Warning: High-intensity training could hurt you if you're not an athlete

A study by Canadian and European researchers found signs of stress in the muscle tissues of their non-athlete, untrained subjects after ultra-intense leg and arm cycling exercises. Perhaps more concerning, researchers reported the untrained subjects had a weakened ability to fight off free radicals, molecules that can alter DNA and harm healthy cells.

"Our study raises questions about what the right dose and intensity of exercise for the average person really is," said Robert Boushel, the study's senior author and director of the University of British Columbia's School of Kinesiology. "We need to be cautious about supporting sprint training in the general population."

The researchers analyzed tissue samples from their test subjects and found that their mitochondria, the powerhouse of cells, were only firing at half-power post-training, reducing their capacity to consume oxygen and their ability to fight off damage from free radicals. High levels of free radicals in the body have been linked to a number of medical conditions, including cancer, premature aging and organ damage.

The potential long-term adverse effects of high-intensity sprint training are unknown, but Boushel and other researchers are continuing to study different levels of exercise, measuring the dosing of training against different biomarkers for health.

"If you're new to going to the gym, participating in high-intensity 'sprint' classes may increase your performance but might not be healthy for you," said Boushel.

Seasoned athletes and those who are well trained have built up antioxidant enzymes in their bodies to protect against free radicals, said Boushel. He recommended beginners start slowly and gradually increase intensity over time, under the supervision of a trained professional or kinesiologist.

Background

The study was carried out in a dozen male volunteers in Sweden, all of whom were in good health but self-identified as untrained or only moderately active. The men participated in high-intensity training over the course of two weeks that involved repeated 30-second all-out sprints, followed by rest periods.

The study, "High-intensity sprint training inhibits mitochondrial respiration through aconitase inactivation," is published in The Official Journal of the Federation of American Societies for Experimental Biology (FASEB) Journal.