CRISPR Gene Editing News

December 22, 2024

Top Headlines

Activating the Hidden Pharmaceutical Potential of Bacteria

Dec. 13, 2024 — Microorganisms produce a wide variety of natural products that can be used as active ingredients to treat diseases such as infections or cancer. The blueprints for these molecules can be found in the microbes' genes, but often remain inactive under ...

CRISPR-Cas Technology: Balancing Efficiency and Safety

Dec. 4, 2024 — Researchers have uncovered a serious side effect of using the CRISPR-Cas gene scissors. A molecule designed to make the process more efficient destroys parts of the ...

New Gene Drive Reverses Insecticide Resistance in Pests... Then Disappears

Nov. 22, 2024 — Geneticists have developed a gene drive-based solution to the widespread problem of insecticide resistance. In an effort to protect valuable crops, the researchers created an 'e-Drive' that reverses insecticide resistance and then disappears from ...

Labeling Cell Particles With Barcodes

Nov. 19, 2024 — Cell-to-cell communication through nanosized particles, working as messengers and carriers, can now be analyzed in a whole new way, thanks to a new method involving CRISPR gene-editing technology. The particles, known as small extracellular vesicles ...

Latest Headlines

updated 11:16pm EST

Using CRISPR to Decipher Whether Gene Variants Lead to Cancer

Nov. 12, 2024 — Researchers have combined two gene editing methods. This enables them to quickly investigate the significance of many genetic mutations involved in the development and treatment of ...

Finding Function for Noncoding RNAs Using a New Kind of CRISPR

Nov. 7, 2024 — Genes contain instructions for making proteins, and a central dogma of biology is that this information flows from DNA to RNA to proteins. But only two percent of the human genome actually encodes ...

Use of 'Genetic Scissors' Carries Risks

Nov. 6, 2024 — The CRISPR tool is capable of repairing the genetic defect responsible for the immune disease chronic granulomatous disease. However, researchers have now shown that there is a risk of inadvertently ...

Researchers Discover Underlying Mechanisms That Make CRISPR an Effective Gene Editing Tool

Oct. 28, 2024 — Using state-of-the-art technology, researchers have identified several specific steps needed for CRISPR to become active and perform its gene editing ...

Structure of a Eukaryotic CRISPR-Cas Homolog, Fanzor2, Shows Its Promise for Gene Editing

Oct. 1, 2024 — Scientists have revealed how Fanzor2's divergence from bacterial ancestors may make it a useful tool for future genomic engineering ...

Compact 'Gene Scissor' Enables Effective Genome Editing

Sep. 23, 2024 — CRISPR-Cas is used broadly in research and medicine to edit, insert, delete or regulate genes in organisms. TnpB is an ancestor of this well-known 'gene scissor' but is much smaller and thus easier ...

CREME AI and CRISPR in Tandem

Sep. 16, 2024 — CREME is a virtual laboratory that allows scientists to simulate specific decreases in gene activity. It offers a powerful new tool for identifying and understanding important parts of the genome. ...

Beyond Needles: Introducing a New, Nature-Based Approach for Delivering Cargo Into Egg Cells

Sep. 11, 2024 — A new approach for delivering miniature research tools into the interior of egg cells and embryos has been developed, resolving a major bottleneck to ...

CRISPR/Cas9 Modifies Euglena to Create Potential Biofuel Source

Sep. 13, 2024 — Through genome editing using CRISPR/Cas9, researchers stably create euglena mutants that can produce wax esters with improved cold flow, making the esters suitable as feedstock for ...

Genomic Dark Matter Solves Butterfly Evolutionary Riddle

Aug. 30, 2024 — Researchers have uncovered a surprising genetic mechanism that influences the vibrant and complex patterns on butterfly wings. The team discovered that an RNA molecule, rather than a protein as ...

Immune System That Bacteria Use to Respond to Viral Infections

Aug. 26, 2024 — An article highlights new insights into the PARIS, an immune system that bacteria use to respond to viral ...

Bacteria Encode Hidden Genes Outside Their Genome--Do We?

Aug. 9, 2024 — A 'loopy' discovery in bacteria is raising fundamental questions about the makeup of our own genome -- and revealing a potential wellspring of material for new genetic ...

Precise Genetics: New CRISPR Method Enables Efficient DNA Modification

July 30, 2024 — A research group has developed a new method that further improves the existing CRISPR/Cas technologies: it allows a more precise and seamless introduction of tags into proteins at the gene level. ...

