Liver Disease News

June 3, 2025

Top Headlines

Pancreatic Cancer Spreads to Liver or Lung Thanks to This Protein

June 3, 2025 — Scientists have discovered how pancreatic cancer cells thrive in the lungs or liver, environments that are as distinct to cells as the ocean and desert are to animals. The spread of cancer cells to organs like these often produces the very first ...

All-in-One Model Reconstructs Complex Liver Architecture

May 29, 2025 — The liver has a unique structure, especially at the level of individual cells. Hepatocytes, the main liver cells, release bile into tiny channels called bile canaliculi, which drain into the bile duct in the liver periportal region. When this bile ...

Scientists Discover Key Gene Impacts Liver Energy Storage, Affecting Metabolic Disease Risk

May 16, 2025 — A new study reveals that a single gene plays a big role in how the liver stores energy, a process that's critical for overall health and for managing diseases like type 2 diabetes. The research ...

Research Shows How Hormone Can Reverse Fatty Liver Disease in Mice

May 14, 2025 — A pioneering research study details how the hormone FGF21 (fibroblast growth factor 21) can reverse the effects of fatty liver disease in mice. The hormone works primarily by signaling the brain to improve liver ...

Latest Headlines

updated 10:43pm EDT

Liver Cancer Survival Rates Reflect Income Disparities

May 5, 2025 — The risk of dying from the most common form of primary liver cancer is about 30 percent higher for patients with low household income compared to those with middle or high household income, according ...

Semaglutide Treats Liver Disease in Two Thirds of Patients

Apr. 30, 2025 — Semaglutide effectively treats liver disease in two thirds of patients, new research has ...

New Human 'Multi-Zonal' Liver Organoids Improve Injury Survival in Rodents

Apr. 16, 2025 — 'Multi-zonal' liver organoids represent a significant step forward in developing lab-grown liver ...

Fatty Liver Linked to Increased Risk of Death from Several Diseases

Mar. 24, 2025 — A comprehensive study shows that people with fatty liver disease have almost twice the mortality rate of the general population. They have an increased risk of dying from both liver diseases and ...

Mother's High-Fat Diet Can Cause Liver Stress in Fetus

Mar. 13, 2025 — When mothers eat a diet high in fat and sugars, their unborn babies can develop liver stress that continues into early life. A new study sheds light on changes to the fetus's bile acid, which affects ...

Secret Boss of the Liver: Star-Shaped Cells That Promote Fibrosis Also Regulate Liver Health

Mar. 12, 2025 — New research suggests restoring stellate cells to their healthy and protective state could simultaneously reduce liver scarring and improve liver ...

Hepatic Stellate Cells Control Liver Function and Regeneration

Mar. 12, 2025 — Until now, doctors knew hepatic stellate cells mainly as drivers of liver fibrosis. The actual functions of this cell type have hardly been studied to date. Researchers have now determined that ...

Nwd1 Gene Deletion Triggers MASH-Like Pathology in Mice

Mar. 11, 2025 — Metabolic dysfunction-associated steatohepatitis (MASH) is a polygenic disorder influenced by multiple genes, but their specific roles in the progression of disease remain unknown. To address this ...

Ammonia Build-Up Kills Liver Cells but Can Be Prevented Using Existing Drug

Mar. 7, 2025 — High levels of ammonia kill liver cells by damaging the mitochondria that power the cells. But this can be prevented using an existing drug due to start clinical trials, finds a new study in ...

Researchers Identify a Gene to Guide Novel Therapeutics of Nonalcoholic Fatty Liver Diseases

Mar. 6, 2025 — Investigators have found that the gene Asah1 plays a crucial protective role in preventing the progression of nonalcoholic fatty liver diseases ...

Interventions Identified to Eliminate Transmission of Hepatitis B in Africa

Feb. 27, 2025 — A new study that has the potential to change the landscape of hepatitis B transmission in Africa. Researchers conducted an analysis revealing key interventions that could effectively eliminate ...

New Study Offers Hope to Patients With Advanced Liver Cancer, Cirrhosis

Feb. 10, 2025 — Researchers describe successful tumor removal through the use of immunotherapy and targeted radiation therapy (TARE), in a patient previously considered ineligible for the ...

