Sickle Cell Anemia News
February 24, 2025
Top Headlines
Jan. 17, 2025 — A new study has found older-looking brains in adults with sickle cell disease, helping to explain the cognitive challenges experienced by such individuals. A brain image from a healthy individual (left) shows a larger brain with more white matter ...
Sep. 12, 2024 — Researchers have found that being a carrier for sickle cell disease, known as having sickle cell trait, increases the risk of blood clots, a risk that is the same among diverse human populations that ...
Sep. 9, 2024 — Sickle cell disease is a common genetic disorder characterized by periodic occurrences of pain which happen repeatedly through life. These episodes, referred to as a vaso-occlusive episodes, happen ...
July 31, 2024 — Researchers found a small molecule that increases fetal hemoglobin production in human blood stem cells and leads to fewer sickled red blood cells in mice, providing proof of principle for developing ...
Latest Headlines
updated 10:19am EST
Jan. 30, 2025 — A systematic literature review found no evidence to support that physical exertion without rhabdomyolysis (muscle breakdown) or heat injury can cause sudden death for individuals with sickle cell ...
Sep. 20, 2024 — The incidence of stroke continues to increase for adults and children living with sickle cell disease (SCD) despite the Stroke Prevention Trial in ...
Sep. 19, 2024 — A research team has discovered a mechanism in which blood stem cells respond to acute, severe anemia, through lipoprotein metabolism modification. It has been known how immediate erythroid precursors ...
July 25, 2024 — In a rigorous medical records study covering tens of thousands of patients, researchers conclude that some patients with preoperative anemia have ...
Jan. 29, 2024 — Researchers have revealed that hydroxyurea significantly reduces infections in children with sickle cell anemia. Their findings enhance strong ...
Nov. 16, 2023 — Researchers have discovered that 'cell competition' following gene therapy results in the accumulation of stem cells with genetic mutations which make them grow faster. Some of these genetic ...
Nov. 14, 2023 — A team has mapped the location and spatial features of blood-forming cells within human bone marrow. Their findings confirm hypotheses about the anatomy of this tissue and provide a powerful new ...
Aug. 30, 2023 — A clinical trial has tested a potentially curative stem cell gene therapy for sickle cell disease. The results were ...
Aug. 9, 2023 — A study shows new steps toward more patients getting gene ...
July 27, 2023 — In a step forward in the development of genetic medicines, researchers have developed a proof-of-concept model for delivering gene editing tools to ...
Earlier Headlines
Apr. 11, 2024 — A drug approved to treat pulmonary arterial hypertension may be effective at managing hypertension and end-organ damage in patients with sickle cell disease, according to a new study. An early phase ...
May 4, 2023 — A major challenge in human genetics is understanding which parts of the genome drive specific traits or contribute to disease risk. This challenge is even greater for genetic variants found in the ...
Apr. 17, 2023 — Scientists showed how prime editing can correct mutations that cause sickle cell disease in a potentially curative ...
Mar. 16, 2023 — While research has long established disparities in health outcomes among individuals living with sickle cell disease (SCD), few studies have quantified these gaps. A new study finds that the average ...
Jan. 30, 2023 — Researchers have designed a microfluidic device, or 'spleen-on-a-chip,' that can model how the spleen's filters become clogged by sickled red blood cells, leading to a life-threatening ...
Oct. 24, 2022 — Researchers are working to reveal potential threats to the efficacy of CRISPR/Cas9 gene editing, even when it appears to be working as ...
Oct. 12, 2022 — Scientists found the cellular response to low oxygen also increases fetal hemoglobin expression in adults, which could lead to novel treatments for some common genetic ...
Apr. 14, 2022 — Results from a phase 3 clinical indicate that the oral drug mitapivat is safe and effective for treating adults with pyruvate kinase deficiency, a genetic condition that causes red blood cell ...
Apr. 8, 2022 — Researchers have used CRISPR gene editing -- a type of 'molecular scissors' -- to understand how deletions in one area of the genome can affect the expression of nearby genes. The work will ...