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Bone and Spine News

April 12, 2026

Top Headlines

 

Scientists have identified a little-known receptor, GPR133, as a powerful regulator of bone strength. By activating it with a newly discovered compound called AP503, they were able to boost bone density in mice and counteract osteoporosis-like ...
Scientists have created an artificial saliva using a sugarcane protein that can protect teeth and fight bacteria. The key ingredient, CANECPI-5, binds directly to enamel, forming a shield against ...
Scientists have developed a new gene therapy that quiets pain at its source in the brain—without the addictive risks of opioids. Using AI to map how pain is processed, they created a targeted “off switch” that mimics morphine’s benefits but ...
A new study suggests a widely used bone hormone could help relieve chronic back pain in an unexpected way. Instead of just strengthening bone, it appears to stop pain-sensing nerves from growing into damaged spinal areas. In animal models, this led ...
Early life stress may set the stage for long-term digestive problems by disrupting the gut-brain connection. Studies in both mice and thousands of children found links to symptoms like pain, constipation, and IBS. Scientists discovered that ...
A Yale study found that lowering parent stress can help protect young children from obesity. When parents practiced mindfulness and stress-management skills, their kids showed healthier eating ...
Stiff knees and aching hips may seem like an inevitable part of aging, but experts say we’re getting osteoarthritis all wrong. Despite affecting nearly 600 million people worldwide — and ...
When a bone break is too severe to heal on its own, surgeons often rely on grafts or rigid metal implants — but both come with serious drawbacks. Now, researchers at ETH Zurich have created a jelly-like hydrogel that mimics the body’s natural ...
A sweeping new analysis of the evidence suggests that exercise therapy — long promoted as a first-line treatment for osteoarthritis — may offer only small and short-lived relief, and in some cases might be no better than doing nothing at all. ...
Babies born in the early 2000s were exposed in the womb to far more “forever chemicals” than researchers once realized, according to a new study. By using advanced chemical screening on umbilical ...
Chronic wounds often spiral out of control because oxygen can’t reach the deepest layers of injured tissue. A new gel developed at UC Riverside delivers a continuous flow of oxygen right where it’s needed most, using a tiny battery-powered ...
A new human study has uncovered how the body naturally turns off inflammation. Researchers found that fat-derived molecules called epoxy-oxylipins rein in immune cells that can otherwise drive chronic disease. Using a drug to boost these molecules ...

Latest Headlines

updated 9:43am EDT

Earlier Headlines

 

As spinal cord injuries increasingly affect older adults, new research reveals a surprising pattern in recovery. The study shows that aging does not appear to slow the healing of nerves themselves, ...

Cannabis products with higher THC levels may slightly reduce chronic pain, particularly nerve pain, according to a review of multiple clinical trials. The improvement was small and short-lived, while ...

SereNeuro Therapeutics revealed promising results for SN101, a first-in-class iPSC-derived therapy designed to treat chronic osteoarthritis pain while protecting joint tissue. Instead of blocking ...

A decade-long study of older women found that tea drinkers had slightly stronger bones, while moderate coffee drinking caused no harm. Heavy coffee intake—over five cups a day—was linked to lower ...

Researchers used a deep learning AI model to uncover the first imaging-based biomarker of chronic stress by measuring adrenal gland volume on routine CT scans. This new metric, the Adrenal Volume ...

A research team has found that specific immune cells can connect with muscle fibers in a lightning-fast, neuron-like way to promote healing. These cells deliver quick pulses of calcium, triggering ...

Researchers discovered that chemotherapy can accidentally trigger a stress alarm in immune cells, causing inflammation that damages nerves. Blocking this alarm protected mice from nerve pain and kept ...

Researchers have uncovered a surprising way the brain switches pain on, revealing that neurons can release an enzyme outside the cell that activates pain signals without disrupting normal movement or ...

Chronic pain might quietly push people toward developing high blood pressure—and the more widespread the pain, the greater the danger. A massive analysis of over 200,000 adults uncovered strong ...

Researchers developed a new nano-micelle formulation, CBD-IN, that finally gets CBD into the brain effectively. In mice, it relieved neuropathic pain quickly and didn’t cause the usual movement or ...

Researchers have uncovered that SerpinB3, typically linked to severe cancers, is also a key player in natural wound healing. The protein drives skin cell movement and tissue rebuilding, especially ...

Researchers in Osaka have found that stem cells from fat tissue can repair spinal fractures similar to those caused by osteoporosis. By turning these cells into bone-forming clusters and pairing them ...

Boston researchers linked nighttime light exposure to greater stress-related brain activity and inflamed arteries, signaling a higher risk of heart disease. The study suggests that artificial light ...

Texas A&M researchers found that in an aggressive kidney cancer, RNA builds “droplet hubs” that activate tumor genes. By creating a molecular switch to dissolve these hubs, they stopped ...

A wireless eye implant developed at Stanford Medicine has restored reading ability to people with advanced macular degeneration. The PRIMA chip works with smart glasses to replace lost photoreceptors ...

A groundbreaking retinal implant called PRIMA has enabled blind patients with dry AMD to read again. The chip, powered by light and paired with AR glasses, sends visual data directly to the brain. In ...

Scientists have pinpointed Y1 receptor neurons in the brain that can override chronic pain signals when survival instincts like hunger or fear take precedence. Acting like a neural switchboard, these ...

Tramadol, a popular opioid often seen as a “safer” painkiller, may not live up to its reputation. A large analysis of clinical trials found that while it does reduce chronic pain, the relief is ...

A long-term Australian study found that calcium supplements do not raise dementia risk in older women, countering previous fears. The research followed more than 1,400 participants for nearly 15 ...

Penn researchers found that psilocybin can calm brain circuits tied to pain and mood, easing both physical suffering and emotional distress in animal studies. The compound works in the anterior ...

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