Pharmacology News

September 8, 2025

Top Headlines

Hidden Gut Cells Could Transform Food Allergy Treatment

Sep. 8, 2025 — Scientists have uncovered a surprising new pathway behind life-threatening food allergies. Instead of histamine, a different chemical called leukotrienes drives severe reactions in the gut. These molecules, released by specialized mast cells, ...

Scientists Just Made CRISPR Three Times More Effective

Sep. 7, 2025 — Northwestern scientists have developed a new nanostructure that supercharges CRISPR’s ability to safely and efficiently enter cells, potentially unlocking its full power to treat genetic diseases. By wrapping CRISPR’s tools in spherical ...

Strange New Bacteria Found in Amazon Sand Flies. Could It Spread to Humans?

Sep. 6, 2025 — A newly discovered species of Bartonella bacteria in Brazil’s Amazon sand flies shares DNA similarities with dangerous Andean strains. Scientists stress the need for further studies to see if it can infect humans and spread beyond its known ...

A Common Supplement Could Reverse the Hidden Harm of Sucralose

Sep. 6, 2025 — Sucralose, the sugar substitute in many diet products, may weaken cancer immunotherapy by altering gut bacteria and reducing arginine levels needed for immune cells. But supplementation with arginine or citrulline could counteract this effect, ...

Overworked Neurons Burn Out and Fuel Parkinson’s Disease

Sep. 3, 2025 — Overactivation of dopamine neurons may directly drive their death, explaining why movement-controlling brain cells degenerate in Parkinson’s. Mice with chronically stimulated neurons showed the same selective damage seen in patients, along with ...

Powerful New Painkiller ADRIANA Shows Promise in Ending Opioid Dependence

Sep. 2, 2025 — Japanese scientists have developed ADRIANA, a non-opioid painkiller that could provide powerful relief without the dangers of addiction. With successful trials already completed, large U.S. studies are now underway, raising hopes for a safer future ...

Common Heart Drug Taken by Millions Found Useless, Possibly Risky

Aug. 31, 2025 — Beta blockers, used for decades after heart attacks, provide no benefit for patients with preserved heart function, according to the REBOOT trial. The massive study also found women faced higher risks when taking the drug. Experts say the results ...

Beet Juice Secretly Helps Older Adults Lower Blood Pressure in Just Two Weeks

Aug. 31, 2025 — Drinking nitrate-rich beetroot juice lowered blood pressure in older adults by reshaping their oral microbiome, according to researchers at the University of Exeter. The study found that beneficial ...

Tiny Eye Implant Becomes the First FDA-approved Therapy for Rare Blindness

Aug. 29, 2025 — For people with macular telangiectasia type 2 (MacTel), an orphan retinal disorder that gradually destroys central vision, there have long been no approved treatment options. But now, a new study sponsored by Neurotech Pharmaceuticals and ...

Lithium Deficiency May Be the Hidden Spark Behind Alzheimer’s

Aug. 29, 2025 — Harvard scientists have uncovered that lithium, a naturally occurring element in the brain, may be the missing piece in understanding Alzheimer’s. Their decade-long research shows that lithium depletion—caused by amyloid plaques binding to ...

Scientists Crack Indole’s Toughest Bond with Copper, Unlocking New Medicines

Aug. 26, 2025 — Scientists have cracked one of chemistry’s toughest challenges with indoles, using copper to unlock a spot once thought too stubborn to change. The discovery could pave the way for easier, cheaper ...

The Surprising Reason X-rays Can Push Arthritis Patients Toward Surgery

Aug. 26, 2025 — Knee osteoarthritis is a major cause of pain and disability, but routine X-rays often do more harm than good. New research shows that being shown an X-ray can increase anxiety, make people fear exercise, and lead them to believe surgery is the only ...

Latest Headlines

updated 8:22am EDT

Common Painkillers Like Advil and Tylenol Supercharge Antibiotic Resistance

Aug. 26, 2025 — Painkillers we often trust — ibuprofen and acetaminophen — may be quietly accelerating one of the world’s greatest health crises: antibiotic resistance. Researchers discovered that these drugs ...

