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Opium News

August 31, 2026

Top Headlines

 

Researchers discovered a brain-based “brake” that can shut down chronic nerve pain in mice by calming an overactive pain circuit. Targeting this system more precisely could one day lead to powerful pain relief without affecting opioid receptors ...
Ozempic-like drugs appear to weaken more than hunger—they may also reduce cravings for alcohol and other addictive substances. Scientists are increasingly tracing this effect to the lateral septum, a brain region that helps connect memories and ...
An intensive seven-day meditation retreat triggered striking changes across the brain and body, including shifts tied to neuroplasticity, immunity, metabolism, and natural pain relief. Participants also showed brain connectivity patterns resembling ...
A new experimental vaccine developed by Scripps Research could offer a powerful new way to prevent fentanyl overdoses by stopping the drug before it reaches the brain. Rather than targeting only fentanyl itself, the vaccine trains the immune system ...
Cannabis use among older adults is rising fast, but today’s marijuana is far more potent than many people realize — and experts warn the risks may be underestimated. Stanford Medicine specialists ...
Scientists have developed a new gene therapy that quiets pain at its source in the brain—without the addictive risks of opioids. Using AI to map how pain is processed, they created a targeted “off switch” that mimics morphine’s benefits but ...
Cocaine addiction isn’t simply a failure of willpower — it’s the result of lasting biological changes in the brain. Researchers at Michigan State University discovered that repeated cocaine use rewires communication between the brain’s ...
GLP-1 drugs, originally developed for diabetes and obesity, may also curb addictive behaviors by acting on reward circuits in the brain. Early trials show reductions in alcohol intake, opioid seeking, and nicotine use. Though more research is ...
Addiction often isn’t about chasing pleasure—it’s about escaping pain. Researchers at Scripps Research have discovered that a tiny brain region called the paraventricular nucleus of the ...
Japanese scientists have developed ADRIANA, a non-opioid painkiller that could provide powerful relief without the dangers of addiction. With successful trials already completed, large U.S. studies are now underway, raising hopes for a safer future ...
A breakthrough drug from Duke University, SBI-810, promises strong pain relief without the pitfalls of opioids. Unlike traditional painkillers that trigger multiple brain pathways—and often addiction—SBI-810 activates just one specific pathway ...
Ketamine addiction is linked to high levels of physical health problems and psychological consequences, with nearly half of those affected not seeking support or treatment, new research has ...

Latest Headlines

updated 8:16am EDT

Earlier Headlines

 

With the goal of informing clinician practice, a new study explores the harms and benefits of continuing and of discontinuing the long-term prescription of opioid medicines to adults with chronic ...

In the face of the alarming number of opioid-related deaths in the U.S., there have been national efforts to increase emergency clinician prescribing of buprenorphine, a medication used to treat ...

Who hasn't been there? The big meal is over, you're full, but the craving for sweets remains. Researchers have now discovered that what we call the 'dessert stomach' is rooted in ...

A new study found no changes in opioid outcomes among the general population with the states' passage of medical and recreational marijuana laws. However, the findings also show decreases in ...

Researchers find an over-the-counter combo is more effective for wisdom tooth extraction ...

Researchers have made a discovery regarding the TRPV1 (transient receptor potential vanilloid 1) ion channel and its role in pain perception. The study reveals how solvent molecules can modulate pain ...

Researchers found that adolescents with more symptoms of gaming addiction showed lower brain activity in the region involved in decision-making and reward processing; this blunted response to reward ...

Increasing the levels of chemicals naturally produced in the body called endocannabinoids may thwart the highly addictive nature of opioids such as morphine and oxycodone while maintaining the ...

Research shows that reward-based learning requires the two neuromodulators to balance one another's influence -- like the accelerator and brakes on a ...

Neuroscientists have identified the binding site of low-dose ketamine, providing critical insight into how the medication, often described as a wonder drug, alleviates symptoms of major depression in ...

Evidence has been growing to suggest that tetrahydrocannabinol (THC), the main psychoactive ingredient in cannabis, poses risks to the developing fetus by impacting brain development. Now a new ...

People with opioid use disorder in British Columbia who received methadone had a 37- to 40-percent lower rate of treatment discontinuation compared with those who received buprenorphine/naloxone. The ...

According to new research, men and women rely on different biological systems for pain relief, which could help explain why our most powerful pain medications are often less effective in ...

Opioid drugs are highly effective at relieving pain but come with severe drawbacks. Their side effects range from dizziness to potentially fatal respiratory depression. Their illegal use contributes ...

Adults with opioid use disorder who receive a higher daily dose of the opioid addiction treatment medication buprenorphine may have a lower risk of subsequent emergency department visits or use of ...

New findings argue against a direct causal role for dopamine during the experience of a treatment effect in the establishment of positive treatment expectations and placebo analgesia in healthy ...

Drug overdose mortality has risen faster among adolescents than the general population in recent years, largely due to fentanyl, a potent opioid pain medication. A new study sheds light on trends in ...

A pilot study showed that a small amount of ketamine can reduce or eliminate the withdrawal symptoms associated with quitting ...

Researchers describe the neural processes behind how morphine relieves pain. This is valuable knowledge because the drug has such serious side ...

A new study that details trends among psychiatric hospitalizations between 2015-2019 finds that while most hospitalizations did not involve any substances, methamphetamine-related hospitalizations ...

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