Alzheimer's Research News

January 21, 2025

Top Headlines

New Study Uncovers Key Mechanism Behind Learning and Memory

Jan. 21, 2025 — A breakthrough study sheds new light on how brain cells relay critical information from their extremities to their nucleus, leading to the activation of genes essential for learning and ...

Antibiotics, Vaccinations and Anti-Inflammatory Medication Linked to Reduced Risk of Dementia

Jan. 21, 2025 — Antibiotics, antivirals, vaccinations and anti-inflammatory medication are associated with reduced risk of dementia, according to new research that looked at health data from over 130 million ...

Brain Immune Cells May Also Be from 'Mars and Venus'

Jan. 21, 2025 — Researchers find that microglia function differently in males versus females, potentially having broad implications for how neurological diseases are ...

Brain Changes in Huntington's Disease Decades Before Diagnosis Will Guide Future Prevention Trials

Jan. 17, 2025 — Subtle changes in the brain, detectable through advanced imaging, blood and spinal fluid analysis, happen approximately twenty years before a clinical motor diagnosis in people with Huntington's ...

Latest Headlines

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Florescent Probes Illuminate Cholesterol and Alzheimer's Research

Jan. 17, 2025 — Cutting-edge fluorescent cholesterol probes now enable scientists to visualize cholesterol movement and distribution in live cells with unprecedented detail. By combining computer simulations with ...

Aerobic Exercise: A Powerful Ally in Fight Against Alzheimer's

Jan. 15, 2025 — Regular aerobic exercise could significantly reduce disease markers associated with Alzheimer's, new research has found. The findings provide new hope in the battle against this devastating ...

Xenon Gas Could Protect Against Alzheimer's Disease: Mouse Study

Jan. 15, 2025 — Most treatments being pursued today to protect against Alzheimer's disease focus on amyloid plaques and tau tangles that accumulate in the brain, but new research points to a novel -- and noble -- ...

A Molecule Is Shown to Produce Cognitive Improvement in Rodents With Early Alzheimer's Disease

Jan. 15, 2025 — Scientists have come up with a drug that is a potential candidate for tackling memory deficits in the early stages of the disease in rodents. ...

Circulation Problems in the Brain's Seat of Memory Linked to Mild Cognitive Impairment in Older Adults

Jan. 13, 2025 — Mild cognitive impairment is linked to blood vessel dysfunction in the brain's temporal lobes -- the seat of memory -- according to a new study. The ...

United States Dementia Cases Estimated to Double by 2060

Jan. 13, 2025 — A new study shows that the risk of developing dementia anytime after age 55 among Americans is 42%, more than double the risk reported by older ...

Brain Connectome Phenotype Linked to Cerebrovascular Disease Can Track Cognitive Decline

Jan. 13, 2025 — Researchers have uncovered novel insights into how brain function disruptions related to cerebrovascular disease (CeVD) interact with Alzheimer's ...

Dementia With Lewy Bodies Has Been Difficult to Diagnose Early, but Comprehensive Cognitive Testing Could Change That

Jan. 10, 2025 — Cognitive profiles for early diagnosis of Dementia with Lewy bodies (DLB) have been outlined in a new study. Although DLB is the second most common ...

What Is the Average Wait Time to See a Neurologist in US?

Jan. 8, 2025 — Older people wait an average of just over a month to see a neurologist for specialty care after being referred by their primary care physician or another physician, according to a new study. The ...

Study Advances Possible Blood Test for Early-Stage Alzheimer's Disease

Jan. 8, 2025 — Declining blood levels of two molecules that occur naturally in the body track closely with worsening Alzheimer's disease, particularly in women. Levels were found to drop gradually, from women with ...

How Deep Sleep Clears a Mouse's Mind, Literally

Jan. 8, 2025 — A good night's sleep does more than just help you feel rested--it might literally clear your mind. A new study shows how deep sleep may wash away waste buildup in the brain during waking hours, ...

Potential New Therapeutic Targets for Huntington's Disease

Jan. 8, 2025 — A research team has discovered intricate molecular mechanisms driving the RNA processing defects that lead to Huntington's disease and link HD with other neurodegenerative disorders such as ...

How Our Cells Dispose of Waste and Ways to Control It

Jan. 7, 2025 — Cells degrade components that are no longer needed through autophagy. New results show that a weak molecular interaction is essential for this process. By modifying this interaction, it is possible ...

