Brain Tumor News

November 20, 2024

Top Headlines

Glioblastoma: New Treatment Attacks Brain Tumors from Multiple Angles

Nov. 12, 2024 — Glioblastoma is the most common kind of malignant brain tumor in adults. So far, no treatment has been able to make this aggressive tumor permanently disappear. The tumor cells are too varied, and the microenvironment is too tumor-friendly. ...

Researchers Make Glioblastoma Cells Visible to Attacking Immune Cells

Nov. 7, 2024 — Researchers have identified a possible way to make glioblastoma cells vulnerable to different types of immunotherapy. The strategy, which they demonstrated in cells in the lab, forces brain cancer cells to display targets for the immune system to ...

Researchers Home in on Tumor Vulnerabilities to Improve Odds of Treating Glioblastoma

Nov. 4, 2024 — Researchers have uncovered new targets that could be the key to effectively treating glioblastoma, a lethal type of brain cancer. These targets were identified through a screen for genetic ...

Repurposing Drug Shows Promise in Fighting Aggressive Brain Tumors

Oct. 17, 2024 — Research provides evidence that a drug used to slow the progression of the disease ALS shows promise in suppressing the self-renewing cancerous stem cells that challenge the present standards of care for these lethal grade 4 brain ...

Latest Headlines

updated 10:46pm EST

Study Explores Novel Therapeutic Treatment for Glioblastoma

Oct. 7, 2024 — Researchers discovered combining the brain-penetrating antipsychotic drug pimozide with a clinically investigative glutamine metabolism inhibitor, CB-839, can overcome tumor resistance and ...

Antidepressant Shows Promise for Treating Brain Tumors

Sep. 20, 2024 — Researchers have used a drug screening platform they developed to show that an antidepressant, currently on the market, kills tumor cells in the dreaded glioblastoma -- at least in the cell-culture ...

Antibody-Drug Conjugate Found Effective Against Brain Metastases in Patients With HER2-Positive Breast Cancer

Sep. 13, 2024 — A drug that delivers chemotherapy directly to tumors has shown impressive activity against some of the hardest-to-reach cancer cells: those that have ...

How the Scars of Demolished Brain Tumors Seed Relapse

Sep. 9, 2024 — A study has discovered that recurrent tumors of the aggressive brain cancer glioblastoma multiforme (GBM) grow out of the fibrous scars of malignant predecessors destroyed by interventions such as ...

Human Brain Cancers Fire Electrical Impulses -- Researchers Reveal Unexpected Hybrid Cell Spiking the Signals

Sep. 5, 2024 — Researcher have uncovered a new cell type in the human brain that fires electrical impulses. The cells are hybrids, part neuron and part glia, and ...

Adolescent Glioma Subtype Responds to CDK4/6 Inhibitor

Sep. 3, 2024 — Researchers took a deep look at tumor samples from patients with diffuse hemispheric glioma and discovered an unexpected vulnerability to CDK4/6 ...

New Study Uncovers Key Mechanisms Responsible for the Transformation of Adult Progenitors Into Brain Tumors

Sep. 3, 2024 — A new study sheds light on why certain oligodendrocyte progenitor cells (OPCs) in the adult brain transform into gliomas, the most common and ...

Study Shows New, More Precise Way to Deliver Medicine to the Brain

Aug. 9, 2024 — Researchers have discovered a more accurate and timely way to deliver life-saving drug therapies to the brain, laying the groundwork for more effective treatment of brain tumors and other ...

Drug-Chemo Combo Increases Cancer Treatment Efficacy

July 30, 2024 — A new study finds that giving a fatty acid inhibitor alongside chemotherapy could improve the treatment efficacy for patients with brain metastases from triple negative breast ...

Researchers Develop Promising Therapy Treatment That Can Kill Glioblastoma Cells in Newly Discovered Brain Pathway

Aug. 2, 2024 — A new pathway that is used by cancer cells to infiltrate the brain has been discovered. The research also reveals a new therapy that shows promise in ...

NK Cells Expressing Interleukin-21 Show Promising Antitumor Activity in Glioblastoma Cells

Aug. 12, 2024 — Natural killer (NK) cells engineered to express interleukin-21 (IL-21) demonstrated sustained antitumor activity against glioblastoma stem cell-like cells (GSCs) both in vitro and in vivo, according ...

Surprising Finding in Glioblastomas

July 31, 2024 — Glioblastomas are highly aggressive, usually incurable brain tumors. If all therapeutic options are exhausted, patients have an average life expectancy of less than two years. Now researchers have ...

