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Immune Signals Of Variations Of A Single Gene Linked To More Severe Crohn's Disease

Date:
May 23, 2006
Source:
Cedars-Sinai Medical Center
Summary:
A recent study has shown that immune signals given by variations of a single gene can trigger different immune responses and, when combined, are associated with increased severity of Crohn's Disease, particularly in Ashkenazi Jews. The study is being presented at the annual meeting of the American Gastroenterological Association May 20-25 in Los Angeles.
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Building on previous evidence supporting the theory that the pathophysiology of Crohn's Disease is altered by genetic variation, recent studies have found that the combination of immune signals given by three variants of a single candidate gene affects the severity of the disease, particularly among Ashkenazi Jews. The findings, presented at the annual meeting of the American Gastroenterological Association, were reported by researchers from Cedars-Sinai Medical Center, the University of Washington and Mount Sinai School of Medicine.


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Materials provided by Cedars-Sinai Medical Center. Note: Content may be edited for style and length.


Cite This Page:

Cedars-Sinai Medical Center. "Immune Signals Of Variations Of A Single Gene Linked To More Severe Crohn's Disease." ScienceDaily. ScienceDaily, 23 May 2006. <www.sciencedaily.com/releases/2006/05/060523085937.htm>.
Cedars-Sinai Medical Center. (2006, May 23). Immune Signals Of Variations Of A Single Gene Linked To More Severe Crohn's Disease. ScienceDaily. Retrieved October 10, 2025 from www.sciencedaily.com/releases/2006/05/060523085937.htm
Cedars-Sinai Medical Center. "Immune Signals Of Variations Of A Single Gene Linked To More Severe Crohn's Disease." ScienceDaily. www.sciencedaily.com/releases/2006/05/060523085937.htm (accessed October 10, 2025).

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