Pernicious effects of stigma

"What we're seeing today is a close examination of the hardships and indignities that people have faced for a very long time because of their race and ethnicity," said Kyle Ratner, an assistant professor of psychological and brain sciences at UC Santa Barbara. As a social psychologist, he is interested in how social and biological processes give rise to intergroup bias and feelings of stigmatization.

According to Ratner, "It is clear that people who belong to historically marginalized groups in the United States contend with burdensome stressors on top of the everyday stressors that members of non-disadvantaged groups experience. For instance, there is the trauma of overt racism, stigmatizing portrayals in the media and popular culture, and systemic discrimination that leads to disadvantages in many domains of life, from employment and education to healthcare and housing to the legal system."

Concerned by negative rhetoric directed at Latinx individuals, Ratner and his lab have investigated how negative stereotype exposure experienced by Mexican-American students can influence the way their brains process information.

In a recent paper published in the journal Social Cognitive and Affective Neuroscience, the research team focuses on how negative stereotype exposure affects responses to monetary incentives. Their finding: The brains of Mexican-American students exposed to negative stereotypes anticipate rewards and punishments differently versus those who were not so exposed. The discovery, he said, is the first step in a series of studies that could help researchers understand neural pathways through which stigma can have detrimental effects on psychological and physical health.

'I'm so tired of this'

Much existing research has focused on how experiencing stigma and discrimination triggers anger, racing thoughts and a state of high arousal. Although Ratner believes this is a reaction that people experience in some contexts, his recent work focuses on the psychological fatigue of hearing your group disparaged. "It's this feeling of 'oh, not again,' or 'I'm so tired of this,'" he said, describing a couple of reactions to the stress of managing self-definition in the face of negative stereotypes.

While noticing several years ago that experiencing stigma can produce this sense of withdrawal and resignation, Ratner was reminded of work he conducted earlier in his career relating stress to depressive symptoms.

"In work I was involved in over a decade ago, we showed that life stress can be associated with anhedonia, which is a blunted sensitivity to positive and rewarding information, such as winning money," he said. "If you're not sensitive to the rewarding things in life, you're basically left being sensitive to all the frustrating things in life, without that positive buffer. And that's one route to depression."

Given that experiencing stigma can be conceptualized as a social stressor, Ratner wanted to investigate whether negative stereotype exposure might also relate to sensitivity to reward.

Reward Processing in the Brain

Ratner and his colleagues focused on the nucleus accumbens, a sub-cortical brain region that plays a central role in anticipating pleasure -- the "wanting" stage of reward processing that motivates behaviors.

Using functional MRI to measure brain activity, the researchers asked Mexican-American UCSB students to view sets of video clips in rapid succession and then gave these students the opportunity to win money or avoiding losing money.

In the control group, the viewers were shown news and documentary clips of social problems in the United States that were relevant to the country in general -- childhood obesity, teen pregnancy, gang violence and low high school graduation numbers.

In the stigmatized group, subjects were shown news and documentary clips covering the same four domains, but that singled out the Latinx community as the group specifically at risk for these problems.

"These videos were not overtly racist," Ratner said of the stigmatizing clips. Rather, he explained, the videos tended to spend a disproportionate amount of attention on the association between specific social issues and their effects in the Latinx community, rather than presenting them as problems of American society as a whole. The clips were mostly from mainstream news agencies -- the newscasters and narrators, he said, appeared to be "presenting facts as they understood them," but the content of these clips reinforced negative stereotypes.

After repeated exposure to negative stereotypes, the research participants were asked to perform a Monetary Incentive Delay (MID) task, which required them to push a button whenever they saw a star on the screen. Pressing the button fast enough resulted in either winning money or avoiding losing money.

In those individuals shown the stigmatizing clips, the nucleus accumbens responded differently to waiting for the star to appear, as compared to those who viewed the control clips, a pattern that suggests that negative stereotype exposure was "spilling-over" to affect how participants were anticipating winning and losing money.

"We saw that something about watching these stigmatizing videos was later influencing the pattern of response within this brain region," Ratner said. This suggests that the nucleus accumbens is representing the potential of winning and losing money differently in the brains of those who previously saw the stigmatizing videos than those who didn't, he explained. The researchers also found that the group that saw the stigmatizing videos reported lower levels of arousal right before starting the MID task, consistent with stigmatizing experiences having a demotivating effect.

"The nucleus accumbens is very important for motivated behavior, and sparks of motivation are important for many aspects for everyday life," Ratner said. A loss of motivation, he continued, is often experienced by those who perceive their situation as out of their control.

One reason negative stereotypes in the media and popular culture are so problematic is they make people feel stigmatized even when they are not personally targeted in their daily life by bigoted people, he explained. "It becomes something you can't escape -- similar to other stressors that are out of people's control and have been shown to cause anhedonia."

Ratner is careful to point out that this study merely scratches the surface of brain processes involved in intergroup reactions such as stigma -- how the brain processes social motivations is far more complex and necessitates further study.

"People shouldn't generalize too much from this specific finding," he said, pointing out that his sample of 40 Mexican-American college students, while not small for a brain imaging study, represents only a small segment of a far more diverse community. When his lab is back up and running following the COVID-19 related cessation, he said, he and his collaborators hope to study a larger, non-student sample.

Other members of Ratner's research team include lead author and former UCSB postdoctoral fellow B. Locke Welborn and current UCSB Ph.D. student Youngki Hong.