A New Addition to the CRISPR Toolbox: Teaching the Gene Scissors to Detect RNA

July 16, 2024 — CRISPR-Cas systems, defense systems in bacteria, have become a plentiful source of technologies for molecular diagnostics. Researchers have now expanded this extensive toolbox further. Their novel ...

Big Gain in Battle Against Harmful Bacteria

July 10, 2024 — An unexpected find has enabled important progress to be made in the battle against harmful ...

New Tool Enables Faster, More Cost-Effective Genome Editing of Traits to Improve Agriculture Sustainability

June 26, 2024 — New research had the goal of reducing the time and cost it takes to bring an improved crop to the marketplace to improve agriculture ...

Modifying Genomes of Tardigrades to Unravel Their Secrets

June 13, 2024 — Some species of tardigrades are highly and unusually resilient to various extreme conditions fatal to most other forms of life. The genetic basis for these exceptional abilities remains elusive. ...

Scientists Engineer Yellow-Seeded Camelina With High Oil Output

June 11, 2024 — Using tools of modern genetics, plant biochemists have produced a new high-yielding oilseed crop variety -- a yellow-seeded variety of Camelina sativa, a close relative of canola, that accumulates ...

Fine-Tuning Leaf Angle With CRISPR Improves Sugarcane Yield

June 10, 2024 — A CABBI research team has used CRISPR/Cas9 gene editing to optimize leaf angle in sugarcane, increasing the amount of sunlight it captures and the amount of biomass it ...

Changes Upstream: RIPE Team Uses CRISPR/Cas9 to Alter Photosynthesis for the First Time

June 7, 2024 — Scientists used CRISPR/Cas9 to increase gene expression in rice by changing its upstream regulatory DNA. While other studies have used the technology to knock out or decrease the expression of genes, ...

New, Modified CRISPR Protein Can Fit Inside Virus Used for Gene Therapy

May 30, 2024 — Researchers have developed a novel version of a key CRISPR gene-editing protein that shows efficient editing activity and is small enough to be packaged within a non-pathogenic virus that can deliver ...

Editing Without 'Cutting': Molecular Mechanisms of New Gene-Editing Tool Revealed

May 29, 2024 — New research has determined the spatial structure of various processes of a novel gene-editing tool called 'prime editor.' Functional analysis based on these structures also revealed how a ...

Research on RNA Editing Illuminates Possible Lifesaving Treatments for Genetic Diseases

Apr. 29, 2024 — The research explores how CRISPR can be used to edit ...

Innovative Antiviral Defense With New CRISPR Tool

Apr. 12, 2024 — The rise of RNA viruses like SARS-CoV-2 highlights the need for new ways to fight them. RNA-targeting tools like CRISPR/Cas13 are powerful but inefficient in the cytoplasm of cells, where many RNA ...

CRISPR-Copies: New Tool Accelerates and Optimizes Genome Editing

Feb. 13, 2024 — Researchers are further improving CRISPR's versatility to engineer new grasses and yeasts for biochemical ...

Bioinformatics: Researchers Develop a New Machine Learning Approach

Jan. 13, 2024 — To combat viruses, bacteria and other pathogens, synthetic biology offers new technological approaches whose performance is being validated in experiments. Researchers applied data integration and ...

Scientists Use Quantum Biology, AI to Sharpen Genome Editing Tool

Nov. 9, 2023 — Scientists used their expertise in quantum biology, artificial intelligence and bioengineering to improve how CRISPR Cas9 genome editing tools work on organisms like microbes that can be modified to ...

Researchers Develop DANGER Analysis Tool for the Safer Design of Gene Editing

Oct. 23, 2023 — A team of researchers has developed a software tool that provides a way for the safer design of genome editing in all organisms with a transcriptome. For about a decade, researchers have used the ...

You Say Genome Editing, I Say Natural Mutation

Oct. 19, 2023 — A plant geneticist and computational biologist teamed up to decipher the unpredictability of natural and engineered mutations in tomatoes. They discovered some combinations of mutations behave as ...

Scientists Uncover New Way Viruses Fight Back Against Bacteria

Oct. 18, 2023 — A microscopic discovery will not only enable scientists to understand the microbial world around us but could also provide a new way to control CRISPR-Cas ...