Liver Disease News

March 20, 2025

Top Headlines

Mother's High-Fat Diet Can Cause Liver Stress in Fetus

Mar. 13, 2025 — When mothers eat a diet high in fat and sugars, their unborn babies can develop liver stress that continues into early life. A new study sheds light on changes to the fetus's bile acid, which affects how liver disease develops and ...

Secret Boss of the Liver: Star-Shaped Cells That Promote Fibrosis Also Regulate Liver Health

Mar. 12, 2025 — New research suggests restoring stellate cells to their healthy and protective state could simultaneously reduce liver scarring and improve liver ...

Hepatic Stellate Cells Control Liver Function and Regeneration

Mar. 12, 2025 — Until now, doctors knew hepatic stellate cells mainly as drivers of liver fibrosis. The actual functions of this cell type have hardly been studied to date. Researchers have now determined that hepatic stellate cells control liver metabolism as well ...

Nwd1 Gene Deletion Triggers MASH-Like Pathology in Mice

Mar. 11, 2025 — Metabolic dysfunction-associated steatohepatitis (MASH) is a polygenic disorder influenced by multiple genes, but their specific roles in the progression of disease remain unknown. To address this gap, researchers conducted a series of experiments ...

Latest Headlines

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Ammonia Build-Up Kills Liver Cells but Can Be Prevented Using Existing Drug

Mar. 7, 2025 — High levels of ammonia kill liver cells by damaging the mitochondria that power the cells. But this can be prevented using an existing drug due to start clinical trials, finds a new study in ...

Researchers Identify a Gene to Guide Novel Therapeutics of Nonalcoholic Fatty Liver Diseases

Mar. 6, 2025 — Investigators have found that the gene Asah1 plays a crucial protective role in preventing the progression of nonalcoholic fatty liver diseases ...

Interventions Identified to Eliminate Transmission of Hepatitis B in Africa

Feb. 27, 2025 — A new study that has the potential to change the landscape of hepatitis B transmission in Africa. Researchers conducted an analysis revealing key interventions that could effectively eliminate ...

New Study Offers Hope to Patients With Advanced Liver Cancer, Cirrhosis

Feb. 10, 2025 — Researchers describe successful tumor removal through the use of immunotherapy and targeted radiation therapy (TARE), in a patient previously considered ineligible for the ...

Why Some Heavy Drinkers Develop Advanced Liver Disease, While Others Do Not

Feb. 6, 2025 — The research found that heavy drinkers with either diabetes, high blood pressure or a high waist circumference are as much as 2.4 times more likely to develop advanced liver ...

Low-Level Traffic Air Pollution Linked to Liver Damage and Fatty Liver Disease

Jan. 31, 2025 — Low levels of traffic-related air pollution harms the liver and may raise the risk of metabolic-associated fatty liver disease, a new study in mice ...

Weight-Loss Surgery Lowers Risk of Developing Complications of Liver Disease in Patients With Cirrhosis and Obesity

Jan. 27, 2025 — A study shows that patients with obesity and fatty liver-related cirrhosis who had bariatric (weight-loss) surgery significantly lowered their future ...

Shiitake-Derived Functional Food Shows Suppression of Liver Fibrosis Progression

Dec. 19, 2024 — A research team found out how AHCC, a standardized extract of cultured Lentinula edodes mycelia, might be able to suppress the progression of liver ...

Combined Screening Can Detect Liver Damage in Diabetes Patients

Dec. 13, 2024 — New research highlights the possibility of screening people with type 2 diabetes for liver damage at the same time as they undergo screening for eye ...

Updated Hep B Vaccine More Effective for People With HIV

Dec. 10, 2024 — A newer vaccine against hepatitis B virus was clearly superior to an older vaccine type in inducing a protective antibody response among people living with HIV who didn't respond to prior ...

Researchers Find That Intestinal Infections Change Bile Composition

Nov. 26, 2024 — Researchers have identified a new axis of host defense by studying what happens during enteric infection -- a term that encompasses all types of intestinal infections including so called ...

Scientists Implicate a Novel Cellular Protein in Hepatitis A Infection

Nov. 21, 2024 — Scientists have long been trying to tease apart hepatitis A virus, to understand its inner workings and how it functions in the human body. Infectious disease researchers have discovered that a ...

Microbiome Changes in Chronic Liver Disease Highlight the Need for Personalized Treatment

Nov. 18, 2024 — People with chronic liver disease have dramatic changes to the types and functions of bacteria in the gut and mouth, a new study has ...

