Dementia News

August 5, 2025

Top Headlines

Alzheimer’s Risk May Start at the Brain’s Border, Not Inside It

Aug. 4, 2025 — Your brain has its own elite defense team — and new research shows these "guardian" cells might be the real battleground for neurological diseases like Alzheimer’s and stroke. Scientists discovered that most genetic risks linked to these ...

Scientists Discover the Receptor That Helps Your Brain Clean Itself—and Fight Alzheimer’s

July 27, 2025 — Scientists at UCSF have uncovered how certain immune cells in the brain, called microglia, can effectively digest toxic amyloid beta plaques that cause Alzheimer’s. They identified a key receptor, ...

The Silent Threat: How Hearing Loss and Loneliness Are Fueling Memory Decline

July 18, 2025 — A massive European study has uncovered a powerful connection between hearing loss, loneliness, and memory decline. Researchers at the University of Geneva found that older adults with hearing ...

Scientists Just Found 200+ Hidden Proteins That May Drive Alzheimer’s

July 12, 2025 — A surprising new study has uncovered over 200 misfolded proteins in the brains of aging rats with cognitive decline, beyond the infamous amyloid and tau plaques long blamed for Alzheimer’s. These shape-shifting proteins don’t clump into visible ...

Researchers Grow 400+ Brain Cell Types—a Leap for Alzheimer’s and Parkinson’s Research

July 12, 2025 — Scientists at ETH Zurich have broken new ground by generating over 400 types of nerve cells from stem cells in the lab, far surpassing previous efforts that produced only a few dozen. By ...

Your Brain’s Hidden Defenses Against Alzheimer’s

July 10, 2025 — Scientists at UCSF combined advanced brain-network modeling, genetics, and imaging to reveal how tau protein travels through neural highways and how certain genes either accelerate its toxic journey or shield brain regions from damage. Their ...

A Midlife MRI That Spots Rapid Aging and Signals Disease Long Before Symptoms

July 2, 2025 — A new brain scan tool shows how quickly your body and mind are aging. It can spot early signs of diseases like dementia, long before symptoms begin. The scan looks at hidden clues in your brain to ...

Scientists Just Found a Sugar Switch That Protects Your Brain from Alzheimer's

June 30, 2025 — Scientists have uncovered a surprising sugar-related mechanism inside brain cells that could transform how we fight Alzheimer’s and other dementias. It turns out neurons don’t just store sugar ...

This Brain Scan Sees Alzheimer’s Coming—but Only in Some Brains

June 29, 2025 — USC researchers have found a promising new brain scan marker that could better detect Alzheimer’s risk — but only for some. The tau-based benchmark works in Hispanic and White populations when paired with another Alzheimer’s protein, amyloid, ...

The Brain’s Sweet Spot: How Criticality Could Unlock Learning, Memory—and Prevent Alzheimer’s

June 25, 2025 — Our brains may work best when teetering on the edge of chaos. A new theory suggests that criticality a sweet spot between order and randomness is the secret to learning, memory, and adaptability. ...

The Common Blood Test That Predicts How Fast Alzheimer’s Hits

June 22, 2025 — A simple blood test could reveal which early Alzheimer’s patients are most at risk for rapid decline. Researchers found that people with high insulin resistance—measured by the TyG index—were four times more likely to experience faster ...

Iron Overload: The Hidden Culprit Behind Early Alzheimer’s in Down Syndrome

June 21, 2025 — USC researchers have uncovered a hidden driver behind the early and severe onset of Alzheimer's in people with Down syndrome: iron overload in the brain. Their study revealed that individuals with ...

Latest Headlines

updated 12:02pm EDT

The Hunger Switch in Your Nose: How Smells Tell Your Brain to Stop Eating

June 12, 2025 — A team of scientists has discovered a direct link between the smell of food and feelings of fullness at least in lean mice. This brain circuit, located in the medial septum and triggered by food ...

Immune System Discovery Reveals Potential Solution to Alzheimer's

June 2, 2025 — A new way of thinking about Alzheimer's disease has yielded a discovery that could be the key to stopping the cognitive decline seen in Alzheimer's and other neurodegenerative diseases, including ALS ...

Sharing of Lifespan Brain Study Data Expected to Light New Paths

May 30, 2025 — Researchers have released the full dataset from the Dallas Lifespan Brain Study, a decade-long project designed to track brain and cognitive health as people age and distinguish neurologically ...

Newly Identified Group of Nerve Cells in the Brain Regulates Bodyweight

May 30, 2025 — Obesity is a global health problem that affects many people. In recent years, very promising anti-obesity drugs have been developed. Despite these successes, there are patients who do not respond to ...

Sustained in the Brain: How Lasting Emotions Arise from Brief Stimuli, in Humans and Mice

May 29, 2025 — Humans and mice share persistent brain-activity patterns in response to adverse sensory experience, scientists find, opening a window to our emotions ...

New Pace of Aging Measurement Reveals Trajectories of Healthspan and Lifespan in Older People

May 28, 2025 — A newly refined method for measuring the Pace of Aging in population-based studies provides a powerful tool for predicting risks associated with ...

Different Versions of APOE Protein Have Varying Effect on Microglia in Alzheimer's Disease

May 27, 2025 — A new study suggests how APOE2 is protective while APOE4 increases disease risk by regulating the brain's immune ...

Potential New Treatment for Alzheimer's Disease, Other Neurodegenerative Conditions

May 26, 2025 — Worldwide, more than 55 million people suffer from dementia caused by Alzheimer's Disease (AD) and other conditions that destroy cells in the brain ...

New Research on ALS Opens Up for Early Treatment

May 20, 2025 — Using the gene scissors CRISPR and stem cells, researchers have managed to identify a common denominator for different gene mutations that all cause the neurological disease ALS. The research shows ...