Electrical Currents May Make Body's Cancer-Killing Cells Even Better Killers

July 25, 2024 — Scientists have discovered that electrical currents may make Natural Killer (NK) cells -- our very own cancer-killing immune cells -- even better killers, which could have significant implications ...

Tumor Suppressor Protein Par-4 Triggers Unique Cell Death Pathway in Cancerous Cells

July 23, 2024 — A team of researchers has discovered that the tumor suppressor protein Prostate apoptosis response-4 (Par-4) can cause a unique type of cell death called ferroptosis in human glioblastoma -- the most ...

New Technique Could Help Treat Aggressive Brain Tumors

July 17, 2024 — Burst sine wave electroporation was found to cause less damage to cells and tissue but more disruption to the blood-brain ...

Study Points at Novel Approach to Treat Group 3 Medulloblastoma

July 9, 2024 — A team of researchers has identified and located a population of stem-like cells that initiates and maintains Group 3 medulloblastoma (Gr3-MB) in the developing brain. Gr3-MB is one of the most ...

Scientists Exploring Potential New Treatments for Glioblastoma

July 8, 2024 — A new approach to treating the most malignant type of brain cancer -- glioblastoma -- has shown strong promise in pre-clinical settings, raising hopes of increasing current average survival rates ...

How to Stop Cancer Cachexia? Start at the Top

July 8, 2024 — Researchers have discovered a new potential drug target for the lethal wasting disease known as cancer cachexia. Their findings illustrate that even small groups of neurons in the brain can have an ...

Already 30 Minutes of Exercise Increases the Proportion of Tumor-Killing White Blood Cells in Blood

July 3, 2024 — A new study shows that already a 30-minute exercise can increase the proportion of tumor-killing white blood cells in the bloodstream of breast cancer ...

More Effective Cancer Treatment With Iontronic Pump

June 19, 2024 — When low doses of cancer drugs are administered continuously near malignant brain tumors using so-called iontronic technology, cancer cell growth drastically decreases. Researchers demonstrated this ...

Pediatric Brain Tumors Rely on Different Metabolic 'Route' to Fuel Treatment Resistance

June 13, 2024 — Researchers are one step closer to understanding how pediatric DIPG tumors ...

Study Identifies Potential Pathway to Reducing Breast Cancer Brain Metastases

June 7, 2024 — A study has identified a biological mechanism that could lead to more effective treatments for breast cancer that has metastasized to the ...

New Glioblastoma Treatment Reaches Human Brain Tumor and Helps Immune Cells Recognize Cancer Cells

June 6, 2024 — In a major advance for the treatment of the deadly brain cancer glioblastoma, scientists used ultrasound technology to penetrate the blood-brain barrier and provide a small dose of a chemotherapy and ...

New Research Platform Assesses Brain Cancer Mutations During Surgery

May 30, 2024 — Brain cancer is difficult to treat when it starts growing, and a prevalent type, known as a glioma, has a poor five-year survival rate. In a new study, researchers report on a new surgical platform ...

Scientists Uncover Promising Treatment Target for Resistant Brain Cancer

May 20, 2024 — For many patients with a deadly type of brain cancer called glioblastoma, chemotherapy resistance is a big problem. But now, researchers may have moved a step closer to a ...

New Immunosuppressive Mechanism Found in Brain Cancer

May 3, 2024 — Scientists have discovered how glioblastoma evades the immune system by inducing pro-tumor macrophages via a glucose based epigenetic ...

New mRNA Cancer Vaccine Triggers Fierce Immune Response to Fight Malignant Brain Tumor

May 1, 2024 — An mRNA cancer vaccine quickly reprogrammed the immune system to attack the most aggressive type of brain tumor in a first-ever human clinical ...

Genetically Engineering a Treatment for Incurable Brain Tumors

Apr. 22, 2024 — Scientists are developing and validating a patent-pending novel immunotherapy to be used against glioblastoma brain tumors. Glioblastomas are almost always lethal with a median survival time of 14 ...

'Dual-Target' Cell Therapy Appears to Shrink Brain Tumors, Research Finds

Mar. 13, 2024 — Targeting two brain tumor-associated proteins -- rather than one -- with CAR T cell therapy shows promise as a strategy for reducing solid tumor growth in patients with recurrent glioblastoma (GBM), ...

Zika Virus Vaccine Emerges as an Unlikely Hero in Battling Brain Cancer

Mar. 8, 2024 — Scientists have developed a new approach using the Zika virus to destroy brain cancer cells and inhibit tumor growth, while sparing healthy ...