Alzheimer's News

November 8, 2025

Top Headlines

Scientists Find Hidden Brain Source That Fuels Dementia

Nov. 6, 2025 — Weill Cornell researchers uncovered how free radicals from astrocyte mitochondria can fuel dementia. Using new compounds that target these radicals at their source, they slowed brain inflammation and neuronal damage in mice. The findings reveal a ...

Scientists May Have Found How to Reverse Memory Loss in Aging Brains

Nov. 5, 2025 — Virginia Tech researchers have shown that memory loss in aging may be reversible. Using CRISPR tools, they corrected molecular disruptions in the hippocampus and amygdala, restoring memory in older rats. Another experiment revived a silenced memory ...

Alzheimer’s Might Be Powered by a Broken Sleep-wake Cycle

Nov. 3, 2025 — Disrupted sleep patterns in Alzheimer’s disease may be more than a symptom—they could be a driving force. Researchers at Washington University found that the brain’s circadian rhythms are thrown off in key cell types, changing when hundreds of ...

Scientists Reverse Alzheimer’s in Mice with Groundbreaking Nanotech

Oct. 30, 2025 — Researchers used supramolecular nanoparticles to repair the brain’s vascular system and reverse Alzheimer’s in mice. Instead of carrying drugs, the nanoparticles themselves triggered natural clearance of amyloid-β proteins. This restored ...

A “Toxic Duo” May Be the Hidden Trigger Behind Alzheimer’s Disease

Oct. 22, 2025 — Scientists have uncovered a toxic alliance between Aβ and fibrinogen that may explain how Alzheimer’s disease begins. The two proteins together create stubborn clots that damage blood vessels and spark inflammation in the brain. These effects ...

These 80-year-olds Have the Memory of 50-year-olds. Scientists Finally Know Why

Oct. 19, 2025 — SuperAgers defy normal aging by keeping sharp memories and healthy brains well into their 80s. Northwestern scientists discovered that these individuals either resist the buildup of harmful brain ...

Supercharged Vitamin K Could Help the Brain Heal Itself

Oct. 14, 2025 — Researchers have synthesized enhanced vitamin K analogues that outperform natural vitamin K in promoting neuron growth. The new compounds, which combine vitamin K with retinoic acid, activate the mGluR1 receptor to drive neurogenesis. They also ...

Think Light Drinking Protects Your Brain? Think Again

Oct. 4, 2025 — A massive new study combining observational and genetic data overturns the long-held belief that light drinking protects the brain. Researchers found that dementia risk rises in direct proportion to alcohol consumption, with no safe level ...

Fat May Secretly Fuel Alzheimer’s, New Research Finds

Oct. 3, 2025 — New research from Houston Methodist reveals how obesity may directly drive Alzheimer’s disease. Scientists discovered that tiny messengers released by fat tissue, called extracellular vesicles, can carry harmful signals that accelerate the buildup ...

Hidden Alzheimer’s Warning Signs Found in Parkinson’s Patients Without Dementia

Sep. 28, 2025 — Researchers in Japan discovered that Parkinson’s patients diagnosed in their 80s are far more likely to show signs of amyloid buildup, a hallmark of Alzheimer’s, even without dementia symptoms. ...

Brain Fat, Not Just Plaques, May Be the Hidden Driver of Alzheimer’s

Sep. 24, 2025 — For decades, scientists believed Alzheimer’s was driven mainly by sticky protein plaques and tangles in the brain. Now Purdue researchers have revealed a hidden culprit: fat. They found that brain immune cells can become clogged with fat, leaving ...

Sleepless Nights May Raise Dementia Risk by 40%, Mayo Clinic Reveals

Sep. 14, 2025 — Chronic insomnia may do more than leave you groggy, it could speed up brain aging. A large Mayo Clinic study found that people with long-term sleep troubles were 40% more likely to develop dementia or cognitive impairment, with brain scans showing ...

