New! Sign up for our free email newsletter.

Controlled Substances News

March 2, 2026

Top Headlines

 

Scientists are taking a closer look at the pill forms of Wegovy and Ozempic. In an animal study, the ingredient SNAC, which helps semaglutide survive the stomach and enter the bloodstream, was ...
A groundbreaking clinical trial is testing whether specially engineered stem cells can help the brain restore its own dopamine production in people with Parkinson’s disease. Because the condition is driven by the gradual loss of dopamine-producing ...
A sweeping new study has uncovered a troubling mix of hazardous chemicals in popular hair extensions, including products made from human hair. Researchers detected dozens of substances linked to cancer, hormone disruption, reproductive harm, and ...
A new University at Buffalo study suggests cannabis-infused beverages could help some people cut back on alcohol. In a survey of cannabis users, those who drank cannabis beverages reported cutting their weekly alcohol intake roughly in half and ...
New research using rhesus monkeys suggests that the brain’s relationship with alcohol may begin forming long before a person ever takes a drink. Scientists found that exposure to alcohol before birth reshaped the brain’s dopamine system, a key ...
A new study suggests that micro-doses of THC could help counter many long-term side effects of HIV treatment without causing intoxication. In animal models, low-dose THC reduced inflammation, improved gut bacteria, boosted serotonin, and lowered ...
Cannabis-based medicines have been widely promoted as a potential answer for people living with chronic nerve pain—but a major new review finds the evidence just isn’t there yet. After analyzing more than 20 clinical trials involving over 2,100 ...
Bariatric surgery far outperformed GLP-1 weight loss drugs in a new real-world comparison of more than 50,000 patients. Two years after treatment, surgery patients lost about 58 pounds on average, while those using semaglutide or tirzepatide lost ...
Cannabis products with higher THC levels may slightly reduce chronic pain, particularly nerve pain, according to a review of multiple clinical trials. The improvement was small and short-lived, while side effects were more common. Products with ...
A new study shows dopamine isn’t the brain’s movement “gas pedal” after all. Instead of setting speed or strength, it quietly enables movement in the background, much like oil in an engine. When scientists manipulated dopamine during ...
More than 20% of young adults say they use cannabis or alcohol to fall asleep, with cannabis leading by a wide margin. Researchers warn this strategy can backfire, disrupting sleep quality and increasing the risk of long-term sleep and substance-use ...
Scientists exploring how the brain responds to stress discovered molecular changes that can influence behavior long after an experience ends. They also identified natural resilience systems that help protect certain individuals from harm. These ...

Latest Headlines

updated 12:49pm EST

Earlier Headlines

 

Scientists are uncovering how GLP-1 drugs like Ozempic and Wegovy act on brain regions that control hunger, nausea, pleasure-based eating, and thirst. These discoveries may help create treatments ...

Scientists discovered that alcohol activates a sugar-producing pathway in the body, creating fructose that may reinforce addictive drinking. The enzyme responsible, KHK, appears to drive both alcohol ...

Researchers developed a new nano-micelle formulation, CBD-IN, that finally gets CBD into the brain effectively. In mice, it relieved neuropathic pain quickly and didn’t cause the usual movement or ...

Scientists found that people who use both cannabis and tobacco show a distinct brain pattern tied to mood and stress regulation. Their scans revealed higher levels of an enzyme that reduces a natural ...

A major collaboration between UC San Diego and 23andMe identified genes that shape cannabis use behaviors. The study linked the CADM2 and GRM3 genes to cannabis use and connected these patterns to ...

Overdose deaths from fentanyl mixed with stimulants have skyrocketed among seniors, increasing 9,000% in just eight years. Once thought to affect mainly the young, the opioid epidemic’s fourth wave ...

GLP-1 drugs, originally developed for diabetes and obesity, may also curb addictive behaviors by acting on reward circuits in the brain. Early trials show reductions in alcohol intake, opioid ...

Generalized anxiety disorder affects millions, often trapping sufferers in cycles of fear and isolation that conventional medications barely relieve. At UCSF, neuroscientist Jennifer Mitchell is ...

Over 40% of fatal crash victims had THC levels far above legal limits, showing cannabis use before driving remains widespread. The rate didn’t drop after legalization, suggesting policy changes ...

Penn researchers found that psilocybin can calm brain circuits tied to pain and mood, easing both physical suffering and emotional distress in animal studies. The compound works in the anterior ...