Why Some Heavy Drinkers Develop Advanced Liver Disease, While Others Do Not

Feb. 6, 2025 — The research found that heavy drinkers with either diabetes, high blood pressure or a high waist circumference are as much as 2.4 times more likely to develop advanced liver ...

Low-Level Traffic Air Pollution Linked to Liver Damage and Fatty Liver Disease

Jan. 31, 2025 — Low levels of traffic-related air pollution harms the liver and may raise the risk of metabolic-associated fatty liver disease, a new study in mice ...

Weight-Loss Surgery Lowers Risk of Developing Complications of Liver Disease in Patients With Cirrhosis and Obesity

Jan. 27, 2025 — A study shows that patients with obesity and fatty liver-related cirrhosis who had bariatric (weight-loss) surgery significantly lowered their future risk of developing serious liver complications ...

Shiitake-Derived Functional Food Shows Suppression of Liver Fibrosis Progression

Dec. 19, 2024 — A research team found out how AHCC, a standardized extract of cultured Lentinula edodes mycelia, might be able to suppress the progression of liver ...

Combined Screening Can Detect Liver Damage in Diabetes Patients

Dec. 13, 2024 — New research highlights the possibility of screening people with type 2 diabetes for liver damage at the same time as they undergo screening for eye ...

Updated Hep B Vaccine More Effective for People With HIV

Dec. 10, 2024 — A newer vaccine against hepatitis B virus was clearly superior to an older vaccine type in inducing a protective antibody response among people living with HIV who didn't respond to prior ...

Researchers Find That Intestinal Infections Change Bile Composition

Nov. 26, 2024 — Researchers have identified a new axis of host defense by studying what happens during enteric infection -- a term that encompasses all types of intestinal infections including so called ...

Scientists Implicate a Novel Cellular Protein in Hepatitis A Infection

Nov. 21, 2024 — Scientists have long been trying to tease apart hepatitis A virus, to understand its inner workings and how it functions in the human body. Infectious disease researchers have discovered that a ...

Microbiome Changes in Chronic Liver Disease Highlight the Need for Personalized Treatment

Nov. 18, 2024 — People with chronic liver disease have dramatic changes to the types and functions of bacteria in the gut and mouth, a new study has ...

Cell Aging in One Organ Can Snowball Into Multi-Organ Failure

Nov. 13, 2024 — The aging and failure of cells that occurs when one part of the body is damaged can spread to other organs, a study ...

Mouse Model Reveals Liver Involvement in Muscular Dystrophy

Oct. 24, 2024 — A new mouse model mimicking the liver symptoms of myotonic dystrophy type 1 -- the most prevalent form of adult-onset muscular dystrophy -- provides insight into why patients develop fatty liver ...

A Novel Approach to Combat Fatty Liver Disease

Oct. 9, 2024 — Blocking the enzyme ACMSD can significantly reduce damage caused by metabolic liver disease according to a new ...

Balancing Health: Diabetes and Obesity Increase Risk of Liver Cancer Relapse

Oct. 3, 2024 — A research team analyzed how diabetes mellitus and obesity factor into recurrence and survival after surgery for hepatocellular carcinoma, a type of liver ...

Researchers Identify Potential New Strategy to Slow the Development of Liver Fibrosis

Sep. 17, 2024 — A study reveals advances in the understanding and treatment of liver fibrosis, a serious complication in the context of metabolic fatty liver disease, also known as MASLD (metabolic ...

Finding New Targets for Blocking Chronic Hepatitis

Aug. 29, 2024 — Researchers revealed how certain liver cells contribute to inflammatory responses underlying chronic hepatitis. Using mouse and cell culture models, they observed increased levels of inflammatory ...

Macrophage Mix Helps Determine Rate and Fate of Fatty Liver Disease

Aug. 22, 2024 — The white blood cells' typical role is to promote inflammation and stimulate the immune response, but researchers say some actually appear to temper inflammatory conditions and improve ...

Hepatic Disease: A Camu-Camu Fruit Extract to Reduce Liver Fat

Aug. 21, 2024 — A research team has shown the benefits of camu-camu on non-alcoholic fatty liver disease. This exotic fruit reduces liver fat ...

Liver Transplant Outperforms Other Therapies for Colorectal Cancer That Has Spread to the Liver

July 30, 2024 — A study followed patients whose colorectal cancer was under control, but who had liver tumors that could not be surgically removed. All patients were eligible for liver transplantation, but some ...