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Human genome

The human genome is the genome of Homo sapiens. It is made up of 23 chromosome pairs with a total of about 3 billion DNA base pairs. There are 24 distinct human chromosomes: 22 autosomal chromosomes, plus the sex-determining X and Y chromosomes. Chromosomes 1-22 are numbered roughly in order of decreasing size. Somatic cells usually have one copy of chromosomes 1-22 from each parent, plus an X chromosome from the mother, and either an X or Y chromosome from the father, for a total of 46. There are an estimated 20,000-25,000 human protein-coding genes. The estimate of the number of human genes has been repeatedly revised down from initial predictions of 100,000 or more as genome sequence quality and gene finding methods have improved, and could continue to drop further.

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Health & Medicine News

September 12, 2025

Walking every day could be the simplest and most effective way to prevent chronic lower back pain. A large study involving over 11,000 people found that walking more — not faster — reduces the risk of developing long-term back issues. The ...
Forever chemicals known as PFAS have turned up in an unexpected place: beer. Researchers tested 23 different beers from across the U.S. and found that 95% contained PFAS, with the highest concentrations showing up in regions with known water ...
Researchers have discovered that everyday substances like caffeine can influence how bacteria such as E. coli respond to antibiotics. By examining 94 common drugs and food ingredients, scientists found that certain compounds trigger genetic ...
New research suggests that immunotherapy given before and after surgery could help patients with diffuse pleural mesothelioma, one of the most challenging cancers to treat. A phase II clinical trial tested immunotherapy in resectable cases, with ...
Researchers at NYU Langone Health discovered that cutting off blood flow accelerates cancer growth by prematurely aging the bone marrow and weakening the immune system. In mouse models, restricted blood flow doubled the growth rate of breast tumors, ...
Scientists in Canada have uncovered a surprising culprit behind high blood sugar and liver problems: a hidden fuel made by gut bacteria. This little-known molecule, called D-lactate, slips into the ...
Glioblastoma’s stealthy spread has met a new challenge: MRI-powered fluid flow mapping that reveals where the cancer is likely to invade next. The innovation is now being advanced by a spinoff company to guide personalized cancer ...
Scientists at Stellenbosch University have uncovered a rare class of plant compounds, flavoalkaloids, in Cannabis leaves for the first time. Using advanced two-dimensional chromatography and mass spectrometry, they identified 79 phenolic compounds ...
Metformin, long trusted for diabetes, turns out to work in the brain too. By shutting down Rap1 in the hypothalamus, the drug lowers blood sugar more effectively than previously understood, opening doors for new ...
What we eat as we age may determine how many chronic illnesses we face later in life. A 15-year study of more than 2,400 older adults reveals that diets rich in vegetables, whole grains, nuts, and healthy fats slow the accumulation of diseases like ...
Scientists discovered that certain blood proteins linked to brain injury and inflammation strongly correlate with early signs of memory and cognitive decline, especially in Hispanic and Latino adults. This breakthrough points to a future where ...
Thousands of women are using GLP-1 drugs like Ozempic for weight loss without contraception, leading to unintended pregnancies and potential risks for unborn babies. Experts warn clearer medical guidance is urgently ...

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updated 12:56 pm ET