Latest Headlines

updated 11:46am EST

Walking May Be the Brain’s Best Defense Against Alzheimer’s

Nov. 4, 2025 — Walking a few thousand steps daily may help hold off Alzheimer’s for years, a Mass General Brigham study found. Even moderate physical activity slowed both cognitive decline and the buildup of ...

Simple Blood Test Could Spot Alzheimer’s Years Before Symptoms

Sep. 9, 2025 — Scientists discovered that certain blood proteins linked to brain injury and inflammation strongly correlate with early signs of memory and cognitive decline, especially in Hispanic and Latino ...

A 3-Minute Brainwave Test Could Spot Alzheimer’s Years Before Symptoms

Sep. 4, 2025 — Scientists at the University of Bath have developed a simple three-minute brainwave test called Fastball EEG that can detect memory problems years before Alzheimer’s is typically diagnosed. Unlike ...

Stronger Weed, Higher Risk? Potent THC Linked to Psychosis and Addiction

Sep. 2, 2025 — A sweeping review of nearly 100 studies has raised concerns about the mental health impacts of high-potency cannabis products. Researchers found strong links to psychosis, schizophrenia, and cannabis ...

Lithium Deficiency May Be the Hidden Spark Behind Alzheimer’s

Aug. 29, 2025 — Harvard scientists have uncovered that lithium, a naturally occurring element in the brain, may be the missing piece in understanding Alzheimer’s. Their decade-long research shows that lithium ...

Cannabis for Coping? Why It May Trigger Paranoia

Aug. 28, 2025 — Using cannabis to self-medicate comes with hidden dangers—new research shows these users face higher paranoia and consume more THC. Childhood trauma further amplifies the risks, especially ...

Tiny Protein Dismantles the Toxic Clumps Behind Alzheimer’s

Aug. 23, 2025 — St. Jude researchers revealed that midkine blocks amyloid beta from forming harmful clumps linked to Alzheimer’s. Without it, the damaging assemblies accelerate, but with it, growth halts. The ...

The Hidden Mental Health Danger in Today’s High-THC Cannabis

Aug. 12, 2025 — THC levels in cannabis have soared in recent years, raising the risk of psychosis—especially in young, frequent users. Studies reveal a strong connection between cannabis-induced psychosis and ...

Scientists Reversed Memory Loss by Powering the Brain’s Tiny Engines

Aug. 12, 2025 — Scientists have discovered a direct cause-and-effect link between faulty mitochondria and the memory loss seen in neurodegenerative diseases. By creating a novel tool to boost mitochondrial activity ...

Think It’s Just Aging? Why Dementia Is Missed for 3.5 Years on Average

July 28, 2025 — Many people with dementia endure long delays often over 3 years before receiving a diagnosis, with even longer waits for younger patients. A global review of over 30,000 cases reveals that age, ...

Scientists Discover the Receptor That Helps Your Brain Clean Itself—and Fight Alzheimer’s

July 27, 2025 — Scientists at UCSF have uncovered how certain immune cells in the brain, called microglia, can effectively digest toxic amyloid beta plaques that cause Alzheimer’s. They identified a key receptor, ...

Iron Overload: The Hidden Culprit Behind Early Alzheimer’s in Down Syndrome

June 20, 2025 — USC researchers have uncovered a hidden driver behind the early and severe onset of Alzheimer's in people with Down syndrome: iron overload in the brain. Their study revealed that individuals ...

Immune System Discovery Reveals Potential Solution to Alzheimer's

June 2, 2025 — A new way of thinking about Alzheimer's disease has yielded a discovery that could be the key to stopping the cognitive decline seen in Alzheimer's and other neurodegenerative diseases, ...

Common Gene Variant Doubles Dementia Risk for Men

May 30, 2025 — New research has found that men who carry a common genetic variant are twice as likely to develop dementia in their lifetime compared to ...

Research Untangles Role of Stress Granules in Neurodegenerative Disease

May 28, 2025 — Scientists found that stabilizing stress granules suppresses the effects of ALS-causing mutations, correcting previous models that imply stress granules promote amyloid ...

