insurance marketing often overshadows unbiased options like SHIP, leaving ...

Simple Amino Acid Supplement Greatly Reduces Alzheimer’s Damage

Nov. 21, 2025 Researchers discovered that the common amino acid arginine can block harmful Aβ aggregation and reduce its toxic effects in Alzheimer’s disease models. In flies and mice, oral arginine lowered ...

A Drug Already in Trials May Stop Chemotherapy Nerve Damage

Nov. 21, 2025 Researchers discovered that chemotherapy can accidentally trigger a stress alarm in immune cells, causing inflammation that damages nerves. Blocking this alarm protected mice from nerve pain and kept ...

Tiny Microneedle Patch Dramatically Improves Heart Attack Recovery

Nov. 21, 2025 Researchers created a dissolvable microneedle patch that delivers IL-4 directly to damaged heart tissue, jump-starting repair after a heart attack. The targeted approach shifts immune cells into a ...

Blocking a Single Protein Forces Cancer Cells to Self-Destruct

Nov. 20, 2025 Researchers uncovered a powerful weakness in lung cancer by shutting down a protein that helps tumors survive stress. When this protein, FSP1, was blocked, lung tumors in mice shrank dramatically, ...

Simple Molecule Shows Remarkable Alzheimer’s Reversal in Rats

Nov. 19, 2025 Scientists have developed a new molecule that breaks down beta-amyloid plaques by binding to excess copper in the brain. The treatment restored memory and reduced inflammation in rats, while also ...

Inflammation Turns Bone Marrow Into a Breeding Ground for Disease

Nov. 19, 2025 Researchers discovered that chronic inflammation fundamentally remodels the bone marrow, allowing mutated stem cell clones to quietly gain dominance with age. Reprogrammed stromal cells and ...

How to Keep Ozempic/Wegovy Weight Loss Without the Nausea

Nov. 18, 2025 Scientists are uncovering how GLP-1 drugs like Ozempic and Wegovy act on brain regions that control hunger, nausea, pleasure-based eating, and thirst. These discoveries may help create treatments ...

Scientists Discover Metformin May Block Key Exercise Benefits

Nov. 18, 2025 Rutgers scientists found that metformin can blunt many of the metabolic and cardiovascular improvements normally produced by exercise. Participants who took the drug saw reduced gains in fitness, ...

A Surprising CBD Advance Calms Pain Without Side Effects

Nov. 18, 2025 Researchers developed a new nano-micelle formulation, CBD-IN, that finally gets CBD into the brain effectively. In mice, it relieved neuropathic pain quickly and didn’t cause the usual movement or ...

Chronic Pain May Dramatically Raise Your Blood Pressure

Nov. 17, 2025 Chronic pain might quietly push people toward developing high blood pressure—and the more widespread the pain, the greater the danger. A massive analysis of over 200,000 adults uncovered strong ...

A Tiny Ancient Virus Reveals Secrets That Could Help Fight Superbugs

Nov. 17, 2025 Scientists mapped the Bas63 bacteriophage in unprecedented detail, uncovering how its tail machinery infects bacteria. The structure reveals rare whisker-collar features and distant evolutionary ties ...

Scientists Reverse Kidney Damage in Mice, Hope for Humans Next

Nov. 14, 2025 Researchers uncovered how fatty molecules called ceramides trigger acute kidney injury by damaging the mitochondria that power kidney cells. By altering ceramide metabolism or using a new drug ...

Strange Microscopic Structures Found in Long COVID Blood

Nov. 12, 2025 Scientists have discovered strange microscopic structures in the blood of people with Long COVID—clusters of tiny microclots tangled together with sticky immune webs known as neutrophil ...

Doctors Found a Way to Stop a Deadly Metformin Reaction

Nov. 9, 2025 A hospital in Thailand created a quick-action dialysis protocol for patients with metformin-associated lactic acidosis, a dangerous reaction to a common diabetes drug. The program sharply reduced ...

Scientists Find 15 Gut Bacteria That May Drive Heart Disease

Nov. 12, 2025 Scientists in Seoul have uncovered 15 gut bacterial species linked to coronary artery disease, showing that microbes can influence heart health far beyond digestion. Their findings reveal how shifts ...

