Mice News

May 3, 2025

Top Headlines

Once Bitten, Animals Develop Resistance That Shrinks Tick Population

Apr. 30, 2025 — Just in time for tick season, new research is shining a light on how animals develop resistance to tick bites, which points toward the possibility of developing more effective vaccines against the tiny, disease-carrying ...

New Technology Facilitates Delivery of Advanced Medicines

Apr. 30, 2025 — Researchers have developed a technique that enables efficient delivery of therapeutic proteins and RNA to cells. The method shows promising results in animal studies to deliver gene editors and protein ...

A Digestive 'Treasure Chest' Shows Promise for Targeted Drug Treatment in the Gut

May 1, 2025 — A new approach to drug design can deliver medicine directly to the gut in mice at significantly lower doses than current inflammatory bowel disease treatments. The proof-of-concept study introduced a ...

Antivenom Neutralizes the Neurotoxins of 19 of the World's Deadliest Snakes

May 2, 2025 — By using antibodies from a human donor with a self-induced hyper-immunity to snake venom, scientists have developed the most broadly effective antivenom to date, which is protective against the likes of the black mamba, king cobra, and tiger snakes ...

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New Mouse Brain Atlas Will Accelerate Studies of Neurological Disorders

Apr. 30, 2025 — A new 3D 'atlas' of the mouse brain promises to sharpen scientists' ability to measure brain changes and share findings across studies of diseases like Alzheimer's. The mouse brain atlas combines ...

Protein Sources Change the Gut Microbiome -- Some Drastically

Apr. 30, 2025 — Protein sources appear to have major effects on both the population and function of the mouse gut ...

Bacteria's Mysterious Viruses Can Fan Flames of Antibiotic Damage

Apr. 28, 2025 — Scientists built a model that allows them to diminish phage communities from a mouse gut microbiome -- and then bring them back -- without affecting the bacteria. On a test run of their model, ...

How Bacteria in Our Aging Guts Can Elevate Risk of Leukemia and Perhaps More

Apr. 23, 2025 — Scientists have discovered a surprising new connection between gut health and blood cancer risk one that could transform how we think about aging, ...

Blocking a Surprising Master Regulator of Immunity Eradicates Liver Tumors in Mice

Apr. 24, 2025 — 'Cold' tumors are resistant to common immunotherapies. Researchers have uncovered a master regulator that can be manipulated to prevent tumor growth ...

One Gene Defines the Many Patterns of Snake Skin

Apr. 24, 2025 — In many animals, skin coloration and its patterns play a crucial role in camouflage, communication, or thermoregulation. In the corn snake, some morphs display red, yellow, or pink blotches, and ...

Experimental Bird Flu Vaccine Excels in Animal Models

Apr. 17, 2025 — A vaccine under development has demonstrated complete protection in mice against a deadly variant of the virus that causes bird flu. The work focuses on the H5N1 variant known as 2.3.4.4b, which has ...

Researchers Use Machine Learning to Engineer 'Bespoke Enzymes' for Gene Editing

Apr. 22, 2025 — Genome editing has advanced at a rapid pace with promising results for treating genetic conditions -- but there is always room for improvement. A new ...

Obesity Disrupts 'Reaction Time' to Starvation in Mice

Apr. 22, 2025 — Researchers have revealed a temporal disruption in the metabolism of obese mice when adapting to starvation despite no significant structural disruptions in the molecular network. This is a ...

Experimental Cancer Drug Could Streamline Standard Tuberculosis Treatment and Prevent Post-TB Lung Disease, Study Suggests

Apr. 21, 2025 — An experimental drug now in clinical trials as a cancer treatment could help boost the power of first-line tuberculosis (TB) treatments by helping ...

Engineered Microglia Show Promise for Treating Alzheimer's and Other Brain Diseases

Apr. 21, 2025 — A new way to deliver disease-fighting proteins throughout the brain may improve the treatment of Alzheimer's disease and other neurological disorders, according to scientists. By engineering ...

Immune System Proteins Involved in Severe Parasitic Disease Identified

Apr. 21, 2025 — New insights into the mechanisms that cause more severe cases of schistosomiasis -- a disease caused by parasitic worms and second only to malaria in terms of potential harm -- have been ...

Recently Discovered Immune Cell Type Is Key to Understanding Food Allergies

Apr. 14, 2025 — A new study has revealed that a special group of cells in the intestines tamp down the immune responses caused by exposure to food proteins. Called 'tolerogenic dendritic cells,' these ...

