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Antidepressants reduce deaths by more than a third in patients with diabetes

Date:
July 2, 2019
Source:
The Endocrine Society
Summary:
Antidepressants reduce deaths by more than a third in patients with diabetes and depression, according to a new study.
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Antidepressants reduce deaths by more than a third in patients with diabetes and depression, according to a study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

People with diabetes are two to three times more likely to have depression than people without diabetes, according to the U.S. Centers for Disease Control and Prevention. Half to three-quarters of people with diabetes and depression go undiagnosed, despite therapy and medicine being very effective.

"The incidence of major depressive disorder amongst individuals with diabetes is significantly greater than the general population," said the study's corresponding author, Vincent Chin-Hung Chen, Professor, of Chiayi Chang Gung Memorial Hospital and Chang Gung University in Puzi, Taiwan. "Diabetes and depression each independently contribute to increasing total mortality."

In this large population-based study, researchers used the National Health Insurance Research Database in Taiwan to identify 53,412 patients diagnosed with diabetes and depression since 2000. The researchers followed this population until 2013 to see if antidepressants reduced the death rate. They found that antidepressants significantly reduced mortality by 35 percent.

"This data provides further rationale for the screening and treating of depression in persons who have diabetes," Chen said.


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Materials provided by The Endocrine Society. Note: Content may be edited for style and length.


Journal Reference:

  1. Hong-Ming Chen, Yao-Hsu Yang, Ko-Jung Chen, Yena Lee, Roger S McIntyre, Mong-Liang Lu, Yi-Chen Lee, Ming-Chia Hsieh, Vincent Chin-Hung Chen. Antidepressants reduced risk of mortality in patients with diabetes mellitus: a population-based cohort study in Taiwan. The Journal of Clinical Endocrinology & Metabolism, 2019; DOI: 10.1210/jc.2018-02362

Cite This Page:

The Endocrine Society. "Antidepressants reduce deaths by more than a third in patients with diabetes." ScienceDaily. ScienceDaily, 2 July 2019. <www.sciencedaily.com/releases/2019/07/190702112838.htm>.
The Endocrine Society. (2019, July 2). Antidepressants reduce deaths by more than a third in patients with diabetes. ScienceDaily. Retrieved March 28, 2024 from www.sciencedaily.com/releases/2019/07/190702112838.htm
The Endocrine Society. "Antidepressants reduce deaths by more than a third in patients with diabetes." ScienceDaily. www.sciencedaily.com/releases/2019/07/190702112838.htm (accessed March 28, 2024).

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