A Hidden Sugar Source in Ketchup, Salad Dressing, and Toothpaste

Aug. 25, 2025 — UBC researchers revealed that gut bacteria can digest cellulose-based food thickeners, once thought indigestible, by using enzymes activated by natural dietary fibers. This discovery suggests these ...

Tiny Green Tea Beads Trap Fat and Melt Away Pounds Without Side Effects

Aug. 24, 2025 — Researchers have created plant-based microbeads that trap fat in the gut, helping rats lose weight without side effects. Unlike current drugs, the beads are safe, tasteless, and easy to mix into ...

A Safe Painkiller? New Research Raises Concerns About Tylenol’s Safety in Pregnancy

Aug. 21, 2025 — A large-scale review finds that acetaminophen use during pregnancy may increase the risk of autism and ADHD in children. The strongest studies showed ...

Is Ketamine the Answer for Chronic Pain? New Findings Cast Doubt

Aug. 18, 2025 — A sweeping review of 67 trials has cast doubt on the use of ketamine and similar NMDA receptor antagonists for chronic pain relief. While ketamine is frequently prescribed off-label for conditions ...

Trojan Horse Bacteria Sneak Cancer-Killing Viruses Into Tumors

Aug. 17, 2025 — Scientists have engineered a groundbreaking cancer treatment that uses bacteria to smuggle viruses directly into tumors, bypassing the immune system and delivering a powerful one-two punch against ...

One Small Walking Adjustment Could Delay Knee Surgery for Years

Aug. 16, 2025 — A groundbreaking study has found that a simple change in walking style can ease osteoarthritis pain as effectively as medication—without the side effects. By adjusting foot angle, participants ...

The Parasite That Turns Off Your Body’s Pain Alarm and Sneaks in

Aug. 12, 2025 — Scientists have discovered a parasite that can sneak into your skin without you feeling a thing. The worm, Schistosoma mansoni, has evolved a way to switch off the body’s pain and itch signals, ...

Can a Diet Really Ease Lipoedema? Sunniva’s Journey to Pain Relief and Weight Loss

Aug. 10, 2025 — Sunniva Kwapeng struggled with lipoedema, a painful condition causing disproportionate fat accumulation, until finally being diagnosed in her 40s. An ...

Scientists Just Found a Tiny Molecule That Could Change How We Lose Weight

Aug. 10, 2025 — Researchers at the Salk Institute have used CRISPR to uncover hidden microproteins that control fat cell growth and lipid storage, identifying one confirmed target, Adipocyte-smORF-1183. This ...

Brain Fog, Falls, and Fatigue? This App Helps Seniors Cut Risky Meds

Aug. 5, 2025 — McGill's MedSafer tool helps doctors identify and eliminate risky or unneeded medications in seniors, significantly improving patient outcomes. It aims to prevent harmful "prescribing ...

This Sugar Molecule Could Stop Type 1 Diabetes, by Fooling the Immune System

Aug. 2, 2025 — In a fascinating twist, Mayo Clinic researchers discovered that a sugar molecule cancer cells use to hide from the immune system might also protect insulin-producing beta cells in type 1 diabetes. By ...

Found in the Trash: A Super Opioid 1000x Stronger Than Morphine

Aug. 1, 2025 — A powerful new synthetic opioid, up to 1000 times stronger than morphine, has emerged in Adelaide’s street drug supply, and researchers are sounding the alarm. Nitazenes, often hidden in heroin or ...

This Vaccine Uses Dental Floss Instead of Needles

Aug. 3, 2025 — Scientists have discovered that flossing between your teeth could one day help vaccinate you. By targeting a uniquely permeable gum tissue called the junctional epithelium, this new method stimulates ...

This New Drug Could Help PTSD Patients Finally Let Go of Trauma

Aug. 3, 2025 — Researchers discovered that PTSD may be driven by excess GABA from astrocytes, not neurons. This chemical imbalance disrupts the brain’s ability to forget fear. A new drug, KDS2010, reverses this ...

Pain Relief Without Pills? VR Nature Scenes Trigger the Brain’s Healing Switch

July 30, 2025 — Stepping into a virtual forest or waterfall scene through VR could be the future of pain management. A new study shows that immersive virtual nature dramatically reduces pain sensitivity almost as ...