Scientists Map Unprecedented Detail of Connections and Visual Perception in the Mouse Brain

Apr. 9, 2025 — In a massive scientific effort, hundreds of researchers have helped to map the connections between hundreds of thousands of neurons in the mouse brain and then overlayed their firing patterns in ...

Engineering Smart Delivery for Gene Editors

Apr. 9, 2025 — A research team has developed an advanced delivery system that transports gene-editing tools based on the CRISPR/Cas9 gene-editing system into living cells with significantly greater efficiency than ...

Researchers Find Intestinal Immune Cell Prevents Food Allergies

Apr. 3, 2025 — Researchers found that a small population of immune cells in the mouse intestine prevents allergic responses to food, suggesting that targeting such cells therapeutically could potentially lead to a ...

New Vaccine Concept Tackles Harmful Bacteria in the Intestine

Apr. 3, 2025 — In the fight against bacterial pathogens, researchers are combining vaccination with targeted colonization of the intestine by harmless microorganisms. This approach could potentially mark a turning ...

Researchers Use 'Smart' Bomb Therapy to Destroy Breast Cancer

Apr. 2, 2025 — Scientists are working to create a new light-activated 'smart' bomb to treat aggressive breast cancer. The new light-sensitive chemicals called cyanine-carborane salts are used in ...

Omega-6 Fatty Acid Promotes the Growth of an Aggressive Type of Breast Cancer, Study Finds

Apr. 1, 2025 — Linoleic acid, an omega-6 fatty acid found in seed oils such as soybean and safflower oil, and animal products including pork and eggs, specifically enhances the growth of the hard-to-treat ...

New Approach Could Treat Anthrax Beyond the 'Point of No Return'

Mar. 28, 2025 — Researchers show that a cocktail of growth factors reversed would-be lethal cell damage in mice with anthrax, suggesting that this approach could be adapted for use in ...

Understanding the Immune Response to a Persistent Pathogen

Mar. 28, 2025 — Researchers show that the immune system can recognize and control the latent stage of the parasite Toxoplasma gondii, a finding that can inform the study of latency in other infections of the nervous ...

How Did the Large Brain Evolve?

Mar. 26, 2025 — Two specific genes that evolve exclusively in humans jointly influence the development of the cerebrum. Researchers have provided evidence that these genes contribute together to the evolutionary ...

Scientists Discover Why Obesity Takes Away the Pleasure of Eating

Mar. 26, 2025 — Many obese people report losing pleasure in eating rich foods -- something also seen in obese mice. Scientists have now discovered the reason. Long-term high-fat diets lower levels of neurotensin in ...

Antibiotic Exposure in Infancy May Boost Type 1 Diabetes Risk

Mar. 25, 2025 — Exposure to antibiotics during a key developmental window in infancy can stunt growth of insulin-producing cells in the pancreas and may boost risk of diabetes later in life, new research in mice ...

'Low-Sugar' Vaccine Can Provide Broad Immunity Against Coronavirus Variants

Mar. 25, 2025 — Early animal studies show that a single vaccine could protect the recipient from different variants of the coronaviruses that cause COVID-19, the flu and the common cold. In addition to creating ...

New Eye Drops Slow Vision Loss in Animals

Mar. 21, 2025 — Researchers have developed eye drops that extend vision in animal models of a group of inherited diseases that lead to progressive vision loss in humans, known as retinitis ...

Boosting Brain's Waste Removal System Improves Memory in Old Mice

Mar. 21, 2025 — Aging compromises the lymphatic vessels surrounding the brain, disabling waste drainage from the brain and impacting cognitive function. Researchers boosted lymphatic vessel integrity in old mice and ...

New CRISPR Tool Enables More Seamless Gene Editing -- And Improved Disease Modeling

Mar. 20, 2025 — Advances in the gene-editing technology known as CRISPR-Cas9 over the past 15 years have yielded important new insights into the roles that specific genes play in many diseases. But to date this ...

Adaptive Defenses Against Malicious Jumping Genes

Mar. 20, 2025 — Adverse genetic mutations can cause harm and are due to various circumstances. 'Jumping genes' are one cause of mutations, but cells try and combat them with a specialized RNA called piRNA. ...

Groundbreaking AI Tool Generates 3D Map of the Brain

Mar. 19, 2025 — A new AI tool builds sophisticated map of mouse ...