Cell Aging in One Organ Can Snowball Into Multi-Organ Failure

Nov. 13, 2024 — The aging and failure of cells that occurs when one part of the body is damaged can spread to other organs, a study ...

Mouse Model Reveals Liver Involvement in Muscular Dystrophy

Oct. 24, 2024 — A new mouse model mimicking the liver symptoms of myotonic dystrophy type 1 -- the most prevalent form of adult-onset muscular dystrophy -- provides insight into why patients develop fatty liver ...

A Novel Approach to Combat Fatty Liver Disease

Oct. 9, 2024 — Blocking the enzyme ACMSD can significantly reduce damage caused by metabolic liver disease according to a new ...

Balancing Health: Diabetes and Obesity Increase Risk of Liver Cancer Relapse

Oct. 3, 2024 — A research team analyzed how diabetes mellitus and obesity factor into recurrence and survival after surgery for hepatocellular carcinoma, a type of liver ...

Researchers Identify Potential New Strategy to Slow the Development of Liver Fibrosis

Sep. 17, 2024 — A study reveals advances in the understanding and treatment of liver fibrosis, a serious complication in the context of metabolic fatty liver disease, also known as MASLD (metabolic ...

Finding New Targets for Blocking Chronic Hepatitis

Aug. 29, 2024 — Researchers revealed how certain liver cells contribute to inflammatory responses underlying chronic hepatitis. Using mouse and cell culture models, they observed increased levels of inflammatory ...

Macrophage Mix Helps Determine Rate and Fate of Fatty Liver Disease

Aug. 22, 2024 — The white blood cells' typical role is to promote inflammation and stimulate the immune response, but researchers say some actually appear to temper inflammatory conditions and improve ...

Hepatic Disease: A Camu-Camu Fruit Extract to Reduce Liver Fat

Aug. 21, 2024 — A research team has shown the benefits of camu-camu on non-alcoholic fatty liver disease. This exotic fruit reduces liver fat ...

Liver Transplant Outperforms Other Therapies for Colorectal Cancer That Has Spread to the Liver

July 30, 2024 — A study followed patients whose colorectal cancer was under control, but who had liver tumors that could not be surgically removed. All patients were eligible for liver transplantation, but some ...

Study Finds Targeting Inflammation May Not Help Reduce Liver Fibrosis in MAFLD

July 26, 2024 — Researchers uncovered new information about the role inflammation plays in mitigating liver fibrosis, which is associated with metabolic-associated fatty liver disease (MAFLD), one of the most common ...

New Research in Fatty Liver Disease Aims to Help With Early Intervention

July 25, 2024 — A new study brings researchers closer to better understanding the pathology of the fatty liver disease MASH, which stands for metabolic dysfunction-associated steatohepatitis. MASH is a consequence ...

Paleolithic Diets Are Not Without Risks

July 17, 2024 — High-protein diets, known as 'Paleolithic diets', are popular. Using mouse models, scientists have studied their impact. While effective in regulating weight and stabilizing diabetes, these ...

Cirrhosis Affects Twice as Many Transgender Adults as Cisgender Adults, Study Finds

July 10, 2024 — A new study has found a startling disparity in the frequency of liver disease for transgender individuals and highlights the need for more specialized ...

Hepatitis B: 'Sleep Timer' for Immune Cells Discovered

July 10, 2024 — In chronic hepatitis B, the liver contains immune cells that could destroy hepatitis B virus infected cells but are inactive. Researchers have discovered that cells blood vessels in the liver start a ...

Study Shows How Liver Damage from Stress and Aging Might Be Reversible

June 26, 2024 — While the liver is one of the body's most resilient organs, it is still vulnerable to the ravages of stress and aging, leading to disease, severe scarring and failure. A research team now might ...

New Screening Tool Could Improve the Survival Rate of Patients With Hepatocellular Carcinoma from 20% to 90%

June 17, 2024 — Early diagnosis of hepatocellular carcinoma (HCC) -- one of the most fatal malignancies -- is crucial to improve patient survival. In a breakthrough study investigators report on the development of a ...

New Approach Against Fatty Liver

June 14, 2024 — Fatty liver disease (steatotic liver disease, SLD for short) is increasingly causing failure of the liver as a vital organ. A team led by researchers has now discovered that a saturated fatty acid in ...