Mice News

January 26, 2025

Top Headlines

Protein Labeling of Tens of Millions of Densely Packed Cells in Organ-Scale Tissues

Jan. 24, 2025 — Tissue processing advance can label proteins at the level of individual cells across whole, intact rodent brains and other large samples just as fast and uniformly as in dissociated single ...

Uncovering the Role of Y Chromosome Genes in Male Fertility in Mice

Jan. 23, 2025 — Researchers have uncovered which genes on the Y chromosome regulate the development of sperm and impact fertility in male mice. This research could help us understand why some men don't produce enough sperm and are ...

Fighting Experience Plays Key Role in Brain Chemical's Control of Male Aggression

Jan. 22, 2025 — Like humans, mice will compete over territory and mates, and show increased confidence in their fighting skills the more they win. At first, a brain chemical called dopamine is essential for young ...

Ancient Viral DNA Shapes Early Embryo Development

Jan. 20, 2025 — Over half of our genomes consists of thousands of remnants of ancient viral DNA, known as transposable elements, which are widespread across the tree of life. Once dismissed as the 'dark side' of the genome, researchers have now revealed their ...

Latest Headlines

updated 6:14pm EST

Your Gut Bacteria Are in a Chemical Tug-of-War With Your Body

Jan. 13, 2025 — Our gut is a bustling hub of activity, home to trillions of microbes that work together with our bodies to keep us healthy. A recent study explores one fascinating aspect of this partnership: how gut ...

The Proteins That Make Cell-to-Cell Cargo Transport Possible

Jan. 15, 2025 — Scientists have revealed the secret to the structural integrity of tiny particles that transport cargo from cell to cell through blood vessels and bodily fluids: special proteins that keep their ...

Bird Flu Is Mutating, but Antivirals Still Work

Jan. 15, 2025 — Researchers have identified nine mutations in a bird flu strain from a person in Texas. Bad news: this strain is more capable of causing disease and replicates better in the brain. Good news: ...

Gene Editing Extends Lifespan in Mouse Model of Prion Disease

Jan. 14, 2025 — Researchers have developed a gene-editing treatment for prion disease that extends lifespan by about 50 percent in a mouse model of the fatal neurodegenerative condition. The treatment, which uses ...

Self-Destructing Vaccine Offers Enhanced Protection Against Tuberculosis in Monkeys

Jan. 10, 2025 — The in-built in protection mechanisms offer a safer and more effective way to combat the deadliest disease of ...

An Earful of Gill: Evolutionary Origin of the Mammalian Outer Ear

Jan. 9, 2025 — A recent study has uncovered the surprising evolutionary origin of the mammalian outer ear, linking it to the gills of ancient fish and marine invertebrates. The research reveals that both structures ...

Cell-Based Therapy Improves Outcomes in a Pig Model of Heart Attacks

Jan. 7, 2025 — In a large-animal model study, researchers have found that heart attack recovery is aided by injection of heart muscle cell spheroids derived from human induced pluripotent stem cells, or hiPSCs, ...

Scientists Advance Nanobody Technology to Combat Deadly Ebola Virus

Jan. 7, 2025 — Ebola virus, one of the deadliest pathogens, has a fatality rate of about 50%, posing a serious threat to global health and safety. To address this challenge, researchers have developed the first ...

Researchers Discover Class of Anti-Malaria Antibodies

Jan. 3, 2025 — Antibodies that bind to a previously untargeted portion of the malaria parasite could lead to new monoclonal antibody treatments and vaccines for ...

Scientists Unveil Surprising Human Vs Mouse Differences in a Major Cancer Immunotherapy Target

Jan. 3, 2025 — Much of our knowledge of the protein PD-1, a leading cancer treatment target, comes from studies in mice. In a comprehensive assessment of PD-1, ...

Zebrafish Protein Unlocks Dormant Genes for Heart Repair

Jan. 2, 2025 — Researchers have successfully repaired damaged mouse hearts using a protein from zebrafish. They discovered that the protein Hmga1 plays a key role in heart regeneration in zebrafish. In mice, this ...

Key Players in Brain Aging: New Research Identifies Age-Related Damage on a Cellular Level

Jan. 1, 2025 — Scientists have identified the molecular changes that occur in the brains of aging mice and located a hot spot where much of that damage is centralized. The cells in the area are also connected with ...

Brain Inflammation Alters Behavior According to Sex, Mouse Study Finds

Dec. 19, 2024 — Inflammation in the hippocampus -- the brain's memory center -- significantly alters motivation and behavior in mice, according to new ...

