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Parkinson's Research News

September 1, 2026

Top Headlines

 

Scientists have identified a protein that acts like a brake on the nervous system’s ability to repair damaged connections. Blocking AHR helped injured nerve fibers regrow and improved movement and sensation in mice with nerve or spinal cord ...
Scientists have created light-activated drugs that helped blind mice perceive light again and restored visually guided behavior without gene therapy, implants, or specialized lighting. Even more intriguingly, two of the most promising compounds ...
Early-life stress may physically alter how DNA is packaged in the brain, leaving stress-related genes primed to activate more easily years later. In mice, researchers were able to block this effect, preventing the heightened anxiety and stress ...
A major study found that adults with depression show disrupted production of new neurons in the hippocampus, potentially weakening the brain’s ability to separate new experiences from painful memories. The researchers also identified broad ...
Researchers have uncovered a possible reason why the Alzheimer’s risk gene APOE4 can disrupt the brain long before memory problems begin. In mice, APOE4 increased a protein called Nell2, shrinking ...
The longevity-linked APOE2 gene appears to protect brain cells by reducing DNA damage and helping neurons recover from stress. The finding could open a new path toward treatments that mimic APOE2’s defenses in people at higher genetic risk for ...
An existing constipation drug may have an unexpected new use: helping clear the "brain fog" that often lingers after depression. In a small clinical trial, people with a history of depression who took the medication prucalopride for about a week ...
Researchers have discovered that a microscopic skeleton inside neurons does much more than hold cells together. It acts as a gatekeeper that controls what brain cells absorb and when they absorb it. ...
Yale scientists discovered two neuron surface proteins that appear to help spread the toxic protein linked to Parkinson’s disease. Blocking these proteins in mice dramatically reduced disease ...
A surprising discovery is overturning a long-held assumption about how the brain’s movement center works. Researchers found that two key cerebellar cell types—thought to be tightly linked—often ...
Creatine is best known as a muscle-building supplement, but scientists are now investigating whether it could also help treat depression by boosting the brain's energy supply. A new review examined five randomized clinical trials involving 238 ...
Scientists at UCLA have linked long-term exposure to the pesticide chlorpyrifos with a sharply increased risk of Parkinson’s disease. People exposed to the chemical near their homes were more than ...

Latest Headlines

updated 9:18am EDT

Earlier Headlines

 

Researchers have discovered a surprising change in how cells produce energy in people with depression. Brain and blood cells in young adults with major depressive disorder produced more energy ...

Aging men often lose the Y chromosome in a growing number of their cells—and it may be far more dangerous than once believed. This loss has been linked to heart disease, cancer, Alzheimer’s, and ...

A sweeping review of global research suggests that exercise—especially aerobic activities like running, swimming, and dancing—can be one of the most powerful ways to ease depression and anxiety. ...

Human evolution has long been tied to growing brain size, and new research suggests prenatal hormones may have played a surprising role. By studying the relative lengths of index and ring fingers — ...

A new study suggests a widely used bone hormone could help relieve chronic back pain in an unexpected way. Instead of just strengthening bone, it appears to stop pain-sensing nerves from growing into ...

A new international study points to a specific brain network as the core driver of Parkinson’s disease. Scientists found that this network becomes overly connected, disrupting not just movement but ...

Scientists in Sweden and Norway have uncovered a promising way to spot Parkinson’s disease years—possibly decades—before its most damaging symptoms appear. By detecting subtle biological ...

A massive international study of more than 3,100 long COVID patients uncovered a striking divide in how brain-related symptoms are reported around the world. In the U.S., the vast majority of ...

Depression in older adults may sometimes signal the early stages of Parkinson’s disease or Lewy body dementia. Researchers found that depression often appears years before diagnosis and remains ...

Researchers report that vagus nerve stimulation helped many people with long-standing, treatment-resistant depression feel better—and stay better—for at least two years. Most participants had ...

A new UCLA Health study suggests that long-term exposure to the pesticide chlorpyrifos may dramatically raise the risk of Parkinson’s disease. Researchers found that people living in areas with ...

Scientists at USC are launching a new trial to test a tiny stem cell implant that could restore vision in people with advanced dry macular degeneration. The hair-thin patch replaces damaged retinal ...

A massive global genetics study is reshaping how we understand mental illness—and why diagnoses so often pile up. By analyzing genetic data from more than six million people, researchers uncovered ...

Nitrous oxide may offer quick, short-term relief for people with major depression, especially those who haven’t responded to standard medications. The meta-analysis found rapid improvements after a ...

A large Mayo Clinic study shows that current guidelines fail to detect nearly 90% of people with familial hypercholesterolemia, a common inherited cause of dangerously high cholesterol. Many affected ...

Researchers uncovered how estrogen subtly reshapes learning by strengthening dopamine reward signals in the brain. Rats learned faster when estrogen levels were high and struggled when the ...

Duke-NUS scientists unveiled BrainSTEM, a revolutionary single-cell map that captures the full cellular diversity of the developing human brain. The project’s focus on dopamine neurons provides ...

Sertraline (Zoloft) may relieve emotional symptoms of depression and anxiety within two weeks, while physical side effects stabilize later. The research highlights how antidepressants can act on ...

Researchers compared a traditional Chinese medicine, Yueju Pill, with a standard antidepressant and found both reduced depression symptoms. However, only Yueju Pill increased a brain-supporting ...

Researchers identified SGK1 as a key chemical connecting childhood trauma to depression and suicidal behavior. High SGK1 levels were found in the brains of suicide victims and in people with genetic ...

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