A Chemical 'Keypad Lock' For Biomolecular Computers

Evgeny Katz and colleagues describe development of a chemical "keypad lock," one of the first chemical-based security systems of its kind. The researchers note that years of effort have gone into developing biomolecular computers, which rely on chemical reactions rather than silicon chips to perform logic functions. Among their uses would be encryption of financial, military, and other confidential information. Only individuals with access to a secret "key" -- a chemical key -- could unlock the file and access the data.

The research by Katz and colleagues solved one part of this technological challenge: The security code. They identified a series of naturally occurring chemical reactions that act as a "keypad lock." In laboratory studies, they demonstrated that by adding the correct series of chemicals, the lock could be opened to access the computer. On the other hand, adding the incorrect chemicals to the system acts as a wrong password and prevents access to the computer, they say.

"In addition to the biomolecular security applications, the enzyme-based implication logic networks will be extremely important for making autonomous decisions on the use of specific tools/drugs in various implantable medical systems."

Journal reference: The article "Biocomputing Security System: Concatenated Enzyme-Based Logic Gates Operating as a Biomolecular Keypad Lock" is scheduled for the March 26 issue of ACS' Journal of the American Chemical Society. (http://dx.doi.org/10.1021/ja7114713)