Shiitake-Derived Functional Food Shows Suppression of Liver Fibrosis Progression

Dec. 19, 2024 — A research team found out how AHCC, a standardized extract of cultured Lentinula edodes mycelia, might be able to suppress the progression of liver ...

How a New Gut Microbe Drives the Gut-Lung Axis

Dec. 19, 2024 — A team has discovered a new communication pathway between the gut and lung. Their findings highlight how a little-known member of the gut microbiome reshapes the lung immune environment to have both ...

The Longevity Factor Foxo3 Mediates 'Unfit' Cell Elimination to Ensure Healthy Body Construction

Dec. 17, 2024 — Researchers have revealed some of the precise mechanisms by which erroneous cells are recognized, marked for removal, and eliminated via apoptosis in developing zebrafish. Notably, they found that ...

Discouraged Zebrafish Help Reveal How Ketamine Works in the Brain

Dec. 17, 2024 — By taking advantage of a 'giving up' behavior exhibited by zebrafish, the ability to image the fish's entire brain, and a unique virtual reality system, a team of researchers found ...

Flavonoid Powerhouse: Kaempferol's Role in Taming Allergic Responses

Dec. 16, 2024 — Food allergies affect millions of people worldwide, and flavonoids are promising natural compounds to help modulate the immune response and treat inflammation caused by these allergies. In a recent ...

Staphylococcus Aureus Thwarts Vaccines by Turning on a Protein That Halts Immune Response

Dec. 16, 2024 — After dozens of clinical trials, there are still no effective vaccines against Staphylococcus aureus. In two new studies, scientists report that the pathogen turns on the protein interleukin 10, ...

Researchers Discover New Neurons That Suppress Food Intake

Dec. 16, 2024 — Researchers have discovered a new population of neurons that is responsive to the hormone leptin. Leptin responsive neurons are important in obesity since leptin is sent to the brain from the ...

Intermittent Fasting Inhibits Hair Regeneration in Mice

Dec. 13, 2024 — Intermittent fasting has proven benefits for metabolic health, but a new study shows that it could slow hair growth -- at least in mice. Researchers report that mice subjected to intermittent fasting ...

The Maternal Microbiome During Pregnancy Impacts Offspring's Stem Cells in Mice

Dec. 11, 2024 — Gut microbiome composition during pregnancy has long-term effects on offspring stem cell growth and development, researchers report. Treating pregnant mice with a common gut microbe resulted in ...

A Lipid Nanoparticle Delivers mRNA Cure for Pre-Eclampsia in Mice

Dec. 11, 2024 — Engineers have developed a lipid nanoparticle (LNP) that delivers mRNA therapeutic to the placenta to treat pre-eclampsia in mice with human trials on the ...

Scientists Transform Ubiquitous Skin Bacterium Into a Topical Vaccine

Dec. 11, 2024 — Scientists' findings in mice could translate into a radical, needle-free vaccination approach that would also eliminate reactions including fever, swelling and ...

Study Breaks the Silence on How Fish and Lizards Regenerate Hearing

Dec. 9, 2024 — A new study has identified key gene regulators that enable some deafened animals -- including fish and lizards -- to naturally regenerate their hearing. The findings could guide future efforts to ...

Keto Diet Metabolite May Power Up CAR T Cells to Kill Cancer

Dec. 7, 2024 — A simple dietary supplement may provide a new approach to boost CAR T cell function, according to a new ...

CAST Mouse Model: A Crucial Tool for Future COVID-19 Outbreaks

Dec. 6, 2024 — Researchers have identified the first mouse strain that is susceptible to severe COVID-19 without the need for genetic modification. This development marks a pivotal step forward in infectious ...

Mothers Massively Change Their Intestines During Pregnancy and Nursing

Dec. 5, 2024 — When women are pregnant and nurse their babies, their bodies change and various organs, such as the breasts or the immune system, are adapted to ensure the health of both mother and child. This ...

Lasting Effects of Common Herbicide on Brain Health

Dec. 4, 2024 — New research identifies an association between glyphosate exposure in mice and symptoms of neuroinflammation, as well as accelerated Alzheimer's disease-like pathology. This study tracks both ...

The Secret to Our Big Brains Might Be in Our Gut

Dec. 4, 2024 — Brain tissue is among the most energetically costly in the body, and as a result, larger-brained mammals require more energy to support brain growth and maintenance. Exactly which biological changes ...