Leukemia News

April 16, 2025

Top Headlines

Rapid Growth of Blood Cancer Driven by a Single Genetic 'Hit'

Apr. 9, 2025 — Researchers have explored the evolution of the genetic change that causes chronic myeloid leukaemia and show its ability to drive the ...

Driving the CAR to Fight Acute Myeloid Leukemia

Apr. 11, 2025 — A multi-institutional team developed a chimeric antigen receptor (CAR) T cell-based strategy for specifically targeting AML cells in patients who relapsed following other treatments. The team identified a monoclonal antibody called KG2032 that ...

Drug-Delivering Aptamers Target Leukemia Stem Cells for One-Two Knockout Punch

Apr. 3, 2025 — Drug-carrying DNA aptamers can deliver a one-two punch to leukemia by precisely targeting the elusive cancer stem cells that seed cancer relapses, researchers report. The aptamers -- short ...

New CAR-T Cell Therapy Shows Promise for Hard-to-Treat Cancers

Mar. 10, 2025 — Researchers have successfully developed a supercharged iteration of CAR-T cell therapy that can enhance the effectiveness and longevity of the cells, particularly against cancer cells that are harder for prior CAR-T therapies to detect and ...

Latest Headlines

updated 10:49pm EDT

How Our Lungs Back Up the Bone Marrow to Make Our Blood

Feb. 27, 2025 — Red blood cells carry oxygen from the lungs to every other organ, and blood-forming stem cells must make about 200 billion new red blood cells each day to keep the oxygen flowing. For many years, ...

New Combination Treatment Strategy Dramatically Increases Cell Death in Leukemia

Feb. 27, 2025 — Scientists have identified an innovative combination of treatment strategies that work collaboratively to effectively kill acute myeloid leukemia ...

Novel Bone Marrow Transplant Can Cure Sickle Cell Disease, Study Suggests

Feb. 25, 2025 — A bone marrow transplant process is safe and curative for adults with sickle cell disease, according to results of a trial completed at about 20 cancer ...

When Blood Cancer Starts to Spread

Feb. 10, 2025 — When blood cancer cells break through the bone and multiply, tumor cells become dangerously diverse and the immune response in the region changes, researchers report. The detailed insights into ...

Gene Modification Could Improve Cancer Treatment's Success Rate

Feb. 7, 2025 — A research team has made a major discovery on how the CUL5 gene affects CAR-T cell therapy, an advanced cancer therapy. The study reveals that reducing the activity of the CUL5 gene helps CAR-T cells ...

Study Unveils Key Immune Cells Found to Boost Cancer Treatment Success in Acute Myeloid Leukemia

Jan. 24, 2025 — A research team made a pivotal discovery in the field of cancer immunotherapy. The team identified a specific population of immune cells that play a ...

PET Probe Images Inflammation With High Sensitivity and Selectivity

Jan. 22, 2025 — Researchers have developed a breakthrough method to detect inflammation in the body using positron emission tomography (PET) imaging. This innovative probe targets CD45, a marker abundantly expressed ...

Drug in Clinical Trials for Breast Cancer Could Also Treat Some Blood Cancers

Jan. 16, 2025 — Two new studies have identified a possible way to block the progression of several forms of blood cancer using a drug already in clinical trials ...

New Innovative Local Treatment for Osteolytic Bone Disease in Multiple Myeloma

Jan. 14, 2025 — A team of researchers has developed a new biomaterial with high potential in in the treatment of bone lesions or minimal residual disease in multiple ...

Blood Test Could Make Cancer Treatments Safer and More Effective

Dec. 16, 2024 — Scientists have developed a new blood test that could screen cancer patients to help make their treatment safer and more ...

New Drug Tested to Reduce Side Effect of 'Half-Matched' Stem Cell Transplants

Dec. 5, 2024 — Stem cell transplantation is used to treat several types of blood cancers, but carries the risk of a life-threatening side effect called graft-versus-host disease. Results from a clinical trial ...

Changes in Blood Cell Production Over the Lifetime Could Impact Leukemia Outcomes

Dec. 5, 2024 — The first comprehensive map of the dramatic changes that take place in the blood system over the course of the human lifetime could have implications for the treatment of acute myeloid leukemia and ...

How Breast Cancer Cells Survive in Bone Marrow After Remission

Dec. 4, 2024 — A new study has shed light on a previously poorly understood aspect of breast cancer recurrence: how cancer cells survive in bone marrow despite targeted ...

