Umbilical cord milking appears to be safe in preterm infants born after 28 weeks
- Date:
- November 9, 2023
- Source:
- NIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development
- Summary:
- A treatment to move blood from the umbilical cord into an infant's body may provide a safe option for preterm infants born after 28 weeks who need rapid support, suggests a new study. The procedure, called umbilical cord milking, involves gently squeezing the cord between the thumb and forefinger and pushing the blood into the newborn's abdomen. The new findings suggest that concerns raised by a 2019 study of infants born before 28 weeks -- which concluded that umbilical cord milking might increase the risk of bleeding inside the brain -- do not apply to preterm infants born after 28 weeks.
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A treatment to move blood from the umbilical cord into an infant's body may provide a safe option for preterm infants born after 28 weeks who need rapid support, suggests a study supported by the National Institutes of Health. The procedure, called umbilical cord milking, involves gently squeezing the cord between the thumb and forefinger and pushing the blood into the newborn's abdomen. The new findings suggest that concerns raised by a 2019 study of infants born before 28 weeks -- which concluded that umbilical cord milking might increase the risk of bleeding inside the brain -- do not apply to preterm infants born after 28 weeks. The current study appears in Pediatrics.
The standard procedure, delaying cord clamping while blood naturally flows into the infant's body, takes 30 to 180 seconds. However, cord milking, takes about 20 seconds, reducing delay for infants who need immediate assistance, such as respiratory support. Both procedures allow for umbilical cord blood to reach the infant's body before clamping, reducing the risk of anemia and other complications seen among infants receiving immediate cord clamping and cutting.
The study was conducted by Anup Katheria, M.D., of the Sharp Mary Birch Hospital for Women & Newborns in San Diego, and colleagues in the United States, Canada and Europe. It was supported by NIH's Eunice Kennedy Shriver National Institute of Child Health and Human Development.
More than 1,000 infants were randomly assigned either to umbilical cord milking or delayed cord clamping. Rates of severe intraventricular hemorrhage (bleeding inside the brain) and/or death did not differ significantly between the two groups (just over 1%). Moreover, the rates of overall intraventricular hemorrhage were also similar between the groups (approximately 12%). The researchers will follow all the infants in the study for two years to observe longer term outcomes.
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Materials provided by NIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development. Note: Content may be edited for style and length.
Journal Reference:
- Anup Katheria, Jeff Szychowski, Waldemar A Carlo, Akila Subramaniam, Frank Reister, Jochen Essers, Farha Vora, Courtney Martin, Georg M. Schmölzer, Brenda Law, Eugene Dempsey, Keelin O’Donoghue, Joseph Kaempf, Mark Tomlinson, Kevin Fulford, Bergen Folsom, Simon Karam, Rachael Morris, Toby Yanowitz, Stacy Beck, Erin Clark, Tara DuPont, Manoj Biniwale, Rangasamy Ramanathan, Shazia Bhat, Matthew Hoffman, Nitin Chouthai, Fayez Bany-Mohammed, Janardhan Mydam, Vivek Narendran, Fiona Wertheimer, Yvonne Gollin, Yvonne Vaucher, Kathy Arnell, Michael Varner, Gary Cutter, Nicole Wilson, Wade Rich, Neil Finer. Umbilical Cord Milking Versus Delayed Cord Clamping in Infants 28 to 32 Weeks: A Randomized Trial. Pediatrics, 2023; DOI: 10.1542/peds.2023-063113
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