Viruses could be harder to kill after adapting to warm environments

Enteroviruses can cause infections as benign as a cold or as dangerous as polio. Found in feces, they are released into the environment from sewage and other sources. Their subsequent survival depends on their ability to withstand the environmental conditions they encounter. Because globalization and climate change are expected to alter those conditions, Anna Carratalà, Tamar Kohn and colleagues wanted to find out how viruses might adapt to such shifts and how this would affect their disinfection resistance.

The team created four different populations of a human enterovirus by incubating samples in lake water in flasks at 50 F or 86 F, with or without simulated sunlight. The researchers then exposed the viruses to heat, simulated sunlight or microbial "grazing" and found that warm-water-adapted viruses were more resistant to heat inactivation than cold-water-adapted ones. Little or no difference was observed among the four strains in terms of their inactivation when exposed to either more simulated sunlight or other microbes. When transplanted to cool water, warm-water-adapted viruses also remained active longer than the cool-water strains. In addition, they withstood chlorine exposure better. In sum, adaptation to warm conditions decreased viral susceptibility to inactivation, so viruses in the tropics or in regions affected by global warming could become tougher to eliminate by chlorination or heating, the researchers say. They also say that this greater hardiness could increase the length of time heat-adapted viruses would be infectious enough to sicken someone who comes in contact with contaminated water.