Researchers found that middle-aged adults, especially women, are far more likely to be addicted to ultra-processed foods than older generations. Marketing of diet-focused processed foods in the 1980s ...

Nitazenes, a powerful and largely hidden class of synthetic opioids, are quickly becoming a deadly factor in the overdose crisis. Over 20 times stronger than fentanyl, these drugs often go undetected ...

Some people taking Ozempic, Wegovy, or Mounjaro notice that food suddenly tastes sweeter or saltier, and this subtle shift in flavor perception appears tied to reduced appetite and stronger feelings ...

A massive study of over 4 million adults has revealed that cannabis use may nearly quadruple the risk of developing diabetes. Despite some earlier suggestions that cannabis might have metabolic ...

Addiction often isn’t about chasing pleasure—it’s about escaping pain. Researchers at Scripps Research have discovered that a tiny brain region called the paraventricular nucleus of the ...

Researchers have created a two-stage acne patch with tiny arrowhead-shaped spikes that deliver healing compounds directly under the skin. Trials showed pimples vanished in seven days, and the ...

Using powerful 7-Tesla brain imaging, researchers mapped how the brainstem manages pain differently across the body. They discovered that distinct regions activate for facial versus limb pain, ...

Overactivation of dopamine neurons may directly drive their death, explaining why movement-controlling brain cells degenerate in Parkinson’s. Mice with chronically stimulated neurons showed the ...

A long-term study following insomnia patients treated with cannabis-based medical products revealed sustained improvements in sleep quality, mood, and pain management over 18 months. Most ...

Using cannabis to self-medicate comes with hidden dangers—new research shows these users face higher paranoia and consume more THC. Childhood trauma further amplifies the risks, especially ...

Tuesday, November 18, 2025

Saturday, November 15, 2025

Monday, October 20, 2025

Monday, October 13, 2025

Sunday, October 26, 2025

Monday, October 27, 2025

Sunday, October 5, 2025

Thursday, October 2, 2025

Monday, September 29, 2025

Thursday, September 18, 2025

Tuesday, September 16, 2025

Sunday, September 14, 2025

Monday, October 6, 2025

Saturday, September 20, 2025

Tuesday, November 4, 2025

Wednesday, September 3, 2025

Tuesday, September 2, 2025

Thursday, August 28, 2025

Tuesday, September 2, 2025

Wednesday, September 10, 2025

Tuesday, August 12, 2025

Friday, August 1, 2025

Thursday, July 24, 2025

Tuesday, July 22, 2025

Thursday, October 23, 2025

Thursday, July 3, 2025

Tuesday, July 1, 2025

Friday, November 7, 2025

Saturday, June 28, 2025

Tuesday, June 3, 2025

Saturday, June 7, 2025

Monday, June 2, 2025

Wednesday, May 28, 2025

Thursday, May 22, 2025

Wednesday, May 14, 2025

Thursday, May 8, 2025

Wednesday, May 7, 2025

Monday, May 5, 2025

Thursday, May 1, 2025

Wednesday, April 30, 2025

Tuesday, April 29, 2025

Monday, April 28, 2025

Thursday, April 24, 2025

Monday, April 21, 2025

Wednesday, April 16, 2025

Monday, April 14, 2025

Thursday, April 10, 2025

Wednesday, April 9, 2025

Tuesday, April 8, 2025

Monday, April 7, 2025

Thursday, April 3, 2025

Wednesday, April 2, 2025

Friday, March 28, 2025

Wednesday, March 26, 2025

Tuesday, March 25, 2025

Friday, March 21, 2025

Wednesday, March 19, 2025

Tuesday, March 18, 2025

Monday, March 17, 2025

Friday, March 14, 2025

Wednesday, March 12, 2025

Sunday, March 9, 2025

Wednesday, March 5, 2025

Monday, March 3, 2025

Thursday, February 27, 2025

Wednesday, February 26, 2025

Tuesday, February 25, 2025

Friday, February 21, 2025

Thursday, February 20, 2025

Wednesday, February 19, 2025

Thursday, February 13, 2025

Wednesday, February 12, 2025

Tuesday, February 11, 2025

Monday, February 10, 2025

Thursday, February 6, 2025

Wednesday, February 5, 2025

Monday, February 3, 2025

Thursday, January 30, 2025

Tuesday, January 28, 2025