Whether It's Smoking or Edibles, Marijuana Can Be Bad for Your Heart, Study Suggests

May 28, 2025 — A new study finds that chronic cannabis use -- whether it's smoked or consumed in edible form -- is associated with significant cardiovascular ...

Study Reveals Impacts of Alzheimer's Disease on the Whole Body

May 16, 2025 — While Alzheimer's disease is mostly considered a disorder of the brain, emerging evidence suggests that the condition also affects other organs of the body. Working with the laboratory fruit ...

Energy and Memory: A New Neural Network Paradigm

May 14, 2025 — Listen to the first notes of an old, beloved song. Can you name that tune? If you can, congratulations -- it's a triumph of your associative memory, in which one piece of information (the first ...

Sugar-Coated Nanotherapy Dramatically Improves Neuron Survival in Alzheimer's Model

May 14, 2025 — In many neurodegenerative diseases, proteins misfold and clump together in brain tissue. Scientists developed a new therapy made of peptides and a sugar that naturally occurs in plants. The ...

Knowing Your Alzheimer's Risk May Ease Anxiety but Reduce Motivation for Healthy Habits

May 7, 2025 — Discovering whether the brain carries early signs of Alzheimer’s doesn’t necessarily spark fear or sadness—in fact, people often feel less anxious after learning their results. But there’s a ...

Most People Say They Want to Know Their Risk for Alzheimer's Dementia, Fewer Follow Through

May 6, 2025 — A new study examines the choices healthy research volunteers make when given the opportunity to learn their risk of developing Alzheimer's disease dementia. The researchers found a large ...

Increasing Physical Activity in Middle Age May Protect Against Alzheimer's Disease

Apr. 30, 2025 — An increase in physical activity between the ages of 45 and 65 could help prevent Alzheimer's disease, while inactivity may be detrimental to brain ...

Low Iron Could Cause Brain Fog During Menopause Transition

Apr. 28, 2025 — New research sheds light on an understudied area of science: iron levels in the blood and their relationship to cognitive performance in women transitioning into menopause. The findings are good news ...

First Synthetic 'Mini Prion' Shows How Protein Misfolding Multiplies

Apr. 28, 2025 — Prions transmit their abnormally folded shape onto other proteins. Researchers designed a synthetic fragment of the tau protein that exhibits prion-like behavior. Misfolded tau proteins are the ...

Immune Cells Drive Congenital Paralysis Disease

Apr. 25, 2025 — Patients with spastic paraplegia type 15 develop movement disorders during adolescence that may ultimately require the use of a wheelchair. In the early stages of this rare hereditary disease the ...

Study Shows Addressing Working Memory Can Help Students With Math Difficulty Improve Word Problem-Solving Skills

Apr. 21, 2025 — Working memory is like a mental chalkboard we use to store temporary information while executing other tasks. Scientists worked with more than 200 elementary students to test their working memory, ...

Engineered Microglia Show Promise for Treating Alzheimer's and Other Brain Diseases

Apr. 21, 2025 — A new way to deliver disease-fighting proteins throughout the brain may improve the treatment of Alzheimer's disease and other neurological disorders, according to scientists. By engineering ...

Hereditary Alzheimer's: Blood Marker for Defective Neuronal Connections Rises Early

Apr. 16, 2025 — Individuals with a genetic predisposition to Alzheimer's disease show altered blood levels indicating damaged neuronal contacts as early as 11 years before the expected onset of dementia ...

Scientists Identify Key Enzyme in Alzheimer's Disease That Links Brain Inflammation to Memory Loss

Apr. 14, 2025 — A research team has identified a previously unknown enzyme, SIRT2, that plays a key role in memory loss associated with Alzheimer's disease (AD). The study provides critical insights into how ...

ALS Drug Effectively Treats Alzheimer's Disease in New Animal Study

Apr. 8, 2025 — Experimental drug NU-9 -- a small molecule compound approved by the U.S. Food and Drug Administration (FDA) for clinical trials for the treatment of amyotrophic lateral sclerosis (ALS) -- improves ...