The Most Extensive Epigenetic Database of Malignant Blood Cells Created

Nov. 26, 2024 — Researchers published a dataset covering thousands of methylated sites from hundreds of cancer-derived cultured cells, covering many leukemias, lymphomas and myelomas, from humans and mice. With this ...

Chromosomal Chaos Promotes Therapy Resistance in Leukemia Cells and Opens Up New Treatment Approaches

Nov. 25, 2024 — Chromosomal instability plays a crucial role in the progression of cancer: it shapes the properties of tumor cells and drives the development of therapy resistance. Scientists used state-of-the-art ...

Groundbreaking Research Unlocks Precision Therapy for Drug-Resistant Leukaemia

Nov. 8, 2024 — Scientists investigated how an inherited genetic variation common among East Asians contributes to drug resistance in cancer cells, driving more aggressive cancer growth. The team trialled a ...

Cellular Couriers: Body's 'Delivery Trucks' Could Lead to New Cancer Blood Test

Oct. 28, 2024 — Researchers have found a potential new diagnostic marker that could be used to better detect the level of tissue damage in our ...

Why Breast Cancer Spreads to Bone

Oct. 18, 2024 — Researchers have developed an in vitro cancer model to investigate why breast cancer spreads to bone. Their findings hold promise for advancing the development of preclinical tools to predict breast ...

Rapid Blood Cancer Diagnostic Could Speed Decisions and Save Lives

Oct. 9, 2024 — Researchers have created a CRISPR-based rapid molecular diagnostic for two forms of leukemia that are driven by mutations that involve gene fusions. The technology accurately detects the presence of ...

Promising Cell Therapy Offers Hope for Relapsed or Refractory T-Cell Leukaemia

Oct. 7, 2024 — Fratricide-resistant CD7 CAR-T therapy by NUS proves effective in treating relapsed or refractory T-cell ...

Radon, Even at Levels Below EPA Guideline for Mitigation, Is Linked to Childhood Leukemia

Sep. 30, 2024 — A study of more than 700 counties across multiple U.S. states found a link between childhood leukemia and levels of decaying radon gas, including those lower than the federal guideline for ...

Why Children With Down Syndrome Have Higher Risk of Leukemia

Sep. 26, 2024 — People with Down syndrome face a higher risk of developing leukemia. Now researchers explain why, by identifying specific changes in blood cells of people with Down ...

Triplet Regimen Yields Promising Response in Advanced-Phase Chronic Myeloid Leukemia

Sep. 17, 2024 — According to new research, 80% of patients with previously untreated or relapsed/refractory advanced-phase chronic myeloid leukemia (CML) -- including both accelerated or myeloid blast phases of the ...

Tumor-Induced B Cell Changes Reveal Potential Biomarker for Treatment Response in Triple Negative Breast Cancer

Sep. 12, 2024 — Researchers have discovered new insights into tumor-induced B cell changes in blood and bone marrow of triple negative breast cancer patients. The findings show two distinct patterns of B cell ...

Blood Stem Cell Breakthrough Could Transform Bone Marrow Transplants

Sep. 3, 2024 — Researchers have made a world first breakthrough into creating blood stem cells that closely resemble those in the human body. And the discovery could soon lead to personalized treatments for ...

P-Bodies Sustain Acute Myeloid Leukemia

Aug. 21, 2024 — An international team of scientists has uncovered a mechanism by which acute myeloid leukemia (AML) cells sustain their growth. AML cells prevent the synthesis of proteins that suppress their growth ...

Scientists Identify Genes Linked to Relapse in the Most Common Form of Childhood Leukemia

Aug. 12, 2024 — Scientists have identified novel genetic variations that influence relapse risk in children with standard risk B-cell acute lymphoblastic leukemia (SR B-ALL), the most common childhood ...

Potential New Approach to Enhancing Stem-Cell Transplants

Aug. 9, 2024 — A discovery may boost the effectiveness of stem-cell transplants, commonly used for patients with cancer, blood disorders, or autoimmune diseases caused by defective stem cells, which produce all the ...

Improved Chemokine Homing Enhances CAR T--Cell Therapy for Osteosarcoma

Aug. 5, 2024 — Investigators identified a chemokine/chemokine receptor mismatch for osteosarcoma (i.e., osteosarcomas secrete chemokines for which CAR T cells do not express receptors). The researchers modified CAR ...

Surprising Finding in Glioblastomas

July 31, 2024 — Glioblastomas are highly aggressive, usually incurable brain tumors. If all therapeutic options are exhausted, patients have an average life expectancy of less than two years. Now researchers have ...