Microfountain pen draws minute patterns for live cells, circuits

In Review of Scientific Instruments, from AIP Publishing, researchers from Germany and China outline the development of a flexible and easy-to-use micropen setup, capable of directly writing on surfaces to a microprecise level.

The micropen is held over an ink reservoir as ink is drawn into the pen nozzle. Once filled, the nozzle is positioned for writing onto a tabletop surface.

When the pen meets the surface, ink transfers from the nozzle, and the robot arm is manually manipulated for desired patterns. When the writing is complete, the pen is removed from the surface.

"The setup is an example of how easy and intuitively micromanipulator-based micropatterning can be, and how complex structures that are not compatible with conventional lithography approaches can be accessed," said author Michael Hirtz.

Microarrays, lines, curves, and other structures can be printed in real time using the micropen, and could be used in biological or microelectronic labs, using biomaterial or conductive ink to pattern live cells or circuits. The pen also has potential applications that include molding, embossing, aerosol printing, and inkjet printing.

"By using our setup, or similarly designed ones, it will be possible to pattern into existing devices, microreactors, or hard-to-reach surfaces, on the fly and intuitively," said Hirtz. "This micropen can work with many different types of inks, in a timely and suitable way, enabling users to write in a controlled, microprecise level."