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Crohn's Disease News

March 23, 2026

Top Headlines

 

A risky but often lifesaving surgery that removes damaged parts of the small intestine can leave patients facing a new threat: serious liver damage with no available treatment. Now, scientists have ...
Early life stress may set the stage for long-term digestive problems by disrupting the gut-brain connection. Studies in both mice and thousands of children found links to symptoms like pain, constipation, and IBS. Scientists discovered that ...
A new UCLA Health study suggests that long-term exposure to the pesticide chlorpyrifos may dramatically raise the risk of Parkinson’s disease. Researchers found that people living in areas with sustained exposure had more than 2.5 times the ...
Scientists at MIT have discovered that a little-known protein called intelectin-2 plays a powerful double role in defending the gut. The protein strengthens the mucus layer that lines the gastrointestinal tract while also trapping and disabling ...
Researchers have identified two gut bacteria that can produce serotonin, a key chemical that regulates bowel movements. In experiments with mice lacking serotonin, the microbes boosted serotonin levels, increased nerve cells in the colon, and ...
Researchers studying over 8,400 colonoscopies discovered that having both adenomas and serrated polyps in the bowel can raise the risk of serious precancerous changes by up to five times. These two polyp types may represent separate cancer pathways ...
Daily aspirin does not reliably prevent bowel cancer in people at average risk, according to a major new review. Any potential protective effect may take more than a decade to appear — if it ...
A new human study has uncovered how the body naturally turns off inflammation. Researchers found that fat-derived molecules called epoxy-oxylipins rein in immune cells that can otherwise drive chronic disease. Using a drug to boost these molecules ...
A global study has uncovered a mysterious group of gut bacteria that shows up again and again in healthy people. Known as CAG-170, these microbes were found at lower levels in people with a range of chronic diseases. Genetic clues suggest they help ...
A new clinical trial suggests that changing when you eat could make a meaningful difference for people living with Crohn’s disease. Researchers found that time-restricted feeding, a form of intermittent fasting that limits meals to an 8-hour daily ...
A newly uncovered immune chain reaction in the gut may explain why people with inflammatory bowel disease face a much higher risk of colorectal cancer. Researchers found that a powerful inflammatory signal flips on specialized gut immune cells, ...
Chronic inflammation may be quietly reshaping the colon and making it more vulnerable to early-onset colorectal cancer. Scientists found that colon tissue in younger patients was stiffer, even in areas that appeared healthy, suggesting these changes ...

Latest Headlines

updated 5:53am EDT

Earlier Headlines

 

Spermine, a small but powerful molecule in the body, helps neutralize harmful protein accumulations linked to Alzheimer’s and Parkinson’s. It encourages these misfolded proteins to gather into ...

Researchers discovered that chemotherapy can accidentally trigger a stress alarm in immune cells, causing inflammation that damages nerves. Blocking this alarm protected mice from nerve pain and kept ...

Tiny ingestible spheres filled with engineered bacteria can detect intestinal bleeding by glowing when they encounter heme. Early tests in mice suggest they could become a quick, noninvasive way to ...

Researchers discovered that chronic inflammation fundamentally remodels the bone marrow, allowing mutated stem cell clones to quietly gain dominance with age. Reprogrammed stromal cells and ...

Scientists are uncovering how GLP-1 drugs like Ozempic and Wegovy act on brain regions that control hunger, nausea, pleasure-based eating, and thirst. These discoveries may help create treatments ...

Chronic pain might quietly push people toward developing high blood pressure—and the more widespread the pain, the greater the danger. A massive analysis of over 200,000 adults uncovered strong ...

Scientists have pinpointed a “Big Bang” moment in bowel cancer—when cells first evade the immune system. This early immune escape locks in how the cancer will behave as it grows. The discovery ...

UC San Diego researchers combined artificial intelligence with molecular biology to unravel how immune cells in the gut decide between inflammation and healing, a process gone awry in Crohn’s ...

Endurance exercise may train the immune system as much as the muscles. Older adults with decades of running or cycling had immune cells that functioned better and aged more slowly. Their inflammation ...

Researchers discovered that altering the body’s natural rhythm can help protect the brain from Alzheimer’s damage. By turning off a circadian protein in mice, they raised NAD+ levels and reduced ...

MIT scientists have found that an amino acid called cysteine can help the gut heal itself. In mouse studies, a cysteine-rich diet activated immune cells that release a molecule speeding up tissue ...

Researchers have designed a peptide that prevents the deadly misfolding of alpha-synuclein, the protein behind Parkinson’s and some dementias. In lab and animal tests, it stabilized the protein and ...

Scientists have discovered a way to block pain while still allowing the body’s natural healing to take place. Current painkillers like ibuprofen and aspirin often come with harmful side effects ...

Morning sickness isn’t just random misery—it’s a biological defense system shaped by evolution to protect the fetus. By linking immune responses to nausea and food aversions, UCLA researchers ...

Duke University scientists have discovered that pancreatic alpha cells, long believed to only produce glucagon, actually generate powerful amounts of GLP-1 — the same hormone mimicked by popular ...

Daily cocoa extract supplements reduced key inflammation markers in older adults, pointing to a role in protecting the heart. The findings reinforce the value of flavanol-rich, plant-based foods for ...

For decades, scientists have puzzled over why smoking makes Crohn’s disease worse but seems to protect people from ulcerative colitis. Now, researchers at RIKEN have discovered that smoking creates ...

Researchers found that pancreatic pre-cancer cells mimic dementia by forming clumps of proteins due to faulty recycling processes. These insights could shed light on why pancreatic cancer develops so ...

Japanese scientists have developed ADRIANA, a non-opioid painkiller that could provide powerful relief without the dangers of addiction. With successful trials already completed, large U.S. studies ...

A new global study reveals a striking post-pandemic surge in gut-brain disorders like IBS and functional dyspepsia. Researchers compared data from 2017 and 2023 and discovered sharp increases IBS up ...

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