
How Small Molecule Can Take Apart Alzheimer's Disease Protein Fibers
Researchers have shown, in
unprecedented detail, how a
small molecule is able to
selectively take apart
abnormally folded protein
fibers connected to
... > full story

Scientists Find New Causes For Neurodegeneration
Diseases that cause neurons
to break down, such as
Alzheimer's, continue to be
elusive to scientists and
resistant to treatments. A
new finding demonstrates an
... > full story

Prions May Activate Retroviruses In Infected Brain Cells
Prion proteins may activate
endogenous retroviruses in
infected brain cells. Prions
– an abbreviation for
proteinaceous infectious
particles – work as a
... > full story

Researchers Develop Resin Beads That Capture Mad Cow Disease Agent From Blood
For the first time,
experimental results
indicate that it is possible
to use a resin filter to
remove harmful prion
... > full story
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Protective Pathway In Stressed Cells Not So Helpful When It Comes To Prions
September 17, 2008 Scientists have discovered that an important cellular quality control mechanism may actually be toxic to some brain cells during prion infection. The research proposes a new general mechanism of ... > full story -
Variant Of Mad Cow Disease May Be Transmitted By Blood Transfusions, According To Animal Study
August 29, 2008 Blood transfusions are a valuable treatment mechanism in modern medicine, but can come with the risk of donor disease transmission. Researchers are continually studying the biology of blood products ... > full story -
First Atomic-level Look At A Protein That Causes Brain Disease
April 24, 2008 For the first time, researchers have peered deeply at the atomic level into the protein that causes hereditary cerebral amyloid angiopathy -- a disease thought to cause stroke and dementia. The study ... > full story -
Prions Link Cholesterol To Neurodegeneration
February 12, 2008 Prion infection of neurons increases the free cholesterol content in cell membranes. A new study suggests that disturbances in membrane cholesterol may be the mechanism by which prions cause ... > full story -
Chemists Characterize Alzheimer's Neurotoxin Structure
December 7, 2007 Chemists have characterized the molecular structure of the intermediate stage of plaque-forming amyloid fibrils, believed to cause Alzheimer's disease. The finding may lead to new drug targets for ... > full story -
Prion Fingerprints Detected With Glowing Molecule
November 22, 2007 An effective and sensitive new method for detecting and characterizing prions, the infectious compounds behind diseases like mad cow disease, is now being launched. Mad cow disease (BSE), which has ... > full story -
Small Clumps Of Prion Proteins May Be Primary Cause Of Neurodegenerative Diseases
September 10, 2007 Scientists have shown for the first time that small clumps of abnormal prion proteins called oligomers cause the widespread death of neurons. In contrast, much larger prion aggregates known as ... > full story -
Newly Discovered Prion Protein May Offer Insight Into Mad Cow Disease
August 17, 2007 Scientists have discovered a new protein that may offer fresh insights into brain function in mad cow ... > full story -
Alzheimer's Prevention Role Discovered For Prions
July 6, 2007 A role for prion proteins, the much debated agents of mad cow disease and vCJD, has been identified. It appears that the normal prions produced by the body help to prevent the plaques that build up ... > full story -
Manganese Levels Increase In Scrapie-infected Sheep Before Clinical Symptoms Develop
July 4, 2007 Sheep infected with scrapie and cows infected with BSE have elevated levels of manganese in their blood before clinical symptoms appear, according to new ... > full story
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