Study Reveals Impacts of Alzheimer's Disease on the Whole Body

May 17, 2025 — While Alzheimer's disease is mostly considered a disorder of the brain, emerging evidence suggests that the condition also affects other organs of the body. Working with the laboratory fruit fly, ...

Sugar-Coated Nanotherapy Dramatically Improves Neuron Survival in Alzheimer's Model

May 14, 2025 — In many neurodegenerative diseases, proteins misfold and clump together in brain tissue. Scientists developed a new therapy made of peptides and a sugar that naturally occurs in plants. The ...

CAR-T Cell Therapy for Cancer Causes 'Brain Fog,' Study Shows

May 12, 2025 — Cancer treatment with a cell-based immunotherapy causes mild cognitive impairment, a Stanford Medicine team found. They also identified compounds that could treat ...

Drug to Slow Alzheimer's Well Tolerated Outside of Clinical Trial Setting

May 12, 2025 — In a recent study, researchers found adverse events were rare and manageable among clinic patients with very mild or mild Alzheimer's disease who received lecanemab ...

HIV Drugs Offer 'Substantial' Alzheimer's Protection, New Research Indicates

May 8, 2025 — The drugs, called NRTIs, have the potential to prevent a million cases of Alzheimer's every year, the researchers ...

Sleep Apnea During REM Sleep Linked to Memory-Related Brain Changes

May 7, 2025 — Obstructive sleep apnea, a condition that causes lower oxygen levels during sleep, is linked to degeneration of brain regions associated with memory through damage to the brain's small blood ...

Knowing Your Alzheimer's Risk May Ease Anxiety but Reduce Motivation for Healthy Habits

May 7, 2025 — Learning about one's risk for Alzheimer's disease may not lead to emotional distress, but motivation to maintain healthy lifestyle changes tends to fade over time, even in people at high ...

Most People Say They Want to Know Their Risk for Alzheimer's Dementia, Fewer Follow Through

May 6, 2025 — A new study examines the choices healthy research volunteers make when given the opportunity to learn their risk of developing Alzheimer's disease dementia. The researchers found a large ...

A Protein Link Between Brain Diseases and Leaky Blood Vessels

Apr. 30, 2025 — Reduced levels of a critical protein are linked to devastating brain diseases like Alzheimer's, frontotemporal dementia, and amyotrophic lateral sclerosis (ALS). Surprisingly, the protein ...

Increasing Physical Activity in Middle Age May Protect Against Alzheimer's Disease

Apr. 30, 2025 — An increase in physical activity between the ages of 45 and 65 could help prevent Alzheimer's disease, while inactivity may be detrimental to brain ...

Researchers Find That Increase of 'CLU' Protein Promotes Brain Resilience and Could Provide Protection from Alzheimer's Disease

Apr. 30, 2025 — Recently approved Alzheimer's drugs offer a step forward for treating the disease, but new therapeutic strategies are needed to complement them and provide personalized therapeutic approaches. ...

First Synthetic 'Mini Prion' Shows How Protein Misfolding Multiplies

Apr. 28, 2025 — Prions transmit their abnormally folded shape onto other proteins. Researchers designed a synthetic fragment of the tau protein that exhibits prion-like behavior. Misfolded tau proteins are the ...

AI Helps Unravel a Cause of Alzheimer's Disease and Identify a Therapeutic Candidate

Apr. 25, 2025 — A new study found that a gene recently recognized as a biomarker for Alzheimer's disease is actually a cause of it, due to its previously unknown secondary function that triggers a pathway that ...

Even Light Exercise Could Help Slow Cognitive Decline in People at Risk of Alzheimer's

Apr. 24, 2025 — In a landmark clinical trial people at risk for Alzheimer's who exercised at low or moderate-high intensity showed less cognitive decline when compared to those receiving usual ...

Exercise Boosts Brain Health -- Even When Energy Is Low

Apr. 24, 2025 — We know exercise is good for our body, but what about our brains? A new study suggests that exercise plays a crucial role in keeping our minds sharp, even when one of the brain's key energy ...

Clinical Trials to Test Vaccine Against Alzheimer's-Promoting Tau Protein

Apr. 23, 2025 — Researchers hope to launch human clinical trials in their quest for a vaccine to prevent the buildup of pathological tau after demonstrating that this vaccine generated a robust immune response in ...

ATP Prevents Harmful Aggregation of Proteins Associated With Parkinson's and ALS

Apr. 23, 2025 — While a comprehensive cure-all to these neurological conditions is unlikely, scientists are making headway into understanding their fundamental characteristics with the hope of preventing or ...

Empathy Might Be Retained in Alzheimer's Disease

Apr. 23, 2025 — People with Alzheimer's disease may retain their ability to empathize, despite declines in other social abilities, finds a new ...

New Research Lays Groundwork for Early Detection of Alzheimer's Disease

Apr. 21, 2025 — A new study suggests that risk factors and biomarkers related to Alzheimer's disease are associated with cognition much earlier in life than previously recognized. The study highlights ...

Engineered Microglia Show Promise for Treating Alzheimer's and Other Brain Diseases

Apr. 21, 2025 — A new way to deliver disease-fighting proteins throughout the brain may improve the treatment of Alzheimer's disease and other neurological disorders, according to scientists. By engineering ...

Integrative Approach Reveals Promising Candidates for Alzheimer's Disease Risk Factors or Targets for Therapeutic Intervention

Apr. 18, 2025 — A new study provides solutions to the pressing need to identify factors that influence Alzheimer's disease (AD) risk or resistance while providing an avenue to explore potential biological ...