Students engineer socks for on-the-go neuropathy treatment

Rice engineering students in the StimuSock team -- Abby Dowse, Yannie Guo, Andrei Mitrofan, Sarah Park and Kelly Xu -- designed a sock with a smart insole that can deliver both transcutaneous electrical nerve stimulation (TENS) and vibration therapy that block pain signals to the brain and provide haptic feedback to help with balance issues, respectively.

The team will present its device at the annual Oshman Engineering Design Kitchen showcase and competition April 13 at the Ion.

According to the Centers for Disease Control and Prevention's 2022 estimates, over 37 million people in the U.S. suffer from diabetes. About half of them will develop some form of diabetic neuropathy, a type of nerve damage that occurs most often in the legs and feet.

The StimuSock team sought to combine the best aspects of existing therapies into a single, user-centered design.

"Existing products or devices used to treat the symptoms of diabetic neuropathy are either pharmaceuticals or large at-home vibration devices users stand on," Dowse said. "But none of them can both treat pain and improve balance, which our device aims to do by combining the TENS and the vibrational therapy in one wearable, portable, user-controllable and easy-to-use device."

A lot of the team's effort went into making the device as low-profile as possible.

"The intent is for the patient to be able to wear the device for the whole day," Guo said. "Even when everything's off and they don't want the electrostimulation or haptics effect, they can still wear their device. … You don't want it to look like you're wearing an ankle monitor."

Patients use a smartphone app to control the type, intensity and duration of the desired therapeutic stimulus. The system also allows users to target a specific area of the foot.

"We have three regions: one in the front of the insole, one in the middle and one at the back," Park said. "Our aim is to allow patients to be able to control both the amplitude of the vibration and the location where it's delivered. Some patients might only want vibration at the front of their feet and some only at the back."

Mitrofan said the team anticipates the device's final form will have sufficient battery life to provide the recommended maximum of four 30-minute sessions of TENS therapy per day and operate on standby the rest of the day.

The team's mentor is bioengineering assistant teaching professor Sabia Abidi .