Study Challenges Traditional Risk Factors for Brain Health in the Oldest-Old

Jan. 7, 2025 — A study has found cardiovascular conditions such as high blood pressure and diabetes, which are known to contribute to brain blood vessel damage in younger populations, not to be associated with an ...

Study Shows Head Trauma May Activate Latent Viruses, Leading to Neurodegeneration

Jan. 7, 2025 — Researchers have uncovered mechanisms that may link head injuries and concussions to the emergence of neurodegenerative disease, pointing to latent viruses lurking in most of our brains that may be ...

Neurodegenerative Diseases: Membrane Anchor Suppresses Protein Aggregation

Jan. 6, 2025 — Protein aggregation is typical of various neurodegenerative diseases such as Alzheimer's, Parkinson's and prion diseases such as Creutzfeld-Jakob disease. A research team has now used new ...

Herpes Virus Might Drive Alzheimer's Pathology

Jan. 2, 2025 — Viral infections may play a role in Alzheimer's ...

Gene Editing Tool Reduces Alzheimer's Plaque Precursor in Mice

Dec. 23, 2024 — A new gene editing tool that helps cellular machinery skip parts of genes responsible for diseases has been applied to reduce the formation of amyloid-beta plaque precursors in a mouse model of ...

New Research Identifies Key Cellular Mechanism Driving Alzheimer's Disease

Dec. 23, 2024 — Researchers have unveiled a critical mechanism that links cellular stress in the brain to the progression of Alzheimer's disease (AD). The study highlights microglia, the brain's primary ...

Poor Vascular Health Accelerates Brain Aging

Dec. 20, 2024 — Using an AI tool, researchers have analyzed brain images from 70-year-olds and estimated their brains' biological age. They found that factors detrimental to vascular health, such as ...

Brain Inflammation Alters Behavior According to Sex, Mouse Study Finds

Dec. 19, 2024 — Inflammation in the hippocampus -- the brain's memory center -- significantly alters motivation and behavior in mice, according to new ...

The Surprising Role of Gut Infection in Alzheimer's Disease

Dec. 19, 2024 — Researchers have discovered a surprising link between a chronic gut infection caused by a common virus and the development of Alzheimer's disease in a subset of people. It is believed most ...

First Successful Clinical Trial of VU319 Brings Alzheimer's Treatment One Step Closer

Dec. 19, 2024 — Phase I clinical trial of a drug was successfully completed, with promise to treat Alzheimer's and other neurodegenerative diseases. The compound, named VU319, is the first end-to-end drug ...

Study Finds Antibiotics Not Linked to Dementia

Dec. 18, 2024 — For healthy older adults, using antibiotics is not associated with an increased risk of cognitive impairment or dementia, according to a new ...

Study Supports New Blood-Based Biomarker to Detect Early Brain Changes Leading to Cognitive Impairment and Dementia

Dec. 18, 2024 — To identify and follow blood vessel-related changes in the brain that contribute to cognitive impairment and dementia, researchers and clinicians typically rely on MRI to evaluate ...

Peptide-Guided Nanoparticles Deliver mRNA to Neurons

Dec. 17, 2024 — Engineers have modified lipid nanoparticles (LNPs) -- the revolutionary technology behind the COVID-19 mRNA vaccines -- to not only cross the blood-brain barrier (BBB) but also to target specific ...

Study Finds Lower Rates of Death from Alzheimer's Disease Among Taxi and Ambulance Drivers

Dec. 16, 2024 — A new study raises the possibility that jobs that require frequent spatial processing -- such as figuring out a taxi route or the best way to navigate to a hospital -- could lead to lower rates of ...

Common Brain Network Links Brain Atrophy Patterns Seen in Schizophrenia

Dec. 12, 2024 — A new study has identified a unique brain network that links varied patterns of brain atrophy, or shrinkage, associated with ...

Fluctuating Blood Pressure Tied to Problems With Thinking Skills

Dec. 11, 2024 — Older adults whose blood pressure fluctuates over time may be more likely to have problems with thinking and memory skills, according to a new study. The association was found in Black participants ...

Study Helps Solve Mystery Between Repeated Head Impacts in Sports and Location of Brain Degeneration in CTE

Dec. 9, 2024 — A new study is helping solve the mystery as to why the brain shrinks in a unique pattern, known as atrophy, in chronic traumatic encephalopathy (CTE). This research provides novel evidence that ...