A Tiny Worm Just Revealed a Big Secret About Living Longer

Nov. 13, 2025 Scientists studying aging found that sensory inputs like touch and smell can cancel out the lifespan-boosting effects of dietary restriction by suppressing the key longevity gene fmo-2. When ...

Scientists Shocked to Find E. Coli Spreads as Fast as the Swine Flu

Nov. 4, 2025 Researchers have, for the first time, estimated how quickly E. coli bacteria can spread between people — and one strain moves as fast as swine flu. Using genomic data from the UK and Norway, ...

DNA’s Hidden Power Could Transform How We Make Medicines

Nov. 8, 2025 Scientists found that DNA’s phosphate groups can direct chemical reactions to make the correct mirror-image form of drug molecules. This breakthrough simplifies chiral drug production, reducing ...

Think Melatonin Is Safe? New Research Reveals a Hidden Heart Risk

Nov. 4, 2025 Long-term melatonin use for sleep problems may come with unexpected heart dangers. Researchers found that chronic users were almost twice as likely to die and 3.5 times more likely to be hospitalized ...

A Groundbreaking Brain Map Could Revolutionize Parkinson’s Treatment

Nov. 3, 2025 Duke-NUS scientists unveiled BrainSTEM, a revolutionary single-cell map that captures the full cellular diversity of the developing human brain. The project’s focus on dopamine neurons provides ...

GLP-1 Drugs Like Ozempic Deliver Huge Weight Loss but New Research Reveals a Hidden Catch

Nov. 16, 2025 GLP-1 drugs like tirzepatide and semaglutide offer powerful weight-loss effects but come with unanswered questions about long-term safety, side effects, and global accessibility. Researchers stress ...

New Discovery Could Help Stop Diabetes Damage at Its Source

Nov. 15, 2025 Scientists identified a small molecule that interrupts a harmful protein pair linked to diabetic inflammation and tissue damage. The compound helped wounds heal faster and reduced organ stress in ...

Nanotech Makes Cancer Drug 20,000x Stronger, Without Side Effects

Nov. 5, 2025 A Northwestern team transformed a common chemotherapy drug into a powerful, targeted cancer therapy using spherical nucleic acids. The redesign dramatically boosted drug absorption and cancer-killing ...

Ancient Viruses Hidden Inside Bacteria Could Help Defeat Modern Infections

Nov. 3, 2025 Penn State scientists uncovered an ancient bacterial defense where dormant viral DNA helps bacteria fight new viral threats. The enzyme PinQ flips bacterial genes to create protective proteins that ...

A 25-Year Crohn’s Disease Mystery Finally Cracked by AI

Nov. 3, 2025 UC San Diego researchers combined artificial intelligence with molecular biology to unravel how immune cells in the gut decide between inflammation and healing, a process gone awry in Crohn’s ...

Scientists Find Hidden Antibiotic 100x Stronger Against Deadly Superbugs

Oct. 29, 2025 A team of scientists discovered a hidden antibiotic 100 times stronger than existing drugs against deadly superbugs like MRSA. The molecule had been overlooked for decades in a familiar bacterium. It ...

Ozempic and Wegovy Protect the Heart, Even Without Weight Loss

Oct. 31, 2025 Semaglutide appears to safeguard the heart even when patients lose little weight. In a massive international trial, heart attack and stroke risk dropped by 20% regardless of BMI. The benefit seems ...

Scientists Reveal the Best Exercise to Ease Knee Arthritis Pain

Oct. 20, 2025 A sweeping review of over 200 studies finds that aerobic exercises like walking and cycling offer the best pain relief and mobility gains for knee osteoarthritis. Compared to other types of exercise, ...

Can Ozempic Help You Cut Back on Alcohol? Researchers Think So

Oct. 18, 2025 Semaglutide, tirzepatide, and other GLP-1 drugs appear to slow alcohol absorption and blunt its intoxicating effects, according to new research. The study found participants on these medications felt ...