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The new season of The Last of Us has a spore-ting chance at realism

Date:
April 7, 2025
Source:
University of British Columbia
Summary:
The Last of Us is back on April 13 and this season is more realistic than ever. The trailer for the hit HBO series appears to show the 'zombie fungus' cordyceps infecting humans by releasing air-borne spores, instead of through tentacles -- closer to scientific reality. And it's not the only thing the show gets right.
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The Last of Us is back on April 13 and this season is more realistic than ever.

The trailer for the hit HBO series appears to show the "zombie fungus" cordyceps infecting humans by releasing air-borne spores, instead of through tentacles -- closer to scientific reality.

Spread the love (and spores)

"Fungi love to make spores," says Dr. Jim Kronstad, a professor and microbiologist at UBC's Michael Smith Laboratories. Real-life cordyceps colonizes ant brains, causing the insect to climb to a high branch. The fungus then punches through the ant's head and rains spores down on the forest floor.

Indeed, many fungal diseases than infect humans, such as Cryptococcus neoformans, which causes meningitis in humans, are spread by inhaling spores.

It's not the only thing the show gets right. In The Last of Us, cordyceps -- which is harmless, even edible, in real life -- evolved into a harmful fungus thanks to a warming climate.

In a recent Nature paper, Dr. Kronstad and co-authors highlight a warming climate as a potential contributor to the spread of harmful fungi like Coccidioides, which causes valley fever, and the current rise of Candida auris, which infects hospitalized patients and is resistant to available antifungal drugs.

The authors also noted the discovery of a new fungus last year, Rhodosporidiobolus fluvialis, in humans, which had previously been found only in the environment.

Fungi can be fun guys

Fungi aren't all bad. They recycle dead organic material and serve as huge carbon sinks. They can be used to make strong, lightweight materials, including materials that could be used in space. We use fungi in a range of foods and ingredients, including in vegan burgers. "Fungi are super important, it's phenomenal what they've done for humans," adds Dr. Kronstad.


Story Source:

Materials provided by University of British Columbia. Original written by Alex Walls. Note: Content may be edited for style and length.


Journal Reference:

  1. Nicola T. Case, Sarah J. Gurr, Matthew C. Fisher, David S. Blehert, Charles Boone, Arturo Casadevall, Anuradha Chowdhary, Christina A. Cuomo, Cameron R. Currie, David W. Denning, Iuliana V. Ene, Lillian K. Fritz-Laylin, Aleeza C. Gerstein, Neil A. R. Gow, Asiya Gusa, Iliyan D. Iliev, Timothy Y. James, Hailing Jin, Regine Kahmann, Bruce S. Klein, James W. Kronstad, Kyla S. Ost, Kabir G. Peay, Rebecca S. Shapiro, Donald C. Sheppard, Neta Shlezinger, Jason E. Stajich, Eva H. Stukenbrock, John W. Taylor, Gerard D. Wright, Leah E. Cowen, Joseph Heitman, Julia A. Segre. Fungal impacts on Earth’s ecosystems. Nature, 2025; 638 (8049): 49 DOI: 10.1038/s41586-024-08419-4

Cite This Page:

University of British Columbia. "The new season of The Last of Us has a spore-ting chance at realism." ScienceDaily. ScienceDaily, 7 April 2025. <www.sciencedaily.com/releases/2025/04/250407114240.htm>.
University of British Columbia. (2025, April 7). The new season of The Last of Us has a spore-ting chance at realism. ScienceDaily. Retrieved April 7, 2025 from www.sciencedaily.com/releases/2025/04/250407114240.htm
University of British Columbia. "The new season of The Last of Us has a spore-ting chance at realism." ScienceDaily. www.sciencedaily.com/releases/2025/04/250407114240.htm (accessed April 7, 2025).

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