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Reference Terms
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Psychopharmacology

Psychopharmacology is the study of drug-induced changes in mood, thinking, and behavior. These drugs may originate from natural sources such as plants and animals, or from artificial sources such as chemical syntheses in the laboratory. These drugs interact with particular target sites or receptors found in the nervous system to induce widespread changes in physiological or psychological functions. The specific interaction between drugs and their target sites or receptors is referred to as drug action. The widespread changes in physiological or psychological function is referred to as drug effect. In psychopharmacology, researchers are interested in a wide range of drug classes such as antidepressants and stimulants. Drugs are researched for their pharmaceutical properties, physical side effects, and psychological side effects.

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Mind & Brain News

November 16, 2025

Researchers found that tau proteins don’t jump straight into forming Alzheimer’s-associated fibrils—first they assemble into soft, reversible clusters. When the clusters were dissolved, fibril growth was almost entirely suppressed. This ...
Researchers have uncovered surprising evidence that anxiety may be controlled not by neurons but by two dueling groups of immune cells inside the brain. These microglia act like biological pedals—one pushing anxiety forward and the other holding ...
Japanese researchers found that lecanemab, an amyloid-clearing drug for Alzheimer’s, does not improve the brain’s waste clearance system in the short term. This implies that nerve damage and impaired clearance occur early and are difficult to ...
Researchers identified SGK1 as a key chemical connecting childhood trauma to depression and suicidal behavior. High SGK1 levels were found in the brains of suicide victims and in people with genetic variants linked to early adversity. Drugs that ...
Millions struggle with depression and anxiety, often enduring long waits for effective treatment. Scientists in Sweden, Denmark, and Germany are developing a genetic test to predict which medications will actually work. Using polygenic risk scores, ...
Sertraline (Zoloft) may relieve emotional symptoms of depression and anxiety within two weeks, while physical side effects stabilize later. The research highlights how antidepressants can act on specific symptom networks rather than uniformly across ...
Researchers have identified special immune cells in the brain that help slow Alzheimer’s. These microglia work to reduce inflammation and block the spread of harmful proteins. They appear to protect memory and brain health, offering a promising ...
Prenatal exposure to the insecticide chlorpyrifos causes widespread brain abnormalities and poorer motor skills in children. Even after a residential ban, ongoing agricultural use continues to endanger developing ...
Miniature antibodies from camels and llamas can slip into the brain more easily than conventional drugs, offering a new way to treat disorders like Alzheimer’s and schizophrenia. Researchers say these “nanobodies” could reshape the future of ...
Scientists have discovered a surprising benefit of the acne drug doxycycline: it may lower the risk of schizophrenia. Teens prescribed the antibiotic were about one-third less likely to develop the condition as adults. The effect could stem from the ...
Weill Cornell researchers uncovered how free radicals from astrocyte mitochondria can fuel dementia. Using new compounds that target these radicals at their source, they slowed brain inflammation and neuronal damage in mice. The findings reveal a ...
Virginia Tech researchers have shown that memory loss in aging may be reversible. Using CRISPR tools, they corrected molecular disruptions in the hippocampus and amygdala, restoring memory in older rats. Another experiment revived a silenced memory ...

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