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Computational neuroscience

Computational Neuroscience is an interdisciplinary science that links the diverse fields of neuroscience, computer science, physics and applied mathematics together. It serves as the primary theoretical method for investigating the function and mechanism of the nervous system. Computational neuroscience is distinct from psychological connectionism and theories of learning from disciplines such as machine learning, neural networks and statistical learning theory in that it emphasizes descriptions of functional and biologically realistic neurons and their physiology and dynamics. These models capture the essential features of the biological system at multiple spatial-temporal scales, from membrane currents, protein and chemical coupling to network oscillations and learning and memory. These computational models are used to test hypotheses that can be directly verified by current or future biological experiments.

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Mind & Brain News

January 14, 2026

A massive international brain study has revealed that memory decline with age isn’t driven by a single brain region or gene, but by widespread structural changes across the brain that build up over time. Analyzing thousands of MRI scans and memory ...
Despite longstanding guidelines, many dementia patients are still prescribed brain-altering medications that can raise the risk of falls and confusion. A new study shows that while prescribing has decreased overall, people with cognitive impairment ...
Researchers have discovered a brain activity pattern that can predict which people with mild cognitive impairment are likely to develop Alzheimer’s disease. Using a noninvasive brain scanning technique and a custom analysis tool, they detected ...
A large review of studies suggests that exercise can ease depression about as effectively as psychological therapy. Compared with antidepressants, exercise showed similar benefits, though the evidence was less certain. Researchers found that light ...
Teens who sleep in on weekends may be giving their mental health a boost. A new study found that young people who made up for lost weekday sleep had a significantly lower risk of depression. While consistent sleep is still best, weekend catch-up ...
A familiar mouth bacterium best known for causing cavities may also be quietly influencing the brain. Scientists found that when this microbe settles in the gut, it produces compounds that can travel through the bloodstream and harm neurons involved ...
Many people with multiple sclerosis struggle with balance and coordination, and this study uncovers a hidden reason why. Researchers found that inflammation in the brain disrupts the energy supply of vital movement-controlling neurons. As their ...
A long-running debate over Tamiflu’s safety in children may finally be settled. Researchers found that influenza, not the antiviral medication, was linked to serious neuropsychiatric events like seizures and hallucinations. Even more striking, ...
Nearly all women in STEM graduate programs report feeling like impostors, despite strong evidence of success. This mindset leads many to dismiss their achievements as luck and fear being “found out.” Research links impostorism to worse mental ...
New research shows gut bacteria can directly influence how the brain develops and functions. When scientists transferred microbes from different primates into mice, the animals’ brains began to resemble those of the original host species. Microbes ...
Researchers compared a traditional Chinese medicine, Yueju Pill, with a standard antidepressant and found both reduced depression symptoms. However, only Yueju Pill increased a brain-supporting protein associated with mood improvement. Brain imaging ...
New research shows that AI doesn’t need endless training data to start acting more like a human brain. When researchers redesigned AI systems to better resemble biological brains, some models produced brain-like activity without any training at ...

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updated 12:56 pm ET