Columbia Scientists Turn Yogurt Into a Healing Gel That Mimics Human Tissue

July 29, 2025 — Scientists at Columbia Engineering have developed an injectable hydrogel made from yogurt-derived extracellular vesicles (EVs) that could revolutionize regenerative medicine. These EVs serve both as ...

Millipedes Make Ants Dizzy — and Might Soon Treat Human Pain

July 25, 2025 — Millipedes, often dismissed as creepy crawlies, may hold the secret to future painkillers and neurological drugs. Researchers at Virginia Tech discovered unique alkaloid compounds in the defensive ...

The Plant Virus That Trains Your Immune System to Kill Cancer

July 25, 2025 — A virus from humble black-eyed peas is showing extraordinary promise in the fight against cancer. Unlike other plant viruses, the cowpea mosaic virus (CPMV) can awaken the human immune system and ...

People With Eating Disorders Say Cannabis and Psychedelics Help More Than Antidepressants

July 24, 2025 — A massive global survey has revealed that people with eating disorders often turn to cannabis and psychedelics like magic mushrooms and LSD to ease their symptoms, rating them more effective than ...

What Really Happens to Your Body When You Stop Weight Loss Drugs Like Ozempic

Aug. 7, 2025 — Stopping prescription weight loss drugs often leads to significant weight regain, according to a large-scale analysis of 11 global studies. Researchers found that although these medications, ...

Fat Melts Away, but So Does Muscle: What Ozempic Users Need to Know

July 30, 2025 — GLP-1 drugs like Ozempic are transforming weight loss, but a new UVA study warns they're not improving a critical measure of health: cardiorespiratory fitness. While these medications help ...

This Sugar Substitute Does More Than Sweeten — It Kills Cancer Cells

July 25, 2025 — Fermenting stevia with a banana leaf-derived probiotic turns it into a powerful cancer-fighting agent that kills pancreatic cancer cells while sparing healthy ones. The secret lies in a metabolite ...

One Pregnancy Shot Slashes Baby RSV Hospitalizations by 72% — and Shields for Months

July 21, 2025 — A new UK study shows that vaccinating pregnant women against RSV has led to a staggering 72% drop in hospitalizations of newborns with severe lung infections. By passing virus-fighting antibodies to ...

A Tiny Chemistry Hack Just Made mRNA Vaccines Safer, Stronger, and Smarter

July 21, 2025 — What if mRNA vaccines could be made more powerful and less irritating? Scientists at the University of Pennsylvania have found a way to do just that—by tweaking a key molecule in the vaccine’s ...

Three-Person DNA IVF Stops Inherited Disease—eight Healthy Babies Born in UK First

July 18, 2025 — In a groundbreaking UK first, eight healthy babies have been born using an IVF technique that includes DNA from three people—two parents and a female donor. The process, known as pronuclear ...

Science Tested 64 Natural Remedies for Depression—only a Few Actually Work

July 28, 2025 — Over-the-counter (OTC) products like St John’s Wort and omega-3s have long been touted for helping with depression, but new research reveals that 64 different OTC products have been tested in ...

This Bedtime Snack Swap Could Rewire Your Gut and Help Prevent Diabetes

July 24, 2025 — A new study reveals that swapping a typical nighttime carbohydrate snack for pistachios may beneficially alter gut bacteria in people with prediabetes. Conducted by Penn State researchers, the ...

One Shot, Seven Days: Long-Acting Levodopa Gel Tackles Parkinson’s Tremors

July 14, 2025 — Researchers in Australia have created a biodegradable gel that delivers Parkinson’s medications through a single weekly shot, replacing the need for multiple daily pills. Injected just under the ...

Weight-Loss Wonder Drug Mounjaro/Zepbound Shrinks Breast Cancer Tumors

July 15, 2025 — A cutting-edge mouse study reveals that tirzepatide, the dual GLP-1/GIP drug already hailed for impressive weight loss, does more than trim fat: it slashes the growth of obesity-linked breast tumors. ...