Healthier hearts equal healthier guts

In this first-of-its-kind study, just published in the International Journal of Sport Nutrition and Exercise Metabolism, recent SF State graduate student Ryan Durk and Assistant Professor of Kinesiology Jimmy Bagley partnered with the SF State Health Equity Research (HER) Lab to test the relationship between gut health and cardiovascular fitness.

Durk (who received his master's degree in kinesiology last December) recruited 20 men and 17 women, mostly from the SF State campus, and tested their cardiovascular fitness on a treadmill. He also assessed their body composition in the lab's BOD POD, an air displacement chamber that determines a person's fat and fat-free mass. Participants kept food logs for seven days and provided stool samples at the end of the week. The HER Lab then extracted DNA to analyze the bacteria composition in the samples. The researchers were investigating the ratio of bacteria called firmicutes to another group, bacteroides, which can be used to gauge overall gut health and composition.

Analysis showed that participants with the best cardiovascular fitness had a higher firmicutes to bacteroides ratio. While most gut bacteria can be beneficial (even bacteroides in some cases), firmicutes bacteria are associated with metabolic byproducts that help prevent bacteria in the gut from leaking into the body. "These metabolic byproducts help strengthen the intestinal lining and help prevent leaky gut syndrome," said Durk. He says this research reinforces the idea of "exercise as medicine."

"When we say that phrase, we think of it as meaning that exercise will help people stay healthier and live longer. But you don't think about your gut bacteria," Durk said. "We now know that exercise is crucial for increasing beneficial bacteria in the gut."

According to Durk, findings from this study and other studies about the gut microbiome could eventually be used to create individual exercise prescriptions to improve gut -- and overall -- health. "We're not there yet," he said, "but this helps create that foundation."

Durk, who returned to SF State last semester as a lecturer in kinesiology, recently presented his research at the American College of Sports Medicine (ACSM) Annual Meeting in Minneapolis.